HELX additions & removals
Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.
Additions
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| ANAB | AnaptysBio Inc. | 2026-03-31 | Added / first present |
| TARS | Tarsus Pharmaceuticals Inc | 2026-03-31 | Added / first present |
| 0126Z0 | Samsung Episholdings Co Ltd | 2025-12-31 | Added / first present |
| ARQT | Arcutis Biotherapeutics Inc | 2025-12-31 | Added / first present |
| AXSM | Axsome Therapeutics Inc | 2025-12-31 | Added / first present |
| JAZZ | Jazz Pharmaceuticals PLC | 2025-12-31 | Added / first present |
| PRAX | Praxis Precision Medicines Inc | 2025-12-31 | Added / first present |
| RYTM | Rhythm Pharmaceuticals Inc | 2025-12-31 | Added / first present |
| EXAS | Exact Sciences Corp | 2025-09-30 | Added / first present |
| 207940 | Samsung Biologics Co Ltd | 2025-09-30 | Added / first present |
| SRT3 | Sartorius AG | 2025-09-30 | Added / first present |
| LONN | Lonza Group AG | 2025-09-30 | Added / first present |
| CPRX | Catalyst Pharmaceuticals Inc | 2025-09-30 | Added / first present |
| DVAX | Dynavax Technologies Corp | 2025-09-30 | Added / first present |
| 2200963D | OmniAb, Inc. | 2025-09-30 | Added / first present |
| 2200964D | OmniAb, Inc. | 2025-09-30 | Added / first present |
| A | Agilent Technologies Inc | 2025-09-30 | Added / first present |
| ADPT | Adaptive Biotechnologies Corp | 2025-09-30 | Added / first present |
| ALNY | Alnylam Pharmaceuticals Inc | 2025-09-30 | Added / first present |
| ARGX | Argenx SE | 2025-09-30 | Added / first present |
| AZN | AstraZeneca PLC | 2025-09-30 | Added / first present |
| BAVA | Bavarian Nordic A/S | 2025-09-30 | Added / first present |
| BBIO | Bridgebio Pharma Inc | 2025-09-30 | Added / first present |
| BEAM | Beam Therapeutics Inc | 2025-09-30 | Added / first present |
| BIO | Bio-Rad Laboratories Inc | 2025-09-30 | Added / first present |
| BMRN | BioMarin Pharmaceutical Inc | 2025-09-30 | Added / first present |
| BMY | Bristol-Myers Squibb Co | 2025-09-30 | Added / first present |
| BNTX | BioNTech SE | 2025-09-30 | Added / first present |
| CAI | Caris Life Sciences Inc | 2025-09-30 | Added / first present |
| CDNA | CareDx Inc | 2025-09-30 | Added / first present |
| CDNS | Cadence Design Systems Inc | 2025-09-30 | Added / first present |
| CRL | Charles River Laboratories Int | 2025-09-30 | Added / first present |
| CRSP | CRISPR Therapeutics AG | 2025-09-30 | Added / first present |
| CTVA | Corteva Inc | 2025-09-30 | Added / first present |
| DHR | Danaher Corp | 2025-09-30 | Added / first present |
| DOCS | Doximity Inc | 2025-09-30 | Added / first present |
| EVT | Evotec SE | 2025-09-30 | Added / first present |
| GH | Guardant Health Inc | 2025-09-30 | Added / first present |
| GRAL | GRAIL Inc | 2025-09-30 | Added / first present |
| HNGE | Hinge Health Inc | 2025-09-30 | Added / first present |
| INSM | Insmed Inc | 2025-09-30 | Added / first present |
| IONS | Ionis Pharmaceuticals Inc | 2025-09-30 | Added / first present |
| IQV | IQVIA Holdings Inc | 2025-09-30 | Added / first present |
| KRYS | Krystal Biotech Inc | 2025-09-30 | Added / first present |
| LGND | Ligand Pharmaceuticals Inc | 2025-09-30 | Added / first present |
| LH | Labcorp Holdings Inc | 2025-09-30 | Added / first present |
| LLY | Eli Lilly & Co | 2025-09-30 | Added / first present |
| MEDP | Medpace Holdings Inc | 2025-09-30 | Added / first present |
| NBIX | Neurocrine Biosciences Inc | 2025-09-30 | Added / first present |
| NGNE | Neurogene Inc | 2025-09-30 | Added / first present |
| NTRA | Natera Inc | 2025-09-30 | Added / first present |
| ONC | BeOne Medicines Ltd | 2025-09-30 | Added / first present |
| PTCT | PTC Therapeutics Inc | 2025-09-30 | Added / first present |
| QGEN | QIAGEN NV | 2025-09-30 | Added / first present |
| QURE | uniQure NV | 2025-09-30 | Added / first present |
| RARE | Ultragenyx Pharmaceutical Inc | 2025-09-30 | Added / first present |
| REGN | Regeneron Pharmaceuticals Inc | 2025-09-30 | Added / first present |
| RGEN | Repligen Corp | 2025-09-30 | Added / first present |
| RVTY | Revvity Inc | 2025-09-30 | Added / first present |
| RXRX | Recursion Pharmaceuticals Inc | 2025-09-30 | Added / first present |
| SDGR | Schrodinger Inc/United States | 2025-09-30 | Added / first present |
| STOK | Stoke Therapeutics Inc | 2025-09-30 | Added / first present |
| TECH | Bio-Techne Corp | 2025-09-30 | Added / first present |
| TEM | Tempus AI Inc | 2025-09-30 | Added / first present |
| TMDX | TransMedics Group Inc | 2025-09-30 | Added / first present |
| TMO | Thermo Fisher Scientific Inc | 2025-09-30 | Added / first present |
| TVTX | Travere Therapeutics Inc | 2025-09-30 | Added / first present |
| TWST | Twist Bioscience Corp | 2025-09-30 | Added / first present |
| UTHR | United Therapeutics Corp | 2025-09-30 | Added / first present |
| VCYT | Veracyte Inc | 2025-09-30 | Added / first present |
| VRTX | Vertex Pharmaceuticals Inc | 2025-09-30 | Added / first present |
| WGS | GeneDx Holdings Corp | 2025-09-30 | Added / first present |
| WVE | WaVe Life Sciences Ltd | 2025-09-30 | Added / first present |
| TransMedics Group Inc | TransMedics Group Inc | 2025-06-30 | Added / first present |
| Guardant Health Inc | Guardant Health Inc | 2025-03-31 | Added / first present |
| PTC Therapeutics Inc | PTC Therapeutics Inc | 2025-03-31 | Added / first present |
| CareDx Inc | CareDx Inc | 2025-03-31 | Added / first present |
| Catalyst Pharmaceuticals Inc | Catalyst Pharmaceuticals Inc | 2025-03-31 | Added / first present |
| Adaptive Biotechnologies Corp | Adaptive Biotechnologies Corp | 2025-03-31 | Added / first present |
| Schrodinger Inc/United States | Schrodinger Inc/United States | 2025-03-31 | Added / first present |
| Travere Therapeutics Inc | Travere Therapeutics Inc | 2025-03-31 | Added / first present |
| GeneDx Holdings Corp | GeneDx Holdings Corp | 2025-03-31 | Added / first present |
| GRAIL Inc | GRAIL Inc | 2025-03-31 | Added / first present |
| Crinetics Pharmaceuticals Inc | Crinetics Pharmaceuticals Inc | 2024-12-31 | Added / first present |
| Doximity Inc | Doximity Inc | 2024-12-31 | Added / first present |
| BioMarin Pharmaceutical Inc | BioMarin Pharmaceutical Inc | 2024-09-30 | Added / first present |
| Tempus AI Inc | Tempus AI Inc | 2024-09-30 | Added / first present |
| Neurogene Inc | Neurogene Inc | 2024-06-30 | Added / first present |
| Labcorp Holdings Inc | Labcorp Holdings Inc | 2024-06-30 | Added / first present |
| Neurocrine Biosciences Inc | Neurocrine Biosciences Inc | 2024-03-31 | Added / first present |
| United Therapeutics Corp | United Therapeutics Corp | 2024-03-31 | Added / first present |
| Ultragenyx Pharmaceutical Inc | Ultragenyx Pharmaceutical Inc | 2024-03-31 | Added / first present |
| Insmed Inc | Insmed Inc | 2024-03-31 | Added / first present |
| Voyager Therapeutics Inc | Voyager Therapeutics Inc | 2024-03-31 | Added / first present |
| Bridgebio Pharma Inc | Bridgebio Pharma Inc | 2024-03-31 | Added / first present |
| Recursion Pharmaceuticals Inc | Recursion Pharmaceuticals Inc | 2024-03-31 | Added / first present |
| 10X Genomics Inc | 10X Genomics Inc | 2023-12-31 | Added / first present |
| 4D Molecular Therapeutics Inc | 4D Molecular Therapeutics Inc | 2023-12-31 | Added / first present |
| Pacific Biosciences of California Inc | Pacific Biosciences of California Inc | 2023-09-30 | Added / first present |
| Fortrea Holdings Inc | Fortrea Holdings Inc | 2023-09-30 | Added / first present |
| Natera Inc | Natera Inc | 2023-06-30 | Added / first present |
| Rocket Pharmaceuticals Inc | Rocket Pharmaceuticals Inc | 2023-06-30 | Added / first present |
| Exact Sciences Corp | Exact Sciences Corp | 2022-12-31 | Added / first present |
| OmniAb Inc | OmniAb Inc | 2022-12-31 | Added / first present |
| OMNIAB INC | OMNIAB INC | 2022-12-31 | Added / first present |
| OMNIAB INC | OMNIAB INC | 2022-12-31 | Added / first present |
| Cadence Design Systems Inc | Cadence Design Systems Inc | 2022-09-30 | Added / first present |
| Alnylam Pharmaceuticals Inc | Alnylam Pharmaceuticals Inc | 2022-09-30 | Added / first present |
| Ionis Pharmaceuticals Inc | Ionis Pharmaceuticals Inc | 2022-09-30 | Added / first present |
| Sarepta Therapeutics Inc | Sarepta Therapeutics Inc | 2022-09-30 | Added / first present |
| Guardant Health Inc | Guardant Health Inc | 2022-09-30 | Added / first present |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2022-09-30 | Added / first present |
| Simulations Plus Inc | Simulations Plus Inc | 2022-09-30 | Added / first present |
| Twist Bioscience Corp | Twist Bioscience Corp | 2022-09-30 | Added / first present |
| IVERIC bio Inc | IVERIC bio Inc | 2022-09-30 | Added / first present |
| Schrodinger Inc/United States | Schrodinger Inc/United States | 2022-09-30 | Added / first present |
| Privia Health Group Inc | Privia Health Group Inc | 2022-09-30 | Added / first present |
| Verve Therapeutics Inc | Verve Therapeutics Inc | 2022-09-30 | Added / first present |
| PTC Therapeutics Inc | PTC Therapeutics Inc | 2022-06-30 | Added / first present |
| UnitedHealth Group Inc | UnitedHealth Group Inc | 2022-03-31 | Added / first present |
| Vertex Pharmaceuticals Inc | Vertex Pharmaceuticals Inc | 2022-03-31 | Added / first present |
| Bristol-Myers Squibb Co | Bristol-Myers Squibb Co | 2022-03-31 | Added / first present |
| Laboratory Corp of America Holdings | Laboratory Corp of America Holdings | 2022-03-31 | Added / first present |
| Corteva Inc | Corteva Inc | 2022-03-31 | Added / first present |
| Eli Lilly & Co | Eli Lilly & Co | 2022-03-31 | Added / first present |
| FMC Corp | FMC Corp | 2022-03-31 | Added / first present |
| Doximity Inc | Doximity Inc | 2022-03-31 | Added / first present |
| Danaher Corp | Danaher Corp | 2021-12-31 | Added / first present |
| Regeneron Pharmaceuticals Inc | Regeneron Pharmaceuticals Inc | 2021-12-31 | Added / first present |
| GlaxoSmithKline PLC | GlaxoSmithKline PLC | 2021-12-31 | Added / first present |
| Alexandria Real Estate Equities Inc | Alexandria Real Estate Equities Inc | 2021-12-31 | Added / first present |
| AstraZeneca PLC | AstraZeneca PLC | 2021-12-31 | Added / first present |
| Vericel Corp | Vericel Corp | 2021-12-31 | Added / first present |
| Dynavax Technologies Corp | Dynavax Technologies Corp | 2021-12-31 | Added / first present |
| Krystal Biotech Inc | Krystal Biotech Inc | 2021-12-31 | Added / first present |
| Avid Bioservices Inc | Avid Bioservices Inc | 2021-12-31 | Added / first present |
| Fulgent Genetics Inc | Fulgent Genetics Inc | 2021-12-31 | Added / first present |
| Olink Holding AB | Olink Holding AB | 2021-12-31 | Added / first present |
| Codex DNA Inc | Codex DNA Inc | 2021-12-31 | Added / first present |
| Avantor Inc | Avantor Inc | 2021-09-30 | Added / first present |
| Accolade Inc | Accolade Inc | 2021-09-30 | Added / first present |
| Corteva Inc | Corteva Inc | 2021-06-30 | Added / first present |
| IQVIA Holdings Inc | IQVIA Holdings Inc | 2021-06-30 | Added / first present |
| Brooks Automation Inc | Brooks Automation Inc | 2021-06-30 | Added / first present |
| Taysha Gene Therapies Inc | Taysha Gene Therapies Inc | 2021-06-30 | Added / first present |
| Sana Biotechnology Inc | Sana Biotechnology Inc | 2021-06-30 | Added / first present |
| Moderna Inc | Moderna Inc | 2021-03-31 | Added / first present |
| Ligand Pharmaceuticals Inc | Ligand Pharmaceuticals Inc | 2021-03-31 | Added / first present |
| PPD Inc | PPD Inc | 2021-03-31 | Added / first present |
| Certara Inc | Certara Inc | 2021-03-31 | Added / first present |
| Maravai LifeSciences Holdings Inc | Maravai LifeSciences Holdings Inc | 2021-03-31 | Added / first present |
| Seer Inc | Seer Inc | 2021-03-31 | Added / first present |
| PTC Therapeutics Inc | PTC Therapeutics Inc | 2020-12-31 | Added / first present |
| Bio-Rad Laboratories Inc | Bio-Rad Laboratories Inc | 2020-12-31 | Added / first present |
| Twist Bioscience Corp | Twist Bioscience Corp | 2020-12-31 | Added / first present |
| Beam Therapeutics Inc | Beam Therapeutics Inc | 2020-12-31 | Added / first present |
| Invitae Corp | Invitae Corp | 2020-09-30 | Added / first present |
| Medpace Holdings Inc | Medpace Holdings Inc | 2020-09-30 | Added / first present |
| GoodRx Holdings Inc | GoodRx Holdings Inc | 2020-09-30 | Added / first present |
| Berkeley Lights Inc | Berkeley Lights Inc | 2020-09-30 | Added / first present |
| American Well Corp | American Well Corp | 2020-09-30 | Added / first present |
| Quidel Corp | Quidel Corp | 2020-06-30 | Added / first present |
| PerkinElmer Inc | PerkinElmer Inc | 2020-06-30 | Added / first present |
| Bio-Techne Corp | Bio-Techne Corp | 2020-06-30 | Added / first present |
| Luminex Corp | Luminex Corp | 2020-06-30 | Added / first present |
| NeoGenomics Inc | NeoGenomics Inc | 2020-06-30 | Added / first present |
Removals
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| EXAS | Exact Sciences Corp | 2026-03-31 | Removed / first absent |
| LONN | Lonza Group AG | 2025-12-31 | Removed / first absent |
| DVAX | Dynavax Technologies Corp | 2026-03-31 | Removed / first absent |
| BAVA | Bavarian Nordic A/S | 2025-12-31 | Removed / first absent |
| BMRN | BioMarin Pharmaceutical Inc | 2025-12-31 | Removed / first absent |
| DOCS | Doximity Inc | 2026-03-31 | Removed / first absent |
| EVT | Evotec SE | 2025-12-31 | Removed / first absent |
| LH | Labcorp Holdings Inc | 2025-12-31 | Removed / first absent |
| QURE | uniQure NV | 2025-12-31 | Removed / first absent |
| RVTY | Revvity Inc | 2025-12-31 | Removed / first absent |
| SDGR | Schrodinger Inc/United States | 2026-03-31 | Removed / first absent |
| TECH | Bio-Techne Corp | 2025-12-31 | Removed / first absent |
| TransMedics Group Inc | TransMedics Group Inc | 2025-09-30 | Removed / first absent |
| Guardant Health Inc | Guardant Health Inc | 2025-09-30 | Removed / first absent |
| PTC Therapeutics Inc | PTC Therapeutics Inc | 2025-09-30 | Removed / first absent |
| CareDx Inc | CareDx Inc | 2025-09-30 | Removed / first absent |
| Catalyst Pharmaceuticals Inc | Catalyst Pharmaceuticals Inc | 2025-09-30 | Removed / first absent |
| Adaptive Biotechnologies Corp | Adaptive Biotechnologies Corp | 2025-09-30 | Removed / first absent |
| Schrodinger Inc/United States | Schrodinger Inc/United States | 2025-09-30 | Removed / first absent |
| Travere Therapeutics Inc | Travere Therapeutics Inc | 2025-09-30 | Removed / first absent |
| GeneDx Holdings Corp | GeneDx Holdings Corp | 2025-09-30 | Removed / first absent |
| GRAIL Inc | GRAIL Inc | 2025-09-30 | Removed / first absent |
| Crinetics Pharmaceuticals Inc | Crinetics Pharmaceuticals Inc | 2025-03-31 | Removed / first absent |
| Doximity Inc | Doximity Inc | 2025-09-30 | Removed / first absent |
| BioMarin Pharmaceutical Inc | BioMarin Pharmaceutical Inc | 2025-09-30 | Removed / first absent |
| Tempus AI Inc | Tempus AI Inc | 2025-09-30 | Removed / first absent |
| Neurogene Inc | Neurogene Inc | 2025-09-30 | Removed / first absent |
| Labcorp Holdings Inc | Labcorp Holdings Inc | 2025-09-30 | Removed / first absent |
| Neurocrine Biosciences Inc | Neurocrine Biosciences Inc | 2025-09-30 | Removed / first absent |
| United Therapeutics Corp | United Therapeutics Corp | 2025-09-30 | Removed / first absent |
| Ultragenyx Pharmaceutical Inc | Ultragenyx Pharmaceutical Inc | 2025-09-30 | Removed / first absent |
| Insmed Inc | Insmed Inc | 2025-09-30 | Removed / first absent |
| Voyager Therapeutics Inc | Voyager Therapeutics Inc | 2025-06-30 | Removed / first absent |
| Bridgebio Pharma Inc | Bridgebio Pharma Inc | 2025-09-30 | Removed / first absent |
| Recursion Pharmaceuticals Inc | Recursion Pharmaceuticals Inc | 2025-09-30 | Removed / first absent |
| 10X Genomics Inc | 10X Genomics Inc | 2024-06-30 | Removed / first absent |
| 4D Molecular Therapeutics Inc | 4D Molecular Therapeutics Inc | 2025-06-30 | Removed / first absent |
| Pacific Biosciences of California Inc | Pacific Biosciences of California Inc | 2024-06-30 | Removed / first absent |
| Fortrea Holdings Inc | Fortrea Holdings Inc | 2024-06-30 | Removed / first absent |
| Natera Inc | Natera Inc | 2025-09-30 | Removed / first absent |
| Rocket Pharmaceuticals Inc | Rocket Pharmaceuticals Inc | 2025-06-30 | Removed / first absent |
| Exact Sciences Corp | Exact Sciences Corp | 2025-09-30 | Removed / first absent |
| OmniAb Inc | OmniAb Inc | 2023-03-31 | Removed / first absent |
| OMNIAB INC | OMNIAB INC | 2025-09-30 | Removed / first absent |
| OMNIAB INC | OMNIAB INC | 2025-09-30 | Removed / first absent |
| Cadence Design Systems Inc | Cadence Design Systems Inc | 2025-09-30 | Removed / first absent |
| Alnylam Pharmaceuticals Inc | Alnylam Pharmaceuticals Inc | 2025-09-30 | Removed / first absent |
| Ionis Pharmaceuticals Inc | Ionis Pharmaceuticals Inc | 2025-09-30 | Removed / first absent |
| Sarepta Therapeutics Inc | Sarepta Therapeutics Inc | 2025-06-30 | Removed / first absent |
| Guardant Health Inc | Guardant Health Inc | 2024-06-30 | Removed / first absent |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2023-03-31 | Removed / first absent |
| Simulations Plus Inc | Simulations Plus Inc | 2025-06-30 | Removed / first absent |
| Twist Bioscience Corp | Twist Bioscience Corp | 2025-09-30 | Removed / first absent |
| IVERIC bio Inc | IVERIC bio Inc | 2023-06-30 | Removed / first absent |
| Schrodinger Inc/United States | Schrodinger Inc/United States | 2024-06-30 | Removed / first absent |
| Privia Health Group Inc | Privia Health Group Inc | 2024-03-31 | Removed / first absent |
| Verve Therapeutics Inc | Verve Therapeutics Inc | 2023-03-31 | Removed / first absent |
| PTC Therapeutics Inc | PTC Therapeutics Inc | 2023-12-31 | Removed / first absent |
| UnitedHealth Group Inc | UnitedHealth Group Inc | 2022-09-30 | Removed / first absent |
| Vertex Pharmaceuticals Inc | Vertex Pharmaceuticals Inc | 2025-09-30 | Removed / first absent |
| Bristol-Myers Squibb Co | Bristol-Myers Squibb Co | 2025-09-30 | Removed / first absent |
| Laboratory Corp of America Holdings | Laboratory Corp of America Holdings | 2024-06-30 | Removed / first absent |
| Corteva Inc | Corteva Inc | 2025-09-30 | Removed / first absent |
| Eli Lilly & Co | Eli Lilly & Co | 2025-09-30 | Removed / first absent |
| FMC Corp | FMC Corp | 2023-09-30 | Removed / first absent |
| Doximity Inc | Doximity Inc | 2024-06-30 | Removed / first absent |
| Danaher Corp | Danaher Corp | 2025-09-30 | Removed / first absent |
| Regeneron Pharmaceuticals Inc | Regeneron Pharmaceuticals Inc | 2025-09-30 | Removed / first absent |
| GlaxoSmithKline PLC | GlaxoSmithKline PLC | 2022-09-30 | Removed / first absent |
| Alexandria Real Estate Equities Inc | Alexandria Real Estate Equities Inc | 2025-06-30 | Removed / first absent |
| AstraZeneca PLC | AstraZeneca PLC | 2025-09-30 | Removed / first absent |
| Vericel Corp | Vericel Corp | 2022-03-31 | Removed / first absent |
| Dynavax Technologies Corp | Dynavax Technologies Corp | 2025-09-30 | Removed / first absent |
| Krystal Biotech Inc | Krystal Biotech Inc | 2025-09-30 | Removed / first absent |
| Avid Bioservices Inc | Avid Bioservices Inc | 2025-03-31 | Removed / first absent |
| Fulgent Genetics Inc | Fulgent Genetics Inc | 2023-03-31 | Removed / first absent |
| Olink Holding AB | Olink Holding AB | 2024-09-30 | Removed / first absent |
| Codex DNA Inc | Codex DNA Inc | 2022-06-30 | Removed / first absent |
| Avantor Inc | Avantor Inc | 2025-06-30 | Removed / first absent |
| Accolade Inc | Accolade Inc | 2021-12-31 | Removed / first absent |
| Corteva Inc | Corteva Inc | 2021-12-31 | Removed / first absent |
| IQVIA Holdings Inc | IQVIA Holdings Inc | 2025-09-30 | Removed / first absent |
| Brooks Automation Inc | Brooks Automation Inc | 2025-09-30 | Removed / first absent |
| Taysha Gene Therapies Inc | Taysha Gene Therapies Inc | 2023-03-31 | Removed / first absent |
| Sana Biotechnology Inc | Sana Biotechnology Inc | 2022-03-31 | Removed / first absent |
| Moderna Inc | Moderna Inc | 2025-03-31 | Removed / first absent |
| Ligand Pharmaceuticals Inc | Ligand Pharmaceuticals Inc | 2025-09-30 | Removed / first absent |
| PPD Inc | PPD Inc | 2021-12-31 | Removed / first absent |
| Certara Inc | Certara Inc | 2022-03-31 | Removed / first absent |
| Maravai LifeSciences Holdings Inc | Maravai LifeSciences Holdings Inc | 2022-09-30 | Removed / first absent |
| Seer Inc | Seer Inc | 2022-03-31 | Removed / first absent |
| PTC Therapeutics Inc | PTC Therapeutics Inc | 2021-09-30 | Removed / first absent |
| Bio-Rad Laboratories Inc | Bio-Rad Laboratories Inc | 2025-09-30 | Removed / first absent |
| Twist Bioscience Corp | Twist Bioscience Corp | 2022-03-31 | Removed / first absent |
| Beam Therapeutics Inc | Beam Therapeutics Inc | 2025-09-30 | Removed / first absent |
| Invitae Corp | Invitae Corp | 2021-12-31 | Removed / first absent |
| Medpace Holdings Inc | Medpace Holdings Inc | 2025-09-30 | Removed / first absent |
| GoodRx Holdings Inc | GoodRx Holdings Inc | 2020-12-31 | Removed / first absent |
| Berkeley Lights Inc | Berkeley Lights Inc | 2021-09-30 | Removed / first absent |
| American Well Corp | American Well Corp | 2021-09-30 | Removed / first absent |
| Quidel Corp | Quidel Corp | 2021-03-31 | Removed / first absent |
| PerkinElmer Inc | PerkinElmer Inc | 2025-09-30 | Removed / first absent |
| Bio-Techne Corp | Bio-Techne Corp | 2025-09-30 | Removed / first absent |
| Luminex Corp | Luminex Corp | 2020-09-30 | Removed / first absent |
| NeoGenomics Inc | NeoGenomics Inc | 2022-03-31 | Removed / first absent |
| Bayer AG | Bayer AG | 2025-09-30 | Removed / first absent |
| NVIDIA Corp | NVIDIA Corp | 2022-09-30 | Removed / first absent |
| Thermo Fisher Scientific Inc | Thermo Fisher Scientific Inc | 2025-09-30 | Removed / first absent |
| Vertex Pharmaceuticals Inc | Vertex Pharmaceuticals Inc | 2020-12-31 | Removed / first absent |
| Agilent Technologies Inc | Agilent Technologies Inc | 2025-09-30 | Removed / first absent |
| Illumina Inc | Illumina Inc | 2023-09-30 | Removed / first absent |
| Veeva Systems Inc | Veeva Systems Inc | 2022-09-30 | Removed / first absent |
| Exact Sciences Corp | Exact Sciences Corp | 2021-12-31 | Removed / first absent |
| Alnylam Pharmaceuticals Inc | Alnylam Pharmaceuticals Inc | 2021-03-31 | Removed / first absent |
| Ionis Pharmaceuticals Inc | Ionis Pharmaceuticals Inc | 2020-12-31 | Removed / first absent |
| Sarepta Therapeutics Inc | Sarepta Therapeutics Inc | 2021-03-31 | Removed / first absent |
| Bluebird Bio Inc | Bluebird Bio Inc | 2020-09-30 | Removed / first absent |
| Charles River Laboratories International Inc | Charles River Laboratories International Inc | 2025-09-30 | Removed / first absent |
| Ultragenyx Pharmaceutical Inc | Ultragenyx Pharmaceutical Inc | 2021-09-30 | Removed / first absent |
| IQVIA Holdings Inc | IQVIA Holdings Inc | 2020-12-31 | Removed / first absent |
| Teladoc Health Inc | Teladoc Health Inc | 2021-09-30 | Removed / first absent |
| Guardant Health Inc | Guardant Health Inc | 2022-03-31 | Removed / first absent |
| 10X Genomics Inc | 10X Genomics Inc | 2022-03-31 | Removed / first absent |
| Livongo Health Inc | Livongo Health Inc | 2020-12-31 | Removed / first absent |
| Arrowhead Pharmaceuticals Inc | Arrowhead Pharmaceuticals Inc | 2020-06-30 | Removed / first absent |
| Iovance Biotherapeutics Inc | Iovance Biotherapeutics Inc | 2021-06-30 | Removed / first absent |
| Natera Inc | Natera Inc | 2022-03-31 | Removed / first absent |
| Amicus Therapeutics Inc | Amicus Therapeutics Inc | 2021-03-31 | Removed / first absent |
| REGENXBIO Inc | REGENXBIO Inc | 2020-09-30 | Removed / first absent |
| Editas Medicine Inc | Editas Medicine Inc | 2023-03-31 | Removed / first absent |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2021-12-31 | Removed / first absent |
| Veracyte Inc | Veracyte Inc | 2025-09-30 | Removed / first absent |
| NanoString Technologies Inc | NanoString Technologies Inc | 2022-06-30 | Removed / first absent |
| Intellia Therapeutics Inc | Intellia Therapeutics Inc | 2025-06-30 | Removed / first absent |
| Rocket Pharmaceuticals Inc | Rocket Pharmaceuticals Inc | 2021-09-30 | Removed / first absent |
| PRA Health Sciences Inc | PRA Health Sciences Inc | 2021-09-30 | Removed / first absent |
| Bruker Corp | Bruker Corp | 2025-09-30 | Removed / first absent |
| Medpace Holdings Inc | Medpace Holdings Inc | 2020-06-30 | Removed / first absent |
| Catalent Inc | Catalent Inc | 2022-12-31 | Removed / first absent |
| Repligen Corp | Repligen Corp | 2025-09-30 | Removed / first absent |
| Krystal Biotech Inc | Krystal Biotech Inc | 2020-09-30 | Removed / first absent |
| Pacific Biosciences of California Inc | Pacific Biosciences of California Inc | 2022-03-31 | Removed / first absent |
| Homology Medicines Inc | Homology Medicines Inc | 2020-09-30 | Removed / first absent |
| Model N Inc | Model N Inc | 2020-12-31 | Removed / first absent |
| Cellectis SA | Cellectis SA | 2021-03-31 | Removed / first absent |
| CryoPort Inc | CryoPort Inc | 2022-06-30 | Removed / first absent |
| Prevail Therapeutics Inc | Prevail Therapeutics Inc | 2020-09-30 | Removed / first absent |
| Precision BioSciences Inc | Precision BioSciences Inc | 2020-06-30 | Removed / first absent |
| BioNTech SE | BioNTech SE | 2025-09-30 | Removed / first absent |
| Beam Therapeutics Inc | Beam Therapeutics Inc | 2020-06-30 | Removed / first absent |