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VERTEX PHARMACEUTICALS INC / MA (VRTX) Forms 3, 4 and 5: Stock Options

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VERTEX PHARMACEUTICALS INC / MA Forms 3, 4 and 5: Stock Options

Statements of beneficial ownership filed with the SEC by officers, directors and 10% owners: 12 rows in 2026. Transaction codes are the SEC's. Shares and prices are split-adjusted; the as-filed figure is underneath.

  • 2026-05-01: Reporting owner Upadhyay Suketu; Form 4; Security Stock Option (Right to Buy); Transaction A Grant, award or other acquisition pursuant to Rule 16b-3(d).
  • 2026-05-01: Reporting owner Thornberry Nancy; Form 4; Security Stock Option (Right to Buy); Transaction A Grant, award or other acquisition pursuant to Rule 16b-3(d).
  • 2026-05-01: Reporting owner Schneider Jennifer; Form 4; Security Stock Option (Right to Buy); Transaction A Grant, award or other acquisition pursuant to Rule 16b-3(d).
  • 2026-05-01: Reporting owner SACHS BRUCE I; Form 4; Security Stock Option (Right to Buy); Transaction A Grant, award or other acquisition pursuant to Rule 16b-3(d).

VRTX insiders transactions against the stock price

Blue: Split-adjusted close · Orange: Cumulative dividend-reinvested close

$389.00$422.20$458.23$497.34$539.79$585.862025-11-062026-11-06$172.42$220.21$281.24$359.18$458.73$585.862021-11-082026-11-06$68.42$105.12$161.52$248.17$381.30$585.862016-11-072026-11-06$13.86$29.31$61.97$131.03$277.07$585.862006-11-062026-11-06$3.21$9.10$25.77$73.00$206.81$585.861991-07-242026-11-062006-01-17: 1 award or grant at $33.59 close — BRUM LYNNE H2006-01-23: 3 award or grants at $33.46 close — SMITH IAN F, BRUM LYNNE H2006-01-31: 1 award or grant at $35.72 close — BRUM LYNNE H2006-02-02: 9 award or grants at $35.08 close — GARRISON RICHARD C, Hartmann Victor A, BRUM LYNNE H and 6 more2006-02-06: 1 award or grant at $34.30 close — BRUM LYNNE H2006-02-13: 4 award or grants at $34.49 close — BRIMBLECOMBE ROGER W, BRUM LYNNE H2006-02-21: 1 award or grant at $37.39 close — BRUM LYNNE H2006-02-22: 2 award or grants at $38.64 close — SMITH IAN F2006-02-27: 1 award or grant at $44.20 close — BRUM LYNNE H2006-03-02: 1 option exercise at $43.99 close — COLLINSON STUART J2006-03-06: 1 award or grant at $43.42 close — BRUM LYNNE H2006-03-13: 1 award or grant at $36.98 close — BRUM LYNNE H2006-03-20: 1 award or grant at $40.19 close — BRUM LYNNE H2006-03-22: 2 award or grants at $37.85 close — SMITH IAN F2006-03-27: 1 award or grant at $35.56 close — BRUM LYNNE H2006-04-03: 1 award or grant at $35.85 close — BRUM LYNNE H2006-04-03: 1 option exercise at $35.85 close — COLLINSON STUART J2006-04-10: 1 award or grant at $33.72 close — BRUM LYNNE H2006-04-17: 1 award or grant at $35.47 close — BRUM LYNNE H2006-04-24: 3 award or grants at $38.37 close — BRUM LYNNE H, SMITH IAN F2006-05-01: 2 award or grants at $35.65 close — BRUM LYNNE H2006-05-02: 1 option exercise at $34.51 close — COLLINSON STUART J2006-05-08: 2 award or grants at $36.31 close — BRUM LYNNE H2006-05-30: 1 award or grant at $32.62 close — BOGER JOSHUA S2006-06-01: 9 award or grants at $34.35 close — BRANDT ERIC, COLLINSON STUART J, Emmens Matthew and 6 more2006-06-02: 1 option exercise at $34.67 close — COLLINSON STUART J2006-06-13: 1 award or grant at $29.78 close — BOGER JOSHUA S2006-06-27: 1 award or grant at $30.22 close — BOGER JOSHUA S2006-07-03: 1 option exercise at $36.57 close — COLLINSON STUART J2006-07-11: 1 option exercise at $35.84 close — BOGER JOSHUA S2006-07-20: 8 award or grants at $34.99 close — GARRISON RICHARD C, Hartmann Victor A, MUELLER PETER and 5 more2006-07-24: 2 option exercises at $35.05 close — SMITH IAN F2006-07-25: 1 option exercise at $35.60 close — BOGER JOSHUA S2006-08-01: 1 option exercise at $32.51 close — Hartmann Victor A2006-08-02: 1 option exercise at $32.35 close — COLLINSON STUART J2006-08-08: 1 option exercise at $30.59 close — BOGER JOSHUA S2006-08-22: 1 option exercise at $32.71 close — BOGER JOSHUA S2006-08-30: 1 option exercise at $34.98 close — ALAM JOHN J2006-09-05: 1 option exercise at $36.15 close — BOGER JOSHUA S2006-09-06: 1 option exercise at $34.81 close — ALAM JOHN J2006-09-19: 1 option exercise at $32.22 close — BOGER JOSHUA S2006-10-03: 2 option exercises at $33.99 close — BOGER JOSHUA S2006-10-11: 1 option exercise at $35.78 close — ALAM JOHN J2006-10-18: 1 option exercise at $36.17 close — ALAM JOHN J2006-10-23: 2 option exercises at $33.69 close — SMITH IAN F2006-10-30: 1 option exercise at $39.92 close — POWER JOHANNA MESSINA2006-10-31: 1 option exercise at $40.60 close — BOGER JOSHUA S2006-11-01: 1 option exercise at $39.78 close — ALAM JOHN J2006-11-08: 1 option exercise at $41.94 close — ALAM JOHN J2006-11-14: 1 option exercise at $42.69 close — BOGER JOSHUA S2006-11-15: 1 option exercise at $43.96 close — ALAM JOHN J2006-11-16: 1 disposition to the issuer at $44.66 close — MUELLER PETER2006-11-22: 1 option exercise at $44.90 close — ALAM JOHN J2006-11-28: 1 option exercise at $43.82 close — BOGER JOSHUA S2006-11-29: 2 option exercises at $44.89 close — ALAM JOHN J2006-11-30: 1 option exercise at $44.30 close — SANDERS CHARLES A2006-12-01: 1 option exercise at $44.14 close — SANDERS CHARLES A2006-12-04: 1 option exercise at $44.19 close — SANDERS CHARLES A2006-12-05: 2 option exercises at $44.54 close — SANDERS CHARLES A, BOGER JOSHUA S2006-12-06: 3 option exercises at $44.48 close — SANDERS CHARLES A, ALAM JOHN J2006-12-07: 1 option exercise at $43.59 close — SANDERS CHARLES A2006-12-08: 1 option exercise at $43.23 close — SANDERS CHARLES A2006-12-13: 2 option exercises at $38.70 close — ALAM JOHN J2006-12-14: 2 option exercises at $38.71 close — COLLINSON STUART J2006-12-15: 1 award or grant at $38.93 close — SANDERS CHARLES A2006-12-20: 2 option exercises at $37.45 close — ALAM JOHN J2006-12-27: 2 option exercises at $37.39 close — ALAM JOHN J2007-01-03: 3 option exercises at $36.90 close — ALAM JOHN J, Hartmann Victor A2007-01-08: 2 option exercises at $33.55 close — POWER JOHANNA MESSINA2007-01-10: 2 option exercises at $35.37 close — ALAM JOHN J2007-01-16: 1 option exercise at $38.42 close — POWER JOHANNA MESSINA2007-01-17: 2 option exercises at $37.89 close — ALAM JOHN J2007-01-22: 1 option exercise at $35.95 close — POWER JOHANNA MESSINA2007-01-24: 8 award or grants at $36.27 close — GARRISON RICHARD C, Hartmann Victor A, MUELLER PETER and 5 more2007-01-24: 2 option exercises at $36.27 close — ALAM JOHN J2007-01-29: 1 option exercise at $35.31 close — POWER JOHANNA MESSINA2007-01-31: 2 option exercises at $35.35 close — ALAM JOHN J2007-02-05: 2 option exercises at $32.52 close — POWER JOHANNA MESSINA, Hartmann Victor A2007-02-07: 5 option exercises at $33.08 close — ULLIAN ELAINE2007-02-12: 1 option exercise at $32.01 close — POWER JOHANNA MESSINA2007-02-20: 2 option exercises at $31.42 close — POWER JOHANNA MESSINA2007-02-26: 1 option exercise at $31.62 close — POWER JOHANNA MESSINA2007-03-05: 2 option exercises at $28.87 close — Hartmann Victor A, POWER JOHANNA MESSINA2007-03-12: 1 option exercise at $30.40 close — POWER JOHANNA MESSINA2007-03-30: 1 option exercise at $28.04 close — BOGER KENNETH S2007-04-03: 1 option exercise at $28.89 close — Hartmann Victor A2007-04-04: 2 option exercises at $29.85 close — POWER JOHANNA MESSINA2007-04-09: 1 option exercise at $31.56 close — POWER JOHANNA MESSINA2007-04-10: 1 award or grant at $32.12 close — BRIMBLECOMBE ROGER W2007-04-17: 1 option exercise at $31.68 close — POWER JOHANNA MESSINA2007-04-23: 1 option exercise at $31.54 close — POWER JOHANNA MESSINA2007-04-30: 3 option exercises at $30.74 close — POWER JOHANNA MESSINA, BOGER KENNETH S2007-05-03: 1 option exercise at $30.77 close — Hartmann Victor A2007-05-07: 5 option exercises at $30.42 close — POWER JOHANNA MESSINA, ALAM JOHN J, SANDERS CHARLES A2007-05-14: 1 option exercise at $30.42 close — POWER JOHANNA MESSINA2007-05-21: 1 option exercise at $31.61 close — POWER JOHANNA MESSINA2007-05-29: 2 option exercises at $30.51 close — POWER JOHANNA MESSINA, Slater Eve Elizabeth2007-05-31: 1 award or grant at $29.90 close — SANDERS CHARLES A2007-06-01: 9 award or grants at $29.66 close — Emmens Matthew, Slater Eve Elizabeth, COLLINSON STUART J and 6 more2007-06-04: 1 option exercise at $29.47 close — Hartmann Victor A2007-06-08: 3 option exercises at $27.73 close — BOGER JOSHUA S2007-07-12: 8 award or grants at $29.40 close — GARRISON RICHARD C, MUELLER PETER, SMITH IAN F and 5 more2007-07-17: 1 award or grant at $28.90 close — Graves Kurt2007-07-23: 1 award or grant at $29.24 close — Sachdev Amit2007-07-25: 2 option exercises at $32.98 close — POWER JOHANNA MESSINA2007-07-30: 1 option exercise at $32.60 close — POWER JOHANNA MESSINA2007-08-06: 5 option exercises at $35.76 close — POWER JOHANNA MESSINA, ALAM JOHN J2007-08-13: 1 option exercise at $35.95 close — POWER JOHANNA MESSINA2007-08-20: 1 option exercise at $36.80 close — POWER JOHANNA MESSINA2007-08-27: 1 option exercise at $36.89 close — POWER JOHANNA MESSINA2007-09-04: 1 option exercise at $39.56 close — POWER JOHANNA MESSINA2007-09-05: 1 option exercise at $39.98 close — SMITH IAN F2007-09-10: 1 option exercise at $39.85 close — POWER JOHANNA MESSINA2007-09-17: 1 option exercise at $38.39 close — POWER JOHANNA MESSINA2007-09-19: 1 option exercise at $38.68 close — POWER JOHANNA MESSINA2007-09-24: 1 option exercise at $38.65 close — POWER JOHANNA MESSINA2007-10-01: 1 option exercise at $38.98 close — POWER JOHANNA MESSINA2007-10-08: 1 option exercise at $36.59 close — POWER JOHANNA MESSINA2007-10-15: 1 option exercise at $36.08 close — POWER JOHANNA MESSINA2007-10-22: 1 option exercise at $31.82 close — POWER JOHANNA MESSINA2007-10-29: 1 option exercise at $32.94 close — POWER JOHANNA MESSINA2007-11-06: 1 option exercise at $25.05 close — BOGER JOSHUA S2007-11-08: 1 option exercise at $25.56 close — BOGER JOSHUA S2007-11-13: 1 option exercise at $26.23 close — BOGER JOSHUA S2007-11-15: 1 option exercise at $26.12 close — BOGER JOSHUA S2007-11-20: 1 option exercise at $24.57 close — BOGER JOSHUA S2007-11-21: 1 option exercise at $23.54 close — BOGER JOSHUA S2007-11-27: 1 option exercise at $24.22 close — BOGER JOSHUA S2007-11-29: 1 option exercise at $25.10 close — BOGER JOSHUA S2007-12-04: 1 option exercise at $24.82 close — BOGER JOSHUA S2007-12-06: 1 option exercise at $25.91 close — BOGER JOSHUA S2007-12-07: 1 option exercise at $25.49 close — BOGER JOSHUA S2008-01-07: 1 option exercise at $20.94 close — SACHS BRUCE I2008-02-07: 10 award or grants at $19.01 close — Sachdev Amit, Graves Kurt, Kelly Lisa and 7 more2008-02-12: 2 option exercises at $17.14 close — BOGER JOSHUA S2008-05-13: 2 award or grants at $26.92 close — BRIMBLECOMBE ROGER W, SANDERS CHARLES A2008-05-15: 1 award or grant at $27.86 close — SANDERS CHARLES A2008-05-20: 2 award or grants at $27.48 close — BRIMBLECOMBE ROGER W, SANDERS CHARLES A2008-05-27: 2 award or grants at $27.24 close — BRIMBLECOMBE ROGER W, SANDERS CHARLES A2008-06-01: 8 award or grants at $28.63 close — SACHS BRUCE I, Emmens Matthew, BRIMBLECOMBE ROGER W and 5 more2008-06-18: 1 award or grant at $33.20 close — Lewis-Hall Freda C2008-06-19: 2 option exercises at $33.90 close — ALAM JOHN J2008-07-09: 8 option exercises at $33.67 close — SMITH IAN F2008-07-15: 1 option exercise at $32.23 close — MUELLER PETER2008-07-24: 10 award or grants at $31.51 close — Sachdev Amit, Graves Kurt, Kelly Lisa and 7 more2008-07-30: 1 option exercise at $33.18 close — BOGER JOSHUA S2008-08-06: 1 option exercise at $31.54 close — BOGER JOSHUA S2008-08-13: 1 option exercise at $28.87 close — BOGER JOSHUA S2008-08-20: 2 option exercises at $26.32 close — BOGER JOSHUA S, ALAM JOHN J2008-08-27: 2 option exercises at $27.03 close — ALAM JOHN J, BOGER JOSHUA S2008-09-03: 2 option exercises at $26.32 close — ALAM JOHN J, BOGER JOSHUA S2008-09-10: 2 option exercises at $26.94 close — BOGER JOSHUA S, ALAM JOHN J2008-09-17: 1 option exercise at $26.57 close — MUELLER PETER2008-10-01: 1 option exercise at $32.65 close — ALAM JOHN J2008-10-15: 2 option exercises at $24.78 close — MUELLER PETER, BOGER JOSHUA S2008-10-22: 1 option exercise at $22.76 close — BOGER JOSHUA S2008-10-29: 1 option exercise at $22.30 close — BOGER JOSHUA S2008-11-05: 2 option exercises at $27.52 close — BOGER JOSHUA S2008-11-12: 1 option exercise at $26.70 close — BOGER JOSHUA S2008-11-17: 1 option exercise at $26.67 close — MUELLER PETER2008-11-26: 1 option exercise at $24.67 close — BOGER JOSHUA S2008-12-03: 1 option exercise at $23.34 close — BOGER JOSHUA S2008-12-15: 1 option exercise at $25.17 close — MUELLER PETER2009-01-15: 1 option exercise at $30.86 close — MUELLER PETER2009-01-29: 2 option exercises at $33.72 close — BRANDT ERIC2009-02-05: 11 award or grants at $33.96 close — Silva Paul M, Lewis-Hall Freda C, Sachdev Amit and 8 more2009-02-06: 3 option exercises at $35.00 close — SMITH IAN F2009-02-17: 1 option exercise at $33.10 close — MUELLER PETER2009-03-16: 1 option exercise at $27.46 close — MUELLER PETER2009-04-15: 2 option exercises at $27.06 close — SACHS BRUCE I, MUELLER PETER2009-05-04: 1 option exercise at $30.51 close — SANDERS CHARLES A2009-05-11: 1 option exercise at $30.68 close — SANDERS CHARLES A2009-05-15: 1 option exercise at $28.54 close — MUELLER PETER2009-05-18: 1 option exercise at $29.10 close — SANDERS CHARLES A2009-06-01: 7 award or grants at $30.04 close — COLLINSON STUART J, BRIMBLECOMBE ROGER W, BOGER JOSHUA S and 4 more2009-06-03: 1 option exercise at $31.52 close — BOGER JOSHUA S2009-06-10: 1 option exercise at $30.13 close — BOGER JOSHUA S2009-06-15: 1 option exercise at $30.95 close — MUELLER PETER2009-06-17: 2 option exercises at $31.87 close — BOGER JOSHUA S2009-06-24: 1 option exercise at $34.01 close — BOGER JOSHUA S2009-06-26: 8 option exercises at $36.04 close — BOGER KENNETH S2009-07-01: 1 option exercise at $34.56 close — BOGER JOSHUA S2009-07-06: 2 award or grants at $33.92 close — WINGER DENNIS L, LEIDEN JEFFREY M2009-07-09: 1 option exercise at $33.39 close — BOGER JOSHUA S2009-07-15: 3 option exercises at $32.98 close — BOGER JOSHUA S, MUELLER PETER2009-07-16: 7 award or grants at $33.23 close — Silva Paul M, Sachdev Amit, Graves Kurt and 4 more2009-07-28: 3 option exercises at $36.09 close — BOGER KENNETH S2009-07-29: 1 option exercise at $36.23 close — BOGER JOSHUA S2009-08-03: 2 option exercises at $36.48 close — BOGER KENNETH S2009-08-05: 1 option exercise at $36.95 close — BOGER JOSHUA S2009-08-12: 1 option exercise at $33.99 close — BOGER JOSHUA S2009-08-19: 1 option exercise at $36.09 close — BOGER JOSHUA S2009-08-25: 1 option exercise at $36.74 close — BOGER JOSHUA S2009-09-01: 1 option exercise at $36.87 close — BOGER JOSHUA S2009-09-09: 1 option exercise at $36.92 close — BOGER JOSHUA S2009-09-16: 1 option exercise at $37.20 close — BOGER JOSHUA S2009-09-23: 1 option exercise at $36.50 close — BOGER JOSHUA S2009-09-30: 1 option exercise at $37.90 close — BOGER JOSHUA S2009-10-07: 1 option exercise at $33.75 close — BOGER JOSHUA S2009-10-14: 1 option exercise at $34.32 close — BOGER JOSHUA S2009-10-21: 2 option exercises at $32.90 close — BOGER JOSHUA S2009-10-22: 5 award or grants at $32.91 close — SMITH IAN F, Sachdev Amit, MUELLER PETER and 2 more2009-11-04: 1 option exercise at $36.89 close — BOGER JOSHUA S2009-11-11: 1 option exercise at $41.10 close — BOGER JOSHUA S2009-11-18: 1 option exercise at $39.51 close — BOGER JOSHUA S2009-11-25: 1 option exercise at $39.38 close — BOGER JOSHUA S2009-12-04: 1 option exercise at $39.63 close — MUELLER PETER2009-12-09: 2 award or grants at $40.18 close — Wysenski Nancy2010-01-15: 1 option exercise at $40.21 close — MUELLER PETER2010-02-04: 7 award or grants at $38.42 close — Sachdev Amit, Silva Paul M, Emmens Matthew and 4 more2010-02-16: 1 option exercise at $38.68 close — MUELLER PETER2010-03-15: 2 option exercises at $43.24 close — MUELLER PETER, BRIMBLECOMBE ROGER W2010-04-15: 1 option exercise at $39.66 close — MUELLER PETER2010-05-17: 1 option exercise at $37.56 close — MUELLER PETER2010-06-01: 8 award or grants at $34.19 close — LEIDEN JEFFREY M, WINGER DENNIS L, COLLINSON STUART J and 5 more2010-06-15: 1 option exercise at $35.09 close — MUELLER PETER2010-07-02: 4 option exercises at $32.22 close — SACHS BRUCE I2010-07-09: 1 award or grant at $34.18 close — Riley Wayne Joseph2010-07-14: 8 award or grants at $34.10 close — MUELLER PETER, Silva Paul M, Sachdev Amit and 5 more2010-07-15: 1 option exercise at $33.77 close — MUELLER PETER2010-08-16: 1 option exercise at $36.30 close — MUELLER PETER2010-09-15: 1 option exercise at $37.24 close — MUELLER PETER2010-10-15: 1 option exercise at $36.03 close — MUELLER PETER2010-11-15: 1 option exercise at $34.56 close — MUELLER PETER2010-12-15: 1 award or grant at $34.38 close — LEIDEN JEFFREY M2011-01-18: 1 option exercise at $40.00 close — Sachdev Amit2011-02-03: 9 award or grants at $38.80 close — Stamoulis Christiana, Sachdev Amit, Silva Paul M and 6 more2011-02-23: 1 option exercise at $43.97 close — Sachdev Amit2011-02-28: 2 option exercises at $46.67 close — Kelly Lisa, Sachdev Amit2011-03-02: 1 option exercise at $47.28 close — Kelly Lisa2011-03-03: 2 option exercises at $49.95 close — Kelly Lisa, Sachdev Amit2011-03-23: 1 option exercise at $46.08 close — ULLIAN ELAINE2011-04-11: 2 option exercises at $48.22 close — MUELLER PETER2011-04-15: 1 option exercise at $48.02 close — MUELLER PETER2011-04-25: 2 option exercises at $48.04 close — MUELLER PETER, Kelly Lisa2011-04-27: 1 option exercise at $55.54 close — Kelly Lisa2011-05-02: 1 option exercise at $55.05 close — BOGER KENNETH S2011-05-09: 1 option exercise at $57.65 close — Kelly Lisa2011-05-11: 1 option exercise at $56.25 close — BOGER JOSHUA S2011-05-12: 1 award or grant at $58.01 close — MCGLYNN MARGARET G2011-05-16: 1 option exercise at $57.27 close — MUELLER PETER2011-05-17: 1 award or grant at $56.51 close — Kearney Terrence C2011-05-18: 1 option exercise at $55.42 close — BOGER JOSHUA S2011-05-25: 1 option exercise at $55.57 close — BOGER JOSHUA S2011-05-27: 1 option exercise at $53.54 close — SACHS BRUCE I2011-06-01: 8 award or grants at $53.02 close — WINGER DENNIS L, ULLIAN ELAINE, SACHS BRUCE I and 5 more2011-06-01: 2 option exercises at $53.02 close — BOGER KENNETH S, BOGER JOSHUA S2011-06-08: 2 option exercises at $53.14 close — BOGER KENNETH S, BOGER JOSHUA S2011-06-15: 2 option exercises at $46.42 close — MUELLER PETER, BOGER JOSHUA S2011-06-22: 1 option exercise at $47.21 close — BOGER JOSHUA S2011-06-28: 1 option exercise at $50.73 close — BOGER KENNETH S2011-06-29: 2 option exercises at $52.27 close — BOGER KENNETH S, BOGER JOSHUA S2011-07-06: 2 option exercises at $50.17 close — BOGER KENNETH S, BOGER JOSHUA S2011-07-12: 1 option exercise at $51.41 close — Kelly Lisa2011-07-13: 10 award or grants at $51.49 close — Wysenski Nancy, Stamoulis Christiana, SMITH IAN F and 6 more2011-07-13: 3 option exercises at $51.49 close — BOGER KENNETH S, BOGER JOSHUA S2011-07-15: 1 option exercise at $50.68 close — MUELLER PETER2011-07-20: 1 option exercise at $50.20 close — BOGER JOSHUA S2011-07-27: 1 option exercise at $47.92 close — BOGER JOSHUA S2011-07-29: 2 option exercises at $51.86 close — Kelly Lisa, BOGER KENNETH S2011-08-03: 1 option exercise at $47.90 close — BOGER JOSHUA S2011-08-10: 1 option exercise at $41.78 close — BOGER JOSHUA S2011-08-17: 1 option exercise at $46.65 close — BOGER JOSHUA S2011-08-24: 1 option exercise at $46.53 close — BOGER JOSHUA S2011-08-29: 2 option exercises at $43.95 close — MUELLER PETER2011-08-31: 3 option exercises at $45.27 close — Kelly Lisa, BOGER JOSHUA S2011-09-07: 1 option exercise at $46.94 close — BOGER JOSHUA S2011-09-13: 1 option exercise at $50.21 close — BOGER KENNETH S2011-09-14: 1 option exercise at $50.55 close — BOGER JOSHUA S2011-09-15: 1 option exercise at $50.12 close — MUELLER PETER2011-09-20: 2 option exercises at $52.05 close — MUELLER PETER2011-09-21: 1 option exercise at $53.18 close — BOGER JOSHUA S2011-09-28: 1 option exercise at $45.69 close — BOGER JOSHUA S2011-10-05: 1 option exercise at $45.12 close — BOGER JOSHUA S2011-10-11: 1 option exercise at $39.95 close — BOGER JOSHUA S2011-10-19: 1 option exercise at $40.17 close — BOGER JOSHUA S2011-10-26: 1 option exercise at $42.89 close — BOGER JOSHUA S2011-11-02: 1 option exercise at $36.90 close — BOGER JOSHUA S2011-11-09: 1 option exercise at $30.86 close — BOGER JOSHUA S2011-11-16: 1 option exercise at $29.26 close — BOGER JOSHUA S2011-11-23: 1 option exercise at $26.94 close — BOGER JOSHUA S2011-12-01: 1 option exercise at $29.39 close — BOGER JOSHUA S2011-12-06: 1 option exercise at $29.66 close — BOGER JOSHUA S2011-12-14: 1 award or grant at $30.54 close — LEIDEN JEFFREY M2012-02-02: 9 award or grants at $38.38 close — Wysenski Nancy, Stamoulis Christiana, SMITH IAN F and 6 more2012-03-09: 2 option exercises at $41.79 close — WINGER DENNIS L2012-03-28: 1 option exercise at $40.44 close — BOGER JOSHUA S2012-03-30: 1 option exercise at $41.01 close — Sachdev Amit2012-04-04: 1 option exercise at $40.57 close — BOGER JOSHUA S2012-04-11: 1 option exercise at $37.03 close — BOGER JOSHUA S2012-04-18: 1 option exercise at $35.56 close — BOGER JOSHUA S2012-04-25: 1 option exercise at $37.67 close — BOGER JOSHUA S2012-05-02: 1 option exercise at $38.36 close — BOGER JOSHUA S2012-05-07: 10 option exercises at $58.12 close — Wysenski Nancy, Sachdev Amit, MUELLER PETER and 1 more2012-05-08: 3 option exercises at $64.16 close — Wysenski Nancy2012-05-09: 12 option exercises at $60.35 close — Silva Paul M, BOGER JOSHUA S, ULLIAN ELAINE2012-05-14: 4 option exercises at $64.70 close — Wysenski Nancy2012-05-15: 1 option exercise at $63.38 close — MUELLER PETER2012-05-16: 1 option exercise at $62.61 close — BOGER JOSHUA S2012-05-23: 1 option exercise at $63.94 close — BOGER JOSHUA S2012-05-24: 1 award or grant at $64.09 close — ALTSHULER DAVID2012-05-30: 1 option exercise at $60.18 close — BOGER JOSHUA S2012-06-01: 8 award or grants at $59.56 close — ULLIAN ELAINE, SACHS BRUCE I, Riley Wayne Joseph and 5 more2012-06-06: 1 option exercise at $57.84 close — BOGER JOSHUA S2012-06-11: 1 award or grant at $54.90 close — Horton Kenneth L2012-06-13: 1 option exercise at $55.46 close — BOGER JOSHUA S2012-06-15: 1 option exercise at $56.54 close — MUELLER PETER2012-06-20: 1 option exercise at $59.15 close — BOGER JOSHUA S2012-06-27: 1 option exercise at $61.11 close — BOGER JOSHUA S2012-07-05: 1 option exercise at $55.51 close — BOGER JOSHUA S2012-07-11: 1 option exercise at $52.76 close — BOGER JOSHUA S2012-07-16: 1 option exercise at $52.40 close — MUELLER PETER2012-07-18: 1 option exercise at $53.61 close — BOGER JOSHUA S2012-07-25: 8 award or grants at $49.08 close — Pace Megan E, Stamoulis Christiana, SMITH IAN F and 5 more2012-07-25: 1 option exercise at $49.08 close — BOGER JOSHUA S2012-08-01: 1 option exercise at $49.16 close — BOGER JOSHUA S2012-08-08: 1 option exercise at $50.81 close — BOGER JOSHUA S2012-08-15: 2 option exercises at $54.42 close — MUELLER PETER, BOGER JOSHUA S2012-08-16: 1 option exercise at $54.48 close — Kelly Lisa2012-08-22: 1 option exercise at $54.67 close — BOGER JOSHUA S2012-08-29: 1 option exercise at $53.32 close — BOGER JOSHUA S2012-09-04: 1 award or grant at $54.53 close — Arbuckle Stuart A2012-09-05: 1 option exercise at $54.99 close — BOGER JOSHUA S2012-09-12: 1 option exercise at $55.74 close — BOGER JOSHUA S2012-09-13: 2 option exercises at $56.21 close — Sachdev Amit2012-09-14: 1 award or grant at $58.08 close — Lee Yuchun2012-09-14: 1 option exercise at $58.08 close — Sachdev Amit2012-09-17: 1 option exercise at $57.54 close — MUELLER PETER2012-09-19: 3 option exercises at $57.90 close — Kelly Lisa, BOGER JOSHUA S2012-09-21: 1 option exercise at $59.04 close — Sachdev Amit2012-09-26: 1 option exercise at $54.77 close — BOGER JOSHUA S2012-10-03: 1 option exercise at $57.76 close — BOGER JOSHUA S2012-10-08: 3 option exercises at $58.49 close — SMITH IAN F2012-10-10: 1 option exercise at $57.00 close — BOGER JOSHUA S2012-10-11: 2 option exercises at $56.88 close — SMITH IAN F2012-10-15: 1 option exercise at $53.24 close — MUELLER PETER2012-10-17: 1 option exercise at $53.95 close — BOGER JOSHUA S2012-10-24: 1 option exercise at $49.50 close — BOGER JOSHUA S2012-10-31: 1 option exercise at $48.28 close — BOGER JOSHUA S2012-11-07: 1 option exercise at $45.53 close — BOGER JOSHUA S2012-11-14: 1 option exercise at $42.16 close — BOGER JOSHUA S2012-11-21: 1 option exercise at $41.11 close — BOGER JOSHUA S2012-11-28: 1 option exercise at $39.53 close — BOGER JOSHUA S2012-12-05: 1 option exercise at $39.18 close — BOGER JOSHUA S2012-12-12: 1 option exercise at $42.25 close — BOGER JOSHUA S2012-12-19: 1 option exercise at $43.02 close — BOGER JOSHUA S2012-12-26: 1 option exercise at $41.75 close — BOGER JOSHUA S2013-01-02: 1 option exercise at $43.65 close — BOGER JOSHUA S2013-02-05: 10 award or grants at $45.60 close — Stamoulis Christiana, SMITH IAN F, Silva Paul M and 7 more2013-04-19: 22 option exercises at $85.60 close — Silva Paul M, SMITH IAN F2013-04-25: 1 option exercise at $80.32 close — Silva Paul M2013-04-29: 2 option exercises at $78.33 close — Stamoulis Christiana2013-04-30: 1 option exercise at $76.82 close — Stamoulis Christiana2013-05-02: 1 option exercise at $77.72 close — Silva Paul M2013-05-03: 3 option exercises at $75.99 close — ULLIAN ELAINE, Silva Paul M2013-05-06: 1 option exercise at $77.25 close — Silva Paul M2013-05-15: 1 option exercise at $79.42 close — BOGER JOSHUA S2013-05-22: 1 option exercise at $78.43 close — BOGER JOSHUA S2013-05-30: 1 option exercise at $83.14 close — BOGER JOSHUA S2013-06-01: 8 award or grants at $80.33 close — ULLIAN ELAINE, SACHS BRUCE I, Riley Wayne Joseph and 5 more2013-06-05: 1 option exercise at $76.95 close — BOGER JOSHUA S2013-06-12: 1 option exercise at $80.23 close — BOGER JOSHUA S2013-06-19: 1 option exercise at $77.87 close — BOGER JOSHUA S2013-06-26: 1 option exercise at $80.32 close — BOGER JOSHUA S2013-07-02: 3 option exercises at $79.52 close — MUELLER PETER2013-07-03: 1 option exercise at $80.63 close — BOGER JOSHUA S2013-07-05: 3 option exercises at $82.43 close — Sachdev Amit, Stamoulis Christiana2013-07-08: 2 option exercises at $80.38 close — Pace Megan E2013-07-11: 3 option exercises at $84.70 close — Sachdev Amit, Pace Megan E, BOGER JOSHUA S2013-07-12: 3 option exercises at $87.79 close — Sachdev Amit, Pace Megan E2013-07-15: 4 option exercises at $86.75 close — Stamoulis Christiana, Silva Paul M, MUELLER PETER2013-07-16: 1 option exercise at $85.49 close — Silva Paul M2013-07-18: 1 option exercise at $86.79 close — BOGER JOSHUA S2013-07-19: 2 option exercises at $88.51 close — Sachdev Amit2013-07-24: 1 option exercise at $85.26 close — BOGER JOSHUA S2013-07-25: 1 option exercise at $87.62 close — Silva Paul M2013-07-29: 1 option exercise at $79.66 close — Riley Wayne Joseph2013-07-30: 9 award or grants at $81.91 close — Stamoulis Christiana, SMITH IAN F, Silva Paul M and 6 more2013-07-31: 1 option exercise at $79.80 close — BOGER JOSHUA S2013-08-02: 1 option exercise at $79.44 close — Silva Paul M2013-08-05: 2 option exercises at $78.99 close — Silva Paul M2013-08-07: 1 option exercise at $78.05 close — BOGER JOSHUA S2013-08-14: 1 option exercise at $78.25 close — BOGER JOSHUA S2013-08-15: 1 option exercise at $76.96 close — MUELLER PETER2013-08-21: 1 option exercise at $76.35 close — BOGER JOSHUA S2013-08-28: 1 option exercise at $75.94 close — BOGER JOSHUA S2013-09-04: 1 option exercise at $78.30 close — BOGER JOSHUA S2013-09-11: 1 option exercise at $79.81 close — BOGER JOSHUA S2013-09-16: 1 option exercise at $76.18 close — MUELLER PETER2013-09-18: 1 option exercise at $77.11 close — BOGER JOSHUA S2013-09-25: 1 option exercise at $74.67 close — BOGER JOSHUA S2013-10-02: 1 option exercise at $76.74 close — BOGER JOSHUA S2013-10-09: 1 option exercise at $70.15 close — BOGER JOSHUA S2013-10-14: 2 option exercises at $73.71 close — Silva Paul M2013-10-15: 1 option exercise at $73.35 close — MUELLER PETER2013-10-16: 1 option exercise at $75.46 close — BOGER JOSHUA S2013-10-23: 1 option exercise at $75.61 close — BOGER JOSHUA S2013-10-25: 1 option exercise at $76.83 close — Silva Paul M2013-10-29: 2 option exercises at $76.09 close — Connolly Thomas, BOGER JOSHUA S2013-11-04: 3 option exercises at $66.21 close — Silva Paul M2013-11-05: 2 option exercises at $65.38 close — BOGER JOSHUA S, Connolly Thomas2013-11-12: 1 option exercise at $60.18 close — BOGER JOSHUA S2013-11-15: 2 option exercises at $63.39 close — MUELLER PETER2013-11-19: 1 option exercise at $62.38 close — BOGER JOSHUA S2013-11-25: 1 option exercise at $67.96 close — BOGER JOSHUA S2013-12-04: 2 option exercises at $67.33 close — Connolly Thomas, BOGER JOSHUA S2013-12-16: 1 option exercise at $64.76 close — MUELLER PETER2014-01-15: 1 option exercise at $78.77 close — MUELLER PETER2014-01-16: 1 option exercise at $81.00 close — LEIDEN JEFFREY M2014-02-05: 9 award or grants at $77.41 close — SMITH IAN F, Silva Paul M, Sachdev Amit and 6 more2014-02-05: 1 option exercise at $77.41 close — Connolly Thomas2014-02-18: 1 option exercise at $82.00 close — MUELLER PETER2014-03-17: 1 option exercise at $77.70 close — MUELLER PETER2014-04-09: 1 option exercise at $69.95 close — ULLIAN ELAINE2014-04-15: 2 option exercises at $63.25 close — MUELLER PETER2014-05-07: 1 award or grant at $65.17 close — YOUNG WILLIAM D2014-05-14: 1 option exercise at $67.69 close — MUELLER PETER2014-06-01: 9 award or grants at $72.26 close — YOUNG WILLIAM D, ULLIAN ELAINE, SACHS BRUCE I and 6 more2014-06-09: 1 option exercise at $74.61 close — ULLIAN ELAINE2014-06-16: 1 option exercise at $67.12 close — MUELLER PETER2014-06-24: 6 option exercises at $93.53 close — Sachdev Amit, Riley Wayne Joseph, Pace Megan E2014-07-01: 2 option exercises at $95.85 close — ULLIAN ELAINE, Horton Kenneth L2014-07-15: 9 award or grants at $96.53 close — SMITH IAN F, Silva Paul M, Sachdev Amit and 6 more2014-07-15: 1 option exercise at $96.53 close — Riley Wayne Joseph2014-07-30: 1 option exercise at $92.01 close — BOGER JOSHUA S2014-07-31: 1 option exercise at $88.91 close — ALTSHULER DAVID2014-08-06: 1 option exercise at $86.81 close — BOGER JOSHUA S2014-08-13: 1 option exercise at $88.75 close — BOGER JOSHUA S2014-08-15: 1 option exercise at $90.88 close — Riley Wayne Joseph2014-08-20: 1 option exercise at $91.30 close — BOGER JOSHUA S2014-08-27: 1 option exercise at $93.03 close — BOGER JOSHUA S2014-09-03: 1 option exercise at $92.82 close — BOGER JOSHUA S2014-09-05: 1 option exercise at $95.04 close — ALTSHULER DAVID2014-09-10: 1 option exercise at $94.74 close — BOGER JOSHUA S2014-09-17: 1 option exercise at $94.50 close — BOGER JOSHUA S2014-09-19: 10 option exercises at $103.75 close — Silva Paul M, Arbuckle Stuart A, ALTSHULER DAVID2014-09-24: 2 option exercises at $111.98 close — ALTSHULER DAVID, BOGER JOSHUA S2014-09-29: 1 option exercise at $113.90 close — ALTSHULER DAVID2014-09-30: 26 option exercises at $112.31 close — LEIDEN JEFFREY M, Horton Kenneth L, Pace Megan E and 3 more2014-10-01: 3 option exercises at $107.25 close — ULLIAN ELAINE, ALTSHULER DAVID, BOGER JOSHUA S2014-10-06: 1 option exercise at $105.76 close — ALTSHULER DAVID2014-10-07: 1 option exercise at $102.83 close — Chodakewitz Jeffrey2014-10-13: 1 option exercise at $105.91 close — Silva Paul M2014-10-15: 2 option exercises at $101.10 close — BOGER JOSHUA S2014-10-21: 1 option exercise at $108.16 close — Riley Wayne Joseph2014-10-22: 3 option exercises at $106.17 close — BOGER JOSHUA S2014-10-27: 1 option exercise at $111.59 close — Silva Paul M2014-10-28: 3 option exercises at $114.07 close — Chodakewitz Jeffrey, ALTSHULER DAVID, Sachdev Amit2014-10-29: 3 option exercises at $109.91 close — BOGER JOSHUA S2014-11-03: 3 option exercises at $112.98 close — SACHS BRUCE I, Silva Paul M2014-11-04: 1 option exercise at $114.10 close — SACHS BRUCE I2014-11-05: 7 option exercises at $111.59 close — Silva Paul M, Connolly Thomas, BOGER JOSHUA S and 2 more2014-11-06: 1 option exercise at $117.29 close — SACHS BRUCE I2014-11-12: 3 option exercises at $116.68 close — BOGER JOSHUA S2014-11-19: 3 option exercises at $112.80 close — BOGER JOSHUA S2014-11-26: 3 option exercises at $115.39 close — BOGER JOSHUA S2014-11-28: 6 option exercises at $117.88 close — Silva Paul M, SACHS BRUCE I, Sachdev Amit and 1 more2014-12-03: 3 option exercises at $120.18 close — BOGER JOSHUA S2014-12-04: 1 option exercise at $118.71 close — Connolly Thomas2014-12-10: 3 option exercises at $117.20 close — BOGER JOSHUA S2014-12-17: 3 option exercises at $111.85 close — BOGER JOSHUA S2014-12-22: 3 option exercises at $116.68 close — BOGER JOSHUA S2014-12-31: 3 option exercises at $118.80 close — BOGER JOSHUA S2015-01-02: 2 option exercises at $123.07 close — ULLIAN ELAINE, Chodakewitz Jeffrey2015-01-07: 3 option exercises at $120.66 close — BOGER JOSHUA S2015-01-09: 3 option exercises at $122.21 close — Sachdev Amit, Riley Wayne Joseph, SACHS BRUCE I2015-01-13: 1 option exercise at $120.60 close — Silva Paul M2015-01-14: 3 option exercises at $120.38 close — BOGER JOSHUA S2015-01-20: 1 option exercise at $124.74 close — SACHS BRUCE I2015-01-21: 3 option exercises at $125.09 close — BOGER JOSHUA S2015-01-26: 1 option exercise at $125.12 close — Silva Paul M2015-01-28: 3 option exercises at $121.26 close — BOGER JOSHUA S2015-02-02: 1 option exercise at $111.18 close — Silva Paul M2015-02-03: 6 award or grants at $108.72 close — Silva Paul M, Sachdev Amit, LEIDEN JEFFREY M and 3 more2015-02-03: 1 option exercise at $108.72 close — Silva Paul M2015-02-04: 2 option exercises at $109.27 close — BOGER JOSHUA S2015-02-05: 1 option exercise at $111.59 close — Silva Paul M2015-02-11: 2 option exercises at $108.62 close — BOGER JOSHUA S2015-02-18: 2 option exercises at $113.57 close — BOGER JOSHUA S2015-02-23: 2 option exercises at $117.12 close — Silva Paul M2015-02-25: 2 option exercises at $118.84 close — BOGER JOSHUA S2015-03-04: 2 option exercises at $120.05 close — BOGER JOSHUA S2015-03-11: 4 option exercises at $122.64 close — BOGER JOSHUA S2015-03-18: 3 option exercises at $129.79 close — SACHS BRUCE I, Sachdev Amit2015-03-20: 4 option exercises at $131.00 close — SACHS BRUCE I, Sachdev Amit, Riley Wayne Joseph2015-03-25: 2 option exercises at $118.64 close — BOGER JOSHUA S2015-04-01: 2 option exercises at $116.43 close — BOGER JOSHUA S2015-04-02: 1 option exercise at $117.23 close — Chodakewitz Jeffrey2015-04-06: 1 award or grant at $118.25 close — MCGLYNN MARGARET G2015-04-08: 2 option exercises at $123.79 close — BOGER JOSHUA S2015-04-13: 1 option exercise at $127.81 close — Silva Paul M2015-04-15: 2 option exercises at $129.20 close — BOGER JOSHUA S2015-04-22: 2 option exercises at $132.85 close — BOGER JOSHUA S2015-04-27: 7 option exercises at $127.88 close — Arbuckle Stuart A, Kearney Terrence C, Silva Paul M2015-04-29: 2 option exercises at $123.76 close — BOGER JOSHUA S2015-04-30: 1 option exercise at $123.28 close — Silva Paul M2015-05-04: 1 option exercise at $126.30 close — Silva Paul M2015-05-05: 2 option exercises at $122.15 close — Silva Paul M2015-05-06: 2 option exercises at $122.93 close — BOGER JOSHUA S2015-05-13: 2 option exercises at $125.52 close — BOGER JOSHUA S2015-05-19: 1 option exercise at $128.31 close — Kearney Terrence C2015-05-20: 2 option exercises at $126.75 close — BOGER JOSHUA S2015-05-27: 2 option exercises at $127.80 close — BOGER JOSHUA S2015-06-01: 8 award or grants at $126.80 close — YOUNG WILLIAM D, ULLIAN ELAINE, SACHS BRUCE I and 5 more2015-06-01: 2 option exercises at $126.80 close — MCGLYNN MARGARET G2015-06-03: 2 option exercises at $126.92 close — BOGER JOSHUA S2015-06-04: 1 award or grant at $126.94 close — Bhatia Sangeeta N.2015-06-10: 2 option exercises at $125.18 close — BOGER JOSHUA S2015-06-17: 2 option exercises at $124.05 close — BOGER JOSHUA S2015-06-24: 2 option exercises at $129.59 close — BOGER JOSHUA S2015-07-01: 2 option exercises at $126.19 close — BOGER JOSHUA S2015-07-02: 1 option exercise at $131.26 close — Chodakewitz Jeffrey2015-07-08: 2 option exercises at $121.54 close — BOGER JOSHUA S2015-07-13: 1 option exercise at $124.24 close — Silva Paul M2015-07-15: 2 option exercises at $133.53 close — BOGER JOSHUA S2015-07-21: 7 award or grants at $130.97 close — SMITH IAN F, Silva Paul M, Sachdev Amit and 4 more2015-07-22: 1 option exercise at $131.02 close — BOGER JOSHUA S2015-07-27: 1 option exercise at $123.23 close — Silva Paul M2015-07-29: 1 option exercise at $125.62 close — BOGER JOSHUA S2015-07-30: 1 option exercise at $135.46 close — Silva Paul M2015-08-03: 1 option exercise at $136.99 close — MCGLYNN MARGARET G2015-08-04: 1 option exercise at $140.30 close — SACHS BRUCE I2015-08-05: 3 option exercises at $141.22 close — BOGER JOSHUA S, Arbuckle Stuart A2015-08-12: 1 option exercise at $137.64 close — BOGER JOSHUA S2015-08-19: 1 option exercise at $141.48 close — BOGER JOSHUA S2015-08-26: 1 option exercise at $130.11 close — BOGER JOSHUA S2015-09-01: 1 award or grant at $124.04 close — Lee Yuchun2015-09-02: 1 option exercise at $129.00 close — BOGER JOSHUA S2015-09-04: 1 option exercise at $126.99 close — Arbuckle Stuart A2015-09-09: 1 option exercise at $129.95 close — BOGER JOSHUA S2015-09-16: 1 option exercise at $133.66 close — BOGER JOSHUA S2015-09-23: 1 option exercise at $111.86 close — BOGER JOSHUA S2015-09-30: 1 option exercise at $104.14 close — BOGER JOSHUA S2015-10-01: 1 option exercise at $107.23 close — Lee Yuchun2015-10-02: 1 option exercise at $115.18 close — ULLIAN ELAINE2015-10-07: 1 option exercise at $109.40 close — BOGER JOSHUA S2015-10-14: 1 option exercise at $113.30 close — BOGER JOSHUA S2015-10-21: 1 option exercise at $109.62 close — BOGER JOSHUA S2015-10-28: 1 option exercise at $120.10 close — BOGER JOSHUA S2015-11-02: 2 option exercises at $126.94 close — ULLIAN ELAINE, Lee Yuchun2015-11-04: 1 option exercise at $124.90 close — BOGER JOSHUA S2015-11-05: 2 option exercises at $121.91 close — Arbuckle Stuart A2015-11-11: 1 option exercise at $118.20 close — BOGER JOSHUA S2015-11-16: 1 option exercise at $125.28 close — Arbuckle Stuart A2015-11-18: 5 option exercises at $133.26 close — Chodakewitz Jeffrey, MCGLYNN MARGARET G, BOGER JOSHUA S and 1 more2015-11-23: 1 option exercise at $132.29 close — BOGER JOSHUA S2015-12-01: 3 option exercises at $130.36 close — ULLIAN ELAINE, Lee Yuchun, ALTSHULER DAVID2015-12-02: 1 option exercise at $130.41 close — BOGER JOSHUA S2015-12-04: 1 option exercise at $125.17 close — Arbuckle Stuart A2015-12-09: 1 option exercise at $120.63 close — BOGER JOSHUA S2015-12-16: 1 option exercise at $118.53 close — BOGER JOSHUA S2015-12-21: 1 option exercise at $120.56 close — BOGER JOSHUA S2015-12-30: 1 option exercise at $126.40 close — BOGER JOSHUA S2016-01-04: 1 award or grant at $122.89 close — Parini Michael2016-01-04: 1 option exercise at $122.89 close — Lee Yuchun2016-01-06: 1 option exercise at $122.23 close — BOGER JOSHUA S2016-01-11: 4 gifts at $103.95 close — LEIDEN JEFFREY M2016-01-13: 1 option exercise at $96.37 close — BOGER JOSHUA S2016-01-20: 1 option exercise at $96.99 close — BOGER JOSHUA S2016-01-27: 1 option exercise at $92.50 close — BOGER JOSHUA S2016-02-02: 6 award or grants at $90.98 close — SMITH IAN F, Silva Paul M, Sachdev Amit and 3 more2016-02-03: 1 option exercise at $93.88 close — BOGER JOSHUA S2016-02-10: 1 option exercise at $81.73 close — BOGER JOSHUA S2016-02-17: 1 option exercise at $88.25 close — BOGER JOSHUA S2016-02-24: 1 option exercise at $86.77 close — BOGER JOSHUA S2016-03-02: 1 option exercise at $92.52 close — BOGER JOSHUA S2016-03-09: 1 option exercise at $84.63 close — BOGER JOSHUA S2016-03-16: 1 option exercise at $79.30 close — BOGER JOSHUA S2016-03-23: 1 option exercise at $80.15 close — BOGER JOSHUA S2016-03-30: 1 option exercise at $78.40 close — BOGER JOSHUA S2016-04-06: 1 option exercise at $91.31 close — BOGER JOSHUA S2016-04-13: 1 option exercise at $85.18 close — BOGER JOSHUA S2016-04-20: 1 option exercise at $84.11 close — BOGER JOSHUA S2016-04-26: 1 option exercise at $84.14 close — Parini Michael2016-04-27: 1 option exercise at $84.50 close — BOGER JOSHUA S2016-05-04: 1 option exercise at $80.63 close — BOGER JOSHUA S2016-05-11: 1 option exercise at $83.63 close — BOGER JOSHUA S2016-05-18: 1 option exercise at $81.71 close — BOGER JOSHUA S2016-05-25: 1 option exercise at $89.56 close — BOGER JOSHUA S2016-06-01: 8 award or grants at $93.90 close — BOGER JOSHUA S, YOUNG WILLIAM D, ULLIAN ELAINE and 5 more2016-06-01: 1 option exercise at $93.90 close — BOGER JOSHUA S2016-06-08: 1 option exercise at $94.59 close — BOGER JOSHUA S2016-06-15: 1 option exercise at $90.84 close — BOGER JOSHUA S2016-06-22: 1 option exercise at $85.22 close — BOGER JOSHUA S2016-06-29: 1 option exercise at $85.00 close — BOGER JOSHUA S2016-07-06: 1 option exercise at $89.66 close — BOGER JOSHUA S2016-07-12: 2 award or grants at $89.63 close — Silva Paul M, Parini Michael2016-07-13: 1 option exercise at $87.78 close — BOGER JOSHUA S2016-07-20: 1 option exercise at $91.15 close — BOGER JOSHUA S2016-07-27: 1 option exercise at $96.01 close — BOGER JOSHUA S2016-08-03: 1 option exercise at $100.44 close — BOGER JOSHUA S2016-08-10: 1 option exercise at $99.70 close — BOGER JOSHUA S2016-08-17: 1 option exercise at $99.89 close — BOGER JOSHUA S2016-08-24: 1 option exercise at $96.71 close — BOGER JOSHUA S2016-08-31: 1 option exercise at $94.51 close — BOGER JOSHUA S2016-09-07: 1 option exercise at $95.60 close — BOGER JOSHUA S2016-09-14: 1 option exercise at $90.12 close — BOGER JOSHUA S2016-09-21: 1 option exercise at $91.82 close — BOGER JOSHUA S2016-09-28: 1 option exercise at $88.84 close — BOGER JOSHUA S2016-10-05: 1 option exercise at $87.65 close — BOGER JOSHUA S2016-10-12: 1 option exercise at $80.15 close — BOGER JOSHUA S2016-10-19: 1 option exercise at $81.83 close — BOGER JOSHUA S2016-10-26: 1 option exercise at $78.71 close — BOGER JOSHUA S2016-11-02: 1 option exercise at $78.00 close — BOGER JOSHUA S2016-11-09: 2 option exercises at $92.88 close — BOGER JOSHUA S, Silva Paul M2016-11-10: 1 option exercise at $95.36 close — Silva Paul M2016-11-16: 1 option exercise at $90.47 close — BOGER JOSHUA S2016-11-23: 1 option exercise at $87.34 close — BOGER JOSHUA S2016-11-30: 1 option exercise at $81.61 close — BOGER JOSHUA S2016-12-07: 1 option exercise at $75.32 close — BOGER JOSHUA S2016-12-14: 1 option exercise at $78.33 close — BOGER JOSHUA S2016-12-21: 1 option exercise at $72.60 close — BOGER JOSHUA S2016-12-29: 1 option exercise at $74.44 close — BOGER JOSHUA S2017-01-04: 1 option exercise at $77.05 close — BOGER JOSHUA S2017-01-11: 1 option exercise at $81.93 close — BOGER JOSHUA S2017-02-03: 7 award or grants at $86.73 close — Silva Paul M, Parini Michael, ALTSHULER DAVID and 4 more2017-03-29: 6 option exercises at $42.63 filed · Value $3.58M — Silva Paul M, Sachdev Amit, Chodakewitz Jeffrey2017-04-03: 1 option exercise at $107.45 close — Chodakewitz Jeffrey2017-04-28: 6 option exercises at $118.30 close — ALTSHULER DAVID, Arbuckle Stuart A, LEIDEN JEFFREY M2017-05-02: 1 option exercise at $118.47 close — Chodakewitz Jeffrey2017-06-01: 2 award or grants at $127.16 close — SACHS BRUCE I, BOGER JOSHUA S2017-06-01: 15 option exercises at $127.16 close — Silva Paul M, Sachdev Amit, Chodakewitz Jeffrey and 8 more2017-06-02: 4 option exercises at $129.90 close — Arbuckle Stuart A, LEIDEN JEFFREY M2017-06-05: 1 option exercise at $130.17 close — ALTSHULER DAVID2017-06-08: 1 option exercise at $125.91 close — Garber Alan M2017-06-21: 2 option exercises at $134.83 close — Silva Paul M, Chodakewitz Jeffrey2017-07-03: 1 option exercise at $128.23 close — Chodakewitz Jeffrey2017-07-17: 1 option exercise at $129.21 close — Chodakewitz Jeffrey2017-07-19: 25 option exercises at $159.69 close — Silva Paul M, SMITH IAN F, Sachdev Amit and 5 more2017-07-21: 1 option exercise at $163.17 close — Arbuckle Stuart A2017-07-31: 4 option exercises at $151.82 close — LEIDEN JEFFREY M, SMITH IAN F, Silva Paul M and 1 more2017-08-02: 3 option exercises at $157.55 close — SMITH IAN F, Chodakewitz Jeffrey, Silva Paul M2017-08-03: 3 option exercises at $154.03 close — Arbuckle Stuart A, Parini Michael, Chodakewitz Jeffrey2017-08-07: 3 option exercises at $156.47 close — Silva Paul M, Arbuckle Stuart A, SMITH IAN F2017-08-31: 1 option exercise at $160.54 close — ALTSHULER DAVID2017-10-02: 1 option exercise at $152.23 close — Chodakewitz Jeffrey2017-10-12: 1 option exercise at $153.98 close — Parini Michael2017-10-16: 2 option exercises at $154.70 close — SMITH IAN F, Chodakewitz Jeffrey2017-10-27: 1 option exercise at $150.11 close — Arbuckle Stuart A2017-11-02: 1 option exercise at $144.90 close — Chodakewitz Jeffrey2017-11-03: 4 option exercises at $149.97 close — SMITH IAN F, Parini Michael, Bhatia Sangeeta N. and 1 more2017-11-06: 2 option exercises at $148.98 close — SMITH IAN F, Arbuckle Stuart A2017-12-27: 1 option exercise at $151.55 close — Silva Paul M2018-01-02: 1 option exercise at $152.91 close — Chodakewitz Jeffrey2018-01-05: 1 option exercise at $155.69 close — Bhatia Sangeeta N.2018-01-11: 1 option exercise at $158.40 close — Arbuckle Stuart A2018-01-12: 1 option exercise at $157.93 close — Parini Michael2018-01-16: 5 option exercises at $155.71 close — LEIDEN JEFFREY M, SMITH IAN F, Chodakewitz Jeffrey and 1 more2018-01-19: 2 option exercises at $157.97 close — Sachdev Amit2018-01-22: 4 option exercises at $161.91 close — MCGLYNN MARGARET G, Silva Paul M, ALTSHULER DAVID and 1 more2018-01-23: 4 option exercises at $166.58 close — Sachdev Amit, MCGLYNN MARGARET G, Silva Paul M2018-01-24: 2 option exercises at $167.45 close — Arbuckle Stuart A2018-01-29: 1 option exercise at $167.14 close — Sachdev Amit2018-02-01: 1 option exercise at $172.99 close — Silva Paul M2018-02-02: 4 option exercises at $166.24 close — ALTSHULER DAVID, Chodakewitz Jeffrey, Silva Paul M and 1 more2018-02-05: 8 option exercises at $155.14 close — Sachdev Amit, Chodakewitz Jeffrey, Parini Michael and 2 more2018-02-06: 9 award or grants at $159.27 close — Silva Paul M, SMITH IAN F, Graney Thomas and 6 more2018-02-26: 2 option exercises at $169.54 close — Sachdev Amit, Arbuckle Stuart A2018-03-02: 1 option exercise at $170.06 close — MCGLYNN MARGARET G2018-03-09: 1 option exercise at $176.26 close — Sachdev Amit2018-04-16: 1 option exercise at $158.70 close — Arbuckle Stuart A2018-04-18: 1 option exercise at $163.36 close — Silva Paul M2018-04-25: 4 option exercises at $155.15 close — Parini Michael, SMITH IAN F2018-04-26: 2 option exercises at $158.81 close — SMITH IAN F2018-05-03: 1 option exercise at $149.64 close — Parini Michael2018-05-11: 2 option exercises at $155.97 close — SMITH IAN F2018-06-01: 8 award or grants at $152.05 close — MCGLYNN MARGARET G, Bhatia Sangeeta N., SACHS BRUCE I and 5 more2018-06-22: 3 option exercises at $159.19 close — Arbuckle Stuart A, SMITH IAN F, LEIDEN JEFFREY M2018-06-29: 10 option exercises at $169.96 close — ALTSHULER DAVID, SMITH IAN F, Arbuckle Stuart A and 2 more2018-07-05: 1 option exercise at $169.49 close — Parini Michael2018-07-12: 2 option exercises at $178.27 close — Parini Michael, Silva Paul M2018-07-13: 2 option exercises at $180.50 close — Sachdev Amit, Arbuckle Stuart A2018-07-16: 4 option exercises at $181.22 close — Silva Paul M, ALTSHULER DAVID, Sachdev Amit and 1 more2018-08-02: 5 option exercises at $177.89 close — Sachdev Amit, ALTSHULER DAVID, Silva Paul M and 1 more2018-08-03: 6 option exercises at $174.54 close — Parini Michael, Sachdev Amit, ALTSHULER DAVID and 2 more2018-08-28: 1 option exercise at $180.87 close — ALTSHULER DAVID2018-10-01: 1 option exercise at $191.57 close — ALTSHULER DAVID2018-10-03: 2 option exercises at $192.21 close — Bhatia Sangeeta N.2018-10-04: 1 option exercise at $188.62 close — Parini Michael2018-10-12: 1 option exercise at $181.32 close — Parini Michael2018-11-02: 3 option exercises at $173.29 close — Sachdev Amit, ALTSHULER DAVID, Arbuckle Stuart A2018-11-05: 5 option exercises at $174.59 close — Sachdev Amit, Parini Michael, Arbuckle Stuart A and 1 more2018-11-07: 2 option exercises at $183.88 close — Arbuckle Stuart A, ALTSHULER DAVID2018-12-03: 1 option exercise at $184.65 close — Silva Paul M2018-12-06: 1 option exercise at $179.61 close — SACHS BRUCE I2019-01-04: 1 option exercise at $172.70 close — Parini Michael2019-01-14: 1 option exercise at $183.91 close — Parini Michael2019-01-17: 3 option exercises at $190.52 close — Silva Paul M2019-01-18: 1 option exercise at $194.70 close — ALTSHULER DAVID2019-01-22: 3 option exercises at $193.88 close — Parini Michael, Arbuckle Stuart A, ALTSHULER DAVID2019-02-04: 9 option exercises at $88.79 filed · Value $364.23K — Sachdev Amit, Arbuckle Stuart A, Silva Paul M and 2 more2019-02-06: 7 award or grants at $182.39 close — Sachdev Amit, Silva Paul M, LEIDEN JEFFREY M and 4 more2019-02-06: 1 option exercise at $182.39 close — Silva Paul M2019-04-10: 1 award or grant at $190.37 close — WAGNER CHARLES F JR2019-04-16: 2 option exercises at $179.74 close — Parini Michael2019-05-01: 2 option exercises at $172.60 close — LEIDEN JEFFREY M2019-05-02: 1 option exercise at $169.54 close — Arbuckle Stuart A2019-05-03: 2 option exercises at $173.87 close — Parini Michael, Arbuckle Stuart A2019-05-06: 2 option exercises at $174.76 close — LEIDEN JEFFREY M2019-05-24: 1 option exercise at $171.77 close — LEIDEN JEFFREY M2019-06-01: 5 award or grants at $166.18 close — ULLIAN ELAINE, SACHS BRUCE I, MCGLYNN MARGARET G and 2 more2019-06-18: 1 option exercise at $177.94 close — LEIDEN JEFFREY M2019-06-19: 1 option exercise at $181.75 close — Arbuckle Stuart A2019-07-05: 1 option exercise at $178.34 close — Parini Michael2019-07-12: 1 option exercise at $175.79 close — Parini Michael2019-08-02: 1 option exercise at $178.39 close — Arbuckle Stuart A2019-08-05: 2 option exercises at $175.56 close — Parini Michael, Arbuckle Stuart A2019-08-08: 1 option exercise at $182.94 close — Arbuckle Stuart A2019-08-13: 1 option exercise at $183.91 close — MCGLYNN MARGARET G2019-08-19: 2 option exercises at $187.09 close — ALTSHULER DAVID2019-10-02: 2 option exercises at $166.71 close — Bhatia Sangeeta N.2019-10-14: 1 option exercise at $173.59 close — Parini Michael2019-10-17: 1 option exercise at $177.72 close — Parini Michael2019-10-22: 5 option exercises at $191.06 close — Sachdev Amit, MCGLYNN MARGARET G, LEIDEN JEFFREY M and 1 more2019-10-25: 1 option exercise at $194.49 close — Sachdev Amit2019-10-30: 1 option exercise at $199.28 close — Kewalramani Reshma2019-10-31: 1 option exercise at $195.48 close — LEIDEN JEFFREY M2019-11-01: 7 option exercises at $200.94 close — Kearney Terrence C, LEIDEN JEFFREY M, Bhatia Sangeeta N.2019-11-04: 7 option exercises at $199.42 close — Sachdev Amit, Parini Michael, Arbuckle Stuart A and 1 more2019-11-06: 1 option exercise at $195.97 close — ALTSHULER DAVID2019-11-08: 1 option exercise at $201.31 close — Kewalramani Reshma2019-11-13: 3 option exercises at $207.10 close — Tatsis Ourania, Parini Michael, Arbuckle Stuart A2019-11-15: 2 option exercises at $209.80 close — LEIDEN JEFFREY M2019-11-18: 2 option exercises at $210.00 close — LEIDEN JEFFREY M2019-11-19: 3 option exercises at $215.00 close — LEIDEN JEFFREY M, Sachdev Amit2019-11-25: 2 option exercises at $223.27 close — Sachdev Amit, Kewalramani Reshma2019-11-26: 1 option exercise at $219.05 close — ALTSHULER DAVID2019-12-09: 1 option exercise at $219.37 close — Sachdev Amit2019-12-30: 1 option exercise at $218.97 close — YOUNG WILLIAM D2020-01-02: 5 option exercises at $219.45 close — YOUNG WILLIAM D, Silva Paul M2020-01-06: 1 option exercise at $224.03 close — Parini Michael2020-01-08: 3 option exercises at $231.09 close — Sachdev Amit, Silva Paul M, Tatsis Ourania2020-01-13: 2 option exercises at $226.49 close — Silva Paul M, Parini Michael2020-01-16: 1 option exercise at $235.50 close — Sachdev Amit2020-01-22: 1 option exercise at $234.61 close — Parini Michael2020-01-31: 4 option exercises at $227.05 close — Silva Paul M, SACHS BRUCE I, Parini Michael and 1 more2020-02-03: 9 option exercises at $230.51 close — Silva Paul M, Sachdev Amit, ALTSHULER DAVID and 2 more2020-02-04: 1 option exercise at $239.66 close — Lee Yuchun2020-02-05: 1 option exercise at $240.76 close — Lee Yuchun2020-02-06: 12 option exercises at $239.12 close — Lee Yuchun, Tatsis Ourania, Silva Paul M and 4 more2020-02-07: 1 option exercise at $240.06 close — Lee Yuchun2020-02-10: 1 option exercise at $244.75 close — Lee Yuchun2020-04-06: 1 option exercise at $255.30 close — Silva Paul M2020-04-13: 1 option exercise at $252.28 close — Silva Paul M2020-04-20: 1 option exercise at $273.26 close — Lee Yuchun2020-04-21: 1 option exercise at $262.80 close — Lee Yuchun2020-04-22: 1 option exercise at $269.37 close — Lee Yuchun2020-04-23: 1 option exercise at $267.91 close — Lee Yuchun2020-04-24: 1 option exercise at $269.86 close — Lee Yuchun2020-04-27: 1 option exercise at $268.51 close — Lee Yuchun2020-04-28: 1 option exercise at $256.96 close — Lee Yuchun2020-04-29: 1 option exercise at $251.05 close — Parini Michael2020-05-04: 7 option exercises at $264.69 close — Sachdev Amit, Arbuckle Stuart A, Silva Paul M and 2 more2020-05-05: 5 option exercises at $272.33 close — LEIDEN JEFFREY M, Sachdev Amit2020-05-06: 9 option exercises at $270.06 close — Tatsis Ourania, Silva Paul M, Sachdev Amit and 3 more2020-05-07: 6 option exercises at $270.01 close — SACHS BRUCE I, LEIDEN JEFFREY M2020-05-11: 2 option exercises at $285.28 close — Sachdev Amit, Parini Michael2020-05-12: 5 option exercises at $276.47 close — LEIDEN JEFFREY M, ALTSHULER DAVID2020-06-01: 6 award or grants at $286.64 close — YOUNG WILLIAM D, SACHS BRUCE I, MCGLYNN MARGARET G and 3 more2020-07-07: 2 option exercises at $299.06 close — Arbuckle Stuart A2020-07-13: 2 option exercises at $284.82 close — Silva Paul M, Parini Michael2020-08-03: 5 option exercises at $279.52 close — Sachdev Amit, Silva Paul M, Parini Michael and 2 more2020-08-06: 6 option exercises at $273.34 close — Silva Paul M, Parini Michael, Kewalramani Reshma and 1 more2020-10-05: 1 option exercise at $268.98 close — Bhatia Sangeeta N.2020-11-03: 1 option exercise at $211.14 close — Arbuckle Stuart A2020-11-04: 1 option exercise at $215.09 close — Parini Michael2021-02-03: 2 option exercises at $211.00 close — Parini Michael, Arbuckle Stuart A2021-04-27: 1 option exercise at $215.53 close — Sachdev Amit2021-05-01: 5 award or grants at $218.20 close — SACHS BRUCE I, MCGLYNN MARGARET G, Lee Yuchun and 2 more2022-01-28: 1 option exercise at $127.54 filed · Value $637.70K — MCGLYNN MARGARET G2022-02-02: 1 option exercise at $86.52 filed · Value $403.18K — ALTSHULER DAVID2022-04-04: 1 option exercise at $81.54 filed · Value $163.08K — Lee Yuchun2022-04-05: 1 option exercise at $81.54 filed · Value $163.08K — Lee Yuchun2022-04-06: 1 option exercise at $272.39 close — Lee Yuchun2022-04-07: 1 option exercise at $275.83 close — Lee Yuchun2022-04-08: 3 option exercises at $280.28 close — Lee Yuchun, Bhatia Sangeeta N., MCGLYNN MARGARET G2022-04-11: 1 option exercise at $281.09 close — Lee Yuchun2022-04-12: 1 option exercise at $281.15 close — Lee Yuchun2022-04-13: 1 option exercise at $290.93 close — Lee Yuchun2022-04-14: 1 option exercise at $287.97 close — Lee Yuchun2022-04-18: 1 option exercise at $282.99 close — Lee Yuchun2022-05-01: 5 award or grants at $273.22 close — Kearney Terrence C, Lee Yuchun, MCGLYNN MARGARET G and 2 more2022-07-19: 2 option exercises at $289.60 close — ALTSHULER DAVID2022-07-25: 1 option exercise at $283.68 close — LEIDEN JEFFREY M2022-08-08: 1 option exercise at $293.95 close — ALTSHULER DAVID2022-08-09: 1 option exercise at $298.83 close — Arbuckle Stuart A2022-08-10: 1 option exercise at $295.77 close — Arbuckle Stuart A2022-08-15: 1 option exercise at $305.53 close — Arbuckle Stuart A2022-11-07: 1 option exercise at $303.23 close — ALTSHULER DAVID2023-01-17: 1 option exercise at $311.98 close — Lee Yuchun2023-01-18: 1 option exercise at $309.86 close — Lee Yuchun2023-01-23: 1 option exercise at $311.81 close — Lee Yuchun2023-01-24: 1 option exercise at $313.57 close — Lee Yuchun2023-01-25: 1 option exercise at $315.28 close — Lee Yuchun2023-01-26: 1 option exercise at $321.02 close — Lee Yuchun2023-01-27: 1 option exercise at $321.45 close — Lee Yuchun2023-01-31: 1 option exercise at $323.10 close — SACHS BRUCE I2023-02-06: 1 option exercise at $304.87 close — ALTSHULER DAVID2023-04-12: 1 option exercise at $326.37 close — SACHS BRUCE I2023-05-01: 5 award or grants at $345.00 close — SACHS BRUCE I, MCGLYNN MARGARET G, Lee Yuchun and 2 more2023-06-15: 1 option exercise at $349.08 close — Arbuckle Stuart A2023-07-17: 1 option exercise at $357.98 close — SACHS BRUCE I2023-08-10: 1 option exercise at $347.38 close — Kearney Terrence C2023-11-06: 1 option exercise at $385.76 close — SACHS BRUCE I2023-12-13: 1 option exercise at $405.07 close — Arbuckle Stuart A2023-12-15: 2 option exercises at $410.68 close — Kewalramani Reshma2024-05-01: 5 award or grants at $402.14 close — Thornberry Nancy, SACHS BRUCE I, Lagarde Michel and 2 more2024-05-22: 1 option exercise at $447.53 close — SACHS BRUCE I2024-05-24: 1 option exercise at $456.95 close — Kewalramani Reshma2024-08-01: 1 option exercise at $505.78 close — SACHS BRUCE I2024-08-08: 1 option exercise at $465.96 close — Bhatia Sangeeta N.2024-08-30: 1 option exercise at $495.89 close — Bhatia Sangeeta N.2025-05-01: 4 award or grants at $498.86 close — Thornberry Nancy, SACHS BRUCE I, Lagarde Michel and 1 more2025-11-13: 1 option exercise at $434.52 close — LEIDEN JEFFREY M2025-11-14: 2 option exercises at $437.15 close — LEIDEN JEFFREY M2025-12-03: 1 option exercise at $463.13 close — LEIDEN JEFFREY M2025-12-04: 1 option exercise at $457.36 close — LEIDEN JEFFREY M2026-01-06: 1 option exercise at $468.38 close — WAGNER CHARLES F JR2026-02-19: 2 option exercises at $469.27 close — Sachdev Amit2026-05-01: 7 award or grants at $423.92 close — Upadhyay Suketu, Thornberry Nancy, Schneider Jennifer and 4 more

Logarithmic scale. Both lines share the same starting value for the selected range.

Markers: each transaction type positioned at that session's split-adjusted close. Tooltips retain the reported transaction price when available.

Transaction dateReporting ownerFormSecurityTransactionSharesPricePrice that dayFiling
2026-05-01Upadhyay Suketu
Director		4Stock Option (Right to Buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+2,866
2,866 owned after		$424.45
exercise price		$423.922026-05-05
2026-05-01Thornberry Nancy
Director		4Stock Option (Right to Buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,433
1,433 owned after		$424.45
exercise price		$423.922026-05-05
2026-05-01Schneider Jennifer
Director		4Stock Option (Right to Buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,433
1,433 owned after		$424.45
exercise price		$423.922026-05-05
2026-05-01SACHS BRUCE I
Director		4Stock Option (Right to Buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+2,866
2,866 owned after		$424.45
exercise price		$423.922026-05-05
2026-05-01Lagarde Michel
Director		4Stock Option (Right to Buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+2,866
2,866 owned after		$424.45
exercise price		$423.922026-05-05
2026-05-01Garber Alan M
Director		4Stock Option (Right to Buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,433
1,433 owned after		$424.45
exercise price		$423.922026-05-05
2026-05-01CARNEY LLOYD
Director		4Stock Option (Right to Buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+2,866
2,866 owned after		$424.45
exercise price		$423.922026-05-05
2026-03-03
holding as of filing		Liu Joy
Officer (EVP and Chief Legal Officer)		3Stock Option (Right to Buy)
Derivative · Direct		Holding$155.57
exercise price		2026-03-03
2026-03-03
holding as of filing		Liu Joy
Officer (EVP and Chief Legal Officer)		3Stock Option (Right to Buy)
Derivative · Direct		Holding$187.53
exercise price		2026-03-03
2026-02-19Sachdev Amit
Officer (EVP Chief Patient & Ext Af Off)		4Stock Option (Right to Buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−23,479
0 owned after		$155.57
exercise price		$469.272026-02-23
2026-02-19Sachdev Amit
Officer (EVP Chief Patient & Ext Af Off)		4Stock Option (Right to Buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−25,026
0 owned after		$187.53
exercise price		$469.272026-02-23
2026-01-06WAGNER CHARLES F JR
Officer (EVP, CO & FO)		4Stock Option (Right to Buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−9,532
0 owned after		$189.38
exercise price		$468.382026-01-08

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