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Ionis Pharmaceuticals, Inc. (IONS) Scorecard

2.8 / 5 stars · 68/120 Roast Me

Ionis Pharmaceuticals, Inc. (IONS) Scorecard

  • 2026-Q2: Total return Lose; Revenue growth Lose; EPS growth Win.
  • 2026-Q1: Total return Lose; Revenue growth Win; EPS growth Lose.
  • 2025-Q4: Total return Win; Revenue growth Win; EPS growth Lose.
  • 2025-Q3: Total return Win; Revenue growth Win; EPS growth Lose.
52/120 All 120 Win/Lose results shown below

Every strict quarterly win earns 1 point. A loss, tie, or unavailable scoring value earns 0.

Trailing 1 year (4 quarters): 6 wins, 6 lossesLast fetched: 4 Sept 2026

Complete point ledger

Each cell identifies the missing side explicitly.

QuarterTotal returnRevenue growthEPS growth
2026-Q21/3 LoseIONS / S&P
5.59% / 15.20%
LoseIONS / S&P
-7.41% / 15.00%
WinIONS / S&P
89.13% / 50.40%
2026-Q11/3 LoseIONS / S&P
-5.08% / -4.33%
WinIONS / S&P
47.53% / 11.30%
LoseIONS / S&P
-30.10% / 27.70%
2025-Q42/3 WinIONS / S&P
20.93% / 2.65%
WinIONS / S&P
33.83% / 9.00%
LoseIONS / S&P
-19.08% / 13.40%
2025-Q32/3 WinIONS / S&P
65.58% / 8.12%
WinIONS / S&P
20.41% / 4.61%
LoseIONS / S&P
-30.74% / 13.45%
2025-Q22/3 WinIONS / S&P
30.96% / 10.94%
WinIONS / S&P
16.05% / 4.83%
LoseIONS / S&P
-26.98% / 10.63%
2025-Q11/3 LoseIONS / S&P
-13.70% / -4.27%
LoseIONS / S&P
-7.64% / 4.98%
WinIONS / S&P
11.99% / 10.57%
2024-Q41/3 LoseIONS / S&P
-12.73% / 2.41%
LoseIONS / S&P
-10.48% / 5.25%
WinIONS / S&P
18.75% / 6.15%
2024-Q31/3 LoseIONS / S&P
-15.95% / 5.89%
WinIONS / S&P
30.57% / 5.89%
LoseIONS / S&P
-14.98% / 6.11%
2024-Q23/3 WinIONS / S&P
9.94% / 4.28%
WinIONS / S&P
29.00% / 5.38%
WinIONS / S&P
16.13% / 5.12%
2024-Q12/3 LoseIONS / S&P
-14.31% / 10.56%
WinIONS / S&P
34.84% / 5.71%
WinIONS / S&P
15.58% / 5.59%
2023-Q42/3 LoseIONS / S&P
11.53% / 11.69%
WinIONS / S&P
34.10% / 6.81%
WinIONS / S&P
34.74% / 7.78%
2023-Q31/3 WinIONS / S&P
10.55% / -3.27%
LoseIONS / S&P
-29.75% / 7.52%
LoseIONS / S&P
-4200.00% / -5.03%
2023-Q22/3 WinIONS / S&P
14.80% / 8.74%
LoseIONS / S&P
-25.71% / 9.50%
WinIONS / S&P
1105.56% / -8.57%
2023-Q11/3 LoseIONS / S&P
-5.37% / 7.50%
LoseIONS / S&P
-31.49% / 10.77%
WinIONS / S&P
23000.00% / -15.69%
2022-Q41/3 LoseIONS / S&P
-14.61% / 7.56%
LoseIONS / S&P
-27.53% / 11.88%
WinIONS / S&P
900.00% / -17.99%
2022-Q32/3 WinIONS / S&P
19.48% / -4.88%
WinIONS / S&P
32.50% / 13.47%
LoseIONS / S&P
-101.62% / -1.41%
2022-Q22/3 WinIONS / S&P
-0.05% / -16.10%
WinIONS / S&P
23.42% / 13.71%
LoseIONS / S&P
-95.42% / 11.04%
2022-Q12/3 WinIONS / S&P
21.72% / -4.60%
WinIONS / S&P
18.84% / 15.97%
LoseIONS / S&P
-99.72% / 42.23%
2021-Q40/3 LoseIONS / S&P
-9.27% / 11.03%
LoseIONS / S&P
11.13% / 15.00%
LoseIONS / S&P
-94.03% / 96.40%
2021-Q30/3 LoseIONS / S&P
-15.92% / 0.58%
LoseIONS / S&P
-29.16% / 10.77%
LoseIONS / S&P
-1021.28% / 69.42%
2021-Q20/3 LoseIONS / S&P
-11.28% / 8.55%
LoseIONS / S&P
-26.88% / 6.58%
LoseIONS / S&P
-573.49% / 51.81%
2021-Q10/3 LoseIONS / S&P
-20.48% / 6.17%
LoseIONS / S&P
-26.21% / -1.06%
LoseIONS / S&P
-454.00% / 7.39%
2020-Q41/3 WinIONS / S&P
19.16% / 12.15%
LoseIONS / S&P
-35.04% / -3.72%
LoseIONS / S&P
-267.37% / -33.42%
2020-Q31/3 LoseIONS / S&P
-19.52% / 8.93%
WinIONS / S&P
13.60% / -2.04%
LoseIONS / S&P
-85.27% / -27.10%
2020-Q22/3 WinIONS / S&P
24.70% / 20.54%
WinIONS / S&P
17.78% / -0.46%
LoseIONS / S&P
-72.15% / -27.11%
2020-Q11/3 LoseIONS / S&P
-21.73% / -19.60%
WinIONS / S&P
27.41% / 3.47%
LoseIONS / S&P
-62.96% / -14.75%
2019-Q41/3 LoseIONS / S&P
0.83% / 9.07%
WinIONS / S&P
87.20% / 5.36%
LoseIONS / S&P
-8.21% / 2.99%
2019-Q31/3 LoseIONS / S&P
-6.78% / 1.70%
WinIONS / S&P
42.70% / 5.02%
LoseIONS / S&P
-1129.03% / 0.21%
2019-Q21/3 LoseIONS / S&P
-20.82% / 4.30%
WinIONS / S&P
45.65% / 6.64%
LoseIONS / S&P
-1093.33% / 8.65%
2019-Q12/3 WinIONS / S&P
50.15% / 13.65%
WinIONS / S&P
38.63% / 8.12%
LoseIONS / S&P
-9100.00% / 14.29%
2018-Q43/3 WinIONS / S&P
4.81% / -13.52%
WinIONS / S&P
16.63% / 9.05%
WinIONS / S&P
4040.00% / 18.23%
2018-Q31/3 WinIONS / S&P
23.78% / 7.71%
LoseIONS / S&P
7.97% / 10.21%
LoseIONS / S&P
-167.39% / 19.06%
2018-Q20/3 LoseIONS / S&P
-5.47% / 3.43%
LoseIONS / S&P
4.33% / 9.03%
LoseIONS / S&P
-155.56% / 14.46%
2018-Q11/3 LoseIONS / S&P
-12.37% / -0.76%
WinIONS / S&P
20.17% / 7.68%
LoseIONS / S&P
-133.33% / 12.46%
2017-Q41/3 LoseIONS / S&P
-0.79% / 6.64%
WinIONS / S&P
37.93% / 7.03%
LoseIONS / S&P
-110.00% / 13.82%
2017-Q31/3 LoseIONS / S&P
-0.33% / 4.48%
WinIONS / S&P
124.05% / 5.68%
LoseIONS / S&P
-130.07% / 17.57%
2017-Q22/3 WinIONS / S&P
26.54% / 3.09%
WinIONS / S&P
198.52% / 4.83%
LoseIONS / S&P
-128.57% / 17.74%
2017-Q11/3 LoseIONS / S&P
-15.95% / 6.07%
WinIONS / S&P
75.08% / 3.67%
LoseIONS / S&P
-107.96% / 13.32%
2016-Q42/3 WinIONS / S&P
30.54% / 3.82%
WinIONS / S&P
31.40% / 2.09%
LoseIONS / S&P
IONS unavailable / 7.05%
2016-Q31/3 WinIONS / S&P
57.32% / 3.85%
LoseIONS / S&P
-24.97% / 0.20%
LoseIONS / S&P
IONS unavailable / -3.15%

Dividend-reinvested, split-adjusted total return

1Y · 2025-08-29 to 2026-08-27

MetricIONS total returnS&P 500 Total Return Index
Total return46.41%20.78%
Annualized return46.41%20.78%

5Y · 2021-09-01 to 2026-08-27

MetricIONS total returnS&P 500 Total Return Index
Total return54.99%83.14%
Annualized return9.16%12.86%

10Y · 2016-09-01 to 2026-08-27

MetricIONS total returnS&P 500 Total Return Index
Total return107.82%319.30%
Annualized return7.59%15.41%

Calculation rules

window
Latest 40 completed benchmark quarters; unavailable issuer evidence remains visible and scores 0.
return Basis
Issuer adjusted close reinvests distributions and normalizes splits; the S&P 500 Total Return Index is the direct benchmark.
point Rule
Strict same-quarter win = 1. Loss, tie or unavailable evidence = 0. No partial or subjective points.
frequency
Quarter endpoints only.
fundamentals
Trailing-four-quarter issuer revenue and EPS growth use the issuer's normalized government-filed facts.
non Scoring

Snapshot captured 2026-09-04.

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