Vapotherm, Inc. Clinical Trials
Studies registered on ClinicalTrials.gov (U.S. National Library of Medicine) with the company as lead sponsor or collaborator, newest start first. Values are as registered.
- 2025-11-01: Study NCT07065656; Company role Collaborator; Phase Not applicable; Status Not yet recruiting.
- 2023-03-06: Study NCT05984186; Company role Lead sponsor; Phase Not applicable; Status Completed.
- 2022-01-12: Study NCT04590014; Company role Lead sponsor; Phase Not applicable; Status Terminated.
- 2021-09-02: Study NCT05030012; Company role Lead sponsor; Phase Not applicable; Status Terminated.
| Start date | Study | Company role | Phase | Status | Conditions | Enrollment | Completion date |
|---|---|---|---|---|---|---|---|
| 2025-11-01 | NCT07065656 HVNI vs NIPPV in Type 2 Respiratory Failure | Collaborator Lead: National University Hospital, Singapore | Not applicable | Not yet recruiting | Respiratory Failure; Hypoxia; Hypercapnia | 84 | 2027-12-31 |
| 2023-03-06 | NCT05984186 Effect of High Velocity/Hyperoxic Breathing Therapy on Blood Lactate Decline | Lead sponsor | Not applicable | Completed Results posted | Dyspnea; Lactic Acidosis; Muscle; Breathlessness; Exercise; Recovery | 15 | 2023-12-31 |
| 2022-01-12 | NCT04590014 Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Device Equivalence | Lead sponsor | Not applicable | Terminated Results posted | Dyspnea; Hypercapnia; Respiratory Insufficiency | 5 | 2022-07-15 |
| 2021-09-02 | NCT05030012 Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm Infants | Lead sponsor | Not applicable | Terminated Results posted | Infant, Premature; Neonatal Respiratory Distress; Oxygen Saturation; Bronchopulmonary Dysplasia | 15 | 2023-10-19 |
| 2021-04-15 | NCT04687618 Oxygen Assist Module in Preterm Infants on High Flow Nasal Cannula Support. | Collaborator Lead: South Tees Hospitals NHS Foundation Trust | Not applicable | Unknown | Preterm Birth | 60 | 2023-04-30 |
| 2020-11-11 | NCT04709562 Clinical Stabilization of Hypercapnia: NIPPV v HVNI | Lead sponsor | Not applicable | Completed Results posted | Hypercapnic Respiratory Failure; Chronic Obstructive Pulmonary Disease; Dyspnea; Hypercapnic Acidosis | 68 | 2023-06-22 |
| 2020-10-01 | NCT04512781 Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Cannulae Designs | Lead sponsor | Not applicable | Completed Results posted | Dyspnea; Hypercapnia; Respiratory Insufficiency | 26 | 2022-06-07 |
| 2018-11-21 | NCT03885726 HVNI Ambulation Feasibility Study | Lead sponsor | Not applicable | Completed Results posted | Respiratory Insufficiency; Dyspnea | 32 | 2019-03-11 |
| 2016-12 | NCT02074774 IntellO2 vs Manual Control for Optimizing Oxygenation in Infants | Lead sponsor | Not applicable | Completed | Oxygen Titration in Preterm Infants to Manage Lung Disease | 36 | 2018-01 |
| 2014-09 | NCT02236559 High Flow Therapy for the Treatment of Respiratory Failure in the ED | Lead sponsor | Not applicable | Completed Results posted | Acute Respiratory Failure | 204 | 2017-02 |
| 2013-05 | NCT01860560 Non-Inferiority Trial of Acute HFT Versus nCPAP | Lead sponsor | Not applicable | Withdrawn | Mild-Moderate Obstructive Sleep Disordered Breathing | 0 | 2014-01 |
| 2012-07 | NCT01672242 Assessment of End Expiratory Lung Volumes in Healthy Subjects Using High Flow Oxygen (Vapotherm®) | Collaborator Lead: University of Maryland, Baltimore | Not applicable | Completed Results posted | Healthy Adult Volunteers | 6 | 2014-04 |
| 2009-09 | NCT00990119 High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD) | Lead sponsor | Not applicable | Withdrawn | Pulmonary Disease, Chronic Obstructive; Respiratory Insufficiency | 0 | 2014-04 |