XBI additions & removals
Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.
Additions
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2026-03-31 | Added / first present |
| Rocket Pharmaceuticals Inc | Rocket Pharmaceuticals Inc | 2026-03-31 | Added / first present |
| Vanda Pharmaceuticals Inc | Vanda Pharmaceuticals Inc | 2026-03-31 | Added / first present |
| Capricor Therapeutics Inc | Capricor Therapeutics Inc | 2026-03-31 | Added / first present |
| Ocugen Inc | Ocugen Inc | 2026-03-31 | Added / first present |
| SELLAS Life Sciences Group Inc | SELLAS Life Sciences Group Inc | 2026-03-31 | Added / first present |
| Perspective Therapeutics Inc | Perspective Therapeutics Inc | 2026-03-31 | Added / first present |
| Zenas Biopharma Inc | Zenas Biopharma Inc | 2026-03-31 | Added / first present |
| Damora Therapeutics Inc | Damora Therapeutics Inc | 2026-03-31 | Added / first present |
| Vor BioPharma Inc | Vor BioPharma Inc | 2026-03-31 | Added / first present |
| Hyperliquid Strategies Inc | Hyperliquid Strategies Inc | 2026-03-31 | Added / first present |
| Ironwood Pharmaceuticals Inc | Ironwood Pharmaceuticals Inc | 2025-12-31 | Added / first present |
| CytomX Therapeutics Inc | CytomX Therapeutics Inc | 2025-12-31 | Added / first present |
| Gossamer Bio Inc | Gossamer Bio Inc | 2025-12-31 | Added / first present |
| Savara Inc | Savara Inc | 2025-12-31 | Added / first present |
| Kodiak Sciences Inc | Kodiak Sciences Inc | 2025-12-31 | Added / first present |
| Corvus Pharmaceuticals Inc | Corvus Pharmaceuticals Inc | 2025-12-31 | Added / first present |
| Annexon Inc | Annexon Inc | 2025-12-31 | Added / first present |
| Olema Pharmaceuticals Inc | Olema Pharmaceuticals Inc | 2025-12-31 | Added / first present |
| 4D Molecular Therapeutics Inc | 4D Molecular Therapeutics Inc | 2025-12-31 | Added / first present |
| Monte Rosa Therapeutics Inc | Monte Rosa Therapeutics Inc | 2025-12-31 | Added / first present |
| Absci Corp | Absci Corp | 2025-12-31 | Added / first present |
| Immuneering Corp | Immuneering Corp | 2025-12-31 | Added / first present |
| Invivyd Inc | Invivyd Inc | 2025-12-31 | Added / first present |
| Erasca Inc | Erasca Inc | 2025-12-31 | Added / first present |
| Tyra Biosciences Inc | Tyra Biosciences Inc | 2025-12-31 | Added / first present |
| Prime Medicine Inc | Prime Medicine Inc | 2025-12-31 | Added / first present |
| Lexeo Therapeutics Inc | Lexeo Therapeutics Inc | 2025-12-31 | Added / first present |
| Inhibrx Biosciences Inc | Inhibrx Biosciences Inc | 2025-12-31 | Added / first present |
| Bicara Therapeutics Inc | Bicara Therapeutics Inc | 2025-12-31 | Added / first present |
| Palvella Therapeutics Inc | Palvella Therapeutics Inc | 2025-12-31 | Added / first present |
| Sionna Therapeutics Inc | Sionna Therapeutics Inc | 2025-12-31 | Added / first present |
| RAPT Therapeutics Inc | RAPT Therapeutics Inc | 2025-12-31 | Added / first present |
| CONTRA AKERO THERAPEUT | CONTRA AKERO THERAPEUT | 2025-12-31 | Added / first present |
| CONTRA METSERA INC | CONTRA METSERA INC | 2025-12-31 | Added / first present |
| Celcuity Inc | Celcuity Inc | 2025-09-30 | Added / first present |
| aTyr Pharma Inc | aTyr Pharma Inc | 2025-09-30 | Added / first present |
| Precigen Inc | Precigen Inc | 2025-09-30 | Added / first present |
| Sana Biotechnology Inc | Sana Biotechnology Inc | 2025-09-30 | Added / first present |
| Rezolute Inc | Rezolute Inc | 2025-09-30 | Added / first present |
| Tango Therapeutics Inc | Tango Therapeutics Inc | 2025-09-30 | Added / first present |
| Compass Therapeutics Inc | Compass Therapeutics Inc | 2025-09-30 | Added / first present |
| Cidara Therapeutics Inc | Cidara Therapeutics Inc | 2025-09-30 | Added / first present |
| Oruka Therapeutics Inc | Oruka Therapeutics Inc | 2025-09-30 | Added / first present |
| Upstream Bio Inc | Upstream Bio Inc | 2025-09-30 | Added / first present |
| CONTRA BLUEPRINT MEDIC | CONTRA BLUEPRINT MEDIC | 2025-09-30 | Added / first present |
| CONTRA VERVE THERAPEUT | CONTRA VERVE THERAPEUT | 2025-09-30 | Added / first present |
| REGENXBIO Inc | REGENXBIO Inc | 2025-06-30 | Added / first present |
| Taysha Gene Therapies Inc | Taysha Gene Therapies Inc | 2025-06-30 | Added / first present |
| Mineralys Therapeutics Inc | Mineralys Therapeutics Inc | 2025-06-30 | Added / first present |
| Verastem Inc | Verastem Inc | 2025-06-30 | Added / first present |
| Metsera Inc | Metsera Inc | 2025-06-30 | Added / first present |
| Organogenesis Holdings Inc | Organogenesis Holdings Inc | 2025-03-31 | Added / first present |
| Rigel Pharmaceuticals Inc | Rigel Pharmaceuticals Inc | 2025-03-31 | Added / first present |
| Sangamo Therapeutics Inc | Sangamo Therapeutics Inc | 2024-12-31 | Added / first present |
| Akebia Therapeutics Inc | Akebia Therapeutics Inc | 2024-12-31 | Added / first present |
| Capricor Therapeutics Inc | Capricor Therapeutics Inc | 2024-12-31 | Added / first present |
| Taysha Gene Therapies Inc | Taysha Gene Therapies Inc | 2024-12-31 | Added / first present |
| Monte Rosa Therapeutics Inc | Monte Rosa Therapeutics Inc | 2024-12-31 | Added / first present |
| Tourmaline Bio Inc | Tourmaline Bio Inc | 2024-12-31 | Added / first present |
| LENZ Therapeutics Inc | LENZ Therapeutics Inc | 2024-12-31 | Added / first present |
| GRAIL Inc | GRAIL Inc | 2024-12-31 | Added / first present |
| Emergent BioSolutions Inc | Emergent BioSolutions Inc | 2024-09-30 | Added / first present |
| Y-mAbs Therapeutics Inc | Y-mAbs Therapeutics Inc | 2024-09-30 | Added / first present |
| KalVista Pharmaceuticals Inc | KalVista Pharmaceuticals Inc | 2024-09-30 | Added / first present |
| Replimune Group Inc | Replimune Group Inc | 2024-09-30 | Added / first present |
| Arbutus Biopharma Corp | Arbutus Biopharma Corp | 2024-09-30 | Added / first present |
| Celcuity Inc | Celcuity Inc | 2024-09-30 | Added / first present |
| Applied Therapeutics Inc | Applied Therapeutics Inc | 2024-09-30 | Added / first present |
| Annexon Inc | Annexon Inc | 2024-09-30 | Added / first present |
| Erasca Inc | Erasca Inc | 2024-09-30 | Added / first present |
| Dianthus Therapeutics Inc | Dianthus Therapeutics Inc | 2024-09-30 | Added / first present |
| ArriVent Biopharma Inc | ArriVent Biopharma Inc | 2024-09-30 | Added / first present |
| Perspective Therapeutics Inc | Perspective Therapeutics Inc | 2024-09-30 | Added / first present |
| Heron Therapeutics Inc | Heron Therapeutics Inc | 2024-06-30 | Added / first present |
| Savara Inc | Savara Inc | 2024-06-30 | Added / first present |
| Stoke Therapeutics Inc | Stoke Therapeutics Inc | 2024-06-30 | Added / first present |
| Ocugen Inc | Ocugen Inc | 2024-06-30 | Added / first present |
| iTeos Therapeutics Inc | iTeos Therapeutics Inc | 2024-06-30 | Added / first present |
| Immunome Inc | Immunome Inc | 2024-06-30 | Added / first present |
| Janux Therapeutics Inc | Janux Therapeutics Inc | 2024-06-30 | Added / first present |
| Humacyte Inc | Humacyte Inc | 2024-06-30 | Added / first present |
| Corbus Pharmaceuticals Holdings Inc | Corbus Pharmaceuticals Holdings Inc | 2024-06-30 | Added / first present |
| Spyre Therapeutics Inc | Spyre Therapeutics Inc | 2024-06-30 | Added / first present |
| CG oncology Inc | CG oncology Inc | 2024-06-30 | Added / first present |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2024-06-30 | Added / first present |
| CONTRA INHIBRX INC | CONTRA INHIBRX INC | 2024-06-30 | Added / first present |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2024-03-31 | Added / first present |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2024-03-31 | Added / first present |
| AnaptysBio Inc | AnaptysBio Inc | 2024-03-31 | Added / first present |
| Voyager Therapeutics Inc | Voyager Therapeutics Inc | 2024-03-31 | Added / first present |
| Mersana Therapeutics Inc | Mersana Therapeutics Inc | 2024-03-31 | Added / first present |
| Altimmune Inc | Altimmune Inc | 2024-03-31 | Added / first present |
| Arcutis Biotherapeutics Inc | Arcutis Biotherapeutics Inc | 2024-03-31 | Added / first present |
| ORIC Pharmaceuticals Inc | ORIC Pharmaceuticals Inc | 2024-03-31 | Added / first present |
| Avita Medical Inc | Avita Medical Inc | 2024-03-31 | Added / first present |
| Nurix Therapeutics Inc | Nurix Therapeutics Inc | 2024-03-31 | Added / first present |
| Olema Pharmaceuticals Inc | Olema Pharmaceuticals Inc | 2024-03-31 | Added / first present |
| C4 Therapeutics Inc | C4 Therapeutics Inc | 2024-03-31 | Added / first present |
| ARS Pharmaceuticals Inc | ARS Pharmaceuticals Inc | 2024-03-31 | Added / first present |
| Cullinan Oncology Inc | Cullinan Oncology Inc | 2024-03-31 | Added / first present |
| Summit Therapeutics Inc | Summit Therapeutics Inc | 2024-03-31 | Added / first present |
| Tango Therapeutics Inc | Tango Therapeutics Inc | 2024-03-31 | Added / first present |
| Astria Therapeutics Inc | Astria Therapeutics Inc | 2024-03-31 | Added / first present |
| Apogee Therapeutics Inc | Apogee Therapeutics Inc | 2024-03-31 | Added / first present |
| CONTRA MIRATI THERAPEU | CONTRA MIRATI THERAPEU | 2024-03-31 | Added / first present |
| Cargo Therapeutics Inc | Cargo Therapeutics Inc | 2024-03-31 | Added / first present |
| MacroGenics Inc | MacroGenics Inc | 2023-12-31 | Added / first present |
| Scholar Rock Holding Corp | Scholar Rock Holding Corp | 2023-12-31 | Added / first present |
| Alpine Immune Sciences Inc | Alpine Immune Sciences Inc | 2023-12-31 | Added / first present |
| ImmunityBio Inc | ImmunityBio Inc | 2023-12-31 | Added / first present |
| Soleno Therapeutics Inc | Soleno Therapeutics Inc | 2023-12-31 | Added / first present |
| Coherus Biosciences Inc | Coherus Biosciences Inc | 2023-09-30 | Added / first present |
| Cabaletta Bio Inc | Cabaletta Bio Inc | 2023-09-30 | Added / first present |
| Vera Therapeutics Inc | Vera Therapeutics Inc | 2023-09-30 | Added / first present |
| Caribou Biosciences Inc | Caribou Biosciences Inc | 2023-09-30 | Added / first present |
| Prime Medicine Inc | Prime Medicine Inc | 2023-09-30 | Added / first present |
| Disc Medicine Inc | Disc Medicine Inc | 2023-09-30 | Added / first present |
| ACELYRIN Inc | ACELYRIN Inc | 2023-09-30 | Added / first present |
| Aldeyra Therapeutics Inc | Aldeyra Therapeutics Inc | 2023-06-30 | Added / first present |
| Dyne Therapeutics Inc | Dyne Therapeutics Inc | 2023-06-30 | Added / first present |
| Biomea Fusion Inc | Biomea Fusion Inc | 2023-06-30 | Added / first present |
| MiNK Therapeutics Inc | MiNK Therapeutics Inc | 2023-06-30 | Added / first present |
| Viking Therapeutics Inc | Viking Therapeutics Inc | 2023-03-31 | Added / first present |
| Ardelyx Inc | Ardelyx Inc | 2023-03-31 | Added / first present |
| Bioxcel Therapeutics Inc | Bioxcel Therapeutics Inc | 2023-03-31 | Added / first present |
| 89bio Inc | 89bio Inc | 2023-03-31 | Added / first present |
| Scilex Holding Co | Scilex Holding Co | 2023-03-31 | Added / first present |
| Allakos Inc | Allakos Inc | 2022-12-31 | Added / first present |
| Sutro Biopharma Inc | Sutro Biopharma Inc | 2022-12-31 | Added / first present |
| Akero Therapeutics Inc | Akero Therapeutics Inc | 2022-12-31 | Added / first present |
| Immunovant Inc | Immunovant Inc | 2022-12-31 | Added / first present |
| 4D Molecular Therapeutics Inc | 4D Molecular Therapeutics Inc | 2022-12-31 | Added / first present |
| Nuvalent Inc | Nuvalent Inc | 2022-12-31 | Added / first present |
| OMNIAB INC | OMNIAB INC | 2022-12-31 | Added / first present |
| OMNIAB INC | OMNIAB INC | 2022-12-31 | Added / first present |
| Bluebird Bio Inc | Bluebird Bio Inc | 2022-09-30 | Added / first present |
| G1 Therapeutics Inc | G1 Therapeutics Inc | 2022-09-30 | Added / first present |
| Rhythm Pharmaceuticals Inc | Rhythm Pharmaceuticals Inc | 2022-09-30 | Added / first present |
| Alaunos Therapeutics Inc | Alaunos Therapeutics Inc | 2022-09-30 | Added / first present |
| Seres Therapeutics Inc | Seres Therapeutics Inc | 2022-09-30 | Added / first present |
| Mersana Therapeutics Inc | Mersana Therapeutics Inc | 2022-09-30 | Added / first present |
| Kezar Life Sciences Inc | Kezar Life Sciences Inc | 2022-09-30 | Added / first present |
| ADMA Biologics Inc | ADMA Biologics Inc | 2022-09-30 | Added / first present |
| Altimmune Inc | Altimmune Inc | 2022-09-30 | Added / first present |
| Mirum Pharmaceuticals Inc | Mirum Pharmaceuticals Inc | 2022-09-30 | Added / first present |
| RAPT Therapeutics Inc | RAPT Therapeutics Inc | 2022-09-30 | Added / first present |
| Inhibrx Inc | Inhibrx Inc | 2022-09-30 | Added / first present |
| Adicet Bio Inc | Adicet Bio Inc | 2022-09-30 | Added / first present |
| C4 Therapeutics Inc | C4 Therapeutics Inc | 2022-09-30 | Added / first present |
| Cogent Biosciences Inc | Cogent Biosciences Inc | 2022-09-30 | Added / first present |
| Design Therapeutics Inc | Design Therapeutics Inc | 2022-09-30 | Added / first present |
| Prometheus Biosciences Inc | Prometheus Biosciences Inc | 2022-09-30 | Added / first present |
| ImmunityBio Inc | ImmunityBio Inc | 2022-09-30 | Added / first present |
| Recursion Pharmaceuticals Inc | Recursion Pharmaceuticals Inc | 2022-09-30 | Added / first present |
| Viridian Therapeutics Inc | Viridian Therapeutics Inc | 2022-09-30 | Added / first present |
| Verve Therapeutics Inc | Verve Therapeutics Inc | 2022-09-30 | Added / first present |
| Day One Biopharmaceuticals Inc | Day One Biopharmaceuticals Inc | 2022-09-30 | Added / first present |
| Lyell Immunopharma Inc | Lyell Immunopharma Inc | 2022-09-30 | Added / first present |
| Erasca Inc | Erasca Inc | 2022-09-30 | Added / first present |
| Caribou Biosciences Inc | Caribou Biosciences Inc | 2022-09-30 | Added / first present |
| Arcellx Inc | Arcellx Inc | 2022-09-30 | Added / first present |
| CTI BioPharma Corp | CTI BioPharma Corp | 2022-06-30 | Added / first present |
| Nkarta Inc | Nkarta Inc | 2022-06-30 | Added / first present |
| Point Biopharma Global Inc | Point Biopharma Global Inc | 2022-06-30 | Added / first present |
| EQRx Inc | EQRx Inc | 2022-06-30 | Added / first present |
| Prometheus Biosciences Inc | Prometheus Biosciences Inc | 2022-03-31 | Added / first present |
| Gritstone bio Inc | Gritstone bio Inc | 2021-12-31 | Added / first present |
| Kezar Life Sciences Inc | Kezar Life Sciences Inc | 2021-12-31 | Added / first present |
| RAPT Therapeutics Inc | RAPT Therapeutics Inc | 2021-12-31 | Added / first present |
| Annexon Inc | Annexon Inc | 2021-12-31 | Added / first present |
| Kronos Bio Inc | Kronos Bio Inc | 2021-12-31 | Added / first present |
| Inhibrx Inc | Inhibrx Inc | 2021-12-31 | Added / first present |
| iTeos Therapeutics Inc | iTeos Therapeutics Inc | 2021-12-31 | Added / first present |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2021-12-31 | Added / first present |
| 4D Molecular Therapeutics Inc | 4D Molecular Therapeutics Inc | 2021-12-31 | Added / first present |
| Cullinan Oncology Inc | Cullinan Oncology Inc | 2021-12-31 | Added / first present |
| Verve Therapeutics Inc | Verve Therapeutics Inc | 2021-12-31 | Added / first present |
| Adagio Therapeutics Inc | Adagio Therapeutics Inc | 2021-12-31 | Added / first present |
| Aadi Bioscience Inc | Aadi Bioscience Inc | 2021-12-31 | Added / first present |
| 2seventy bio Inc | 2seventy bio Inc | 2021-12-31 | Added / first present |
| Crinetics Pharmaceuticals Inc | Crinetics Pharmaceuticals Inc | 2021-09-30 | Added / first present |
| Selecta Biosciences Inc | Selecta Biosciences Inc | 2021-09-30 | Added / first present |
| Lineage Cell Therapeutics Inc | Lineage Cell Therapeutics Inc | 2021-09-30 | Added / first present |
| Ideaya Biosciences Inc | Ideaya Biosciences Inc | 2021-09-30 | Added / first present |
| VistaGen Therapeutics Inc | VistaGen Therapeutics Inc | 2021-09-30 | Added / first present |
| Recursion Pharmaceuticals Inc | Recursion Pharmaceuticals Inc | 2021-09-30 | Added / first present |
| Rubius Therapeutics Inc | Rubius Therapeutics Inc | 2021-06-30 | Added / first present |
| Verastem Inc | Verastem Inc | 2021-06-30 | Added / first present |
| Morphic Holding Inc | Morphic Holding Inc | 2021-06-30 | Added / first present |
| Organogenesis Holdings Inc | Organogenesis Holdings Inc | 2021-06-30 | Added / first present |
| Avid Bioservices Inc | Avid Bioservices Inc | 2021-06-30 | Added / first present |
| Sesen Bio Inc | Sesen Bio Inc | 2021-06-30 | Added / first present |
| Harpoon Therapeutics Inc | Harpoon Therapeutics Inc | 2021-06-30 | Added / first present |
| Chinook Therapeutics Inc | Chinook Therapeutics Inc | 2021-06-30 | Added / first present |
| BioAtla Inc | BioAtla Inc | 2021-06-30 | Added / first present |
| MiMedx Group Inc | MiMedx Group Inc | 2021-06-30 | Added / first present |
| Sana Biotechnology Inc | Sana Biotechnology Inc | 2021-06-30 | Added / first present |
| Aldeyra Therapeutics Inc | Aldeyra Therapeutics Inc | 2021-03-31 | Added / first present |
| KalVista Pharmaceuticals Inc | KalVista Pharmaceuticals Inc | 2021-03-31 | Added / first present |
| Sutro Biopharma Inc | Sutro Biopharma Inc | 2021-03-31 | Added / first present |
| Spero Therapeutics Inc | Spero Therapeutics Inc | 2021-03-31 | Added / first present |
| Chimerix Inc | Chimerix Inc | 2021-03-31 | Added / first present |
| Anavex Life Sciences Corp | Anavex Life Sciences Corp | 2021-03-31 | Added / first present |
| Curis Inc | Curis Inc | 2021-03-31 | Added / first present |
| Ocugen Inc | Ocugen Inc | 2021-03-31 | Added / first present |
| Altimmune Inc | Altimmune Inc | 2021-03-31 | Added / first present |
| DermTech Inc | DermTech Inc | 2021-03-31 | Added / first present |
| Passage Bio Inc | Passage Bio Inc | 2021-03-31 | Added / first present |
| ORIC Pharmaceuticals Inc | ORIC Pharmaceuticals Inc | 2021-03-31 | Added / first present |
| Annexon Inc | Annexon Inc | 2021-03-31 | Added / first present |
| Humanigen Inc | Humanigen Inc | 2021-03-31 | Added / first present |
| PMV Pharmaceuticals Inc | PMV Pharmaceuticals Inc | 2021-03-31 | Added / first present |
| Kymera Therapeutics Inc | Kymera Therapeutics Inc | 2021-03-31 | Added / first present |
| Prelude Therapeutics Inc | Prelude Therapeutics Inc | 2021-03-31 | Added / first present |
| Shattuck Labs Inc | Shattuck Labs Inc | 2021-03-31 | Added / first present |
| iTeos Therapeutics Inc | iTeos Therapeutics Inc | 2021-03-31 | Added / first present |
| Cerevel Therapeutics Holdings Inc | Cerevel Therapeutics Holdings Inc | 2021-03-31 | Added / first present |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2021-03-31 | Added / first present |
| C4 Therapeutics Inc | C4 Therapeutics Inc | 2021-03-31 | Added / first present |
| ImmunityBio Inc | ImmunityBio Inc | 2021-03-31 | Added / first present |
| Atreca Inc | Atreca Inc | 2020-12-31 | Added / first present |
| MannKind Corp | MannKind Corp | 2020-12-31 | Added / first present |
| Five Prime Therapeutics Inc | Five Prime Therapeutics Inc | 2020-12-31 | Added / first present |
| Scholar Rock Holding Corp | Scholar Rock Holding Corp | 2020-12-31 | Added / first present |
| Replimune Group Inc | Replimune Group Inc | 2020-12-31 | Added / first present |
| Seres Therapeutics Inc | Seres Therapeutics Inc | 2020-12-31 | Added / first present |
| Celldex Therapeutics Inc | Celldex Therapeutics Inc | 2020-12-31 | Added / first present |
| Akero Therapeutics Inc | Akero Therapeutics Inc | 2020-12-31 | Added / first present |
| Stoke Therapeutics Inc | Stoke Therapeutics Inc | 2020-12-31 | Added / first present |
| TCR2 Therapeutics Inc | TCR2 Therapeutics Inc | 2020-12-31 | Added / first present |
| Albireo Pharma Inc | Albireo Pharma Inc | 2020-12-31 | Added / first present |
| IVERIC bio Inc | IVERIC bio Inc | 2020-12-31 | Added / first present |
| Neoleukin Therapeutics Inc | Neoleukin Therapeutics Inc | 2020-12-31 | Added / first present |
| Cortexyme Inc | Cortexyme Inc | 2020-12-31 | Added / first present |
| Vaxart Inc | Vaxart Inc | 2020-12-31 | Added / first present |
| Precision BioSciences Inc | Precision BioSciences Inc | 2020-12-31 | Added / first present |
| Frequency Therapeutics Inc | Frequency Therapeutics Inc | 2020-12-31 | Added / first present |
| Vir Biotechnology Inc | Vir Biotechnology Inc | 2020-12-31 | Added / first present |
| Arcutis Biotherapeutics Inc | Arcutis Biotherapeutics Inc | 2020-12-31 | Added / first present |
| Beam Therapeutics Inc | Beam Therapeutics Inc | 2020-12-31 | Added / first present |
| Black Diamond Therapeutics Inc | Black Diamond Therapeutics Inc | 2020-12-31 | Added / first present |
| Forma Therapeutics Holdings Inc | Forma Therapeutics Holdings Inc | 2020-12-31 | Added / first present |
| Avidity Biosciences Inc | Avidity Biosciences Inc | 2020-12-31 | Added / first present |
| Zentalis Pharmaceuticals Inc | Zentalis Pharmaceuticals Inc | 2020-12-31 | Added / first present |
| Keros Therapeutics Inc | Keros Therapeutics Inc | 2020-12-31 | Added / first present |
| Applied Molecular Transport Inc | Applied Molecular Transport Inc | 2020-12-31 | Added / first present |
| Generation Bio Co | Generation Bio Co | 2020-12-31 | Added / first present |
| Cardiff Oncology Inc | Cardiff Oncology Inc | 2020-12-31 | Added / first present |
| Vaxcyte Inc | Vaxcyte Inc | 2020-12-31 | Added / first present |
| Seagen Inc | Seagen Inc | 2020-12-31 | Added / first present |
| Relay Therapeutics Inc | Relay Therapeutics Inc | 2020-12-31 | Added / first present |
| Nkarta Inc | Nkarta Inc | 2020-12-31 | Added / first present |
| ALX Oncology Holdings Inc | ALX Oncology Holdings Inc | 2020-12-31 | Added / first present |
| Allovir Inc | Allovir Inc | 2020-12-31 | Added / first present |
| Avita Therapeutics Inc | Avita Therapeutics Inc | 2020-12-31 | Added / first present |
| Nurix Therapeutics Inc | Nurix Therapeutics Inc | 2020-12-31 | Added / first present |
| LENSAR Inc | LENSAR Inc | 2020-12-31 | Added / first present |
| Travere Therapeutics Inc | Travere Therapeutics Inc | 2020-12-31 | Added / first present |
| Syndax Pharmaceuticals Inc | Syndax Pharmaceuticals Inc | 2020-09-30 | Added / first present |
| Rigel Pharmaceuticals Inc | Rigel Pharmaceuticals Inc | 2020-09-30 | Added / first present |
| Geron Corp | Geron Corp | 2020-09-30 | Added / first present |
| Lantheus Holdings Inc | Lantheus Holdings Inc | 2020-09-30 | Added / first present |
| Syros Pharmaceuticals Inc | Syros Pharmaceuticals Inc | 2020-09-30 | Added / first present |
| Arcturus Therapeutics Holdings Inc | Arcturus Therapeutics Holdings Inc | 2020-09-30 | Added / first present |
| Protagonist Therapeutics Inc | Protagonist Therapeutics Inc | 2020-09-30 | Added / first present |
| VBI Vaccines Inc | VBI Vaccines Inc | 2020-09-30 | Added / first present |
| SpringWorks Therapeutics Inc | SpringWorks Therapeutics Inc | 2020-09-30 | Added / first present |
| Immunovant Inc | Immunovant Inc | 2020-09-30 | Added / first present |
| Precigen Inc | Precigen Inc | 2020-09-30 | Added / first present |
| REVOLUTION Medicines Inc | REVOLUTION Medicines Inc | 2020-09-30 | Added / first present |
| Corbus Pharmaceuticals Holdings Inc | Corbus Pharmaceuticals Holdings Inc | 2020-06-30 | Added / first present |
| CytomX Therapeutics Inc | CytomX Therapeutics Inc | 2020-06-30 | Added / first present |
| Assembly Biosciences Inc | Assembly Biosciences Inc | 2020-06-30 | Added / first present |
| Inovio Pharmaceuticals Inc | Inovio Pharmaceuticals Inc | 2020-06-30 | Added / first present |
| Sorrento Therapeutics Inc | Sorrento Therapeutics Inc | 2020-06-30 | Added / first present |
| Novavax Inc | Novavax Inc | 2020-06-30 | Added / first present |
| PDL BioPharma Inc | PDL BioPharma Inc | 2020-06-30 | Added / first present |
| Arcus Biosciences Inc | Arcus Biosciences Inc | 2020-06-30 | Added / first present |
| Ardelyx Inc | Ardelyx Inc | 2020-06-30 | Added / first present |
| Translate Bio Inc | Translate Bio Inc | 2020-06-30 | Added / first present |
| Cue Biopharma Inc | Cue Biopharma Inc | 2020-06-30 | Added / first present |
| Mersana Therapeutics Inc | Mersana Therapeutics Inc | 2020-06-30 | Added / first present |
| CEL-SCI Corp | CEL-SCI Corp | 2020-06-30 | Added / first present |
| Athersys Inc | Athersys Inc | 2020-06-30 | Added / first present |
| Constellation Pharmaceuticals Inc | Constellation Pharmaceuticals Inc | 2020-06-30 | Added / first present |
| Bioxcel Therapeutics Inc | Bioxcel Therapeutics Inc | 2020-06-30 | Added / first present |
| IGM Biosciences Inc | IGM Biosciences Inc | 2020-06-30 | Added / first present |
| Viela Bio Inc | Viela Bio Inc | 2020-06-30 | Added / first present |
| ACHILLION PHARMACE COMMON STOCK | ACHILLION PHARMACE COMMON STOCK | 2020-03-31 | Added / first present |
| Precigen Inc | Precigen Inc | 2020-03-31 | Added / first present |
| Moderna Inc | Moderna Inc | 2019-12-31 | Added / first present |
| Principia Biopharma Inc | Principia Biopharma Inc | 2019-12-31 | Added / first present |
| ChemoCentryx Inc | ChemoCentryx Inc | 2019-12-31 | Added / first present |
| Agenus Inc | Agenus Inc | 2019-12-31 | Added / first present |
| Clovis Oncology Inc | Clovis Oncology Inc | 2019-12-31 | Added / first present |
| Dynavax Technologies Corp | Dynavax Technologies Corp | 2019-12-31 | Added / first present |
| NextCure Inc | NextCure Inc | 2019-12-31 | Added / first present |
| Gossamer Bio Inc | Gossamer Bio Inc | 2019-12-31 | Added / first present |
| Y-mAbs Therapeutics Inc | Y-mAbs Therapeutics Inc | 2019-12-31 | Added / first present |
| Alector Inc | Alector Inc | 2019-12-31 | Added / first present |
| Karuna Therapeutics Inc | Karuna Therapeutics Inc | 2019-12-31 | Added / first present |
| Bridgebio Pharma Inc | Bridgebio Pharma Inc | 2019-12-31 | Added / first present |
| Kadmon Holdings Inc | Kadmon Holdings Inc | 2019-12-31 | Added / first present |
| Kodiak Sciences Inc | Kodiak Sciences Inc | 2019-12-31 | Added / first present |
Removals
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| Gossamer Bio Inc | Gossamer Bio Inc | 2026-03-31 | Removed / first absent |
| Immuneering Corp | Immuneering Corp | 2026-03-31 | Removed / first absent |
| RAPT Therapeutics Inc | RAPT Therapeutics Inc | 2026-03-31 | Removed / first absent |
| aTyr Pharma Inc | aTyr Pharma Inc | 2025-12-31 | Removed / first absent |
| Rezolute Inc | Rezolute Inc | 2026-03-31 | Removed / first absent |
| Cidara Therapeutics Inc | Cidara Therapeutics Inc | 2026-03-31 | Removed / first absent |
| Upstream Bio Inc | Upstream Bio Inc | 2026-03-31 | Removed / first absent |
| Metsera Inc | Metsera Inc | 2025-12-31 | Removed / first absent |
| Organogenesis Holdings Inc | Organogenesis Holdings Inc | 2025-06-30 | Removed / first absent |
| Sangamo Therapeutics Inc | Sangamo Therapeutics Inc | 2025-03-31 | Removed / first absent |
| Capricor Therapeutics Inc | Capricor Therapeutics Inc | 2025-09-30 | Removed / first absent |
| Taysha Gene Therapies Inc | Taysha Gene Therapies Inc | 2025-03-31 | Removed / first absent |
| Monte Rosa Therapeutics Inc | Monte Rosa Therapeutics Inc | 2025-03-31 | Removed / first absent |
| Tourmaline Bio Inc | Tourmaline Bio Inc | 2025-03-31 | Removed / first absent |
| LENZ Therapeutics Inc | LENZ Therapeutics Inc | 2025-03-31 | Removed / first absent |
| Y-mAbs Therapeutics Inc | Y-mAbs Therapeutics Inc | 2025-03-31 | Removed / first absent |
| Celcuity Inc | Celcuity Inc | 2025-03-31 | Removed / first absent |
| Applied Therapeutics Inc | Applied Therapeutics Inc | 2024-12-31 | Removed / first absent |
| Annexon Inc | Annexon Inc | 2025-03-31 | Removed / first absent |
| Erasca Inc | Erasca Inc | 2025-03-31 | Removed / first absent |
| Perspective Therapeutics Inc | Perspective Therapeutics Inc | 2024-12-31 | Removed / first absent |
| Heron Therapeutics Inc | Heron Therapeutics Inc | 2024-09-30 | Removed / first absent |
| Savara Inc | Savara Inc | 2025-03-31 | Removed / first absent |
| Ocugen Inc | Ocugen Inc | 2024-12-31 | Removed / first absent |
| iTeos Therapeutics Inc | iTeos Therapeutics Inc | 2024-12-31 | Removed / first absent |
| Humacyte Inc | Humacyte Inc | 2025-09-30 | Removed / first absent |
| Corbus Pharmaceuticals Holdings Inc | Corbus Pharmaceuticals Holdings Inc | 2024-12-31 | Removed / first absent |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2025-03-31 | Removed / first absent |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2024-12-31 | Removed / first absent |
| Voyager Therapeutics Inc | Voyager Therapeutics Inc | 2024-09-30 | Removed / first absent |
| Mersana Therapeutics Inc | Mersana Therapeutics Inc | 2024-06-30 | Removed / first absent |
| Avita Medical Inc | Avita Medical Inc | 2024-06-30 | Removed / first absent |
| Olema Pharmaceuticals Inc | Olema Pharmaceuticals Inc | 2025-03-31 | Removed / first absent |
| C4 Therapeutics Inc | C4 Therapeutics Inc | 2024-12-31 | Removed / first absent |
| Tango Therapeutics Inc | Tango Therapeutics Inc | 2024-12-31 | Removed / first absent |
| Astria Therapeutics Inc | Astria Therapeutics Inc | 2025-03-31 | Removed / first absent |
| Cargo Therapeutics Inc | Cargo Therapeutics Inc | 2025-03-31 | Removed / first absent |
| MacroGenics Inc | MacroGenics Inc | 2024-06-30 | Removed / first absent |
| Alpine Immune Sciences Inc | Alpine Immune Sciences Inc | 2024-06-30 | Removed / first absent |
| Coherus Biosciences Inc | Coherus Biosciences Inc | 2023-12-31 | Removed / first absent |
| Cabaletta Bio Inc | Cabaletta Bio Inc | 2024-09-30 | Removed / first absent |
| Caribou Biosciences Inc | Caribou Biosciences Inc | 2024-06-30 | Removed / first absent |
| Prime Medicine Inc | Prime Medicine Inc | 2023-12-31 | Removed / first absent |
| ACELYRIN Inc | ACELYRIN Inc | 2023-12-31 | Removed / first absent |
| Aldeyra Therapeutics Inc | Aldeyra Therapeutics Inc | 2023-12-31 | Removed / first absent |
| Biomea Fusion Inc | Biomea Fusion Inc | 2024-06-30 | Removed / first absent |
| MiNK Therapeutics Inc | MiNK Therapeutics Inc | 2023-09-30 | Removed / first absent |
| Bioxcel Therapeutics Inc | Bioxcel Therapeutics Inc | 2023-09-30 | Removed / first absent |
| 89bio Inc | 89bio Inc | 2025-12-31 | Removed / first absent |
| Scilex Holding Co | Scilex Holding Co | 2025-06-30 | Removed / first absent |
| Allakos Inc | Allakos Inc | 2023-09-30 | Removed / first absent |
| Sutro Biopharma Inc | Sutro Biopharma Inc | 2023-06-30 | Removed / first absent |
| Akero Therapeutics Inc | Akero Therapeutics Inc | 2025-12-31 | Removed / first absent |
| 4D Molecular Therapeutics Inc | 4D Molecular Therapeutics Inc | 2024-12-31 | Removed / first absent |
| Bluebird Bio Inc | Bluebird Bio Inc | 2024-03-31 | Removed / first absent |
| G1 Therapeutics Inc | G1 Therapeutics Inc | 2022-12-31 | Removed / first absent |
| Alaunos Therapeutics Inc | Alaunos Therapeutics Inc | 2022-12-31 | Removed / first absent |
| Seres Therapeutics Inc | Seres Therapeutics Inc | 2023-12-31 | Removed / first absent |
| Mersana Therapeutics Inc | Mersana Therapeutics Inc | 2023-09-30 | Removed / first absent |
| Kezar Life Sciences Inc | Kezar Life Sciences Inc | 2023-06-30 | Removed / first absent |
| Altimmune Inc | Altimmune Inc | 2023-06-30 | Removed / first absent |
| RAPT Therapeutics Inc | RAPT Therapeutics Inc | 2024-03-31 | Removed / first absent |
| Inhibrx Inc | Inhibrx Inc | 2024-06-30 | Removed / first absent |
| Adicet Bio Inc | Adicet Bio Inc | 2023-03-31 | Removed / first absent |
| C4 Therapeutics Inc | C4 Therapeutics Inc | 2023-03-31 | Removed / first absent |
| Design Therapeutics Inc | Design Therapeutics Inc | 2023-03-31 | Removed / first absent |
| Prometheus Biosciences Inc | Prometheus Biosciences Inc | 2023-06-30 | Removed / first absent |
| ImmunityBio Inc | ImmunityBio Inc | 2023-03-31 | Removed / first absent |
| Verve Therapeutics Inc | Verve Therapeutics Inc | 2025-09-30 | Removed / first absent |
| Lyell Immunopharma Inc | Lyell Immunopharma Inc | 2023-12-31 | Removed / first absent |
| Erasca Inc | Erasca Inc | 2023-03-31 | Removed / first absent |
| Caribou Biosciences Inc | Caribou Biosciences Inc | 2023-06-30 | Removed / first absent |
| CTI BioPharma Corp | CTI BioPharma Corp | 2023-06-30 | Removed / first absent |
| Nkarta Inc | Nkarta Inc | 2022-12-31 | Removed / first absent |
| Point Biopharma Global Inc | Point Biopharma Global Inc | 2023-12-31 | Removed / first absent |
| EQRx Inc | EQRx Inc | 2023-12-31 | Removed / first absent |
| Prometheus Biosciences Inc | Prometheus Biosciences Inc | 2022-06-30 | Removed / first absent |
| Gritstone bio Inc | Gritstone bio Inc | 2022-03-31 | Removed / first absent |
| Kezar Life Sciences Inc | Kezar Life Sciences Inc | 2022-06-30 | Removed / first absent |
| RAPT Therapeutics Inc | RAPT Therapeutics Inc | 2022-06-30 | Removed / first absent |
| Annexon Inc | Annexon Inc | 2022-03-31 | Removed / first absent |
| Kronos Bio Inc | Kronos Bio Inc | 2022-06-30 | Removed / first absent |
| Inhibrx Inc | Inhibrx Inc | 2022-06-30 | Removed / first absent |
| iTeos Therapeutics Inc | iTeos Therapeutics Inc | 2023-12-31 | Removed / first absent |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2022-09-30 | Removed / first absent |
| 4D Molecular Therapeutics Inc | 4D Molecular Therapeutics Inc | 2022-06-30 | Removed / first absent |
| Cullinan Oncology Inc | Cullinan Oncology Inc | 2022-06-30 | Removed / first absent |
| Verve Therapeutics Inc | Verve Therapeutics Inc | 2022-06-30 | Removed / first absent |
| Adagio Therapeutics Inc | Adagio Therapeutics Inc | 2022-03-31 | Removed / first absent |
| Aadi Bioscience Inc | Aadi Bioscience Inc | 2022-09-30 | Removed / first absent |
| 2seventy bio Inc | 2seventy bio Inc | 2023-09-30 | Removed / first absent |
| Crinetics Pharmaceuticals Inc | Crinetics Pharmaceuticals Inc | 2025-09-30 | Removed / first absent |
| Selecta Biosciences Inc | Selecta Biosciences Inc | 2021-12-31 | Removed / first absent |
| Lineage Cell Therapeutics Inc | Lineage Cell Therapeutics Inc | 2021-12-31 | Removed / first absent |
| VistaGen Therapeutics Inc | VistaGen Therapeutics Inc | 2022-03-31 | Removed / first absent |
| Recursion Pharmaceuticals Inc | Recursion Pharmaceuticals Inc | 2022-03-31 | Removed / first absent |
| Rubius Therapeutics Inc | Rubius Therapeutics Inc | 2022-03-31 | Removed / first absent |
| Verastem Inc | Verastem Inc | 2022-03-31 | Removed / first absent |
| Morphic Holding Inc | Morphic Holding Inc | 2024-09-30 | Removed / first absent |
| Organogenesis Holdings Inc | Organogenesis Holdings Inc | 2022-09-30 | Removed / first absent |
| Avid Bioservices Inc | Avid Bioservices Inc | 2025-03-31 | Removed / first absent |
| Sesen Bio Inc | Sesen Bio Inc | 2021-09-30 | Removed / first absent |
| Harpoon Therapeutics Inc | Harpoon Therapeutics Inc | 2021-09-30 | Removed / first absent |
| Chinook Therapeutics Inc | Chinook Therapeutics Inc | 2023-09-30 | Removed / first absent |
| BioAtla Inc | BioAtla Inc | 2022-03-31 | Removed / first absent |
| Sana Biotechnology Inc | Sana Biotechnology Inc | 2025-06-30 | Removed / first absent |
| Aldeyra Therapeutics Inc | Aldeyra Therapeutics Inc | 2022-03-31 | Removed / first absent |
| KalVista Pharmaceuticals Inc | KalVista Pharmaceuticals Inc | 2022-06-30 | Removed / first absent |
| Sutro Biopharma Inc | Sutro Biopharma Inc | 2022-06-30 | Removed / first absent |
| Spero Therapeutics Inc | Spero Therapeutics Inc | 2022-03-31 | Removed / first absent |
| Chimerix Inc | Chimerix Inc | 2022-06-30 | Removed / first absent |
| Curis Inc | Curis Inc | 2022-03-31 | Removed / first absent |
| Ocugen Inc | Ocugen Inc | 2023-03-31 | Removed / first absent |
| Altimmune Inc | Altimmune Inc | 2022-03-31 | Removed / first absent |
| DermTech Inc | DermTech Inc | 2022-06-30 | Removed / first absent |
| Passage Bio Inc | Passage Bio Inc | 2021-09-30 | Removed / first absent |
| ORIC Pharmaceuticals Inc | ORIC Pharmaceuticals Inc | 2022-03-31 | Removed / first absent |
| Annexon Inc | Annexon Inc | 2021-09-30 | Removed / first absent |
| Humanigen Inc | Humanigen Inc | 2021-12-31 | Removed / first absent |
| PMV Pharmaceuticals Inc | PMV Pharmaceuticals Inc | 2023-03-31 | Removed / first absent |
| Prelude Therapeutics Inc | Prelude Therapeutics Inc | 2021-12-31 | Removed / first absent |
| Shattuck Labs Inc | Shattuck Labs Inc | 2021-09-30 | Removed / first absent |
| iTeos Therapeutics Inc | iTeos Therapeutics Inc | 2021-06-30 | Removed / first absent |
| Cerevel Therapeutics Holdings Inc | Cerevel Therapeutics Holdings Inc | 2024-09-30 | Removed / first absent |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2021-06-30 | Removed / first absent |
| C4 Therapeutics Inc | C4 Therapeutics Inc | 2022-06-30 | Removed / first absent |
| ImmunityBio Inc | ImmunityBio Inc | 2022-06-30 | Removed / first absent |
| Atreca Inc | Atreca Inc | 2021-06-30 | Removed / first absent |
| Five Prime Therapeutics Inc | Five Prime Therapeutics Inc | 2021-06-30 | Removed / first absent |
| Scholar Rock Holding Corp | Scholar Rock Holding Corp | 2022-06-30 | Removed / first absent |
| Replimune Group Inc | Replimune Group Inc | 2024-06-30 | Removed / first absent |
| Seres Therapeutics Inc | Seres Therapeutics Inc | 2022-06-30 | Removed / first absent |
| Akero Therapeutics Inc | Akero Therapeutics Inc | 2022-06-30 | Removed / first absent |
| Stoke Therapeutics Inc | Stoke Therapeutics Inc | 2022-06-30 | Removed / first absent |
| TCR2 Therapeutics Inc | TCR2 Therapeutics Inc | 2021-12-31 | Removed / first absent |
| Albireo Pharma Inc | Albireo Pharma Inc | 2022-09-30 | Removed / first absent |
| IVERIC bio Inc | IVERIC bio Inc | 2023-09-30 | Removed / first absent |
| Neoleukin Therapeutics Inc | Neoleukin Therapeutics Inc | 2021-09-30 | Removed / first absent |
| Cortexyme Inc | Cortexyme Inc | 2021-12-31 | Removed / first absent |
| Vaxart Inc | Vaxart Inc | 2022-12-31 | Removed / first absent |
| Precision BioSciences Inc | Precision BioSciences Inc | 2022-03-31 | Removed / first absent |
| Frequency Therapeutics Inc | Frequency Therapeutics Inc | 2021-06-30 | Removed / first absent |
| Arcutis Biotherapeutics Inc | Arcutis Biotherapeutics Inc | 2023-12-31 | Removed / first absent |
| Black Diamond Therapeutics Inc | Black Diamond Therapeutics Inc | 2021-06-30 | Removed / first absent |
| Forma Therapeutics Holdings Inc | Forma Therapeutics Holdings Inc | 2022-06-30 | Removed / first absent |
| Avidity Biosciences Inc | Avidity Biosciences Inc | 2026-03-31 | Removed / first absent |
| Zentalis Pharmaceuticals Inc | Zentalis Pharmaceuticals Inc | 2024-09-30 | Removed / first absent |
| Keros Therapeutics Inc | Keros Therapeutics Inc | 2026-03-31 | Removed / first absent |
| Applied Molecular Transport Inc | Applied Molecular Transport Inc | 2021-12-31 | Removed / first absent |
| Generation Bio Co | Generation Bio Co | 2022-03-31 | Removed / first absent |
| Cardiff Oncology Inc | Cardiff Oncology Inc | 2021-03-31 | Removed / first absent |
| Seagen Inc | Seagen Inc | 2023-12-31 | Removed / first absent |
| Nkarta Inc | Nkarta Inc | 2021-12-31 | Removed / first absent |
| ALX Oncology Holdings Inc | ALX Oncology Holdings Inc | 2022-06-30 | Removed / first absent |
| Allovir Inc | Allovir Inc | 2022-03-31 | Removed / first absent |
| Avita Therapeutics Inc | Avita Therapeutics Inc | 2022-03-31 | Removed / first absent |
| Nurix Therapeutics Inc | Nurix Therapeutics Inc | 2023-12-31 | Removed / first absent |
| LENSAR Inc | LENSAR Inc | 2021-03-31 | Removed / first absent |
| Rigel Pharmaceuticals Inc | Rigel Pharmaceuticals Inc | 2022-09-30 | Removed / first absent |
| Lantheus Holdings Inc | Lantheus Holdings Inc | 2020-12-31 | Removed / first absent |
| Syros Pharmaceuticals Inc | Syros Pharmaceuticals Inc | 2020-12-31 | Removed / first absent |
| Arcturus Therapeutics Holdings Inc | Arcturus Therapeutics Holdings Inc | 2025-12-31 | Removed / first absent |
| VBI Vaccines Inc | VBI Vaccines Inc | 2022-06-30 | Removed / first absent |
| SpringWorks Therapeutics Inc | SpringWorks Therapeutics Inc | 2025-09-30 | Removed / first absent |
| Immunovant Inc | Immunovant Inc | 2022-03-31 | Removed / first absent |
| Precigen Inc | Precigen Inc | 2022-03-31 | Removed / first absent |
| Corbus Pharmaceuticals Holdings Inc | Corbus Pharmaceuticals Holdings Inc | 2020-12-31 | Removed / first absent |
| CytomX Therapeutics Inc | CytomX Therapeutics Inc | 2022-03-31 | Removed / first absent |
| Assembly Biosciences Inc | Assembly Biosciences Inc | 2020-12-31 | Removed / first absent |
| Inovio Pharmaceuticals Inc | Inovio Pharmaceuticals Inc | 2023-06-30 | Removed / first absent |
| Sorrento Therapeutics Inc | Sorrento Therapeutics Inc | 2023-03-31 | Removed / first absent |
| PDL BioPharma Inc | PDL BioPharma Inc | 2020-12-31 | Removed / first absent |
| Ardelyx Inc | Ardelyx Inc | 2021-09-30 | Removed / first absent |
| Translate Bio Inc | Translate Bio Inc | 2021-09-30 | Removed / first absent |
| Cue Biopharma Inc | Cue Biopharma Inc | 2022-03-31 | Removed / first absent |
| Mersana Therapeutics Inc | Mersana Therapeutics Inc | 2022-03-31 | Removed / first absent |
| CEL-SCI Corp | CEL-SCI Corp | 2022-03-31 | Removed / first absent |
| Athersys Inc | Athersys Inc | 2021-06-30 | Removed / first absent |
| Constellation Pharmaceuticals Inc | Constellation Pharmaceuticals Inc | 2021-09-30 | Removed / first absent |
| Bioxcel Therapeutics Inc | Bioxcel Therapeutics Inc | 2022-06-30 | Removed / first absent |
| IGM Biosciences Inc | IGM Biosciences Inc | 2022-03-31 | Removed / first absent |
| Viela Bio Inc | Viela Bio Inc | 2021-03-31 | Removed / first absent |
| ACHILLION PHARMACE COMMON STOCK | ACHILLION PHARMACE COMMON STOCK | 2024-06-30 | Removed / first absent |
| Precigen Inc | Precigen Inc | 2020-06-30 | Removed / first absent |
| Principia Biopharma Inc | Principia Biopharma Inc | 2020-09-30 | Removed / first absent |
| ChemoCentryx Inc | ChemoCentryx Inc | 2022-12-31 | Removed / first absent |
| Agenus Inc | Agenus Inc | 2023-12-31 | Removed / first absent |
| Clovis Oncology Inc | Clovis Oncology Inc | 2022-03-31 | Removed / first absent |
| Dynavax Technologies Corp | Dynavax Technologies Corp | 2026-03-31 | Removed / first absent |
| NextCure Inc | NextCure Inc | 2020-06-30 | Removed / first absent |
| Gossamer Bio Inc | Gossamer Bio Inc | 2023-03-31 | Removed / first absent |
| Y-mAbs Therapeutics Inc | Y-mAbs Therapeutics Inc | 2022-12-31 | Removed / first absent |
| Alector Inc | Alector Inc | 2024-12-31 | Removed / first absent |
| Karuna Therapeutics Inc | Karuna Therapeutics Inc | 2024-03-31 | Removed / first absent |
| Kadmon Holdings Inc | Kadmon Holdings Inc | 2021-12-31 | Removed / first absent |
| Kodiak Sciences Inc | Kodiak Sciences Inc | 2022-03-31 | Removed / first absent |
| Celgene Corp | Celgene Corp | 2019-12-31 | Removed / first absent |
| Alexion Pharmaceuticals Inc | Alexion Pharmaceuticals Inc | 2021-09-30 | Removed / first absent |
| Seattle Genetics Inc | Seattle Genetics Inc | 2020-12-31 | Removed / first absent |
| Exact Sciences Corp | Exact Sciences Corp | 2026-03-31 | Removed / first absent |
| Sage Therapeutics Inc | Sage Therapeutics Inc | 2024-12-31 | Removed / first absent |
| Bluebird Bio Inc | Bluebird Bio Inc | 2022-06-30 | Removed / first absent |
| Portola Pharmaceuticals Inc | Portola Pharmaceuticals Inc | 2020-09-30 | Removed / first absent |
| Puma Biotechnology Inc | Puma Biotechnology Inc | 2021-09-30 | Removed / first absent |
| Allakos Inc | Allakos Inc | 2022-03-31 | Removed / first absent |
| Acceleron Pharma Inc | Acceleron Pharma Inc | 2021-12-31 | Removed / first absent |
| Arena Pharmaceuticals Inc | Arena Pharmaceuticals Inc | 2022-03-31 | Removed / first absent |
| Ra Pharmaceuticals Inc | Ra Pharmaceuticals Inc | 2020-06-30 | Removed / first absent |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2023-12-31 | Removed / first absent |
| Mirati Therapeutics Inc | Mirati Therapeutics Inc | 2024-03-31 | Removed / first absent |
| Blueprint Medicines Corp | Blueprint Medicines Corp | 2025-09-30 | Removed / first absent |
| Medicines Co/The | Medicines Co/The | 2020-03-31 | Removed / first absent |
| FibroGen Inc | FibroGen Inc | 2023-09-30 | Removed / first absent |
| Global Blood Therapeutics Inc | Global Blood Therapeutics Inc | 2022-12-31 | Removed / first absent |
| Immunomedics Inc | Immunomedics Inc | 2020-12-31 | Removed / first absent |
| Intercept Pharmaceuticals Inc | Intercept Pharmaceuticals Inc | 2023-12-31 | Removed / first absent |
| Ironwood Pharmaceuticals Inc | Ironwood Pharmaceuticals Inc | 2025-03-31 | Removed / first absent |
| Alder Biopharmaceuticals Inc | Alder Biopharmaceuticals Inc | 2019-12-31 | Removed / first absent |
| Coherus Biosciences Inc | Coherus Biosciences Inc | 2023-06-30 | Removed / first absent |
| REGENXBIO Inc | REGENXBIO Inc | 2025-03-31 | Removed / first absent |
| Aimmune Therapeutics Inc | Aimmune Therapeutics Inc | 2020-12-31 | Removed / first absent |
| Deciphera Pharmaceuticals Inc | Deciphera Pharmaceuticals Inc | 2024-06-30 | Removed / first absent |
| Momenta Pharmaceuticals Inc | Momenta Pharmaceuticals Inc | 2020-12-31 | Removed / first absent |
| OPKO Health Inc | OPKO Health Inc | 2022-06-30 | Removed / first absent |
| Audentes Therapeutics Inc | Audentes Therapeutics Inc | 2020-03-31 | Removed / first absent |
| Radius Health Inc | Radius Health Inc | 2022-09-30 | Removed / first absent |
| Editas Medicine Inc | Editas Medicine Inc | 2024-09-30 | Removed / first absent |
| Invitae Corp | Invitae Corp | 2022-03-31 | Removed / first absent |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2023-09-30 | Removed / first absent |
| AnaptysBio Inc | AnaptysBio Inc | 2023-12-31 | Removed / first absent |
| Esperion Therapeutics Inc | Esperion Therapeutics Inc | 2021-09-30 | Removed / first absent |
| Sangamo Therapeutics Inc | Sangamo Therapeutics Inc | 2023-06-30 | Removed / first absent |
| Spectrum Pharmaceuticals Inc | Spectrum Pharmaceuticals Inc | 2021-12-31 | Removed / first absent |
| Dicerna Pharmaceuticals Inc | Dicerna Pharmaceuticals Inc | 2021-12-31 | Removed / first absent |
| G1 Therapeutics Inc | G1 Therapeutics Inc | 2022-06-30 | Removed / first absent |
| Athenex Inc | Athenex Inc | 2021-09-30 | Removed / first absent |
| Epizyme Inc | Epizyme Inc | 2021-12-31 | Removed / first absent |
| Intrexon Corp | Intrexon Corp | 2020-03-31 | Removed / first absent |
| ArQule Inc | ArQule Inc | 2020-03-31 | Removed / first absent |
| Rhythm Pharmaceuticals Inc | Rhythm Pharmaceuticals Inc | 2022-03-31 | Removed / first absent |
| Heron Therapeutics Inc | Heron Therapeutics Inc | 2022-12-31 | Removed / first absent |
| Atara Biotherapeutics Inc | Atara Biotherapeutics Inc | 2023-06-30 | Removed / first absent |
| MacroGenics Inc | MacroGenics Inc | 2022-06-30 | Removed / first absent |
| Karyopharm Therapeutics Inc | Karyopharm Therapeutics Inc | 2023-06-30 | Removed / first absent |
| ZIOPHARM Oncology Inc | ZIOPHARM Oncology Inc | 2022-03-31 | Removed / first absent |
| Voyager Therapeutics Inc | Voyager Therapeutics Inc | 2020-09-30 | Removed / first absent |
| Flexion Therapeutics Inc | Flexion Therapeutics Inc | 2021-09-30 | Removed / first absent |
| Rocket Pharmaceuticals Inc | Rocket Pharmaceuticals Inc | 2025-06-30 | Removed / first absent |
| Achillion Pharmaceuticals Inc | Achillion Pharmaceuticals Inc | 2020-03-31 | Removed / first absent |
| Retrophin Inc | Retrophin Inc | 2020-12-31 | Removed / first absent |
| Akebia Therapeutics Inc | Akebia Therapeutics Inc | 2022-06-30 | Removed / first absent |
| Progenics Pharmaceuticals Inc | Progenics Pharmaceuticals Inc | 2020-06-30 | Removed / first absent |
| AMAG Pharmaceuticals Inc | AMAG Pharmaceuticals Inc | 2020-06-30 | Removed / first absent |
| ImmunoGen Inc | ImmunoGen Inc | 2024-03-31 | Removed / first absent |
| Viking Therapeutics Inc | Viking Therapeutics Inc | 2022-03-31 | Removed / first absent |
| Avrobio Inc | Avrobio Inc | 2021-09-30 | Removed / first absent |
| CytomX Therapeutics Inc | CytomX Therapeutics Inc | 2019-12-31 | Removed / first absent |
| Stemline Therapeutics Inc | Stemline Therapeutics Inc | 2020-06-30 | Removed / first absent |
| State Street Global Advisors | State Street Global Advisors | 2024-09-30 | Removed / first absent |
| Eagle Pharmaceuticals Inc/DE | Eagle Pharmaceuticals Inc/DE | 2023-03-31 | Removed / first absent |
| Enanta Pharmaceuticals Inc | Enanta Pharmaceuticals Inc | 2023-09-30 | Removed / first absent |
| Anika Therapeutics Inc | Anika Therapeutics Inc | 2023-09-30 | Removed / first absent |
| Repligen Corp | Repligen Corp | 2019-12-31 | Removed / first absent |
| Ligand Pharmaceuticals Inc | Ligand Pharmaceuticals Inc | 2022-12-31 | Removed / first absent |
| Emergent BioSolutions Inc | Emergent BioSolutions Inc | 2023-09-30 | Removed / first absent |
| Genomic Health Inc | Genomic Health Inc | 2019-12-31 | Removed / first absent |
| Vanda Pharmaceuticals Inc | Vanda Pharmaceuticals Inc | 2023-09-30 | Removed / first absent |
| Spark Therapeutics Inc | Spark Therapeutics Inc | 2019-12-31 | Removed / first absent |
| Akcea Therapeutics Inc | Akcea Therapeutics Inc | 2020-06-30 | Removed / first absent |
| Homology Medicines Inc | Homology Medicines Inc | 2020-09-30 | Removed / first absent |
| Adverum Biotechnologies Inc | Adverum Biotechnologies Inc | 2021-09-30 | Removed / first absent |
| Turning Point Therapeutics Inc | Turning Point Therapeutics Inc | 2022-09-30 | Removed / first absent |