Pre-tax margin is the percentage of revenue left as profit after every expense except income tax. It is income before income tax divided by revenue, and the table shows both amounts beside the percentage. It sits between operating margin and net margin: it includes interest and other non-operating items but not the tax charge, so the gap down to net margin is the tax burden. Quarterly and annual points each use the amounts filed for that same period, so a single quarter can swing with the seasons.
IONIS PHARMACEUTICALS INC pre-tax margin for the quarter ending 2017-09-30 was -3.25%, a 149.11% decline year-over-year.
IONIS PHARMACEUTICALS INC pre-tax margin for the quarter ending 2017-06-30 was -10.55%, a change of 137.84% year-over-year.
IONIS PHARMACEUTICALS INC pre-tax margin for the quarter ending 2017-03-31 was 3.14%, a change of 173.14% year-over-year.
IONIS PHARMACEUTICALS INC pre-tax margin for the quarter ending 2016-12-31 was 17.96%, a change of 155.75% year-over-year.
IONIS PHARMACEUTICALS INC pre-tax margin for fiscal 2025 was -40.22%, a change of 25.02% from fiscal 2024.
IONIS PHARMACEUTICALS INC pre-tax margin for fiscal 2024 was -65.25%, a change of -22.84% from fiscal 2023.
IONIS PHARMACEUTICALS INC pre-tax margin for fiscal 2023 was -42.40%, a change of 1.52% from fiscal 2022.
IONIS PHARMACEUTICALS INC pre-tax margin for fiscal 2022 was -43.92%, a change of -40.33% from fiscal 2021.