THORATEC CORP Clinical Trials
Studies registered on ClinicalTrials.gov (U.S. National Library of Medicine) with the company as lead sponsor or collaborator, newest start first. Values are as registered.
- 2015-10-13: Study NCT02497950; Company role Collaborator; Phase Observational; Status Completed.
- 2015-06: Study NCT02460770; Company role Collaborator; Phase Phase 1; Status Withdrawn.
- 2015-05: Study NCT02475460; Company role Collaborator; Phase Not applicable; Status Completed.
- 2014-10: Study NCT02279979; Company role Collaborator; Phase Not applicable; Status Terminated.
| Start date | Study | Company role | Phase | Status | Conditions | Enrollment | Completion date |
|---|---|---|---|---|---|---|---|
| 2015-10-13 | NCT02497950 HeartMate 3 ELEVATE™ Registry | Collaborator Lead: Abbott Medical Devices | Observational | Completed Results posted | Heart Failure; Cardiovascular Disease; Ventricular Dysfunction | 540 | 2022-02-28 |
| 2015-06 | NCT02460770 Bone Marrow-derived Mesenchymal Stem Cells (MSC) Administration in Weaning From Left Ventricular Assist Device | Collaborator Lead: University Hospital, Toulouse | Phase 1 | Withdrawn | Chronic Myocardial Ischemia | 0 | 2017-06 |
| 2015-05 | NCT02475460 HeartMate 3™ LIS Study | Collaborator Lead: Abbott Medical Devices | Not applicable | Completed | Heart Failure; Cardiovascular Disease | 13 | 2016-07 |
| 2014-10 | NCT02279979 Thoratec Corporation HeartMate PHP™ Cardiogenic Shock Trial | Collaborator Lead: Abbott Medical Devices | Not applicable | Terminated | Cardiogenic Shock | 9 | 2017-01 |
| 2014-09-02 | NCT02224755 MOMENTUM 3 IDE Clinical Study Protocol | Collaborator Lead: Abbott Medical Devices | Not applicable | Completed Results posted | Advanced Refractory Left Ventricular Heart Failure | 1,028 | 2019-03-26 |
| 2014-09 | NCT02158403 PREVENtion of HeartMate II Pump Thrombosis | Collaborator Lead: Abbott Medical Devices | Not applicable | Completed | HeartMate II Pump Thrombosis | 300 | 2016-06 |
| 2014-08 | NCT02044471 The IMPULSE Study: Pilot | Collaborator Lead: Baylor College of Medicine | Not applicable | Completed | Chronic Heart Failure | 20 | 2016-12 |
| 2014-06 | NCT02170363 HeartMate 3™ CE Mark Clinical Investigation Plan | Collaborator Lead: Abbott Medical Devices | Not applicable | Completed Results posted | Advanced Refractory Left Ventricular Heart Failure | 50 | 2020-03-09 |
| 2014-05 | NCT02156583 Frailty: Prevalence and Response to Left Ventricular Assist Device Therapy in Older Heart Failure Patients | Collaborator Lead: Thomas Jefferson University | Observational | Completed | Systolic Heart Failure | 20 | 2017-07 |
| 2013-10 | NCT01977703 Prospective Randomized Evaluation of an Ultra Conservative Approach to Implantable Defibrillator (ICD) Programming in Patients With a Left Ventricular Assist Device (LVAD). | Collaborator Lead: Vanderbilt University Medical Center | Not applicable | Completed | Heart Failure | 80 | 2016-12 |
| 2013-02 | NCT01707225 Safety Study of Octreotide Injection to Prevent GI Bleeding in Patients With Left Ventricular Assist Device (LVAD) | Collaborator Lead: Virginia Commonwealth University | Phase 1 | Completed Results posted | Gastrointestinal Bleeding | 10 | 2014-10 |
| 2013-01 | NCT01774656 Remission From Stage D Heart Failure | Collaborator Lead: University of Louisville | Phase 4 | Unknown | Heart Failure NYHA Class III; Heart Failure NYHA Class IV | 40 | 2017-12 |
| 2012-05 | NCT01577433 Driveline Silicone Skin Interface Registry | Collaborator Lead: Abbott Medical Devices | Observational | Completed | Driveline Heart-assisted Device Related Infection | 400 | 2018-12 |
| 2012-05 | NCT01485666 Thoratec's Reduce Driveline Trauma Through Stabilization and Exit Site Management Study | Collaborator Lead: Abbott Medical Devices | Observational | Completed | Left Ventricular Assist Device; Percutaneous Lead Management | 50 | 2013-08 |
| 2012-04-05 | NCT01571037 Inhaled Milrinone Use in Patients Receiving HeartMate II LVAD: A Pilot Study | Collaborator Lead: University of Nebraska | Phase 1 | Completed | End Stage Heart Disease; Right Ventricular Dysfunction | 10 | 2014-02-21 |
| 2011-10 | NCT01452802 Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device (LVAD) and Medical Management | Collaborator Lead: Abbott Medical Devices | Observational | Completed | Heart Failure | 200 | 2016-06 |
| 2009-09 | NCT01568424 CentriMag RVAS U.S. Post-approval Study Protocol | Collaborator Lead: Abbott Medical Devices | Not applicable | Completed Results posted | Right Ventricular Failure | 25 | 2014-06 |
| 2009-07 | NCT00983190 BeneMACS Study:HeartMate 2 (HM2)Left Ventricular Assist Device (LVAD) Survival in Non Transplant Patients is Equal/Better Than Results in Medical Literature | Collaborator Lead: Abbott Medical Devices | Not applicable | Completed | Heart Failure | 10 | 2013-05 |
| 2009-06 | NCT01171950 CentriMag Ventricular Assist System in Treating Failure-to-Wean From Cardiopulmonary Bypass for Pediatric Patients | Collaborator Lead: Abbott Medical Devices | Not applicable | Withdrawn | Heart Failure | 0 | 2012-12 |
| 2008-10 | NCT00819793 CentriMag Ventricular Assist System in Treating Failure-to-Wean From Cardiopulmonary Bypass | Collaborator Lead: Abbott Medical Devices | Not applicable | Completed Results posted | Heart Failure | 32 | 2013-09 |
| 2007-07 | NCT00585546 Harefield Recovery Protocol Study for Patients With Refractory Chronic Heart Failure | Collaborator Lead: Francis D. Pagani | Phase 1 | Terminated Results posted | Heart Failure; Dilated Cardiomyopathy | 18 | 2010-03 |
| 2005-03 | NCT00121472 Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Bridge to Cardiac Transplantation | Collaborator Lead: Abbott Medical Devices | Not applicable | Completed Results posted | Heart Failure, Congestive; Ventricular Dysfunction; Cardiomyopathies | 194 | 2010-05 |
| 2005-02 | NCT00121485 Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Destination Therapy | Collaborator Lead: Abbott Medical Devices | Not applicable | Completed Results posted | Heart Failure, Congestive; Ventricular Dysfunction; Cardiomyopathies | 200 | 2012-01 |