Return on equity (ROE) is the profit a company earns for every dollar of shareholder money invested in it, shown as a percentage. It is net income divided by shareholder equity, and the table shows both amounts: the profit earned and the equity it was earned on. A higher ROE means more profit per dollar of equity, but ROE also rises when equity shrinks through buybacks, dividends or losses, and it has no meaning for a company with negative equity. Quarterly points divide the trailing four quarters of net income by the balance at that quarter end; annual points divide the filed fiscal-year net income by the fiscal-year-end balance.
IONIS PHARMACEUTICALS INC roe for the quarter ending 2026-06-30 was -128.53%, a change of -86.07% year-over-year.
IONIS PHARMACEUTICALS INC roe for the quarter ending 2026-03-31 was -66.54%, a change of 29.74% year-over-year.
IONIS PHARMACEUTICALS INC roe for the quarter ending 2025-12-31 was -77.98%, a change of -0.83% year-over-year.
IONIS PHARMACEUTICALS INC roe for the quarter ending 2025-09-30 was -41.48%, a change of 12.68% year-over-year.
IONIS PHARMACEUTICALS INC roe for fiscal 2025 was -77.98%, a change of -0.83% from fiscal 2024.
IONIS PHARMACEUTICALS INC roe for fiscal 2024 was -77.15%, a change of 17.58% from fiscal 2023.
IONIS PHARMACEUTICALS INC roe for fiscal 2023 was -94.72%, a change of -47.64% from fiscal 2022.
IONIS PHARMACEUTICALS INC roe for fiscal 2022 was -47.08%, a change of -43.38% from fiscal 2021.