| 2026-06-11 | 8-K | 10.3 | Amended and Restated Palisade Bio, Inc. 2021 Employee Stock Purchase Plan |
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| 2026-06-11 | 8-K | 10.2 | Amended and Restated Palisade Bio, Inc. 2021 Equity Incentive Plan |
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| 2026-05-12 | 10-Q | 10.1 | Palisade Bio, Inc. Equity Award Policy. |
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| 2025-11-10 | 10-Q | 10.5 | Form of Restricted Stock Unit Grant Notice and Award Agreement under the Palisade Bio, Inc. 2021 Equity Incentive Plan (Optional Cash Settlement). |
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| 2025-11-10 | 10-Q | 10.4 | Form of Restricted Stock Unit Grant Notice and Award Agreement under the Palisade Bio, Inc. 2021 Equity Incentive Plan. |
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| 2025-11-10 | 10-Q | 10.2 | Amended and Restated Employment Agreement with Mitchell Jones, dated September 4, 2025. |
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| 2025-11-10 | 10-Q | 10.1 | Amended and Restated Employment Agreement with J.D. Finley, dated September 4, 2025. |
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| 2025-07-25 | 8-K | 10.1 | Form of Warrant Inducement Agreement |
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| 2024-12-16 | 8-K | 10.1 | Form of Warrant Amendment Agreement |
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| 2024-09-27 | 8-K | 10.1 | Form of Employment Agreement with J.D. Finley, dated September 25, 2024 |
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| 2024-08-12 | 10-Q | 10.48 | Amendment to Research Collaboration and License Agreement with Giiant Pharma, Inc. dated August 2, 2024. |
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| 2024-05-03 | 8-K | 10.3 | Form of Placement Agency Agreement |
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| 2024-05-03 | 8-K | 10.2 | Form of Registration Rights Agreement |
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| 2024-05-03 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2024-02-01 | 8-K | 10.1 | Form of Warrant Inducement Agreement |
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| 2023-09-11 | 8-K | 10.1 | Form of Employment Agreement with Mitchell Jones, dated September 5, 2023 |
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| 2023-09-11 | 8-K | 10.2 | Form of Placement Agency Agreement |
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| 2023-09-11 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2023-09-08 | 8-K | 10.1 | Form of Research Collaboration and License Agreement with Giiant Pharma |
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| 2023-08-10 | 10-Q | 10.20 | Palisade Bio, Inc. 2021 Inducement Incentive Plan, as Amended August 7, 2023. |
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| 2023-06-09 | 8-K | 10.2 | Palisade 2021 Employee Stock Purchase Plan, as amended |
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| 2023-06-09 | 8-K | 10.1 | Palisade 2021 Equity Incentive Plan, as amended |
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| 2023-04-05 | 8-K | 10.3 | Form of Placement Agency Agreement |
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| 2023-04-05 | 8-K | 10.2 | Form of Registration Rights Agreement |
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| 2023-04-05 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2023-03-22 | 10-K | 10.36 | Form of Consulting Agreement dated April 7, 2023 by and between Dr. Herbert Slade and the Company. |
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| 2023-03-22 | 10-K | 10.35 | Form of First Amendment Consulting Agreement dated January 25, 2023 by and between Dr. Herbert Slade and the Company. |
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| 2023-03-22 | 10-K | 10.23 | Non-Employee Director Compensation Policy |
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| 2023-01-04 | 8-K | 10.3 | Form of Placement Agent Agreement |
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| 2023-01-04 | 8-K | 10.2 | Form of Registration Rights Agreement |
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| 2023-01-04 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2022-10-14 | 8-K | 10.1 | Separation Agreement and Release with former Chief Executive Officer |
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| 2022-08-15 | 10-Q | 10.2 | First Amendment dated July 14, 2022 to the Office Lease Between AP Beacon Carlsbad, LP, and Palisade Bio, Inc., dated May 12, 2022. |
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| 2022-05-13 | 10-Q | 10.1 | Office Lease Between AP Beacon Carlsbad, LP, and Palisade Bio, Inc., dated May 12, 2022 |
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| 2022-05-06 | 8-K | 10.1 | Placement Agency Agreement, dated May 6, 2022, by and between the Company and Ladenburg Thalmann & Co. Inc. |
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| 2022-05-06 | 8-K | 10.1 | Form of Securities Purchase Agreement, dated May 6, 2022, by and among the Company and the purchasers named therein |
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| 2022-03-17 | 10-K | 10.27 | Asset Transfer Agreement, by and between Alto Neuroscience, Inc. and Palisade Bio, Inc., dated October 18, 2021. |
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| 2022-03-17 | 10-K | 10.23 | Non-Employee Director Compensation Policy. |
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| 2022-03-17 | 10-K | 10.5 | License Agreement, by and between Palisade Bio, Inc. and The Regents of the University of California, dated July 6, 2021. |
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| 2021-11-23 | 8-K | 10.6 | Palisade Bio, Inc. 2021 Equity Incentive Plan, as amended. |
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| 2021-11-23 | 8-K | 10.5 | Form of Non-Employee Director Stock Option Grant Notice, Stock Option Agreement and Notice of Exercise under the Palisade Bio, Inc. 2021 Equity Incentive Plan. |
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| 2021-11-23 | 8-K | 10.4 | Form of Stock Option Grant Notice, Stock Option Agreement and Notice of Exercise under the Palisade Bio, Inc. 2021 Equity Incentive Plan. |
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| 2021-11-23 | 8-K | 10.1 | Palisade Bio, Inc. 2021 Inducement Incentive Plan. |
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| 2021-05-14 | 10-Q | 10.3 | Amendment Agreement to Securities Purchase Agreement by and among, the Company, Leading BioSciences, Inc. and Altium Growth Fund, LP, dated May 3, 2021 |
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| 2021-04-27 | 8-K | 10.1 | Contingent Value Rights Agreement, dated as of April 27, 2021, by and among the Company, American Stock Transfer & Trust Company, LLC and Raul Silvestre. |
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| 2021-03-18 | 8-K | 10.1 | Form of Separation Agreement |
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| 2020-12-21 | 8-K | 10.7 | Form of Leak-Out Agreement, by and between Seneca Biopharma, Inc. and the investor party thereto. |
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| 2020-12-21 | 8-K | 10.6 | Securities Purchase Agreement, by and among Seneca Biopharma, Inc., Leading BioSciences, Inc. and the investor party thereto, dated December 16, 2020. |
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| 2020-12-21 | 8-K | 10.5 | Securities Purchase Agreement, by and between Leading BioSciences, Inc. and the investor party thereto, dated December 16, 2020. |
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| 2020-12-21 | 8-K | 10.4 | Form of LBS Lock-Up Agreement. |
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| 2020-12-21 | 8-K | 10.3 | Form of Company Lock-Up Agreement. |
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| 2020-12-21 | 8-K | 10.2 | Form of LBS Support Agreement, dated as of December 16, 2020, by and between Seneca Biopharma, Inc. and each of the parties named in each agreement therein. |
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| 2020-12-21 | 8-K | 10.1 | Form of Company Support Agreement, dated as of December 16, 2020, by and between Leading BioSciences, Inc. and each of the parties named in each agreement therein. |
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| 2020-05-27 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2020-04-02 | 8-K | 10.2 | Employment Agreement with Matthew Kalnik, PhD |
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| 2020-04-02 | 8-K | 10.1 | Employment Agreement with Dane Saglio |
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| 2020-03-27 | 10-K | 10.25 | Amendment to Employment Agreement with Kenneth Carter effective April 1,2020 |
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| 2020-01-22 | 8-K | 10.2 | Form of Placement Agent Agreement |
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| 2020-01-22 | 8-K | 10.1 | Letter Agreement dated January 17, 2020 |
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| 2018-12-18 | 8-K | 10.3 | Indemnification Agreement |
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| 2018-12-18 | 8-K | 10.2 | Confidential Information and Invention Assignment Agreement |
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| 2018-12-18 | 8-K | 10.1 | Kenneth Carter Employment Agreement |
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| 2018-10-29 | 8-K | 10.2 | Form of Placement Agent Agreement |
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| 2018-10-29 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2018-08-09 | 8-K | 10.1 | Jim Scully Binding Term Sheet |
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| 2017-05-04 | 8-K | 10.1 | Separation Agreement and Release with former CFO |
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| 2017-03-20 | 8-K | 10.1 | Letter Agreement for Warrant Exercises |
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| 2016-11-08 | 10-Q | 10.23 | Form of Securities Purchase Agreement between Issuer and Richard Daly |
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| 2016-11-08 | 10-Q | 10.22 | Form of Securities Purchase Agreement between Issuer and Jonathan Lloyd Jones |
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| 2016-09-12 | 8-K | 10.1 | Securities Purchase Agreement. |
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| 2016-06-16 | 8-K | 10.1 | Form of Amendment to General Release and Waiver of Claims Agreement between Neuralstem and I. Richard Garr |
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| 2016-05-13 | 8-K | 10.1 | Form of Securities Purchase Agreement. |
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| 2016-03-04 | 8-K | 10.1 | General Release and Waiver of Claims |
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| 2016-02-19 | 8-K | 10.2 | Confidential Information and Invention Assignment Agreement |
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| 2016-02-19 | 8-K | 10.1 | Richard Daly Employment Agreement |
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| 2015-11-16 | 8-K | 10.1 | Form of Indemnification Agreement |
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| 2015-05-11 | 8-K | 10.1 | Offer Letter between Neuralstem, Inc. and Jonathan Lloyd Jones |
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| 2015-03-02 | 8-K | 10.1 | EMPLOYMENT AGREEMENT AMENDMENT |
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| 2014-10-29 | 8-K | 10.1 | Form of Second Amendment dated October 28, 2014 |
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| 2014-09-18 | 8-K | 10.1 | Form of Employment Agreement Amendment of Dr. Karl Johe |
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| 2014-03-10 | 10-K | 10.13 | Form of Outside Director Agreement |
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| 2014-01-06 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2013-10-25 | 8-K | 10.1 | At The Market Offering Agreement |
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| 2013-09-10 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2013-03-27 | 8-K | 10.2 | Form of Intellectual Property and Security Agreement |
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| 2013-03-27 | 8-K | 10.1 | Form of Loan and Security Agreement dated |
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| 2012-07-27 | 8-K | 10.3 | Form of Renewal Agreement of Dr. Tom Hazel |
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| 2012-07-27 | 8-K | 10.2 | Form of Renewal Agreement of Dr. Karl Johe |
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| 2012-07-27 | 8-K | 10.1 | Form of Renewal Agreement of I. Richard Garr |
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| 2012-02-08 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2011-03-16 | 10-K | 10.7 | Consulting Agreement dated January 2010 between Market Development Consulting Group and the Company and amendments No. 1 and 2. |
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| 2010-10-05 | 10-K/A | 10.5 | Employment Agreement with Thomas Hazel, Ph.D. dated August 11, 2008 |
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| 2010-07-14 | 8-K | 10.1 | 2010 Equity Compensation Plan |
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| 2010-06-29 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2009-07-01 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2009-03-31 | 10-K | 10.4 | Amended terms to the Employment Agreement of Karl Johe dated January 1, 2009 |
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| 2009-03-31 | 10-K | 10.2 | Amended terms to the Employment Agreement of I Richard Garr dated January 1, 2008 |
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