GDOC additions & removals
Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.
Additions
| Ticker | Issuer | Observed date | Change |
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| BBIO | Bridgebio Pharma Inc | 2026-02-28 | Added / first present |
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| GPCR | Structure Therapeutics Inc | 2026-02-28 | Added / first present |
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| IONS | Ionis Pharmaceuticals, Inc. | 2026-02-28 | Added / first present |
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| MRK | Merck & Co., Inc | 2026-02-28 | Added / first present |
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| PEN | Penumbra Inc. | 2026-02-28 | Added / first present |
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| QGEN | QIAGEN NV | 2026-02-28 | Added / first present |
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| RGEN | Repligen Corporation | 2026-02-28 | Added / first present |
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| RPRX | Royalty Pharma PLC | 2026-02-28 | Added / first present |
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| ACLX | Arcellx Inc | 2025-11-30 | Added / first present |
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| CGON | CG oncology Inc | 2025-11-30 | Added / first present |
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| CYTK | Cytokinetics Inc | 2025-11-30 | Added / first present |
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| GH | Guardant Health Inc | 2025-11-30 | Added / first present |
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| JNJ | Johnson & Johnson | 2025-11-30 | Added / first present |
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| RYTM | Rhythm Pharmaceuticals Inc | 2025-11-30 | Added / first present |
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| WGS | GeneDx Holdings Corp | 2025-11-30 | Added / first present |
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| COR | Cencora Inc | 2025-08-31 | Added / first present |
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| DXCM | Dexcom Inc | 2025-08-31 | Added / first present |
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| INSM | Insmed Inc | 2025-08-31 | Added / first present |
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| RVMD | Revolution Medicines Inc | 2025-08-31 | Added / first present |
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| TMO | Thermo Fisher Scientific Inc | 2025-08-31 | Added / first present |
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| A | Agilent Technologies Inc | 2025-05-31 | Added / first present |
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| EXAS | Exact Sciences Corp | 2025-02-28 | Added / first present |
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| APGE | Apogee Therapeutics Inc | 2025-02-28 | Added / first present |
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| BNTX | BioNTech SE | 2025-02-28 | Added / first present |
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| UNH | UnitedHealth Group Inc | 2024-11-30 | Added / first present |
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| BPMC | Blueprint Medicines Corp | 2024-08-31 | Added / first present |
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| ABT | Abbott Laboratories | 2024-08-31 | Added / first present |
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| ANAB | AnaptysBio Inc | 2024-08-31 | Added / first present |
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| CLDX | Celldex Therapeutics Inc | 2024-08-31 | Added / first present |
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| DYN | Dyne Therapeutics Inc | 2024-08-31 | Added / first present |
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| MDGL | Madrigal Pharmaceuticals Inc | 2024-08-31 | Added / first present |
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| MRK | Merck & Co Inc | 2024-08-31 | Added / first present |
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| TMDX | TransMedics Group Inc | 2024-08-31 | Added / first present |
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| ABBV | AbbVie Inc | 2024-05-31 | Added / first present |
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| NTRA | Natera Inc | 2024-05-31 | Added / first present |
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| ROIV | Roivant Sciences Ltd | 2024-05-31 | Added / first present |
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| ITCI | Intra-Cellular Therapies Inc | 2024-02-29 | Added / first present |
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| AMGN | Amgen Inc | 2024-02-29 | Added / first present |
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| AMLX | Amylyx Pharmaceuticals Inc | 2024-02-29 | Added / first present |
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| CGON | CG oncology Inc | 2024-02-29 | Added / first present |
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| DYN | Dyne Therapeutics Inc | 2024-02-29 | Added / first present |
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| PCVX | Vaxcyte Inc | 2024-02-29 | Added / first present |
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| XENE | Xenon Pharmaceuticals Inc | 2024-02-29 | Added / first present |
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| FTOXX | Goldman Sachs Financial Square Treasury Obligations Fund | 2023-11-30 | Added / first present |
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| NOVOB | Novo Nordisk A/S | 2023-11-30 | Added / first present |
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| KRTX | Karuna Therapeutics Inc | 2023-11-30 | Added / first present |
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| HUM | Humana Inc | 2023-11-30 | Added / first present |
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| A | Agilent Technologies Inc | 2023-08-31 | Added / first present |
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| MLTX | MoonLake Immunotherapeutics | 2023-08-31 | Added / first present |
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| EXAS | Exact Sciences Corp | 2023-05-31 | Added / first present |
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| WAT | Waters Corp | 2023-02-28 | Added / first present |
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| ZTS | Zoetis Inc | 2023-02-28 | Added / first present |
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| SAGE | Sage Therapeutics Inc | 2022-11-30 | Added / first present |
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| LONN | Lonza Group AG | 2022-11-30 | Added / first present |
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| BMRN | BioMarin Pharmaceutical Inc | 2022-11-30 | Added / first present |
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| CYTK | Cytokinetics Inc | 2022-11-30 | Added / first present |
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| QGEN | QIAGEN NV | 2022-11-30 | Added / first present |
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Removals
| Ticker | Issuer | Observed date | Change |
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| EXAS | Exact Sciences Corp | 2025-08-31 | Removed / first absent |
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| BNTX | BioNTech SE | 2025-11-30 | Removed / first absent |
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| BPMC | Blueprint Medicines Corp | 2025-08-31 | Removed / first absent |
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| ANAB | AnaptysBio Inc | 2025-02-28 | Removed / first absent |
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| CLDX | Celldex Therapeutics Inc | 2024-11-30 | Removed / first absent |
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| DYN | Dyne Therapeutics Inc | 2024-11-30 | Removed / first absent |
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| MRK | Merck & Co Inc | 2025-08-31 | Removed / first absent |
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| TMDX | TransMedics Group Inc | 2025-02-28 | Removed / first absent |
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| ABBV | AbbVie Inc | 2025-11-30 | Removed / first absent |
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| ITCI | Intra-Cellular Therapies Inc | 2024-08-31 | Removed / first absent |
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| AMGN | Amgen Inc | 2025-02-28 | Removed / first absent |
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| AMLX | Amylyx Pharmaceuticals Inc | 2024-05-31 | Removed / first absent |
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| CGON | CG oncology Inc | 2025-05-31 | Removed / first absent |
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| DYN | Dyne Therapeutics Inc | 2024-05-31 | Removed / first absent |
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| PCVX | Vaxcyte Inc | 2025-05-31 | Removed / first absent |
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| NOVOB | Novo Nordisk A/S | 2026-02-28 | Removed / first absent |
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| KRTX | Karuna Therapeutics Inc | 2024-02-29 | Removed / first absent |
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| HUM | Humana Inc | 2024-11-30 | Removed / first absent |
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| A | Agilent Technologies Inc | 2024-08-31 | Removed / first absent |
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| MLTX | MoonLake Immunotherapeutics | 2025-11-30 | Removed / first absent |
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| EXAS | Exact Sciences Corp | 2024-05-31 | Removed / first absent |
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| WAT | Waters Corp | 2023-08-31 | Removed / first absent |
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| ZTS | Zoetis Inc | 2024-05-31 | Removed / first absent |
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| SAGE | Sage Therapeutics Inc | 2023-08-31 | Removed / first absent |
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| BMRN | BioMarin Pharmaceutical Inc | 2025-11-30 | Removed / first absent |
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| CYTK | Cytokinetics Inc | 2024-02-29 | Removed / first absent |
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| QGEN | QIAGEN NV | 2023-02-28 | Removed / first absent |
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| CTLT | Catalent Inc | 2023-05-31 | Removed / first absent |
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| SGEN | Seagen Inc | 2024-02-29 | Removed / first absent |
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| PKI | PerkinElmer Inc | 2022-11-30 | Removed / first absent |
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| 4519 | Chugai Pharmaceutical Co Ltd | 2024-05-31 | Removed / first absent |
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| 4151 | Kyowa Kirin Co Ltd | 2025-11-30 | Removed / first absent |
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| AXNX | Axonics Inc | 2024-02-29 | Removed / first absent |
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| SWAV | Shockwave Medical Inc | 2024-08-31 | Removed / first absent |
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| NARI | Inari Medical Inc | 2023-08-31 | Removed / first absent |
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| TSVT | 2seventy bio Inc | 2023-11-30 | Removed / first absent |
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| LONNZ | Lonza Group AG | 2022-11-30 | Removed / first absent |
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| AGIO | Agios Pharmaceuticals Inc | 2023-05-31 | Removed / first absent |
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| ALGN | Align Technology Inc | 2025-11-30 | Removed / first absent |
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| ALLO | Allogene Therapeutics Inc | 2023-05-31 | Removed / first absent |
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| ALNY | Alnylam Pharmaceuticals Inc | 2026-02-28 | Removed / first absent |
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| ARE | Alexandria Real Estate Equitie | 2024-05-31 | Removed / first absent |
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| BEAM | Beam Therapeutics Inc | 2023-11-30 | Removed / first absent |
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| BIIB | Biogen Inc | 2024-08-31 | Removed / first absent |
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| BMY | Bristol-Myers Squibb Co | 2024-05-31 | Removed / first absent |
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| CERT | Certara Inc | 2022-11-30 | Removed / first absent |
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| COO | Cooper Cos Inc/The | 2025-11-30 | Removed / first absent |
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| CSL | CSL Ltd | 2025-08-31 | Removed / first absent |
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| DHR | Danaher Corp | 2026-02-28 | Removed / first absent |
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| DXCM | Dexcom Inc | 2024-08-31 | Removed / first absent |
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| EW | Edwards Lifesciences Corp | 2024-08-31 | Removed / first absent |
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| EXEL | Exelixis Inc | 2023-08-31 | Removed / first absent |
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| GH | Guardant Health Inc | 2023-02-28 | Removed / first absent |
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| GILD | Gilead Sciences Inc | 2024-02-29 | Removed / first absent |
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| GMAB | Genmab A/S | 2025-02-28 | Removed / first absent |
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| HALO | Halozyme Therapeutics Inc | 2024-02-29 | Removed / first absent |
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| IDXX | IDEXX Laboratories Inc | 2025-02-28 | Removed / first absent |
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| ILMN | Illumina Inc | 2024-08-31 | Removed / first absent |
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| IRTC | iRhythm Technologies Inc | 2026-02-28 | Removed / first absent |
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| MXCT | MaxCyte Inc | 2023-02-28 | Removed / first absent |
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| NBIX | Neurocrine Biosciences Inc | 2026-02-28 | Removed / first absent |
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| NOVT | Novanta Inc | 2024-05-31 | Removed / first absent |
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| ONT | Oxford Nanopore Technologies P | 2024-02-29 | Removed / first absent |
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| PACB | Pacific Biosciences of Califor | 2022-11-30 | Removed / first absent |
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| PHVS | Pharvaris NV | 2022-11-30 | Removed / first absent |
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| SRPT | Sarepta Therapeutics Inc | 2023-11-30 | Removed / first absent |
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| STVN | Stevanato Group SpA | 2024-05-31 | Removed / first absent |
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| TNDM | Tandem Diabetes Care Inc | 2022-11-30 | Removed / first absent |
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| VEEV | Veeva Systems Inc | 2026-02-28 | Removed / first absent |
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| WST | West Pharmaceutical Services I | 2026-02-28 | Removed / first absent |
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| ZBH | Zimmer Biomet Holdings Inc | 2024-11-30 | Removed / first absent |
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