BBC additions & removals
Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.
Additions
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| TRAX | FIRST TRACKS BIOTHERAPEUTICS INC | 2026-04-30 | Added / first present |
| RAPT | RAPT Therapeutics Inc | 2026-01-30 | Added / first present |
| VTYX | Ventyx Biosciences Inc | 2026-01-30 | Added / first present |
| ALMS | Alumis Inc | 2026-01-30 | Added / first present |
| AMLX | Amylyx Pharmaceuticals Inc | 2026-01-30 | Added / first present |
| ASMB | Assembly Biosciences Inc | 2026-01-30 | Added / first present |
| ATAI | AtaiBeckley Inc | 2026-01-30 | Added / first present |
| CMPX | Compass Therapeutics Inc | 2026-01-30 | Added / first present |
| CTMX | CytomX Therapeutics Inc | 2026-01-30 | Added / first present |
| DFTX | Definium Therapeutics Inc | 2026-01-30 | Added / first present |
| ENGN | Engene Holdings Inc | 2026-01-30 | Added / first present |
| FDMT | 4D Molecular Therapeutics Inc | 2026-01-30 | Added / first present |
| FULC | Fulcrum Therapeutics Inc | 2026-01-30 | Added / first present |
| GOSS | Gossamer Bio Inc | 2026-01-30 | Added / first present |
| INBX | Inhibrx Biosciences Inc | 2026-01-30 | Added / first present |
| IRWD | Ironwood Pharmaceuticals Inc | 2026-01-30 | Added / first present |
| IVVD | Invivyd Inc | 2026-01-30 | Added / first present |
| JBIO | Jade Biosciences Inc | 2026-01-30 | Added / first present |
| KOD | Kodiak Sciences Inc | 2026-01-30 | Added / first present |
| LXEO | Lexeo Therapeutics Inc | 2026-01-30 | Added / first present |
| MGTX | MeiraGTx Holdings plc | 2026-01-30 | Added / first present |
| MNPR | Monopar Therapeutics Inc | 2026-01-30 | Added / first present |
| NKTR | Nektar Therapeutics | 2026-01-30 | Added / first present |
| OMER | Omeros Corp | 2026-01-30 | Added / first present |
| ORKA | Oruka Therapeutics Inc | 2026-01-30 | Added / first present |
| PGEN | Precigen Inc | 2026-01-30 | Added / first present |
| PRME | Prime Medicine Inc | 2026-01-30 | Added / first present |
| PROK | ProKidney Corp | 2026-01-30 | Added / first present |
| PVLA | Palvella Therapeutics Inc | 2026-01-30 | Added / first present |
| RIGL | Rigel Pharmaceuticals Inc | 2026-01-30 | Added / first present |
| RZLT | Rezolute Inc | 2026-01-30 | Added / first present |
| SEPN | Septerna Inc | 2026-01-30 | Added / first present |
| VSTM | Verastem Inc | 2026-01-30 | Added / first present |
| ZBIO | Zenas Biopharma Inc | 2026-01-30 | Added / first present |
| KALV | KalVista Pharmaceuticals Inc | 2025-07-31 | Added / first present |
| MTSR | Metsera Inc | 2025-07-31 | Added / first present |
| GHRS | GH Research PLC | 2025-07-31 | Added / first present |
| MAZE | Maze Therapeutics Inc | 2025-07-31 | Added / first present |
| SION | Sionna Therapeutics Inc | 2025-07-31 | Added / first present |
| UPB | Upstream Bio Inc | 2025-07-31 | Added / first present |
| MNMD | Mind Medicine MindMed Inc | 2025-01-31 | Added / first present |
| ATXS | Astria Therapeutics Inc | 2025-01-31 | Added / first present |
| THRD | Third Harmonic Bio Inc | 2025-01-31 | Added / first present |
| TRML | Tourmaline Bio Inc | 2025-01-31 | Added / first present |
| ALT | Altimmune Inc | 2025-01-31 | Added / first present |
| AVBP | ArriVent Biopharma Inc | 2025-01-31 | Added / first present |
| BCAX | Bicara Therapeutics Inc | 2025-01-31 | Added / first present |
| CAPR | Capricor Therapeutics Inc | 2025-01-31 | Added / first present |
| CRVS | Corvus Pharmaceuticals Inc | 2025-01-31 | Added / first present |
| EYPT | EyePoint Pharmaceuticals Inc | 2025-01-31 | Added / first present |
| GLUE | Monte Rosa Therapeutics Inc | 2025-01-31 | Added / first present |
| LENZ | LENZ Therapeutics Inc | 2025-01-31 | Added / first present |
| MBX | MBX Biosciences Inc | 2025-01-31 | Added / first present |
| MREO | Mereo Biopharma Group PLC | 2025-01-31 | Added / first present |
| OMER | Omeros Corp | 2025-01-31 | Added / first present |
| RAPP | Rapport Therapeutics Inc | 2025-01-31 | Added / first present |
| RNAC | Cartesian Therapeutics Inc | 2025-01-31 | Added / first present |
| TECX | Tectonic Therapeutic Inc | 2025-01-31 | Added / first present |
| TRDA | Entrada Therapeutics Inc | 2025-01-31 | Added / first present |
| XERS | Xeris Biopharma Holdings Inc | 2025-01-31 | Added / first present |
| APLT | Applied Therapeutics Inc | 2024-07-31 | Added / first present |
| CNTA | Centessa Pharmaceuticals PLC | 2024-07-31 | Added / first present |
| HLVX | HilleVax Inc | 2024-07-31 | Added / first present |
| AVTE | Aerovate Therapeutics Inc | 2024-07-31 | Added / first present |
| LBPH | Longboard Pharmaceuticals Inc | 2024-07-31 | Added / first present |
| CRGX | Cargo Therapeutics Inc | 2024-07-31 | Added / first present |
| ABUS | Arbutus Biopharma Corp | 2024-07-31 | Added / first present |
| ANNX | Annexon Inc | 2024-07-31 | Added / first present |
| ARQT | Arcutis Biotherapeutics Inc | 2024-07-31 | Added / first present |
| AUTL | Autolus Therapeutics PLC | 2024-07-31 | Added / first present |
| CATX | Perspective Therapeutics Inc | 2024-07-31 | Added / first present |
| CELC | Celcuity Inc | 2024-07-31 | Added / first present |
| CGON | CG oncology Inc | 2024-07-31 | Added / first present |
| DNTH | Dianthus Therapeutics Inc | 2024-07-31 | Added / first present |
| ELVN | Enliven Therapeutics Inc | 2024-07-31 | Added / first present |
| ERAS | Erasca Inc | 2024-07-31 | Added / first present |
| EWTX | Edgewise Therapeutics Inc | 2024-07-31 | Added / first present |
| FULC | Fulcrum Therapeutics Inc | 2024-07-31 | Added / first present |
| IMNM | Immunome Inc | 2024-07-31 | Added / first present |
| JANX | Janux Therapeutics Inc | 2024-07-31 | Added / first present |
| KYTX | Kyverna Therapeutics Inc | 2024-07-31 | Added / first present |
| LRMR | Larimar Therapeutics Inc | 2024-07-31 | Added / first present |
| NAMS | NEWAMSTERDAM PHARMA CO NV | 2024-07-31 | Added / first present |
| NGNE | Neurogene Inc | 2024-07-31 | Added / first present |
| NUVB | Nuvation Bio Inc | 2024-07-31 | Added / first present |
| PHVS | Pharvaris NV | 2024-07-31 | Added / first present |
| PRAX | Praxis Precision Medicines Inc | 2024-07-31 | Added / first present |
| PRME | Prime Medicine Inc | 2024-07-31 | Added / first present |
| SLN | Silence Therapeutics PLC | 2024-07-31 | Added / first present |
| STOK | Stoke Therapeutics Inc | 2024-07-31 | Added / first present |
| SVRA | Savara Inc | 2024-07-31 | Added / first present |
| TSHA | Taysha Gene Therapies Inc | 2024-07-31 | Added / first present |
| TYRA | Tyra Biosciences Inc | 2024-07-31 | Added / first present |
| WVE | WaVe Life Sciences Ltd | 2024-07-31 | Added / first present |
| ALPN | Alpine Immune Sciences Inc | 2024-01-31 | Added / first present |
| SLRN | ACELYRIN Inc | 2024-01-31 | Added / first present |
| RYZB | RayzeBio Inc | 2024-01-31 | Added / first present |
| SLNO | Soleno Therapeutics Inc | 2024-01-31 | Added / first present |
| APGE | Apogee Therapeutics Inc | 2024-01-31 | Added / first present |
| BEAM | Beam Therapeutics Inc | 2024-01-31 | Added / first present |
| BLTE | Belite Bio Inc | 2024-01-31 | Added / first present |
| CABA | Cabaletta Bio Inc | 2024-01-31 | Added / first present |
| MGNX | MacroGenics Inc | 2024-01-31 | Added / first present |
| NMRA | Neumora Therapeutics Inc | 2024-01-31 | Added / first present |
| OLMA | Olema Pharmaceuticals Inc | 2024-01-31 | Added / first present |
| ORIC | ORIC Pharmaceuticals Inc | 2024-01-31 | Added / first present |
| SANA | Sana Biotechnology Inc | 2024-01-31 | Added / first present |
| SRRK | Scholar Rock Holding Corp | 2024-01-31 | Added / first present |
| SYRE | Spyre Therapeutics Inc | 2024-01-31 | Added / first present |
| TNGX | Tango Therapeutics Inc | 2024-01-31 | Added / first present |
| VERA | Vera Therapeutics Inc | 2024-01-31 | Added / first present |
| CBAY | Cymabay Therapeutics Inc | 2023-07-31 | Added / first present |
| ETNB | 89bio Inc | 2023-07-31 | Added / first present |
| EXAI | Exscientia Plc | 2023-07-31 | Added / first present |
| TERN | Terns Pharmaceuticals Inc | 2023-07-31 | Added / first present |
| AMAM | Ambrx Biopharma Inc | 2023-07-31 | Added / first present |
| ALDX | Aldeyra Therapeutics Inc | 2023-07-31 | Added / first present |
| ARDX | Ardelyx Inc | 2023-07-31 | Added / first present |
| BMEA | Biomea Fusion Inc | 2023-07-31 | Added / first present |
| GPCR | Structure Therapeutics Inc | 2023-07-31 | Added / first present |
| IRON | Disc Medicine Inc | 2023-07-31 | Added / first present |
| LQDA | Liquidia Corp | 2023-07-31 | Added / first present |
| MLTX | MoonLake Immunotherapeutics | 2023-07-31 | Added / first present |
| MLYS | Mineralys Therapeutics Inc | 2023-07-31 | Added / first present |
| PHAT | Phathom Pharmaceuticals Inc | 2023-07-31 | Added / first present |
| VKTX | Viking Therapeutics Inc | 2023-07-31 | Added / first present |
| INKT | MiNK Therapeutics Inc | 2023-04-28 | Added / first present |
| ALLK | Allakos Inc | 2023-01-31 | Added / first present |
| ALVR | Allovir Inc | 2023-01-31 | Added / first present |
| VERV | Verve Therapeutics Inc | 2023-01-31 | Added / first present |
| ACLX | Arcellx Inc | 2023-01-31 | Added / first present |
| CINC | CinCor Pharma Inc | 2023-01-31 | Added / first present |
| NUVL | Nuvalent Inc | 2023-01-31 | Added / first present |
| ALT | Altimmune Inc | 2023-01-31 | Added / first present |
| BHVN | Biohaven Ltd | 2023-01-31 | Added / first present |
| COGT | Cogent Biosciences Inc | 2023-01-31 | Added / first present |
| DYN | Dyne Therapeutics Inc | 2023-01-31 | Added / first present |
| FDMT | 4D Molecular Therapeutics Inc | 2023-01-31 | Added / first present |
| IMTX | Immatics NV | 2023-01-31 | Added / first present |
| PLRX | Pliant Therapeutics Inc | 2023-01-31 | Added / first present |
| SCLX | Scilex Holding Co | 2023-01-31 | Added / first present |
| SMMT | Summit Therapeutics Inc | 2023-01-31 | Added / first present |
| VRDN | Viridian Therapeutics Inc | 2023-01-31 | Added / first present |
| IVVD | Invivyd Inc | 2022-10-31 | Added / first present |
| EQRX | EQRx Inc | 2022-07-29 | Added / first present |
| PNT | Point Biopharma Global Inc | 2022-07-29 | Added / first present |
| VTYX | Ventyx Biosciences Inc | 2022-07-29 | Added / first present |
| DSGN | Design Therapeutics Inc | 2022-07-29 | Added / first present |
| FHTX | Foghorn Therapeutics Inc | 2022-07-29 | Added / first present |
| LYEL | Lyell Immunopharma Inc | 2022-07-29 | Added / first present |
| PCVX | Vaxcyte Inc | 2022-07-29 | Added / first present |
| VBIV | VBI Vaccines Inc | 2022-01-31 | Added / first present |
| KZR | Kezar Life Sciences Inc | 2022-01-31 | Added / first present |
| ADGI | Adagio Therapeutics Inc | 2022-01-31 | Added / first present |
| IMGO | Imago Biosciences Inc | 2022-01-31 | Added / first present |
| GRPH | Graphite Bio Inc | 2022-01-31 | Added / first present |
| CNTA | Centessa Pharmaceuticals PLC | 2022-01-31 | Added / first present |
| DAWN | Day One Biopharmaceuticals Inc | 2022-01-31 | Added / first present |
| DICE | DICE Therapeutics Inc | 2022-01-31 | Added / first present |
| KNTE | Kinnate Biopharma Inc | 2022-01-31 | Added / first present |
| ABUS | Arbutus Biopharma Corp | 2022-01-31 | Added / first present |
| ACET | Adicet Bio Inc | 2022-01-31 | Added / first present |
| ATAI | ATAI Life Sciences NV | 2022-01-31 | Added / first present |
| AUTL | Autolus Therapeutics PLC | 2022-01-31 | Added / first present |
| CRBU | Caribou Biosciences Inc | 2022-01-31 | Added / first present |
| ERAS | Erasca Inc | 2022-01-31 | Added / first present |
| EWTX | Edgewise Therapeutics Inc | 2022-01-31 | Added / first present |
| FULC | Fulcrum Therapeutics Inc | 2022-01-31 | Added / first present |
| GHRS | GH Research PLC | 2022-01-31 | Added / first present |
| ROIV | Roivant Sciences Ltd | 2022-01-31 | Added / first present |
| RXRX | Recursion Pharmaceuticals Inc | 2022-01-31 | Added / first present |
| TCRT | Alaunos Therapeutics Inc | 2022-01-31 | Added / first present |
| TIL | Instil Bio Inc | 2022-01-31 | Added / first present |
| GRTS | Gritstone bio Inc | 2021-07-30 | Added / first present |
| MGTA | Magenta Therapeutics Inc | 2021-07-30 | Added / first present |
| KALV | KalVista Pharmaceuticals Inc | 2021-07-30 | Added / first present |
| CLVS | Clovis Oncology Inc | 2021-07-30 | Added / first present |
| KRON | Kronos Bio Inc | 2021-07-30 | Added / first present |
| PRTK | Paratek Pharmaceuticals Inc | 2021-07-30 | Added / first present |
| CMRX | Chimerix Inc | 2021-07-30 | Added / first present |
| CDAK | Codiak Biosciences Inc | 2021-07-30 | Added / first present |
| PSTX | Poseida Therapeutics Inc | 2021-07-30 | Added / first present |
| KDNY | Chinook Therapeutics Inc | 2021-07-30 | Added / first present |
| CERE | Cerevel Therapeutics Holdings | 2021-07-30 | Added / first present |
| SAVA | Cassava Sciences Inc | 2021-07-30 | Added / first present |
| MRUS | Merus NV | 2021-07-30 | Added / first present |
| GRCL | Gracell Biotechnologies Inc | 2021-07-30 | Added / first present |
| EVLO | Evelo Biosciences Inc | 2021-07-30 | Added / first present |
| SBTX | Silverback Therapeutics Inc | 2021-07-30 | Added / first present |
| GMTX | Gemini Therapeutics Inc | 2021-07-30 | Added / first present |
| ATHA | Athira Pharma Inc | 2021-07-30 | Added / first present |
| RXDX | Prometheus Biosciences Inc | 2021-07-30 | Added / first present |
| SESN | Sesen Bio Inc | 2021-07-30 | Added / first present |
| EPIX | Essa Pharma Inc | 2021-07-30 | Added / first present |
| ABCL | AbCellera Biologics Inc | 2021-07-30 | Added / first present |
| ACIU | AC Immune SA | 2021-07-30 | Added / first present |
| ALDX | Aldeyra Therapeutics Inc | 2021-07-30 | Added / first present |
| ALGS | Aligos Therapeutics Inc | 2021-07-30 | Added / first present |
| ANVS | Annovis Bio Inc | 2021-07-30 | Added / first present |
| AVIR | Atea Pharmaceuticals Inc | 2021-07-30 | Added / first present |
| BCAB | BioAtla Inc | 2021-07-30 | Added / first present |
| BCYC | Bicycle Therapeutics PLC | 2021-07-30 | Added / first present |
| BOLT | Bolt Biotherapeutics Inc | 2021-07-30 | Added / first present |
| CCCC | C4 Therapeutics Inc | 2021-07-30 | Added / first present |
| CGEM | Cullinan Oncology Inc | 2021-07-30 | Added / first present |
| CMPS | Compass Pathways Plc | 2021-07-30 | Added / first present |
| CRIS | Curis Inc | 2021-07-30 | Added / first present |
| FBRX | Forte Biosciences Inc | 2021-07-30 | Added / first present |
| FDMT | 4D Molecular Therapeutics Inc | 2021-07-30 | Added / first present |
| IDYA | Ideaya Biosciences Inc | 2021-07-30 | Added / first present |
| IMCR | Immunocore Holdings PLC | 2021-07-30 | Added / first present |
| KYMR | Kymera Therapeutics Inc | 2021-07-30 | Added / first present |
| LXRX | Lexicon Pharmaceuticals Inc | 2021-07-30 | Added / first present |
| NRIX | Nurix Therapeutics Inc | 2021-07-30 | Added / first present |
| NUVB | Nuvation Bio Inc | 2021-07-30 | Added / first present |
| OLMA | Olema Pharmaceuticals Inc | 2021-07-30 | Added / first present |
| PASG | Passage Bio Inc | 2021-07-30 | Added / first present |
| PMVP | PMV Pharmaceuticals Inc | 2021-07-30 | Added / first present |
| PRAX | Praxis Precision Medicines Inc | 2021-07-30 | Added / first present |
| PRLD | Prelude Therapeutics Inc | 2021-07-30 | Added / first present |
| STTK | Shattuck Labs Inc | 2021-07-30 | Added / first present |
| TARS | Tarsus Pharmaceuticals Inc | 2021-07-30 | Added / first present |
| TSHA | Taysha Gene Therapies Inc | 2021-07-30 | Added / first present |
| VOR | Vor BioPharma Inc | 2021-07-30 | Added / first present |
| IBRX | ImmunityBio Inc | 2021-04-30 | Added / first present |
| TCRR | TCR2 Therapeutics Inc | 2021-01-29 | Added / first present |
| UROV | Urovant Sciences Ltd | 2021-01-29 | Added / first present |
| NK | NantKwest Inc | 2021-01-29 | Added / first present |
| AFMD | Affimed NV | 2021-01-29 | Added / first present |
| MORF | Morphic Holding Inc | 2021-01-29 | Added / first present |
| ISEE | IVERIC bio Inc | 2021-01-29 | Added / first present |
| IMAB | I-Mab | 2021-01-29 | Added / first present |
| ETNB | 89bio Inc | 2021-01-29 | Added / first present |
| GMDA | Gamida Cell Ltd | 2021-01-29 | Added / first present |
| RPTX | Repare Therapeutics Inc | 2021-01-29 | Added / first present |
| CVAC | CureVac NV | 2021-01-29 | Added / first present |
| HGEN | Humanigen Inc | 2021-01-29 | Added / first present |
| AMTI | Applied Molecular Transport In | 2021-01-29 | Added / first present |
| ITOS | iTeos Therapeutics Inc | 2021-01-29 | Added / first present |
| FPRX | Five Prime Therapeutics Inc | 2021-01-29 | Added / first present |
| ALVR | Allovir Inc | 2021-01-29 | Added / first present |
| ALBO | Albireo Pharma Inc | 2021-01-29 | Added / first present |
| FMTX | Forma Therapeutics Holdings In | 2021-01-29 | Added / first present |
| ADCT | ADC Therapeutics SA | 2021-01-29 | Added / first present |
| ALXO | ALX Oncology Holdings Inc | 2021-01-29 | Added / first present |
| ANNX | Annexon Inc | 2021-01-29 | Added / first present |
| ARCT | Arcturus Therapeutics Holdings | 2021-01-29 | Added / first present |
| CDXS | Codexis Inc | 2021-01-29 | Added / first present |
| CLDX | Celldex Therapeutics Inc | 2021-01-29 | Added / first present |
| COGT | Cogent Biosciences Inc | 2021-01-29 | Added / first present |
| CRDF | Cardiff Oncology Inc | 2021-01-29 | Added / first present |
| IMTX | Immatics NV | 2021-01-29 | Added / first present |
| IMVT | Immunovant Inc | 2021-01-29 | Added / first present |
| INBX | Inhibrx Inc | 2021-01-29 | Added / first present |
| INO | Inovio Pharmaceuticals Inc | 2021-01-29 | Added / first present |
| KROS | Keros Therapeutics Inc | 2021-01-29 | Added / first present |
| LEGN | Legend Biotech Corp | 2021-01-29 | Added / first present |
| MCRB | Seres Therapeutics Inc | 2021-01-29 | Added / first present |
| NKTX | Nkarta Inc | 2021-01-29 | Added / first present |
| ORIC | ORIC Pharmaceuticals Inc | 2021-01-29 | Added / first present |
| PGEN | Precigen Inc | 2021-01-29 | Added / first present |
| PLRX | Pliant Therapeutics Inc | 2021-01-29 | Added / first present |
| REPL | Replimune Group Inc | 2021-01-29 | Added / first present |
| RLAY | Relay Therapeutics Inc | 2021-01-29 | Added / first present |
| RNA | Avidity Biosciences Inc | 2021-01-29 | Added / first present |
| SRRK | Scholar Rock Holding Corp | 2021-01-29 | Added / first present |
| STOK | Stoke Therapeutics Inc | 2021-01-29 | Added / first present |
| STRO | Sutro Biopharma Inc | 2021-01-29 | Added / first present |
| VXRT | Vaxart Inc | 2021-01-29 | Added / first present |
| ZNTL | Zentalis Pharmaceuticals Inc | 2021-01-29 | Added / first present |
| DGCXX | DREYFUS GOVERNMENT CASH MANAGEMENT | 2020-10-30 | Added / first present |
| VIE | Viela Bio Inc | 2020-07-31 | Added / first present |
| MTEM | Molecular Templates Inc | 2020-07-31 | Added / first present |
| RUBY | Rubius Therapeutics Inc | 2020-07-31 | Added / first present |
| DVAX | Dynavax Technologies Corp | 2020-07-31 | Added / first present |
| SYRS | Syros Pharmaceuticals Inc | 2020-07-31 | Added / first present |
| MRSN | Mersana Therapeutics Inc | 2020-07-31 | Added / first present |
| CALA | Calithera Biosciences Inc | 2020-07-31 | Added / first present |
| ADAP | Adaptimmune Therapeutics Plc | 2020-07-31 | Added / first present |
| FREQ | Frequency Therapeutics Inc | 2020-07-31 | Added / first present |
| RAPT | RAPT Therapeutics Inc | 2020-07-31 | Added / first present |
| PRVL | Prevail Therapeutics Inc | 2020-07-31 | Added / first present |
| KZR | Kezar Life Sciences Inc | 2020-07-31 | Added / first present |
| SELB | Selecta Biosciences Inc | 2020-07-31 | Added / first present |
| NGM | NGM Biopharmaceuticals Inc | 2020-07-31 | Added / first present |
| IGMS | IGM Biosciences Inc | 2020-07-31 | Added / first present |
| MEIP | MEI Pharma Inc | 2020-07-31 | Added / first present |
| OYST | Oyster Point Pharma Inc | 2020-07-31 | Added / first present |
| BCEL | Atreca Inc | 2020-07-31 | Added / first present |
| MRNS | Marinus Pharmaceuticals Inc | 2020-07-31 | Added / first present |
| APLT | Applied Therapeutics Inc | 2020-07-31 | Added / first present |
| HARP | Harpoon Therapeutics Inc | 2020-07-31 | Added / first present |
| 22UA | BIONTECH SE RIGHTS EX 08/14/20 | 2020-07-31 | Added / first present |
| APRE | Aprea Therapeutics Inc | 2020-07-31 | Added / first present |
| ARQT | Arcutis Biotherapeutics Inc | 2020-07-31 | Added / first present |
| BDTX | Black Diamond Therapeutics Inc | 2020-07-31 | Added / first present |
| BNTX | BioNTech SE | 2020-07-31 | Added / first present |
| BTAI | Bioxcel Therapeutics Inc | 2020-07-31 | Added / first present |
| CGEN | Compugen Ltd | 2020-07-31 | Added / first present |
| CRNX | Crinetics Pharmaceuticals Inc | 2020-07-31 | Added / first present |
| CUE | Cue Biopharma Inc | 2020-07-31 | Added / first present |
| EDIT | Editas Medicine Inc | 2020-07-31 | Added / first present |
| KNSA | Kiniksa Pharmaceuticals Ltd | 2020-07-31 | Added / first present |
| MIRM | Mirum Pharmaceuticals Inc | 2020-07-31 | Added / first present |
| NTLA | Intellia Therapeutics Inc | 2020-07-31 | Added / first present |
| NVAX | Novavax Inc | 2020-07-31 | Added / first present |
| OVID | Ovid therapeutics Inc | 2020-07-31 | Added / first present |
| PHAT | Phathom Pharmaceuticals Inc | 2020-07-31 | Added / first present |
| PRTA | Prothena Corp PLC | 2020-07-31 | Added / first present |
| PTGX | Protagonist Therapeutics Inc | 2020-07-31 | Added / first present |
| RCUS | Arcus Biosciences Inc | 2020-07-31 | Added / first present |
| RLMD | Relmada Therapeutics Inc | 2020-07-31 | Added / first present |
| RVMD | REVOLUTION Medicines Inc | 2020-07-31 | Added / first present |
| SNDX | Syndax Pharmaceuticals Inc | 2020-07-31 | Added / first present |
| VIR | Vir Biotechnology Inc | 2020-07-31 | Added / first present |
| VSTM | Verastem Inc | 2020-07-31 | Added / first present |
| XENE | Xenon Pharmaceuticals Inc | 2020-07-31 | Added / first present |
| TPTX | Turning Point Therapeutics Inc | 2020-01-31 | Added / first present |
| KRTX | Karuna Therapeutics Inc | 2020-01-31 | Added / first present |
| PRVB | Provention Bio Inc | 2020-01-31 | Added / first present |
| CRTX | Cortexyme Inc | 2020-01-31 | Added / first present |
| AKRO | Akero Therapeutics Inc | 2020-01-31 | Added / first present |
| SWTX | SpringWorks Therapeutics Inc | 2020-01-31 | Added / first present |
| YMAB | Y-mAbs Therapeutics Inc | 2020-01-31 | Added / first present |
| ODT | Odonate Therapeutics Inc | 2020-01-31 | Added / first present |
| KDMN | Kadmon Holdings Inc | 2020-01-31 | Added / first present |
| CNST | Constellation Pharmaceuticals | 2020-01-31 | Added / first present |
| TBIO | Translate Bio Inc | 2020-01-31 | Added / first present |
| ARDX | Ardelyx Inc | 2020-01-31 | Added / first present |
| BBIO | Bridgebio Pharma Inc | 2020-01-31 | Added / first present |
| CRSP | CRISPR Therapeutics AG | 2020-01-31 | Added / first present |
| CVM | CEL-SCI Corp | 2020-01-31 | Added / first present |
| DTIL | Precision BioSciences Inc | 2020-01-31 | Added / first present |
| FIXX | Homology Medicines Inc | 2020-01-31 | Added / first present |
| KOD | Kodiak Sciences Inc | 2020-01-31 | Added / first present |
| NXTC | NextCure Inc | 2020-01-31 | Added / first present |
| RIGL | Rigel Pharmaceuticals Inc | 2020-01-31 | Added / first present |
| XBIT | XBiotech Inc | 2020-01-31 | Added / first present |
| ZYME | Zymeworks Inc | 2020-01-31 | Added / first present |
Removals
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| RAPT | RAPT Therapeutics Inc | 2026-04-30 | Removed / first absent |
| VTYX | Ventyx Biosciences Inc | 2026-04-30 | Removed / first absent |
| KALV | KalVista Pharmaceuticals Inc | 2026-01-30 | Removed / first absent |
| MTSR | Metsera Inc | 2025-10-31 | Removed / first absent |
| MNMD | Mind Medicine MindMed Inc | 2026-01-30 | Removed / first absent |
| ATXS | Astria Therapeutics Inc | 2026-01-30 | Removed / first absent |
| THRD | Third Harmonic Bio Inc | 2025-07-31 | Removed / first absent |
| TRML | Tourmaline Bio Inc | 2025-10-31 | Removed / first absent |
| LENZ | LENZ Therapeutics Inc | 2026-01-30 | Removed / first absent |
| OMER | Omeros Corp | 2025-07-31 | Removed / first absent |
| RNAC | Cartesian Therapeutics Inc | 2026-01-30 | Removed / first absent |
| TRDA | Entrada Therapeutics Inc | 2026-01-30 | Removed / first absent |
| APLT | Applied Therapeutics Inc | 2025-01-31 | Removed / first absent |
| HLVX | HilleVax Inc | 2025-01-31 | Removed / first absent |
| AVTE | Aerovate Therapeutics Inc | 2025-01-31 | Removed / first absent |
| LBPH | Longboard Pharmaceuticals Inc | 2025-01-31 | Removed / first absent |
| CRGX | Cargo Therapeutics Inc | 2025-07-31 | Removed / first absent |
| ARQT | Arcutis Biotherapeutics Inc | 2026-01-30 | Removed / first absent |
| AUTL | Autolus Therapeutics PLC | 2026-01-30 | Removed / first absent |
| CATX | Perspective Therapeutics Inc | 2025-07-31 | Removed / first absent |
| FULC | Fulcrum Therapeutics Inc | 2025-01-31 | Removed / first absent |
| KYTX | Kyverna Therapeutics Inc | 2025-01-31 | Removed / first absent |
| LRMR | Larimar Therapeutics Inc | 2025-07-31 | Removed / first absent |
| NUVB | Nuvation Bio Inc | 2026-01-30 | Removed / first absent |
| PRME | Prime Medicine Inc | 2025-07-31 | Removed / first absent |
| SLN | Silence Therapeutics PLC | 2026-01-30 | Removed / first absent |
| ALPN | Alpine Immune Sciences Inc | 2024-07-31 | Removed / first absent |
| SLRN | ACELYRIN Inc | 2025-07-31 | Removed / first absent |
| RYZB | RayzeBio Inc | 2024-04-30 | Removed / first absent |
| CABA | Cabaletta Bio Inc | 2025-01-31 | Removed / first absent |
| MGNX | MacroGenics Inc | 2025-01-31 | Removed / first absent |
| NMRA | Neumora Therapeutics Inc | 2025-07-31 | Removed / first absent |
| CBAY | Cymabay Therapeutics Inc | 2024-04-30 | Removed / first absent |
| ETNB | 89bio Inc | 2025-10-31 | Removed / first absent |
| EXAI | Exscientia Plc | 2025-01-31 | Removed / first absent |
| AMAM | Ambrx Biopharma Inc | 2024-04-30 | Removed / first absent |
| ALDX | Aldeyra Therapeutics Inc | 2024-01-31 | Removed / first absent |
| ARDX | Ardelyx Inc | 2024-07-31 | Removed / first absent |
| BMEA | Biomea Fusion Inc | 2024-07-31 | Removed / first absent |
| PHAT | Phathom Pharmaceuticals Inc | 2024-07-31 | Removed / first absent |
| INKT | MiNK Therapeutics Inc | 2023-07-31 | Removed / first absent |
| ALLK | Allakos Inc | 2024-07-31 | Removed / first absent |
| ALVR | Allovir Inc | 2023-07-31 | Removed / first absent |
| VERV | Verve Therapeutics Inc | 2025-07-31 | Removed / first absent |
| ACLX | Arcellx Inc | 2026-04-30 | Removed / first absent |
| CINC | CinCor Pharma Inc | 2023-04-28 | Removed / first absent |
| ALT | Altimmune Inc | 2023-07-31 | Removed / first absent |
| FDMT | 4D Molecular Therapeutics Inc | 2025-07-31 | Removed / first absent |
| PLRX | Pliant Therapeutics Inc | 2025-07-31 | Removed / first absent |
| SCLX | Scilex Holding Co | 2025-07-31 | Removed / first absent |
| IVVD | Invivyd Inc | 2023-01-31 | Removed / first absent |
| EQRX | EQRx Inc | 2024-01-31 | Removed / first absent |
| PNT | Point Biopharma Global Inc | 2024-01-31 | Removed / first absent |
| VTYX | Ventyx Biosciences Inc | 2024-01-31 | Removed / first absent |
| DSGN | Design Therapeutics Inc | 2024-01-31 | Removed / first absent |
| FHTX | Foghorn Therapeutics Inc | 2023-01-31 | Removed / first absent |
| LYEL | Lyell Immunopharma Inc | 2025-01-31 | Removed / first absent |
| VBIV | VBI Vaccines Inc | 2022-07-29 | Removed / first absent |
| KZR | Kezar Life Sciences Inc | 2023-07-31 | Removed / first absent |
| ADGI | Adagio Therapeutics Inc | 2022-10-31 | Removed / first absent |
| IMGO | Imago Biosciences Inc | 2023-01-31 | Removed / first absent |
| GRPH | Graphite Bio Inc | 2022-07-29 | Removed / first absent |
| CNTA | Centessa Pharmaceuticals PLC | 2022-07-29 | Removed / first absent |
| DAWN | Day One Biopharmaceuticals Inc | 2024-07-31 | Removed / first absent |
| DICE | DICE Therapeutics Inc | 2023-10-31 | Removed / first absent |
| KNTE | Kinnate Biopharma Inc | 2022-07-29 | Removed / first absent |
| ABUS | Arbutus Biopharma Corp | 2024-01-31 | Removed / first absent |
| ACET | Adicet Bio Inc | 2023-07-31 | Removed / first absent |
| ATAI | ATAI Life Sciences NV | 2024-01-31 | Removed / first absent |
| AUTL | Autolus Therapeutics PLC | 2022-07-29 | Removed / first absent |
| CRBU | Caribou Biosciences Inc | 2024-07-31 | Removed / first absent |
| ERAS | Erasca Inc | 2024-01-31 | Removed / first absent |
| EWTX | Edgewise Therapeutics Inc | 2024-01-31 | Removed / first absent |
| FULC | Fulcrum Therapeutics Inc | 2022-07-29 | Removed / first absent |
| GHRS | GH Research PLC | 2023-01-31 | Removed / first absent |
| ROIV | Roivant Sciences Ltd | 2022-07-29 | Removed / first absent |
| TCRT | Alaunos Therapeutics Inc | 2022-07-29 | Removed / first absent |
| TIL | Instil Bio Inc | 2023-01-31 | Removed / first absent |
| GRTS | Gritstone bio Inc | 2022-07-29 | Removed / first absent |
| MGTA | Magenta Therapeutics Inc | 2022-01-31 | Removed / first absent |
| KALV | KalVista Pharmaceuticals Inc | 2022-07-29 | Removed / first absent |
| CLVS | Clovis Oncology Inc | 2022-07-29 | Removed / first absent |
| KRON | Kronos Bio Inc | 2022-07-29 | Removed / first absent |
| PRTK | Paratek Pharmaceuticals Inc | 2022-01-31 | Removed / first absent |
| CMRX | Chimerix Inc | 2022-07-29 | Removed / first absent |
| CDAK | Codiak Biosciences Inc | 2022-01-31 | Removed / first absent |
| PSTX | Poseida Therapeutics Inc | 2022-01-31 | Removed / first absent |
| KDNY | Chinook Therapeutics Inc | 2023-07-31 | Removed / first absent |
| CERE | Cerevel Therapeutics Holdings | 2024-01-31 | Removed / first absent |
| SAVA | Cassava Sciences Inc | 2025-01-31 | Removed / first absent |
| MRUS | Merus NV | 2025-10-31 | Removed / first absent |
| GRCL | Gracell Biotechnologies Inc | 2022-07-29 | Removed / first absent |
| EVLO | Evelo Biosciences Inc | 2022-07-29 | Removed / first absent |
| SBTX | Silverback Therapeutics Inc | 2022-01-31 | Removed / first absent |
| GMTX | Gemini Therapeutics Inc | 2022-01-31 | Removed / first absent |
| ATHA | Athira Pharma Inc | 2023-01-31 | Removed / first absent |
| RXDX | Prometheus Biosciences Inc | 2023-07-31 | Removed / first absent |
| SESN | Sesen Bio Inc | 2022-01-31 | Removed / first absent |
| EPIX | Essa Pharma Inc | 2022-07-29 | Removed / first absent |
| ACIU | AC Immune SA | 2022-07-29 | Removed / first absent |
| ALDX | Aldeyra Therapeutics Inc | 2022-07-29 | Removed / first absent |
| ALGS | Aligos Therapeutics Inc | 2022-07-29 | Removed / first absent |
| ANVS | Annovis Bio Inc | 2022-01-31 | Removed / first absent |
| AVIR | Atea Pharmaceuticals Inc | 2024-01-31 | Removed / first absent |
| BCAB | BioAtla Inc | 2022-07-29 | Removed / first absent |
| BOLT | Bolt Biotherapeutics Inc | 2022-01-31 | Removed / first absent |
| CCCC | C4 Therapeutics Inc | 2023-07-31 | Removed / first absent |
| CRIS | Curis Inc | 2022-07-29 | Removed / first absent |
| FBRX | Forte Biosciences Inc | 2022-01-31 | Removed / first absent |
| FDMT | 4D Molecular Therapeutics Inc | 2022-07-29 | Removed / first absent |
| IMCR | Immunocore Holdings PLC | 2022-07-29 | Removed / first absent |
| LXRX | Lexicon Pharmaceuticals Inc | 2022-07-29 | Removed / first absent |
| NUVB | Nuvation Bio Inc | 2023-07-31 | Removed / first absent |
| OLMA | Olema Pharmaceuticals Inc | 2022-07-29 | Removed / first absent |
| PASG | Passage Bio Inc | 2022-07-29 | Removed / first absent |
| PMVP | PMV Pharmaceuticals Inc | 2024-01-31 | Removed / first absent |
| PRAX | Praxis Precision Medicines Inc | 2022-07-29 | Removed / first absent |
| PRLD | Prelude Therapeutics Inc | 2023-01-31 | Removed / first absent |
| STTK | Shattuck Labs Inc | 2022-07-29 | Removed / first absent |
| TARS | Tarsus Pharmaceuticals Inc | 2022-01-31 | Removed / first absent |
| TSHA | Taysha Gene Therapies Inc | 2022-07-29 | Removed / first absent |
| VOR | Vor BioPharma Inc | 2022-07-29 | Removed / first absent |
| IBRX | ImmunityBio Inc | 2024-07-31 | Removed / first absent |
| TCRR | TCR2 Therapeutics Inc | 2022-01-31 | Removed / first absent |
| UROV | Urovant Sciences Ltd | 2021-04-30 | Removed / first absent |
| NK | NantKwest Inc | 2021-04-30 | Removed / first absent |
| AFMD | Affimed NV | 2023-07-31 | Removed / first absent |
| MORF | Morphic Holding Inc | 2024-10-31 | Removed / first absent |
| ISEE | IVERIC bio Inc | 2023-07-31 | Removed / first absent |
| IMAB | I-Mab | 2023-07-31 | Removed / first absent |
| ETNB | 89bio Inc | 2022-01-31 | Removed / first absent |
| GMDA | Gamida Cell Ltd | 2022-01-31 | Removed / first absent |
| RPTX | Repare Therapeutics Inc | 2023-07-31 | Removed / first absent |
| CVAC | CureVac NV | 2026-01-30 | Removed / first absent |
| HGEN | Humanigen Inc | 2022-07-29 | Removed / first absent |
| AMTI | Applied Molecular Transport In | 2022-07-29 | Removed / first absent |
| ITOS | iTeos Therapeutics Inc | 2025-10-31 | Removed / first absent |
| FPRX | Five Prime Therapeutics Inc | 2021-04-30 | Removed / first absent |
| ALVR | Allovir Inc | 2022-07-29 | Removed / first absent |
| ALBO | Albireo Pharma Inc | 2022-01-31 | Removed / first absent |
| FMTX | Forma Therapeutics Holdings In | 2022-07-29 | Removed / first absent |
| ADCT | ADC Therapeutics SA | 2021-07-30 | Removed / first absent |
| ALXO | ALX Oncology Holdings Inc | 2025-01-31 | Removed / first absent |
| ANNX | Annexon Inc | 2022-07-29 | Removed / first absent |
| ARCT | Arcturus Therapeutics Holdings | 2026-01-30 | Removed / first absent |
| CDXS | Codexis Inc | 2023-07-31 | Removed / first absent |
| COGT | Cogent Biosciences Inc | 2022-07-29 | Removed / first absent |
| CRDF | Cardiff Oncology Inc | 2022-01-31 | Removed / first absent |
| IMTX | Immatics NV | 2022-01-31 | Removed / first absent |
| INBX | Inhibrx Inc | 2024-07-31 | Removed / first absent |
| INO | Inovio Pharmaceuticals Inc | 2023-07-31 | Removed / first absent |
| LEGN | Legend Biotech Corp | 2022-07-29 | Removed / first absent |
| MCRB | Seres Therapeutics Inc | 2024-01-31 | Removed / first absent |
| NKTX | Nkarta Inc | 2023-07-31 | Removed / first absent |
| ORIC | ORIC Pharmaceuticals Inc | 2022-07-29 | Removed / first absent |
| PGEN | Precigen Inc | 2025-01-31 | Removed / first absent |
| PLRX | Pliant Therapeutics Inc | 2022-07-29 | Removed / first absent |
| RNA | Avidity Biosciences Inc | 2026-01-30 | Removed / first absent |
| SRRK | Scholar Rock Holding Corp | 2022-07-29 | Removed / first absent |
| STOK | Stoke Therapeutics Inc | 2024-01-31 | Removed / first absent |
| STRO | Sutro Biopharma Inc | 2022-07-29 | Removed / first absent |
| VXRT | Vaxart Inc | 2023-01-31 | Removed / first absent |
| ZNTL | Zentalis Pharmaceuticals Inc | 2025-07-31 | Removed / first absent |
| VIE | Viela Bio Inc | 2021-01-29 | Removed / first absent |
| MTEM | Molecular Templates Inc | 2022-01-31 | Removed / first absent |
| RUBY | Rubius Therapeutics Inc | 2022-07-29 | Removed / first absent |
| DVAX | Dynavax Technologies Corp | 2024-07-31 | Removed / first absent |
| SYRS | Syros Pharmaceuticals Inc | 2022-01-31 | Removed / first absent |
| MRSN | Mersana Therapeutics Inc | 2024-01-31 | Removed / first absent |
| CALA | Calithera Biosciences Inc | 2021-07-30 | Removed / first absent |
| ADAP | Adaptimmune Therapeutics Plc | 2022-07-29 | Removed / first absent |
| FREQ | Frequency Therapeutics Inc | 2022-01-31 | Removed / first absent |
| RAPT | RAPT Therapeutics Inc | 2024-07-31 | Removed / first absent |
| PRVL | Prevail Therapeutics Inc | 2021-01-29 | Removed / first absent |
| KZR | Kezar Life Sciences Inc | 2021-07-30 | Removed / first absent |
| SELB | Selecta Biosciences Inc | 2022-07-29 | Removed / first absent |
| NGM | NGM Biopharmaceuticals Inc | 2023-07-31 | Removed / first absent |
| IGMS | IGM Biosciences Inc | 2025-07-31 | Removed / first absent |
| MEIP | MEI Pharma Inc | 2022-07-29 | Removed / first absent |
| OYST | Oyster Point Pharma Inc | 2021-07-30 | Removed / first absent |
| BCEL | Atreca Inc | 2022-01-31 | Removed / first absent |
| MRNS | Marinus Pharmaceuticals Inc | 2022-07-29 | Removed / first absent |
| APLT | Applied Therapeutics Inc | 2022-01-31 | Removed / first absent |
| HARP | Harpoon Therapeutics Inc | 2022-01-31 | Removed / first absent |
| 22UA | BIONTECH SE RIGHTS EX 08/14/20 | 2020-10-30 | Removed / first absent |
| APRE | Aprea Therapeutics Inc | 2021-07-30 | Removed / first absent |
| ARQT | Arcutis Biotherapeutics Inc | 2024-01-31 | Removed / first absent |
| BDTX | Black Diamond Therapeutics Inc | 2022-01-31 | Removed / first absent |
| BNTX | BioNTech SE | 2021-01-29 | Removed / first absent |
| BTAI | Bioxcel Therapeutics Inc | 2024-01-31 | Removed / first absent |
| CGEN | Compugen Ltd | 2022-07-29 | Removed / first absent |
| CRNX | Crinetics Pharmaceuticals Inc | 2026-01-30 | Removed / first absent |
| CUE | Cue Biopharma Inc | 2022-07-29 | Removed / first absent |
| EDIT | Editas Medicine Inc | 2025-01-31 | Removed / first absent |
| KNSA | Kiniksa Pharmaceuticals Ltd | 2021-07-30 | Removed / first absent |
| MIRM | Mirum Pharmaceuticals Inc | 2022-07-29 | Removed / first absent |
| NVAX | Novavax Inc | 2024-07-31 | Removed / first absent |
| OVID | Ovid therapeutics Inc | 2021-01-29 | Removed / first absent |
| PHAT | Phathom Pharmaceuticals Inc | 2023-01-31 | Removed / first absent |
| RLMD | Relmada Therapeutics Inc | 2023-01-31 | Removed / first absent |
| SNDX | Syndax Pharmaceuticals Inc | 2026-01-30 | Removed / first absent |
| VSTM | Verastem Inc | 2022-07-29 | Removed / first absent |
| TPTX | Turning Point Therapeutics Inc | 2022-07-29 | Removed / first absent |
| KRTX | Karuna Therapeutics Inc | 2024-04-30 | Removed / first absent |
| PRVB | Provention Bio Inc | 2022-07-29 | Removed / first absent |
| CRTX | Cortexyme Inc | 2022-07-29 | Removed / first absent |
| AKRO | Akero Therapeutics Inc | 2025-10-31 | Removed / first absent |
| SWTX | SpringWorks Therapeutics Inc | 2024-01-31 | Removed / first absent |
| YMAB | Y-mAbs Therapeutics Inc | 2021-01-29 | Removed / first absent |
| ODT | Odonate Therapeutics Inc | 2021-07-30 | Removed / first absent |
| KDMN | Kadmon Holdings Inc | 2022-01-31 | Removed / first absent |
| CNST | Constellation Pharmaceuticals | 2021-07-30 | Removed / first absent |
| TBIO | Translate Bio Inc | 2021-10-29 | Removed / first absent |
| ARDX | Ardelyx Inc | 2022-01-31 | Removed / first absent |
| BBIO | Bridgebio Pharma Inc | 2022-07-29 | Removed / first absent |
| CRSP | CRISPR Therapeutics AG | 2024-01-31 | Removed / first absent |
| CVM | CEL-SCI Corp | 2022-07-29 | Removed / first absent |
| DTIL | Precision BioSciences Inc | 2022-07-29 | Removed / first absent |
| FIXX | Homology Medicines Inc | 2022-07-29 | Removed / first absent |
| KOD | Kodiak Sciences Inc | 2024-01-31 | Removed / first absent |
| NXTC | NextCure Inc | 2021-07-30 | Removed / first absent |
| RIGL | Rigel Pharmaceuticals Inc | 2021-07-30 | Removed / first absent |
| XBIT | XBiotech Inc | 2022-01-31 | Removed / first absent |
| DGCXX | DREYFUS GOVERNMENT CASH MANAGEMENT | 2020-04-30 | Removed / first absent |
| RETA | Reata Pharmaceuticals Inc | 2023-07-31 | Removed / first absent |
| ACHN | Achillion Pharmaceuticals Inc | 2020-01-31 | Removed / first absent |
| RARX | Ra Pharmaceuticals Inc | 2020-04-30 | Removed / first absent |
| DCPH | Deciphera Pharmaceuticals Inc | 2021-01-29 | Removed / first absent |
| ALLK | Allakos Inc | 2022-07-29 | Removed / first absent |
| EIDX | Eidos Therapeutics Inc | 2021-01-29 | Removed / first absent |
| AIMT | AIMMUNE THERAPEUTICS INC | 2020-01-31 | Removed / first absent |
| APLS | APELLIS PHARMACEUTICALS INC | 2021-07-30 | Removed / first absent |
| PGNX | Progenics Pharmaceuticals Inc | 2020-07-31 | Removed / first absent |
| IMMU | IMMUNOMEDICS INC | 2020-07-31 | Removed / first absent |
| MYOK | MyoKardia Inc | 2021-01-29 | Removed / first absent |
| ARQL | ArQule Inc | 2020-01-31 | Removed / first absent |
| IMGN | IMMUNOGEN INC | 2023-01-31 | Removed / first absent |
| XLRN | Acceleron Pharma Inc | 2020-01-31 | Removed / first absent |
| BGNE | BeiGene Ltd | 2020-01-31 | Removed / first absent |
| GTHX | G1 Therapeutics Inc | 2022-07-29 | Removed / first absent |
| DRNA | Dicerna Pharmaceuticals Inc | 2022-01-31 | Removed / first absent |
| TCDA | Tricida Inc | 2021-07-30 | Removed / first absent |
| THOR | Synthorx Inc | 2020-01-31 | Removed / first absent |
| CARA | Cara Therapeutics Inc | 2023-07-31 | Removed / first absent |
| AVRO | Avrobio Inc | 2022-01-31 | Removed / first absent |
| PRNB | Principia Biopharma Inc | 2020-10-30 | Removed / first absent |
| MRTX | MIRATI THERAPEUTICS INC | 2024-01-31 | Removed / first absent |
| EPZM | EPIZYME INC | 2020-07-31 | Removed / first absent |
| SGMO | Sangamo Therapeutics Inc | 2023-07-31 | Removed / first absent |
| FGEN | FIBROGEN INC | 2024-01-31 | Removed / first absent |
| GBT | Global Blood Therapeutics Inc | 2020-01-31 | Removed / first absent |
| ARNA | Arena Pharmaceuticals Inc | 2022-04-29 | Removed / first absent |
| AMRS | Amyris Inc | 2023-10-31 | Removed / first absent |
| ORTX | Orchard Therapeutics plc | 2022-01-31 | Removed / first absent |
| GRTS | Gritstone Oncology Inc | 2020-01-31 | Removed / first absent |
| ZIOP | ZIOPHARM Oncology Inc | 2022-01-31 | Removed / first absent |
| ESPR | Esperion Therapeutics Inc | 2020-07-31 | Removed / first absent |
| AKCA | Akcea Therapeutics Inc | 2020-01-31 | Removed / first absent |
| BPMC | BLUEPRINT MEDICINES CORP | 2020-07-31 | Removed / first absent |
| ITCI | Intra-Cellular Therapies Inc | 2021-01-29 | Removed / first absent |
| MGTA | Magenta Therapeutics Inc | 2020-01-31 | Removed / first absent |
| LJPC | LA JOLLA PHARMACEUTICAL CO | 2020-01-31 | Removed / first absent |
| CBAY | Cymabay Therapeutics Inc | 2020-01-31 | Removed / first absent |
| UBX | UNITY Biotechnology Inc | 2020-07-31 | Removed / first absent |
| BLUE | BLUEBIRD BIO INC | 2021-07-30 | Removed / first absent |
| ADVM | Adverum Biotechnologies Inc | 2022-01-31 | Removed / first absent |
| FTSV | Forty Seven Inc | 2020-04-30 | Removed / first absent |
| MYOV | Myovant Sciences Ltd | 2022-07-29 | Removed / first absent |
| ATNX | Athenex Inc | 2022-01-31 | Removed / first absent |
| KALV | KalVista Pharmaceuticals Inc | 2020-01-31 | Removed / first absent |
| SRNE | Sorrento Therapeutics Inc | 2023-04-28 | Removed / first absent |
| GLYC | GLYCOMIMETICS INC | 2020-07-31 | Removed / first absent |
| PHAS | PhaseBio Pharmaceuticals Inc | 2020-01-31 | Removed / first absent |
| ABEO | Abeona Therapeutics Inc | 2020-01-31 | Removed / first absent |
| AGEN | Agenus Inc | 2025-01-31 | Removed / first absent |
| AKBA | Akebia Therapeutics Inc | 2022-07-29 | Removed / first absent |
| ALEC | Alector Inc | 2025-01-31 | Removed / first absent |
| ARWR | Arrowhead Pharmaceuticals Inc | 2026-01-30 | Removed / first absent |
| ASMB | Assembly Biosciences Inc | 2021-01-29 | Removed / first absent |
| ASND | Ascendis Pharma A/S | 2022-01-31 | Removed / first absent |
| ATRA | Atara Biotherapeutics Inc | 2023-07-31 | Removed / first absent |
| AUTL | Autolus Therapeutics PLC | 2020-07-31 | Removed / first absent |
| AXSM | Axsome Therapeutics Inc | 2022-07-29 | Removed / first absent |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 2021-07-30 | Removed / first absent |
| BHVN | Biohaven Pharmaceutical Holdin | 2021-01-29 | Removed / first absent |
| BOLD | AUDENTES THERAPEUTICS INC | 2020-01-31 | Removed / first absent |
| CCXI | ChemoCentryx Inc | 2022-01-31 | Removed / first absent |
| CRBP | Corbus Pharmaceuticals Holding | 2021-01-29 | Removed / first absent |
| CTMX | CytomX Therapeutics Inc | 2022-07-29 | Removed / first absent |
| FATE | Fate Therapeutics Inc | 2024-01-31 | Removed / first absent |
| GERN | Geron Corp | 2024-07-31 | Removed / first absent |
| GOSS | Gossamer Bio Inc | 2023-01-31 | Removed / first absent |
| INSM | Insmed Inc | 2020-01-31 | Removed / first absent |
| IOVA | Iovance Biotherapeutics Inc | 2024-07-31 | Removed / first absent |
| KPTI | Karyopharm Therapeutics Inc | 2020-01-31 | Removed / first absent |
| KRYS | Krystal Biotech Inc | 2024-07-31 | Removed / first absent |
| KURA | Kura Oncology Inc | 2026-01-30 | Removed / first absent |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 2024-07-31 | Removed / first absent |
| MGNX | MacroGenics Inc | 2022-07-29 | Removed / first absent |
| MGTX | MeiraGTx Holdings plc | 2023-01-31 | Removed / first absent |
| MRNA | Moderna Inc | 2021-01-29 | Removed / first absent |
| PRQR | ProQR Therapeutics NV | 2020-01-31 | Removed / first absent |
| PRTA | Prothena Corp PLC | 2020-01-31 | Removed / first absent |
| PTCT | PTC Therapeutics Inc | 2020-01-31 | Removed / first absent |
| RYTM | Rhythm Pharmaceuticals Inc | 2022-07-29 | Removed / first absent |
| TGTX | TG Therapeutics Inc | 2024-07-31 | Removed / first absent |
| VKTX | Viking Therapeutics Inc | 2022-07-29 | Removed / first absent |
| VYGR | Voyager Therapeutics Inc | 2021-07-30 | Removed / first absent |
| WVE | WaVe Life Sciences Ltd | 2022-01-31 | Removed / first absent |