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ZYMEWORKS INC. (ZYME) Overview

ZYMEWORKS INC. (ZYME) Overview

  • 1 Apr 2026: Period ending 30 Jun 2026; Estimate (m); Actual -0.62; Beat / miss (m).
  • 1 Jan 2026: Period ending 31 Mar 2026; Estimate (m); Actual -0.59; Beat / miss (m).
  • 1 Jul 2025: Period ending 30 Sept 2025; Estimate (m); Actual -0.26; Beat / miss (m).
  • 1 Apr 2025: Period ending 30 Jun 2025; Estimate (m); Actual 0.03; Beat / miss (m).

Stock Price Chart

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Blue: Split-adjusted close · Orange: Cumulative dividend-reinvested close

$15.64$18.11$20.98$24.30$28.15$32.602025-11-062026-11-06$4.42$6.59$9.83$14.66$21.86$32.602021-11-082026-11-06$4.42$7.43$12.51$21.06$35.44$59.652017-04-282026-11-06$4.42$7.43$12.51$21.06$35.44$59.652017-04-282026-11-06$4.42$7.43$12.51$21.06$35.44$59.652017-04-282026-11-06

Logarithmic scale. Both lines share the same starting value for the selected range.

Last close
$29.63
Previous close
$27.20
Change
$2.43
Change (%)
8.93%
Close date
2026-11-06
Previous close date
2026-09-29
Open
(m)
Day high
(m)
Day low
(m)
Last session volume
(m)
Last session value
(m)
Currency
USD
Price basis
split-adjusted
Volume basis
(m)

Performance

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Cumulative total returns · 2026-09-29

YTD

ZYME
+3.30%
S&P 500
(m)

1 year

ZYME
+57.86%
S&P 500
(m)

3 years

ZYME
+329.02%
S&P 500
(m)

5 years

ZYME
-0.55%
S&P 500
(m)

Earnings trends

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Earnings per share

USD / share · As filed

30 Jun 2026 ○ Estimate (m) ● Actual -0.62

-0.70-0.47-0.24-0.020.2131 Mar 2025: estimate (m); actual -0.3031 Mar 2025(m)30 Jun 2025: estimate (m); actual 0.0330 Jun 2025(m)30 Sept 2025: estimate (m); actual -0.2630 Sept 2025(m)31 Mar 2026: estimate (m); actual -0.5931 Mar 2026(m)30 Jun 2026: estimate (m); actual -0.6230 Jun 2026(m)
Comparison details
Period startPeriod endingEstimateActualBeat / missReport date
1 Apr 202630 Jun 2026(m)-0.62(m)(m)
1 Jan 202631 Mar 2026(m)-0.59(m)(m)
1 Jul 202530 Sept 2025(m)-0.26(m)(m)
1 Apr 202530 Jun 2025(m)0.03(m)(m)
1 Jan 202531 Mar 2025(m)-0.30(m)(m)

31 Dec 2025 ○ Estimate (m) ● Actual -1.08

-4.69-3.00-1.310.392.0831 Dec 2021: estimate (m); actual -4.6131 Dec 2021(m)31 Dec 2022: estimate (m); actual 1.9031 Dec 2022(m)31 Dec 2023: estimate (m); actual -1.7231 Dec 2023(m)31 Dec 2024: estimate (m); actual -1.6231 Dec 2024(m)31 Dec 2025: estimate (m); actual -1.0831 Dec 2025(m)
Comparison details
Period startPeriod endingEstimateActualBeat / missReport date
1 Jan 202531 Dec 2025(m)-1.08(m)(m)
1 Jan 202431 Dec 2024(m)-1.62(m)(m)
1 Jan 202331 Dec 2023(m)-1.72(m)(m)
1 Jan 202231 Dec 2022(m)1.90(m)(m)
1 Jan 202131 Dec 2021(m)-4.61(m)(m)

Revenue vs. Earnings

USD

30 Jun 2026 ■ Revenue 4.59M ■ Earnings -45.02M — Profit margin -980.81%

-53.73M-1835.0%-23.71M-1246.6%6.31M-658.3%36.33M-70.0%30 Sept 2025: revenue 27.61M; earnings -19.60M; profit margin -70.99%30 Sept 202531 Dec 2025: revenue 2.52M*; earnings -41.21M*; profit margin -1638.53%*; Revenue: Annual amount − nine-month amount; Earnings: Annual amount − nine-month amount; period 2025-10-01 to 2025-12-31; USD.31 Dec 202531 Mar 2026: revenue 2.41M; earnings -44.16M; profit margin -1833.97%31 Mar 202630 Jun 2026: revenue 4.59M; earnings -45.02M; profit margin -980.81%30 Jun 2026

31 Dec 2025 ■ Revenue 105.97M ■ Earnings -81.13M — Profit margin -76.56%

-186.92M-161.8%34.29M-97.5%255.50M-33.2%476.70M31.1%31 Dec 2022: revenue 412.48M; earnings 124.34M; profit margin 30.14%31 Dec 202231 Dec 2023: revenue 76.01M; earnings -118.67M; profit margin -156.13%31 Dec 202331 Dec 2024: revenue 76.30M; earnings -122.69M; profit margin -160.80%31 Dec 202431 Dec 2025: revenue 105.97M; earnings -81.13M; profit margin -76.56%31 Dec 2025

Analyst insights

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RatingsBuyHoldSellOther ratingsLast CloseAverage TargetUpsideHigh TargetLow Target
(m)(m)(m)(m)(m)$29.63(m)(m)(m)(m)
Past 12 Months12 Month ForecastLast Close$29.63High(m)Average(m)Low(m)2025-11-062026-11-06

Recent news

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(m)

YouTube videos mentioning ZYME

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(m)

Statistics

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Retained observations as of 2026-11-11; financial period ending 30 Jun 2026.

Forward P/E
(m)
PEG ratio · 5-year expected
(m)
Shares held by insiders
(m)
Insider transactions · change (%)
(m)
Shares held by institutions
(m)
Institutional transactions · change (%)
(m)
Diluted EPS · 12 month
(m)
EPS estimate · next quarter
(m)
EPS estimate · next year
(m)
EPS growth · current annual estimate
(m)
EPS growth · next annual estimate
(m)
EPS growth · next 5 years expected
(m)
EPS growth · past 3 years annualized
(m)
EPS growth · past 5 years annualized
(m)
EPS change · 12 months vs prior year
(m)
EPS change · latest quarter vs previous quarter
(m)
Latest earnings report date
(m)
EPS surprise · latest reported quarter
(m)
Net income · 12 month
$-149.99M
Profit margin
-404.00%
Return on assets · 12 month
-37.25%
Named executive and board stock awards · latest fiscal year
(m)
Index membership
(m)
Employees
264.00
IPO date
(m)
Options available
(m)
Shortable
(m)
Analyst recommendation
(m)
Analyst target price
(m)
Price volatility · week
(m)
Price volatility · month
(m)
Average true range · 14 sessions
(m)
Relative strength index · 14 sessions
(m)
Relative volume
(m)
Average daily volume
764.43K
Latest session volume
(m)
Last session value
(m)
30 days ago session value
(m)
1 year ago session value
(m)
Number of trades
(m)
Total return · week
-1.32%*
Total return · month
-3.78%*
Total return · quarter
12.86%*
Total return · half year
12.49%*
Total return · year to date
3.30%*
Total return · 1 year
57.86%*
Total return · 3 years
329.02%*
Total return · 5 years
-0.55%*
Market cap
(m)
Book value per share · latest quarter
(m)
Price / cash · latest quarter
(m)
Enterprise value
(m)
Enterprise value / revenue
(m)
Enterprise value / EBITDA
(m)
Dividend · 12 months per share
(m)
Dividend ex-date
(m)
Next dividend ex-date
(m)
Next dividend amount per share
(m)
Dividend growth · 3 years annualized
(m)
Dividend growth · 5 years annualized
(m)
Revenue · 12 month
$37.13M
Revenue growth · past 3 years annualized
(m)
Revenue growth · past 5 years annualized
(m)
Revenue change · 12 months vs prior year
(m)
Revenue change · latest quarter vs previous quarter
(m)
Revenue surprise · latest reported quarter
(m)
Levered free cash flow · 12 month
(m)
Debt / equity · latest quarter
(m)
Long-term debt / equity · latest quarter
(m)
Return on equity · 12 month
(m)
Return on invested capital · 12 months
(m)
Previous close
(m)
Latest closing price
(m)
Latest session change (%)
(m)
52-week high
(m)
52-week low
(m)
Price vs 20-session moving average
(m)
Price vs 50-session moving average
(m)
Price vs 200-session moving average
(m)
Float shares
(m)
Short float (%)
(m)
Short ratio (days to cover)
(m)
Short interest (shares)
(m)

Five-year projected P/E and P/S repeat the preceding five-year EPS and revenue CAGR, holding current price and market cap constant. Hover a calculated row for its formula. Net assets = assets − debt − payables − deferred revenue − obligations due within 1 year − obligations due after 1 year.

Holders breakdown

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BreakdownOwnership
(m)Shares held by all insiders
(m)Shares held by institutions
(m)Float held by institutions
(m)Institutions holding shares

Other holders

(m)

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Insider holders

(m)

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Top institutional holders

(m)

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Top mutual fund holders

(m)

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ZYMEWORKS INC. Overview

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(m)

(m)

SEC CIK
1937653
Industry (SIC)
2834 Pharmaceutical Preparations
Country of operation
United States
Business address
108 PATRIOT DRIVE, SUITE A, MIDDLETOWN, Delaware, 19709, United States
Fiscal year end
1231
Phone
302-274-8744

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