| GILD | Gilead Sciences, Inc. | 6.480963% | 5,943,700.8 | 39,904 NS |
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| N/A | N/A | 6.343886% | 5,817,987.37 | 4,291 NC |
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| VRTX | Vertex Pharmaceuticals, Inc. | 6.273884% | 5,753,788.23 | 11,581 NS |
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| AMGN | Amgen, Inc. | 6.152311% | 5,642,293.76 | 14,536 NS |
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| REGN | Regeneron Pharmaceuticals, Inc. | 4.064745% | 3,727,784.23 | 4,769 NS |
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| N/A | N/A | 3.607338% | 3,308,295.63 | 2,484 NC |
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| N/A | N/A | 2.890727% | 2,651,090.1 | 2,639 NC |
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| N/A | N/A | 2.85019% | 2,613,913.81 | 6,179 NC |
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| N/A | N/A | 2.632957% | 2,414,689.32 | 3,646 NC |
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| ALNY | Alnylam Pharmaceuticals, Inc. | 2.214744% | 2,031,144.92 | 6,101 NS |
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| INVESCO GOVT AND AGCY LEX | INVESCO GOVT AND AGCY LEX | 1.813178% | 1,662,868.5 | 1,662,868.5 NS |
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| Repurchase Agreement | Repurchase Agreement | 1.709572% | 1,567,850.91 | 1,567,850.91 PA |
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| INSM | Insmed, Inc. | 1.603532% | 1,470,601.84 | 9,848 NS |
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| BIIB | Biogen, Inc. | 1.416843% | 1,299,388.68 | 6,774 NS |
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| ARGX | Argenx SE | 1.123911% | 1,030,740.48 | 1,344 NS |
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| UTHR | United Therapeutics Corp. | 1.092303% | 1,001,753.2 | 1,988 NS |
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| MRNA | Moderna, Inc. | 1.053699% | 966,349.23 | 18,039 NS |
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| ILMN | Illumina, Inc. | 1.034362% | 948,615.3 | 7,055 NS |
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| ROIV | Roivant Sciences Ltd. | 1.013387% | 929,379.16 | 32,114 NS |
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| INCY | Incyte Corp. | 1.000993% | 918,012.55 | 9,065 NS |
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| RPRX | Royalty Pharma plc | 0.994085% | 911,677.09 | 19,729 NS |
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| Revolution Medicines, Inc. | Revolution Medicines, Inc. | 0.993055% | 910,732.54 | 8,927 NS |
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| VTRS | Viatris, Inc. | 0.865795% | 794,022.19 | 53,183 NS |
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| Repurchase Agreement | Repurchase Agreement | 0.847208% | 776,975.55 | 776,975.55 PA |
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| Repurchase Agreement | Repurchase Agreement | 0.847208% | 776,975.55 | 776,975.55 PA |
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| ASND | Ascendis Pharma A/S | 0.721809% | 661,972.5 | 2,835 NS |
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| NBIX | Neurocrine Biosciences, Inc. | 0.663917% | 608,879 | 4,604 NS |
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| IONS | Ionis Pharmaceuticals, Inc. | 0.661782% | 606,920.85 | 7,479 NS |
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| Sanofi SA | Sanofi SA | 0.648321% | 594,576.54 | 12,219 NS |
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| BBIO | Bridgebio Pharma, Inc. | 0.644937% | 591,472.56 | 8,897 NS |
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| MEDP | Medpace Holdings, Inc. | 0.640867% | 587,739.76 | 1,301 NS |
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| SMMT | Summit Therapeutics, Inc. | 0.62183% | 570,281.25 | 34,375 NS |
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| GH | Guardant Health, Inc. | 0.611665% | 560,958.6 | 5,974 NS |
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| BMRN | BioMarin Pharmaceutical, Inc. | 0.597106% | 547,606.83 | 8,871 NS |
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| EXEL | Exelixis, Inc. | 0.594816% | 545,506.86 | 12,381 NS |
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| JAZZ | Jazz Pharmaceuticals plc | 0.581393% | 533,196.12 | 2,806 NS |
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| BNTX | BioNTech SE | 0.561185% | 514,663.87 | 4,669 NS |
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| Repurchase Agreement | Repurchase Agreement | 0.508325% | 466,185.33 | 466,185.33 PA |
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| Repurchase Agreement | Repurchase Agreement | 0.508325% | 466,185.33 | 466,185.33 PA |
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| BeOne Medicines Ltd. | BeOne Medicines Ltd. | 0.502565% | 460,903.46 | 1,454 NS |
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| MDGL | Madrigal Pharmaceuticals, Inc. | 0.49366% | 452,736 | 1,048 NS |
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| IBRX | ImmunityBio, Inc. | 0.485011% | 444,804.18 | 45,481 NS |
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| TEM | Tempus AI, Inc. | 0.463462% | 425,041.5 | 7,982 NS |
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| ARWR | Arrowhead Pharmaceuticals, Inc. | 0.432631% | 396,766.17 | 6,271 NS |
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| PRAX | Praxis Precision Medicines, Inc. | 0.424104% | 388,946.25 | 1,155 NS |
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| Repurchase Agreement | Repurchase Agreement | 0.423604% | 388,487.77 | 388,487.77 PA |
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| AXSM | Axsome Therapeutics, Inc. | 0.415845% | 381,372.03 | 2,327 NS |
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| HALO | Halozyme Therapeutics, Inc. | 0.411675% | 377,547.9 | 5,430 NS |
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| PCVX | Vaxcyte, Inc. | 0.406887% | 373,156.56 | 6,044 NS |
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| KRYS | Krystal Biotech, Inc. | 0.402444% | 369,081.96 | 1,339 NS |
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| CYTK | Cytokinetics, Inc. | 0.383048% | 351,294.12 | 5,646 NS |
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| Nuvalent, Inc. | Nuvalent, Inc. | 0.370737% | 340,003.25 | 3,335 NS |
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| Abivax SA | Abivax SA | 0.360494% | 330,609.28 | 2,726 NS |
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| Repurchase Agreement | Repurchase Agreement | 0.338883% | 310,790.22 | 310,790.22 PA |
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| Repurchase Agreement | Repurchase Agreement | 0.338883% | 310,790.22 | 310,790.22 PA |
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| Arcellx, Inc. | Arcellx, Inc. | 0.331282% | 303,819.3 | 2,670 NS |
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| KYMR | Kymera Therapeutics, Inc. | 0.330895% | 303,464.7 | 3,322 NS |
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| RYTM | Rhythm Pharmaceuticals, Inc. | 0.311627% | 285,793.86 | 3,082 NS |
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| COGT | Cogent Biosciences, Inc. | 0.30026% | 275,368.8 | 7,088 NS |
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| PTGX | Protagonist Therapeutics, Inc. | 0.289864% | 265,834.96 | 2,887 NS |
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| CRSP | CRISPR Therapeutics AG | 0.288535% | 264,616 | 4,400 NS |
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| CAI | Caris Life Sciences, Inc. | 0.286123% | 262,404.06 | 13,029 NS |
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| PTCT | PTC Therapeutics, Inc. | 0.27563% | 252,780.33 | 3,707 NS |
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| ALKS | Alkermes plc | 0.250226% | 229,482.4 | 7,624 NS |
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| IMVT | Immunovant, Inc. | 0.244735% | 224,446.62 | 8,094 NS |
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| CGON | CG oncology, Inc. | 0.238829% | 219,030 | 3,725 NS |
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| MIRM | Mirum Pharmaceuticals, Inc. | 0.2388% | 219,004.17 | 2,373 NS |
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| SRRK | Scholar Rock Holding Corp. | 0.227359% | 208,511.7 | 4,710 NS |
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| Amicus Therapeutics, Inc. | Amicus Therapeutics, Inc. | 0.223235% | 204,729.39 | 14,247 NS |
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| AMRX | Amneal Pharmaceuticals, Inc. | 0.218586% | 200,465.96 | 14,516 NS |
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| GPCR | Structure Therapeutics, Inc. | 0.211924% | 194,356.28 | 3,086 NS |
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| ACAD | ACADIA Pharmaceuticals, Inc. | 0.209206% | 191,862.72 | 7,812 NS |
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| INDV | Indivior Pharmaceuticals, Inc. | 0.20561% | 188,565.36 | 5,763 NS |
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| Newamsterdam Pharma Co. NV | Newamsterdam Pharma Co. NV | 0.202451% | 185,668.56 | 5,236 NS |
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| Ligand Pharmaceuticals, Inc. | Ligand Pharmaceuticals, Inc. | 0.196558% | 180,263.79 | 909 NS |
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| CRNX | Crinetics Pharmaceuticals, Inc. | 0.19638% | 180,100.2 | 4,382 NS |
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| ERAS | Erasca, Inc. | 0.195136% | 178,959.66 | 13,101 NS |
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| APGE | Apogee Therapeutics, Inc. | 0.193261% | 177,240 | 2,532 NS |
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| Terns Pharmaceuticals, Inc. | Terns Pharmaceuticals, Inc. | 0.191058% | 175,219.2 | 4,160 NS |
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| ADMA | ADMA Biologics, Inc. | 0.186582% | 171,114.3 | 10,990 NS |
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| Repurchase Agreement | Repurchase Agreement | 0.169442% | 155,395.11 | 155,395.11 PA |
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| XENE | Xenon Pharmaceuticals, Inc. | 0.168187% | 154,244.64 | 3,568 NS |
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| SYRE | Spyre Therapeutics, Inc. | 0.168035% | 154,104.83 | 3,583 NS |
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| ARQT | Arcutis Biotherapeutics, Inc. | 0.166331% | 152,542.32 | 5,656 NS |
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| EWTX | Edgewise Therapeutics, Inc. | 0.162273% | 148,821.16 | 4,889 NS |
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| TARS | Tarsus Pharmaceuticals, Inc. | 0.161481% | 148,094.72 | 1,961 NS |
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| SUPN | Supernus Pharmaceuticals, Inc. | 0.158025% | 144,925.04 | 2,648 NS |
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| DNLI | Denali Therapeutics, Inc. | 0.156396% | 143,430.96 | 6,772 NS |
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| VCYT | Veracyte, Inc. | 0.145626% | 133,553.5 | 3,650 NS |
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| BEAM | Beam Therapeutics, Inc. | 0.145388% | 133,335.1 | 4,685 NS |
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| ALMS | Alumis, Inc. | 0.145326% | 133,278.41 | 4,489 NS |
|---|
| TWST | Twist Bioscience Corp. | 0.144428% | 132,455.16 | 2,823 NS |
|---|
| IDYA | Ideaya Biosciences, Inc. | 0.142128% | 130,345.6 | 4,048 NS |
|---|
| TXG | 10X Genomics, Inc. | 0.135193% | 123,985.95 | 5,379 NS |
|---|
| TVTX | Travere Therapeutics, Inc. | 0.134186% | 123,062.49 | 4,131 NS |
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| Apellis Pharmaceuticals, Inc. | Apellis Pharmaceuticals, Inc. | 0.133448% | 122,385.44 | 5,839 NS |
|---|
| VERA | Vera Therapeutics, Inc. | 0.131207% | 120,330.5 | 2,950 NS |
|---|
| Centessa Pharmaceuticals plc | Centessa Pharmaceuticals plc | 0.130478% | 119,661.3 | 4,455 NS |
|---|
| IRON | Disc Medicine, Inc. | 0.126687% | 116,185.28 | 1,744 NS |
|---|
| ADPT | Adaptive Biotechnologies Corp. | 0.123132% | 112,924.98 | 7,049 NS |
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