Companies included in XBI
This is XBI's own dated portfolio constitution. Share counts are the calculation basis for constituent revenue and earnings analytics; rounded weights are reference values only. This page shows positions 1–100 of 158.
| Ticker | Issuer | Shares owned | Unit | Reported weight |
|---|---|---|---|---|
| State Street Global Advisors | State Street Global Advisors | 595,460,501 | NS | 8.009477% |
| Apellis Pharmaceuticals Inc | Apellis Pharmaceuticals Inc | 3,390,454 | NS | 1.834675% |
| ALKS | Alkermes PLC | 3,050,830 | NS | 1.451047% |
| MDGL | Madrigal Pharmaceuticals Inc | 196,408 | NS | 1.382936% |
| TGTX | TG Therapeutics Inc | 3,020,301 | NS | 1.349588% |
| INSM | Insmed Inc | 607,845 | NS | 1.336949% |
| SRRK | Scholar Rock Holding Corp | 1,961,965 | NS | 1.297342% |
| APGE | Apogee Therapeutics Inc | 1,134,394 | NS | 1.284318% |
| PTGX | Protagonist Therapeutics Inc | 878,071 | NS | 1.244863% |
| SMMT | Summit Therapeutics Inc | 4,866,448 | NS | 1.241085% |
| UTHR | United Therapeutics Corp | 155,530 | NS | 1.240525% |
| PRAX | Praxis Precision Medicines Inc | 285,252 | NS | 1.236209% |
| ARWR | Arrowhead Pharmaceuticals Inc | 1,458,207 | NS | 1.22981% |
| COGT | Cogent Biosciences Inc | 2,348,101 | NS | 1.215671% |
| BBIO | Bridgebio Pharma Inc | 1,186,816 | NS | 1.185467% |
| PTCT | PTC Therapeutics Inc | 1,290,071 | NS | 1.182233% |
| CYTK | Cytokinetics Inc | 1,331,453 | NS | 1.180398% |
| ALNY | Alnylam Pharmaceuticals Inc | 264,406 | NS | 1.176738% |
| EXEL | Exelixis Inc | 2,029,215 | NS | 1.170672% |
| Nuvalent Inc | Nuvalent Inc | 846,768 | NS | 1.166884% |
| KYMR | Kymera Therapeutics Inc | 1,039,280 | NS | 1.164332% |
| CGON | CG oncology Inc | 1,276,920 | NS | 1.162453% |
| NTRA | Natera Inc | 430,933 | NS | 1.159229% |
| NBIX | Neurocrine Biosciences Inc | 654,044 | NS | 1.15898% |
| TWST | Twist Bioscience Corp | 1,808,036 | NS | 1.155672% |
| KRYS | Krystal Biotech Inc | 332,277 | NS | 1.154541% |
| PCVX | Vaxcyte Inc | 1,472,715 | NS | 1.151121% |
| MIRM | Mirum Pharmaceuticals Inc | 923,473 | NS | 1.147502% |
| Amicus Therapeutics Inc | Amicus Therapeutics Inc | 5,895,670 | NS | 1.146708% |
| IONS | Ionis Pharmaceuticals Inc | 1,132,906 | NS | 1.144267% |
| TVTX | Travere Therapeutics Inc | 2,863,192 | NS | 1.144206% |
| Arcellx Inc | Arcellx Inc | 740,785 | NS | 1.144092% |
| REGN | Regeneron Pharmaceuticals Inc | 109,400 | NS | 1.136961% |
| INCY | Incyte Corp | 895,013 | NS | 1.133085% |
| CELC | Celcuity Inc | 731,925 | NS | 1.123714% |
| Revolution Medicines Inc | Revolution Medicines Inc | 850,768 | NS | 1.112889% |
| HALO | Halozyme Therapeutics Inc | 1,274,489 | NS | 1.107953% |
| RYTM | Rhythm Pharmaceuticals Inc | 941,162 | NS | 1.100994% |
| BIIB | Biogen Inc | 444,855 | NS | 1.096991% |
| ARQT | Arcutis Biotherapeutics Inc | 3,437,805 | NS | 1.089451% |
| ABBV | AbbVie Inc | 372,103 | NS | 1.088563% |
| GILD | Gilead Sciences Inc | 580,264 | NS | 1.087793% |
| CRSP | CRISPR Therapeutics AG | 1,696,801 | NS | 1.085714% |
| BMRN | BioMarin Pharmaceutical Inc | 1,404,601 | NS | 1.067274% |
| ROIV | Roivant Sciences Ltd | 2,864,237 | NS | 1.067186% |
| AMGN | Amgen Inc | 224,546 | NS | 1.062708% |
| IBRX | ImmunityBio Inc | 10,244,025 | NS | 1.056859% |
| BEAM | Beam Therapeutics Inc | 3,248,626 | NS | 1.041298% |
| VKTX | Viking Therapeutics Inc | 2,369,189 | NS | 1.036975% |
| VERA | Vera Therapeutics Inc | 1,912,054 | NS | 1.034669% |
| MRNA | Moderna Inc | 1,513,720 | NS | 1.034333% |
| VRTX | Vertex Pharmaceuticals Inc | 172,078 | NS | 1.033563% |
| ERAS | Erasca Inc | 4,733,094 | NS | 1.030089% |
| ACAD | ACADIA Pharmaceuticals Inc | 3,412,655 | NS | 1.021807% |
| SRPT | Sarepta Therapeutics Inc | 3,057,030 | NS | 0.894767% |
| AGIO | Agios Pharmaceuticals Inc | 1,930,324 | NS | 0.878382% |
| RARE | Ultragenyx Pharmaceutical Inc | 3,107,837 | NS | 0.875777% |
| IRON | Disc Medicine Inc | 1,012,048 | NS | 0.870412% |
| IMNM | Immunome Inc | 2,934,802 | NS | 0.863334% |
| IMVT | Immunovant Inc | 2,566,528 | NS | 0.857529% |
| BCRX | BioCryst Pharmaceuticals Inc | 6,655,054 | NS | 0.852197% |
| VCYT | Veracyte Inc | 1,957,681 | NS | 0.848172% |
| DYN | Dyne Therapeutics Inc | 3,437,524 | NS | 0.838291% |
| Catalyst Pharmaceuticals Inc | Catalyst Pharmaceuticals Inc | 2,268,292 | NS | 0.755441% |
| SNDX | Syndax Pharmaceuticals Inc | 2,343,191 | NS | 0.736261% |
| DNLI | Denali Therapeutics Inc | 2,830,854 | NS | 0.731088% |
| IDYA | Ideaya Biosciences Inc | 1,628,726 | NS | 0.729969% |
| SYRE | Spyre Therapeutics Inc | 1,069,556 | NS | 0.725654% |
| GRAL | GRAIL Inc | 1,041,295 | NS | 0.723848% |
| VRDN | Viridian Therapeutics Inc | 2,667,007 | NS | 0.701688% |
| RXRX | Recursion Pharmaceuticals Inc | 16,732,511 | NS | 0.690957% |
| KOD | Kodiak Sciences Inc | 1,344,151 | NS | 0.689211% |
| Soleno Therapeutics Inc | Soleno Therapeutics Inc | 1,496,078 | NS | 0.673738% |
| DNTH | Dianthus Therapeutics Inc | 586,673 | NS | 0.662236% |
| NTLA | Intellia Therapeutics Inc | 3,753,333 | NS | 0.647227% |
| MLYS | Mineralys Therapeutics Inc | 1,773,248 | NS | 0.646145% |
| RCUS | Arcus Biosciences Inc | 2,163,363 | NS | 0.628542% |
| ARDX | Ardelyx Inc | 7,664,448 | NS | 0.617531% |
| ADMA | ADMA Biologics Inc | 4,916,092 | NS | 0.595794% |
| NRIX | Nurix Therapeutics Inc | 2,809,877 | NS | 0.585828% |
| TNGX | Tango Therapeutics Inc | 1,972,571 | NS | 0.555067% |
| CLDX | Celldex Therapeutics Inc | 1,222,480 | NS | 0.521586% |
| NVAX | Novavax Inc | 4,667,715 | NS | 0.511069% |
| ORKA | Oruka Therapeutics Inc | 761,033 | NS | 0.502104% |
| OLMA | Olema Pharmaceuticals Inc | 2,471,879 | NS | 0.495742% |
| STOK | Stoke Therapeutics Inc | 1,125,672 | NS | 0.493001% |
| VCEL | Vericel Corp | 1,116,252 | NS | 0.483019% |
| CAPR | Capricor Therapeutics Inc | 1,171,894 | NS | 0.479196% |
| PVLA | Palvella Therapeutics Inc | 274,232 | NS | 0.459792% |
| BHVN | Biohaven Ltd | 3,844,682 | NS | 0.437504% |
| GLUE | Monte Rosa Therapeutics Inc | 1,966,731 | NS | 0.435173% |
| CRVS | Corvus Pharmaceuticals Inc | 2,116,858 | NS | 0.416569% |
| IOVA | Iovance Biotherapeutics Inc | 8,139,873 | NS | 0.384305% |
| ANAB | AnaptysBio Inc | 512,175 | NS | 0.382076% |
| RLAY | Relay Therapeutics Inc | 2,831,639 | NS | 0.378976% |
| QURE | uniQure NV | 1,697,402 | NS | 0.373296% |
| ORIC | ORIC Pharmaceuticals Inc | 2,171,512 | NS | 0.370075% |
| MNKD | MannKind Corp | 10,933,657 | NS | 0.360315% |
| CDNA | CareDx Inc | 1,480,419 | NS | 0.345689% |
| TSHA | Taysha Gene Therapies Inc | 5,638,911 | NS | 0.339042% |
SEC N-PORT snapshot as of .