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AGIOS PHARMACEUTICALS, INC. (AGIO) Overview

AGIOS PHARMACEUTICALS, INC. (AGIO) Overview

  • 1 Apr 2026: Period ending 30 Jun 2026; Estimate (m); Actual -1.69; Beat / miss (m).
  • 1 Jan 2026: Period ending 31 Mar 2026; Estimate (m); Actual -1.69; Beat / miss (m).
  • 1 Jul 2025: Period ending 30 Sept 2025; Estimate (m); Actual -1.78; Beat / miss (m).
  • 1 Apr 2025: Period ending 30 Jun 2025; Estimate (m); Actual -1.93; Beat / miss (m).

Stock Price Chart

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Blue: Split-adjusted close · Orange: Cumulative dividend-reinvested close

$21.22$24.96$29.36$34.53$40.61$47.762025-11-062026-11-06$16.21$21.38$28.20$37.20$49.07$64.722021-11-082026-11-06$16.21$23.53$34.16$49.59$72.00$104.532016-11-072026-11-06$15.26$23.83$37.21$58.12$90.77$141.762013-07-242026-11-06$15.26$23.83$37.21$58.12$90.77$141.762013-07-242026-11-06

Logarithmic scale. Both lines share the same starting value for the selected range.

Last close
$29.38
Previous close
$33.30
Change
-$3.92
Change (%)
-11.77%
Close date
2026-11-06
Previous close date
2026-09-29
Open
(m)
Day high
(m)
Day low
(m)
Last session volume
(m)
Last session value
(m)
Currency
USD
Price basis
split-adjusted
Volume basis
(m)

Performance

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Cumulative total returns · 2026-09-29

YTD

AGIO
+22.34%
S&P 500
(m)

1 year

AGIO
-15.20%
S&P 500
(m)

3 years

AGIO
+34.55%
S&P 500
(m)

5 years

AGIO
-27.94%
S&P 500
(m)

Earnings trends

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Earnings per share

USD / share · As filed

30 Jun 2026 ○ Estimate (m) ● Actual -1.69

-2.01-1.85-1.69-1.53-1.3731 Mar 2025: estimate (m); actual -1.5531 Mar 2025(m)30 Jun 2025: estimate (m); actual -1.9330 Jun 2025(m)30 Sept 2025: estimate (m); actual -1.7830 Sept 2025(m)31 Mar 2026: estimate (m); actual -1.6931 Mar 2026(m)30 Jun 2026: estimate (m); actual -1.6930 Jun 2026(m)
Comparison details
Period startPeriod endingEstimateActualBeat / missReport date
1 Apr 202630 Jun 2026(m)-1.69(m)(m)
1 Jan 202631 Mar 2026(m)-1.69(m)(m)
1 Jul 202530 Sept 2025(m)-1.78(m)(m)
1 Apr 202530 Jun 2025(m)-1.93(m)(m)
1 Jan 202531 Mar 2025(m)-1.55(m)(m)

31 Dec 2025 ○ Estimate (m) ● Actual -7.12

-7.201.289.7718.2526.7331 Dec 2021: estimate (m); actual 26.5531 Dec 2021(m)31 Dec 2022: estimate (m); actual -4.2331 Dec 2022(m)31 Dec 2023: estimate (m); actual -6.3331 Dec 2023(m)31 Dec 2024: estimate (m); actual 11.6431 Dec 2024(m)31 Dec 2025: estimate (m); actual -7.1231 Dec 2025(m)
Comparison details
Period startPeriod endingEstimateActualBeat / missReport date
1 Jan 202531 Dec 2025(m)-7.12(m)(m)
1 Jan 202431 Dec 2024(m)11.64(m)(m)
1 Jan 202331 Dec 2023(m)-6.33(m)(m)
1 Jan 202231 Dec 2022(m)-4.23(m)(m)
1 Jan 202131 Dec 2021(m)26.55(m)(m)

Revenue vs. Earnings

USD

30 Jun 2026 ■ Revenue 44.74M ■ Earnings -100.70M — Profit margin -225.06%

-126.62M-804.1%-63.38M-610.7%-0.14M-417.4%63.11M-224.1%30 Sept 2025: revenue 12.88M; earnings -103.43M; profit margin -803.05%30 Sept 202531 Dec 2025: revenue 19.97M*; earnings -108.26M*; profit margin -542.18%*; Revenue: Annual amount − nine-month amount; Earnings: Annual amount − nine-month amount; period 2025-10-01 to 2025-12-31; USD.31 Dec 202531 Mar 2026: revenue 20.75M; earnings -99.11M; profit margin -477.74%31 Mar 202630 Jun 2026: revenue 44.74M; earnings -100.70M; profit margin -225.06%30 Jun 2026

31 Dec 2025 ■ Revenue 54.03M ■ Earnings -413.00M — Profit margin -764.42%

-543.44M-1630.2%-94.15M-470.9%355.15M688.4%804.44M1847.7%31 Dec 2022: revenue 14.24M; earnings -232.00M; profit margin -1629.21%31 Dec 202231 Dec 2023: revenue 26.82M; earnings -352.00M; profit margin -1312.31%31 Dec 202331 Dec 2024: revenue 36.50M; earnings 674.00M; profit margin 1846.68%31 Dec 202431 Dec 2025: revenue 54.03M; earnings -413.00M; profit margin -764.42%31 Dec 2025

Analyst insights

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RatingsBuyHoldSellOther ratingsLast CloseAverage TargetUpsideHigh TargetLow Target
(m)(m)(m)(m)(m)$29.38(m)(m)(m)(m)
Past 12 Months12 Month ForecastLast Close$29.38High(m)Average(m)Low(m)2025-11-062026-11-06

Recent news

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(m)

YouTube videos mentioning AGIO

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(m)

Statistics

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Retained observations as of 2026-11-11; financial period ending 30 Jun 2026.

Forward P/E
(m)
PEG ratio · 5-year expected
(m)
Shares held by insiders
(m)
Insider transactions · change (%)
(m)
Shares held by institutions
(m)
Institutional transactions · change (%)
(m)
Diluted EPS · 12 month
(m)
EPS estimate · next quarter
(m)
EPS estimate · next year
(m)
EPS growth · current annual estimate
(m)
EPS growth · next annual estimate
(m)
EPS growth · next 5 years expected
(m)
EPS growth · past 3 years annualized
(m)
EPS growth · past 5 years annualized
(m)
EPS change · 12 months vs prior year
(m)
EPS change · latest quarter vs previous quarter
(m)
Latest earnings report date
(m)
EPS surprise · latest reported quarter
(m)
Net income · 12 month
$-411.50M
Profit margin
-418.46%
Return on assets · 12 month
-31.90%
Named executive and board stock awards · latest fiscal year
(m)
Index membership
(m)
Employees
539.00
IPO date
(m)
Options available
(m)
Shortable
(m)
Analyst recommendation
(m)
Analyst target price
(m)
Price volatility · week
(m)
Price volatility · month
(m)
Average true range · 14 sessions
(m)
Relative strength index · 14 sessions
(m)
Relative volume
(m)
Average daily volume
937.21K
Latest session volume
(m)
Last session value
(m)
30 days ago session value
(m)
1 year ago session value
(m)
Number of trades
(m)
Total return · week
-4.78%*
Total return · month
-0.06%*
Total return · quarter
-12.46%*
Total return · half year
13.15%*
Total return · year to date
22.34%*
Total return · 1 year
-15.20%*
Total return · 3 years
34.55%*
Total return · 5 years
-27.94%*
Market cap
(m)
Book value per share · latest quarter
(m)
Price / cash · latest quarter
(m)
Enterprise value
(m)
Enterprise value / revenue
(m)
Enterprise value / EBITDA
(m)
Dividend · 12 months per share
(m)
Dividend ex-date
(m)
Next dividend ex-date
(m)
Next dividend amount per share
(m)
Dividend growth · 3 years annualized
(m)
Dividend growth · 5 years annualized
(m)
Revenue · 12 month
$98.34M
Revenue growth · past 3 years annualized
(m)
Revenue growth · past 5 years annualized
(m)
Revenue change · 12 months vs prior year
(m)
Revenue change · latest quarter vs previous quarter
(m)
Revenue surprise · latest reported quarter
(m)
Levered free cash flow · 12 month
(m)
Debt / equity · latest quarter
(m)
Long-term debt / equity · latest quarter
(m)
Return on equity · 12 month
(m)
Return on invested capital · 12 months
(m)
Previous close
(m)
Latest closing price
(m)
Latest session change (%)
(m)
52-week high
(m)
52-week low
(m)
Price vs 20-session moving average
(m)
Price vs 50-session moving average
(m)
Price vs 200-session moving average
(m)
Float shares
(m)
Short float (%)
(m)
Short ratio (days to cover)
(m)
Short interest (shares)
(m)

Five-year projected P/E and P/S repeat the preceding five-year EPS and revenue CAGR, holding current price and market cap constant. Hover a calculated row for its formula. Net assets = assets − debt − payables − deferred revenue − obligations due within 1 year − obligations due after 1 year.

Holders breakdown

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BreakdownOwnership
(m)Shares held by all insiders
(m)Shares held by institutions
(m)Float held by institutions
(m)Institutions holding shares

Other holders

(m)

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Insider holders

(m)

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Top institutional holders

(m)

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Top mutual fund holders

(m)

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AGIOS PHARMACEUTICALS, INC. Overview

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(m)

(m)

SEC CIK
1439222
Industry (SIC)
2834 Pharmaceutical Preparations
Country of operation
United States
Business address
88 SIDNEY STREET, CAMBRIDGE, Massachusetts, 02139, United States
Fiscal year end
1231
Phone
617-649-8600

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