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REGENERON PHARMACEUTICALS, INC. (REGN) Forms 3, 4 and 5: Stock Options

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REGENERON PHARMACEUTICALS, INC. Forms 3, 4 and 5: Stock Options

Statements of beneficial ownership filed with the SEC by officers, directors and 10% owners: 19 rows in 2026. Transaction codes are the SEC's. Shares and prices are split-adjusted; the as-filed figure is underneath.

  • 2026-09-02: Reporting owner Guarini Kathryn; Form 4; Security Non-Qualified Stock Option (right to buy); Transaction M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3.
  • 2026-08-19: Reporting owner LAROSA JOSEPH J; Form 4; Security Non-Qualified Stock Option (right to buy); Transaction M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3.
  • 2026-08-18: Reporting owner Fenimore Christopher R.; Form 4; Security Non-Qualified Stock Option (right to buy); Transaction M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3.
  • 2026-08-10: Reporting owner Guarini Kathryn; Form 4; Security Non-Qualified Stock Option (right to buy); Transaction M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3.

REGN insiders transactions against the stock price

Blue: Split-adjusted close · Orange: Cumulative dividend-reinvested close

$570.63$631.81$699.56$774.58$857.64$949.602025-11-062026-11-06$458.92$561.81$687.77$841.97$1,030.75$1,261.852021-11-082026-11-06$259.79$356.37$488.85$670.58$919.88$1,261.852016-11-072026-11-06$11.45$29.32$75.10$192.35$492.66$1,261.852006-11-062026-11-06$2.85$9.64$32.61$110.29$373.06$1,261.851991-04-022026-11-062006-01-03: 8 award or grants at $15.90 close — SING GEORGE L, SHOOTER ERIC M, RYAN ARTHUR F and 4 more2006-01-03: 1 option exercise at $15.90 close — SHOOTER ERIC M2006-01-06: 19 option exercises at $17.00 close — GILMAN ALFRED G2006-01-09: 5 option exercises at $17.13 close — BROWN MICHAEL S, SING GEORGE L2006-02-01: 6 option exercises at $15.77 close — BAKER CHARLES A2006-02-03: 2 option exercises at $16.19 close — STAHL NEIL2006-03-09: 1 option exercise at $16.30 close — SHOOTER ERIC M2006-09-01: 3 option exercises at $15.82 close · Value $316.40K estimated — RUPP RANDALL2006-10-02: 2 award or grants at $15.67 close — Powchik Peter2006-10-17: 1 option exercise at $17.99 close · Value $179.90K estimated — BROWN MICHAEL S2006-10-31: 21 option exercises at $20.05 close · Value $4.09M estimated — RUPP RANDALL, STAHL NEIL2006-11-06: 5 option exercises at $23.22 close · Value $4.20M estimated — GOLDBERG MURRAY A, SCHLEIFER LEONARD S2006-11-07: 3 option exercises at $24.24 close · Value $246.67K estimated — GOLDBERG MURRAY A2006-11-20: 4 option exercises at $23.85 close · Value $147.87K estimated — GOLDBERG MURRAY A2006-11-21: 9 option exercises at $23.41 close · Value $234.10K estimated — SHOOTER ERIC M2006-12-18: 16 award or grants at $20.06 close — YANCOPOULOS GEORGE, VAGELOS P ROY, STAHL NEIL and 6 more2007-01-03: 7 award or grants at $19.81 close — SING GEORGE L, SHOOTER ERIC M, RYAN ARTHUR F and 4 more2007-01-03: 8 option exercises at $19.81 close · Value $594.30K estimated — YANCOPOULOS GEORGE2007-01-30: 1 option exercise at $20.59 close · Value $68.63K estimated — VAGELOS P ROY2007-02-16: 16 option exercises at $22.00 close · Value $220.00K estimated — BAKER CHARLES A2007-02-26: 2 award or grants at $21.18 close — Terifay Robert J2007-02-26: 19 option exercises at $21.18 close · Value $211.80K estimated — GILMAN ALFRED G2007-04-09: 8 option exercises at $23.96 close · Value $228.96K estimated — YANCOPOULOS GEORGE2007-04-13: 20 option exercises at $25.04 close · Value $3.24M estimated — RUPP RANDALL, GOLDBERG MURRAY A, YANCOPOULOS GEORGE2007-04-20: 2 option exercises at $25.90 close · Value $932.40K estimated — GOLDBERG MURRAY A, STAHL NEIL2007-04-25: 2 option exercises at $27.36 close · Value $552.37K estimated — GOLDBERG MURRAY A2007-09-07: 2 award or grants at $21.25 close — Van Plew Daniel P2007-10-02: 5 option exercises at $18.41 close · Value $184.10K estimated — SHOOTER ERIC M2007-11-02: 8 option exercises at $21.00 close · Value $130.39K estimated — McCorkle Douglas S2007-11-05: 20 option exercises at $20.28 close · Value $304.20K estimated — GOLDSTEIN JOSEPH L, BROWN MICHAEL S2007-12-17: 19 award or grants at $21.36 close · Value $24.72M estimated — Powchik Peter, YANCOPOULOS GEORGE, Van Plew Daniel P and 8 more2007-12-20: 1 option exercise at $22.96 close · Value $858.02K estimated — SCHLEIFER LEONARD S2008-01-02: 7 award or grants at $23.56 close · Value $2.47M estimated — SING GEORGE L, SHOOTER ERIC M, RYAN ARTHUR F and 4 more2008-01-22: 1 option exercise at $24.77 close · Value $123.85K estimated — GOLDSTEIN JOSEPH L2008-02-15: 15 option exercises at $18.90 close · Value $189.00K estimated — BAKER CHARLES A2008-02-20: 1 option exercise at $18.54 close · Value $185.40K estimated — GILMAN ALFRED G2008-02-27: 1 option exercise at $18.90 close · Value $125.99K estimated — VAGELOS P ROY2008-05-30: 7 option exercises at $19.90 close · Value $298.50K estimated — SHOOTER ERIC M2008-08-20: 1 option exercise at $21.27 close · Value $741.05K estimated — ROBERTS WILLIAM2008-09-09: 1 option exercise at $18.52 close · Value $92.60K estimated — BROWN MICHAEL S2008-09-16: 1 option exercise at $21.64 close · Value $541.00K estimated — ROBERTS WILLIAM2008-09-19: 4 option exercises at $23.07 close · Value $230.52K estimated — KOLINSKI STUART2008-09-29: 2 option exercises at $21.88 close · Value $2.14M estimated — STAHL NEIL, SCHLEIFER LEONARD S2008-10-01: 44 option exercises at $22.82 close · Value $372.70K estimated — McCorkle Douglas S2008-12-15: 1 option exercise at $15.83 close — GOLDBERG MURRAY A2008-12-16: 2 option exercises at $17.04 close · Value $1.70M estimated — YANCOPOULOS GEORGE2008-12-17: 22 award or grants at $16.90 close · Value $16.48M estimated — SCHLEIFER LEONARD S, Terifay Robert J, KOLINSKI STUART and 8 more2008-12-19: 2 option exercises at $18.91 close · Value $2.46M estimated — VAGELOS P ROY2009-01-02: 7 award or grants at $18.70 close · Value $1.96M estimated — SING GEORGE L, RYAN ARTHUR F, GILMAN ALFRED G and 4 more2009-01-02: 1 option exercise at $18.70 close · Value $24.31K estimated — GOLDBERG MURRAY A2009-01-21: 1 option exercise at $16.40 close · Value $164.00K estimated — GILMAN ALFRED G2009-02-20: 1 option exercise at $18.15 close · Value $181.50K estimated — BAKER CHARLES A2009-02-23: 1 option exercise at $17.15 close · Value $85.75K estimated — BROWN MICHAEL S2009-04-27: 1 option exercise at $12.66 close · Value $191.93K estimated — ROBERTS WILLIAM2009-07-24: 2 option exercises at $20.75 close · Value $2.08M estimated — STAHL NEIL2009-08-12: 3 option exercises at $22.72 close · Value $151.45K estimated — ROBERTS WILLIAM2009-09-01: 3 option exercises at $23.11 close · Value $327.38K estimated — ROBERTS WILLIAM2009-10-27: 1 option exercise at $17.20 close · Value $543.71K estimated — SCHLEIFER LEONARD S2009-10-29: 1 option exercise at $16.24 close · Value $75.40K estimated — GOLDBERG MURRAY A2009-12-03: 1 option exercise at $19.00 close · Value $1.90M estimated — YANCOPOULOS GEORGE2009-12-08: 1 option exercise at $18.93 close · Value $3.55M estimated — VAGELOS P ROY2009-12-15: 1 option exercise at $20.22 close · Value $3.03M estimated — SCHLEIFER LEONARD S2009-12-18: 22 award or grants at $21.41 close · Value $17.30M estimated — Dworkin Peter, GOLDBERG MURRAY A, KOLINSKI STUART and 9 more2009-12-21: 5 option exercises at $21.95 close · Value $53.91K estimated — McCorkle Douglas S2009-12-28: 2 option exercises at $24.40 close · Value $305.00K estimated — ROBERTS WILLIAM2010-01-04: 7 award or grants at $24.63 close · Value $2.59M estimated — GILMAN ALFRED G, SING GEORGE L, SHOOTER ERIC M and 4 more2010-01-05: 1 award or grant at $25.10 close · Value $320.98K estimated — GOLDBERG MURRAY A2010-01-05: 3 option exercises at $25.10 close · Value $1.30M estimated — GOLDBERG MURRAY A, SHOOTER ERIC M2010-01-21: 1 option exercise at $26.14 close · Value $392.10K estimated — SHOOTER ERIC M2010-01-27: 2 option exercises at $27.03 close · Value $293.52K estimated — KOLINSKI STUART, ROBERTS WILLIAM2010-02-02: 7 option exercises at $28.00 close · Value $845.29K estimated — ROBERTS WILLIAM, McCorkle Douglas S, KOLINSKI STUART2010-02-03: 3 option exercises at $28.65 close · Value $615.98K estimated — GOLDBERG MURRAY A, ROBERTS WILLIAM2010-02-17: 1 option exercise at $30.46 close · Value $456.90K estimated — SHOOTER ERIC M2010-03-22: 2 award or grants at $24.36 close · Value $2.44M estimated — Aberman Michael S2010-05-13: 1 option exercise at $28.41 close · Value $142.05K estimated — SHOOTER ERIC M2010-05-14: 1 option exercise at $27.37 close · Value $136.85K estimated — GOLDSTEIN JOSEPH L2010-05-18: 1 option exercise at $28.02 close · Value $140.10K estimated — BROWN MICHAEL S2010-05-27: 1 option exercise at $27.90 close · Value $139.50K estimated — GILMAN ALFRED G2010-06-02: 1 option exercise at $30.28 close · Value $151.40K estimated — BAKER CHARLES A2010-06-03: 2 option exercises at $30.18 close · Value $980.85K estimated — KOLINSKI STUART, GOLDBERG MURRAY A2010-06-09: 1 option exercise at $25.04 close · Value $125.20K estimated — SING GEORGE L2010-10-04: 1 option exercise at $28.27 close · Value $282.70K estimated — GOLDSTEIN JOSEPH L2010-10-06: 1 option exercise at $29.18 close · Value $145.90K estimated — BROWN MICHAEL S2010-11-12: 1 award or grant at $25.29 close · Value $632.25K estimated — POON CHRISTINE A2010-11-23: 3 option exercises at $29.99 close · Value $524.83K estimated — GOLDSTEIN JOSEPH L, SHOOTER ERIC M2010-12-14: 18 award or grants at $30.61 close · Value $23.59M estimated — YANCOPOULOS GEORGE, Van Plew Daniel P, VAGELOS P ROY and 7 more2010-12-16: 5 option exercises at $32.03 close · Value $2.16M estimated — GOLDBERG MURRAY A, Van Plew Daniel P, GOLDSTEIN JOSEPH L2010-12-17: 1 option exercise at $33.06 close · Value $165.30K estimated — BROWN MICHAEL S2010-12-23: 1 option exercise at $33.50 close · Value $134.00K estimated — GOLDBERG MURRAY A2011-01-03: 8 award or grants at $33.82 close · Value $4.06M estimated — SING GEORGE L, SHOOTER ERIC M, RYAN ARTHUR F and 5 more2011-01-06: 2 option exercises at $34.31 close · Value $686.20K estimated — GOLDBERG MURRAY A2011-01-07: 1 option exercise at $34.10 close · Value $341.00K estimated — ROBERTS WILLIAM2011-01-14: 1 option exercise at $34.50 close · Value $40.99K estimated — ROBERTS WILLIAM2011-01-18: 8 option exercises at $35.43 close · Value $2.44M estimated — ROBERTS WILLIAM, BROWN MICHAEL S, SHOOTER ERIC M and 1 more2011-01-26: 1 option exercise at $34.47 close · Value $344.70K estimated — GOLDSTEIN JOSEPH L2011-02-10: 1 option exercise at $36.49 close · Value $182.45K estimated — GOLDSTEIN JOSEPH L2011-02-11: 1 option exercise at $35.31 close · Value $706.20K estimated — GOLDBERG MURRAY A2011-02-14: 1 option exercise at $37.71 close · Value $188.55K estimated — Terifay Robert J2011-02-17: 4 option exercises at $37.67 close · Value $2.40M estimated — Terifay Robert J, GOLDBERG MURRAY A2011-03-04: 1 option exercise at $38.00 close · Value $231.76K estimated — Terifay Robert J2011-03-09: 7 option exercises at $39.84 close · Value $2.27M estimated — SHOOTER ERIC M, McCorkle Douglas S, GOLDSTEIN JOSEPH L and 1 more2011-03-17: 2 option exercises at $38.83 close · Value $1.16M estimated — GILMAN ALFRED G2011-03-21: 2 option exercises at $39.92 close · Value $423.15K estimated — McCorkle Douglas S2011-03-30: 2 option exercises at $44.68 close · Value $567.08K estimated — BROWN MICHAEL S, STAHL NEIL2011-04-04: 1 option exercise at $45.43 close · Value $4.19M estimated — STAHL NEIL2011-05-04: 1 option exercise at $48.00 close · Value $240.00K estimated — GOLDSTEIN JOSEPH L2011-07-01: 8 option exercises at $57.75 close · Value $2.66M estimated — GOLDSTEIN JOSEPH L, BROWN MICHAEL S, BAKER CHARLES A2011-07-25: 1 option exercise at $55.65 close · Value $1.39M estimated — Powchik Peter2011-07-27: 1 award or grant at $52.65 close · Value $206.34K estimated — GOLDBERG MURRAY A2011-07-27: 1 option exercise at $52.65 close · Value $1.16M estimated — GOLDBERG MURRAY A2011-08-01: 1 option exercise at $52.66 close · Value $797.48K estimated — Powchik Peter2011-08-04: 1 option exercise at $47.72 close · Value $228.29K estimated — Van Plew Daniel P2011-08-10: 1 option exercise at $47.10 close · Value $188.40K estimated — BAKER CHARLES A2011-08-15: 1 award or grant at $58.17 close · Value $179.40K estimated — GOLDBERG MURRAY A2011-08-15: 1 option exercise at $58.17 close · Value $872.55K estimated — GOLDBERG MURRAY A2011-08-31: 1 option exercise at $59.03 close · Value $18.45M estimated — VAGELOS P ROY2011-09-01: 2 award or grants at $59.46 close · Value $4.76M estimated — LAROSA JOSEPH J2011-09-02: 1 option exercise at $64.78 close · Value $269.87K estimated — Aberman Michael S2011-09-06: 2 award or grants at $68.55 close · Value $529.27K estimated — GOLDBERG MURRAY A2011-09-06: 14 option exercises at $68.55 close · Value $10.56M estimated — ROBERTS WILLIAM, STAHL NEIL, GOLDBERG MURRAY A and 1 more2011-09-07: 1 option exercise at $71.27 close · Value $356.35K estimated — BROWN MICHAEL S2011-09-08: 1 award or grant at $72.19 close · Value $300.89K estimated — GOLDBERG MURRAY A2011-09-08: 2 option exercises at $72.19 close · Value $2.24M estimated — GOLDBERG MURRAY A, BROWN MICHAEL S2011-09-14: 8 option exercises at $63.51 close · Value $7.30M estimated — RYAN ARTHUR F2011-09-21: 1 option exercise at $70.28 close · Value $351.40K estimated — BROWN MICHAEL S2011-10-04: 3 option exercises at $57.55 close · Value $791.25K estimated — GOLDBERG MURRAY A2011-10-10: 2 option exercises at $66.00 close · Value $1.94M estimated — Terifay Robert J2011-10-14: 1 option exercise at $63.95 close · Value $639.50K estimated — GOLDSTEIN JOSEPH L2011-11-14: 1 option exercise at $53.99 close · Value $927.66K estimated — STAHL NEIL2011-11-18: 1 award or grant at $49.81 close · Value $1.25M estimated — Tessier-Lavigne Marc2011-11-22: 1 option exercise at $56.73 close · Value $850.95K estimated — SING GEORGE L2011-11-30: 2 option exercises at $59.42 close · Value $11.88M estimated — YANCOPOULOS GEORGE2011-12-16: 27 award or grants at $53.00 close · Value $67.02M estimated — GOLDBERG MURRAY A, YANCOPOULOS GEORGE, STAHL NEIL and 9 more2011-12-16: 1 option exercise at $53.00 close · Value $13.25M estimated — SCHLEIFER LEONARD S2011-12-20: 1 option exercise at $55.03 close · Value $137.57K estimated — GOLDBERG MURRAY A2012-01-03: 9 award or grants at $56.43 close · Value $7.62M estimated — GILMAN ALFRED G, SING GEORGE L, SHOOTER ERIC M and 6 more2012-01-10: 9 option exercises at $74.44 close · Value $7.44M estimated — Terifay Robert J, ROBERTS WILLIAM, GOLDSTEIN JOSEPH L2012-01-19: 1 award or grant at $79.76 close · Value $831.42K estimated — GOLDBERG MURRAY A2012-01-19: 1 option exercise at $79.76 close · Value $3.25M estimated — GOLDBERG MURRAY A2012-01-31: 2 award or grants at $90.86 close · Value $929.23K estimated — GOLDBERG MURRAY A2012-01-31: 3 option exercises at $90.86 close · Value $6.11M estimated — GOLDBERG MURRAY A, Terifay Robert J2012-02-06: 3 option exercises at $101.14 close · Value $4.14M estimated — GOLDBERG MURRAY A2012-02-13: 2 option exercises at $114.65 close · Value $7.64M estimated — STAHL NEIL2012-02-14: 3 award or grants at $110.10 close · Value $8.04M estimated — SCHLEIFER LEONARD S2012-02-14: 12 option exercises at $110.10 close · Value $69.36M estimated — McCorkle Douglas S, SCHLEIFER LEONARD S, GILMAN ALFRED G and 2 more2012-02-15: 2 award or grants at $108.64 close · Value $1.13M estimated — YANCOPOULOS GEORGE2012-02-15: 2 option exercises at $108.64 close · Value $14.49M estimated — YANCOPOULOS GEORGE2012-02-21: 4 option exercises at $99.26 close · Value $10.91M estimated — Powchik Peter2012-03-01: 5 option exercises at $107.56 close · Value $2.15M estimated — BROWN MICHAEL S2012-03-15: 3 option exercises at $115.75 close · Value $1.16M estimated — GOLDSTEIN JOSEPH L2012-03-26: 1 option exercise at $119.96 close · Value $599.80K estimated — GOLDSTEIN JOSEPH L2012-04-17: 1 option exercise at $123.45 close · Value $258.01K estimated — BAKER CHARLES A2012-04-19: 1 option exercise at $125.99 close · Value $1.63M estimated — BAKER CHARLES A2012-04-27: 2 option exercises at $140.01 close · Value $4.93M estimated — Van Plew Daniel P2012-04-30: 1 option exercise at $135.26 close · Value $1.69M estimated — Aberman Michael S2012-05-02: 2 award or grants at $137.31 close · Value $1.20M estimated — GOLDBERG MURRAY A2012-05-02: 2 option exercises at $137.31 close · Value $7.47M estimated — GOLDBERG MURRAY A2012-05-18: 1 option exercise at $120.23 close · Value $240.46K estimated — SHOOTER ERIC M2012-05-21: 4 option exercises at $126.17 close · Value $4.32M estimated — GOLDBERG MURRAY A, SHOOTER ERIC M2012-05-24: 1 option exercise at $129.71 close · Value $64.86K estimated — Aberman Michael S2012-06-18: 1 award or grant at $116.93 close — STAHL NEIL2012-06-18: 1 option exercise at $116.93 close · Value $11.12M estimated — STAHL NEIL2012-07-25: 1 option exercise at $128.84 close · Value $1.93M estimated — Powchik Peter2012-07-26: 1 option exercise at $135.64 close · Value $678.20K estimated — SING GEORGE L2012-07-27: 3 option exercises at $136.90 close · Value $6.96M estimated — Terifay Robert J2012-08-01: 2 option exercises at $134.01 close · Value $2.01M estimated — Powchik Peter2012-08-06: 1 option exercise at $137.45 close · Value $412.35K estimated — BROWN MICHAEL S2012-08-07: 1 option exercise at $139.48 close · Value $2.09M estimated — GILMAN ALFRED G2012-08-22: 1 option exercise at $139.00 filed · Value $695.00K — SING GEORGE L2012-08-23: 3 option exercises at $142.00 filed · Value $2.87M estimated — McCorkle Douglas S, SING GEORGE L2012-08-28: 1 award or grant at $146.77 close · Value $883.12K estimated — STAHL NEIL2012-08-28: 1 option exercise at $146.77 close · Value $5.87M estimated — STAHL NEIL2012-09-05: 1 option exercise at $149.46 close · Value $192.21K estimated — BAKER CHARLES A2012-09-06: 1 option exercise at $152.45 close · Value $2.09M estimated — BAKER CHARLES A2012-09-18: 1 option exercise at $147.07 close · Value $2.21M estimated — Powchik Peter2012-10-25: 2 option exercises at $155.23 close · Value $4.97M estimated — Van Plew Daniel P, BROWN MICHAEL S2012-10-26: 1 option exercise at $149.25 close · Value $447.75K estimated — BROWN MICHAEL S2012-11-13: 2 option exercises at $148.08 close · Value $1.21M estimated — GOLDBERG MURRAY A2012-11-14: 1 option exercise at $147.55 close · Value $1.03M estimated — BROWN MICHAEL S2012-11-16: 1 option exercise at $157.69 close · Value $6.90M estimated — SCHLEIFER LEONARD S2012-11-20: 2 option exercises at $172.87 close · Value $9.42M estimated — STAHL NEIL2012-11-21: 1 option exercise at $174.55 close · Value $3.49M estimated — Terifay Robert J2012-11-23: 1 option exercise at $176.08 close · Value $55.03M estimated — VAGELOS P ROY2012-11-26: 5 option exercises at $174.39 close · Value $2.62M estimated — BAKER CHARLES A2012-11-29: 1 option exercise at $187.74 close · Value $1.56M estimated — Aberman Michael S2012-11-30: 2 option exercises at $176.55 close · Value $1.67M estimated — STAHL NEIL2012-12-10: 1 option exercise at $184.69 close · Value $1.39M estimated — Aberman Michael S2012-12-14: 19 award or grants at $179.71 close · Value $326.50M estimated — Van Plew Daniel P, GOLDBERG MURRAY A, YANCOPOULOS GEORGE and 9 more2012-12-17: 7 option exercises at $179.40 close · Value $4.16M estimated — GOLDBERG MURRAY A, YANCOPOULOS GEORGE, STAHL NEIL and 1 more2012-12-18: 10 option exercises at $180.02 close · Value $9.01M estimated — Powchik Peter, McCorkle Douglas S, Aberman Michael S and 1 more2012-12-19: 6 option exercises at $175.65 close · Value $8.93M estimated — YANCOPOULOS GEORGE2012-12-20: 1 option exercise at $172.84 close · Value $354.32K estimated — Van Plew Daniel P2013-01-02: 9 award or grants at $181.20 close · Value $24.46M estimated — SING GEORGE L, GILMAN ALFRED G, BAKER CHARLES A and 6 more2013-01-02: 1 option exercise at $181.20 close · Value $5.44M estimated — Powchik Peter2013-01-04: 2 option exercises at $181.07 close · Value $905.35K estimated — GOLDSTEIN JOSEPH L2013-01-09: 3 option exercises at $183.40 close · Value $1.97M estimated — Powchik Peter, GOLDSTEIN JOSEPH L2013-03-21: 4 option exercises at $171.33 close · Value $2.57M estimated — BROWN MICHAEL S2013-04-01: 1 option exercise at $178.51 close · Value $892.55K estimated — GOLDSTEIN JOSEPH L2013-04-11: 1 option exercise at $208.35 close · Value $1.22M estimated — McCorkle Douglas S2013-05-01: 1 option exercise at $237.29 close · Value $1.39M estimated — McCorkle Douglas S2013-05-06: 1 award or grant at $262.75 close · Value $2.52M estimated — YANCOPOULOS GEORGE2013-05-06: 31 option exercises at $262.75 close · Value $78.02M estimated — Aberman Michael S, GILMAN ALFRED G, SHOOTER ERIC M and 3 more2013-05-07: 2 option exercises at $262.19 close · Value $4.44M estimated — Terifay Robert J2013-05-10: 1 award or grant at $273.50 close · Value $1.24M estimated — STAHL NEIL2013-05-10: 2 option exercises at $273.50 close · Value $16.53M estimated — STAHL NEIL, SING GEORGE L2013-05-13: 1 option exercise at $280.51 close · Value $3.51M estimated — Aberman Michael S2013-05-15: 2 option exercises at $274.11 close · Value $4.11M estimated — BROWN MICHAEL S2013-05-20: 9 option exercises at $263.64 close · Value $39.01M estimated — GOLDBERG MURRAY A2013-05-21: 2 option exercises at $259.96 close · Value $1.05M estimated — GOLDBERG MURRAY A2013-06-10: 1 option exercise at $252.83 close · Value $3.79M estimated — BAKER CHARLES A2013-06-17: 1 option exercise at $232.71 close · Value $907.57K estimated — Aberman Michael S2013-08-01: 1 option exercise at $278.29 close · Value $1.39M estimated — GOLDBERG MURRAY A2013-08-22: 4 option exercises at $237.35 close · Value $7.12M estimated — RYAN ARTHUR F2013-09-09: 1 award or grant at $276.80 close · Value $22.14M estimated — Landry Robert E2013-09-17: 1 option exercise at $296.62 close — Van Plew Daniel P2013-09-18: 1 award or grant at $309.17 close — SCHLEIFER LEONARD S2013-09-18: 3 option exercises at $309.17 close — VAGELOS P ROY, SCHLEIFER LEONARD S, ROBERTS WILLIAM2013-09-25: 1 option exercise at $292.23 close — BROWN MICHAEL S2013-09-26: 1 option exercise at $305.53 close — BROWN MICHAEL S2013-09-30: 1 option exercise at $312.87 close — BAKER CHARLES A2013-10-01: 2 option exercises at $316.63 close — SCHLEIFER LEONARD S2013-11-26: 1 option exercise at $295.12 close — SING GEORGE L2013-12-12: 1 option exercise at $274.00 close — YANCOPOULOS GEORGE2013-12-13: 18 award or grants at $269.59 close — Powchik Peter, LAROSA JOSEPH J, McCorkle Douglas S and 8 more2013-12-16: 3 option exercises at $268.45 close — Powchik Peter2013-12-18: 5 option exercises at $271.72 close — Powchik Peter, GOLDBERG MURRAY A, STAHL NEIL and 2 more2013-12-19: 1 option exercise at $270.55 close — YANCOPOULOS GEORGE2013-12-24: 1 option exercise at $275.69 close — Powchik Peter2013-12-31: 1 option exercise at $275.24 close — Powchik Peter2014-01-02: 9 award or grants at $274.59 close — SHOOTER ERIC M, BAKER CHARLES A, Tessier-Lavigne Marc and 6 more2014-01-14: 1 option exercise at $300.32 close — GILMAN ALFRED G2014-02-11: 1 award or grant at $326.52 close — YANCOPOULOS GEORGE2014-02-11: 3 option exercises at $326.52 close — YANCOPOULOS GEORGE, GILMAN ALFRED G, McCorkle Douglas S2014-02-12: 6 option exercises at $320.38 close — SHOOTER ERIC M, STAHL NEIL2014-02-14: 3 option exercises at $323.99 close — Aberman Michael S, SING GEORGE L, Terifay Robert J2014-02-20: 6 option exercises at $327.62 close — GOLDBERG MURRAY A, McCorkle Douglas S2014-02-21: 4 option exercises at $334.98 close — SING GEORGE L, GILMAN ALFRED G2014-02-24: 3 option exercises at $347.62 close — GOLDBERG MURRAY A2014-02-26: 1 option exercise at $336.48 close — BROWN MICHAEL S2014-02-27: 6 option exercises at $338.54 close — VAGELOS P ROY2014-03-17: 1 option exercise at $328.09 close — BROWN MICHAEL S2014-03-24: 1 option exercise at $306.37 close — BAKER CHARLES A2014-04-04: 1 award or grant at $285.34 close — INGRAM ROBERT ALEXANDER2014-05-22: 1 option exercise at $298.28 close — Van Plew Daniel P2014-08-06: 2 option exercises at $340.69 close — STAHL NEIL, Van Plew Daniel P2014-08-07: 1 option exercise at $338.73 close — VAGELOS P ROY2014-08-15: 1 option exercise at $348.62 close — BROWN MICHAEL S2014-08-18: 2 option exercises at $349.46 close — Aberman Michael S, McCorkle Douglas S2014-08-22: 1 option exercise at $340.79 close — Aberman Michael S2014-08-26: 2 option exercises at $354.05 close — VAGELOS P ROY, Tessier-Lavigne Marc2014-08-27: 4 option exercises at $350.01 close — YANCOPOULOS GEORGE, McCorkle Douglas S, Tessier-Lavigne Marc2014-10-23: 1 option exercise at $393.96 close — GOLDBERG MURRAY A2014-10-24: 1 option exercise at $402.50 close — BROWN MICHAEL S2014-10-27: 1 award or grant at $407.16 close — SCHLEIFER LEONARD S2014-10-27: 2 option exercises at $407.16 close — SCHLEIFER LEONARD S2014-11-12: 2 option exercises at $401.11 close — Van Plew Daniel P, GOLDSTEIN JOSEPH L2014-11-17: 1 option exercise at $399.65 close — Terifay Robert J2014-11-18: 1 option exercise at $413.22 close — STAHL NEIL2014-11-24: 3 option exercises at $409.75 close — GILMAN ALFRED G2014-12-15: 4 option exercises at $401.01 close — McCorkle Douglas S2014-12-16: 19 award or grants at $396.13 close — VAGELOS P ROY, STAHL NEIL, SCHLEIFER LEONARD S and 9 more2014-12-16: 5 option exercises at $396.13 close — STAHL NEIL, GOLDBERG MURRAY A, YANCOPOULOS GEORGE and 1 more2014-12-17: 1 option exercise at $410.99 close — McCorkle Douglas S2014-12-18: 1 option exercise at $423.79 close — Van Plew Daniel P2014-12-19: 1 option exercise at $427.64 close — Powchik Peter2014-12-31: 1 option exercise at $410.25 close — Powchik Peter2015-01-02: 9 award or grants at $410.16 close — RYAN ARTHUR F, Tessier-Lavigne Marc, BAKER CHARLES A and 6 more2015-02-13: 1 option exercise at $402.40 close — Aberman Michael S2015-02-20: 8 option exercises at $423.78 close — SING GEORGE L, Van Plew Daniel P, BROWN MICHAEL S and 2 more2015-02-23: 2 option exercises at $425.11 close — Aberman Michael S, Terifay Robert J2015-02-26: 1 option exercise at $419.87 close — Tessier-Lavigne Marc2015-03-16: 3 option exercises at $451.77 close — Terifay Robert J, LAROSA JOSEPH J2015-03-17: 2 option exercises at $467.80 close — Aberman Michael S2015-03-25: 2 option exercises at $453.99 close — LAROSA JOSEPH J, BAKER CHARLES A2015-04-08: 1 option exercise at $453.19 close — Landry Robert E2015-05-15: 1 option exercise at $489.01 close — BROWN MICHAEL S2015-05-22: 5 option exercises at $513.88 close — INGRAM ROBERT ALEXANDER, Van Plew Daniel P, McCorkle Douglas S2015-05-27: 1 option exercise at $515.37 close — SING GEORGE L2015-08-05: 8 option exercises at $592.40 close — Terifay Robert J, Van Plew Daniel P, Landry Robert E and 2 more2015-08-06: 1 option exercise at $582.47 close — GILMAN ALFRED G2015-08-11: 1 option exercise at $566.99 close — POON CHRISTINE A2015-08-13: 5 option exercises at $574.10 close — Powchik Peter2015-09-01: 1 option exercise at $496.42 close — LAROSA JOSEPH J2015-09-02: 1 option exercise at $518.78 close — SCHLEIFER LEONARD S2015-09-17: 1 option exercise at $550.97 close — BAKER CHARLES A2015-09-21: 1 option exercise at $529.38 close — BROWN MICHAEL S2015-10-30: 1 option exercise at $557.39 close — YANCOPOULOS GEORGE2015-11-05: 2 option exercises at $564.16 close — STAHL NEIL2015-11-06: 2 option exercises at $562.00 close — Van Plew Daniel P2015-11-18: 1 option exercise at $587.09 close — SING GEORGE L2015-12-10: 1 option exercise at $548.17 close — BROWN MICHAEL S2015-12-16: 11 award or grants at $559.67 close — Aberman Michael S, Landry Robert E, LAROSA JOSEPH J and 8 more2015-12-16: 5 option exercises at $559.67 close — McCorkle Douglas S, Powchik Peter, STAHL NEIL and 2 more2015-12-17: 1 option exercise at $551.49 close — Aberman Michael S2015-12-29: 1 option exercise at $550.21 close — McCorkle Douglas S2016-01-04: 7 award or grants at $516.55 close — BROWN MICHAEL S, GOLDSTEIN JOSEPH L, RYAN ARTHUR F and 4 more2016-03-21: 1 option exercise at $371.04 close — GOLDSTEIN JOSEPH L2016-04-01: 1 option exercise at $405.25 close — GOLDSTEIN JOSEPH L2016-04-06: 1 option exercise at $427.20 close — GOLDSTEIN JOSEPH L2016-05-12: 1 option exercise at $365.64 close — VAGELOS P ROY2016-05-17: 1 option exercise at $386.38 close — Van Plew Daniel P2016-07-29: 1 option exercise at $425.12 close — GOLDSTEIN JOSEPH L2016-09-09: 2 award or grants at $384.43 close — Zoghbi Huda Y, Bassler Bonnie L2016-11-07: 1 option exercise at $365.39 close — VAGELOS P ROY2016-11-14: 1 option exercise at $444.52 close — GOLDSTEIN JOSEPH L2016-12-12: 1 option exercise at $387.10 close — BAKER CHARLES A2016-12-15: 2 option exercises at $378.01 close — YANCOPOULOS GEORGE, SCHLEIFER LEONARD S2016-12-16: 10 award or grants at $378.85 close — VAGELOS P ROY, STAHL NEIL, LAROSA JOSEPH J and 7 more2017-01-03: 9 award or grants at $379.70 close — BAKER CHARLES A, Tessier-Lavigne Marc, POON CHRISTINE A and 6 more2017-01-03: 1 option exercise at $379.70 close — SING GEORGE L2017-01-27: 1 award or grant at $346.50 close — COLES N ANTHONY2017-03-29: 1 option exercise at $394.14 close — BROWN MICHAEL S2017-05-12: 1 option exercise at $442.05 close — BROWN MICHAEL S2017-06-01: 2 option exercises at $466.02 close — STAHL NEIL2017-06-09: 1 option exercise at $475.79 close — GOLDSTEIN JOSEPH L2017-06-12: 1 option exercise at $476.23 close — BROWN MICHAEL S2017-06-14: 1 option exercise at $476.84 close — STAHL NEIL2017-06-15: 1 option exercise at $469.50 close — Terifay Robert J2017-06-20: 2 option exercises at $495.33 close — GOLDSTEIN JOSEPH L, BROWN MICHAEL S2017-06-21: 2 option exercises at $522.02 close — Aberman Michael S, STAHL NEIL2017-08-07: 1 option exercise at $470.10 close — Landry Robert E2017-08-10: 1 option exercise at $460.08 close — Terifay Robert J2017-08-16: 1 option exercise at $468.54 close — VAGELOS P ROY2017-08-22: 1 option exercise at $478.65 close — Landry Robert E2017-08-30: 1 option exercise at $487.12 close — Landry Robert E2017-09-01: 1 option exercise at $504.00 close — Landry Robert E2017-09-29: 1 option exercise at $447.12 close — BAKER CHARLES A2017-10-05: 1 option exercise at $463.40 close — BROWN MICHAEL S2017-12-11: 1 option exercise at $381.32 close — VAGELOS P ROY2017-12-12: 9 award or grants at $381.72 close — SCHLEIFER LEONARD S, YANCOPOULOS GEORGE, LAROSA JOSEPH J and 6 more2017-12-13: 2 option exercises at $386.67 close — SCHLEIFER LEONARD S, YANCOPOULOS GEORGE2018-01-02: 10 award or grants at $382.60 close — COLES N ANTHONY, BAKER CHARLES A, Zoghbi Huda Y and 7 more2018-01-02: 1 option exercise at $382.60 close — SING GEORGE L2018-01-16: 1 option exercise at $370.21 close — Fenimore Christopher R.2018-02-12: 1 award or grant at $342.67 close — McCourt Marion2018-03-14: 1 option exercise at $341.42 close — GOLDSTEIN JOSEPH L2018-03-19: 1 option exercise at $339.08 close — GOLDSTEIN JOSEPH L2018-05-23: 1 option exercise at $295.31 close — STAHL NEIL2018-06-20: 1 option exercise at $336.93 close — VAGELOS P ROY2018-07-05: 1 option exercise at $360.95 close — GOLDSTEIN JOSEPH L2018-07-06: 1 option exercise at $369.59 close — GOLDSTEIN JOSEPH L2018-07-09: 1 option exercise at $371.31 close — VAGELOS P ROY2018-08-02: 1 option exercise at $397.00 close — GOLDSTEIN JOSEPH L2018-08-20: 1 option exercise at $374.80 close — VAGELOS P ROY2018-08-22: 1 option exercise at $380.17 close — BROWN MICHAEL S2018-08-30: 1 option exercise at $408.51 close — Fenimore Christopher R.2018-09-24: 2 option exercises at $390.19 close — GOLDSTEIN JOSEPH L2018-09-27: 2 option exercises at $406.00 close — GOLDSTEIN JOSEPH L, BROWN MICHAEL S2018-09-28: 1 option exercise at $404.04 close — GOLDSTEIN JOSEPH L2018-12-12: 9 award or grants at $377.96 close — VAGELOS P ROY, YANCOPOULOS GEORGE, SCHLEIFER LEONARD S and 6 more2018-12-13: 4 option exercises at $378.51 close — YANCOPOULOS GEORGE, SCHLEIFER LEONARD S2018-12-19: 1 option exercise at $360.70 close — Fenimore Christopher R.2018-12-20: 1 option exercise at $356.23 close — Fenimore Christopher R.2019-01-02: 9 award or grants at $372.44 close — BROWN MICHAEL S, POON CHRISTINE A, SING GEORGE L and 6 more2019-01-10: 1 option exercise at $408.06 close — GOLDSTEIN JOSEPH L2019-01-18: 1 option exercise at $418.84 close — Fenimore Christopher R.2019-03-21: 1 option exercise at $402.59 close — SCHLEIFER LEONARD S2019-04-18: 1 option exercise at $333.34 close — Fenimore Christopher R.2019-05-13: 1 option exercise at $305.15 close — STAHL NEIL2019-05-24: 1 option exercise at $312.56 close — VAGELOS P ROY2019-11-12: 1 option exercise at $348.41 close — BROWN MICHAEL S2019-11-21: 1 option exercise at $350.78 close — GOLDSTEIN JOSEPH L2019-11-22: 2 option exercises at $360.66 close — VAGELOS P ROY, GOLDSTEIN JOSEPH L2019-11-25: 1 option exercise at $366.82 close — STAHL NEIL2019-11-27: 1 option exercise at $371.58 close — GOLDSTEIN JOSEPH L2019-12-11: 10 award or grants at $373.53 close — Fenimore Christopher R., VAGELOS P ROY, YANCOPOULOS GEORGE and 7 more2019-12-12: 6 option exercises at $372.16 close — Fenimore Christopher R., VAGELOS P ROY, YANCOPOULOS GEORGE and 1 more2019-12-13: 1 option exercise at $376.42 close — BROWN MICHAEL S2019-12-20: 1 option exercise at $375.62 close — Fenimore Christopher R.2020-01-02: 9 award or grants at $373.35 close — Tessier-Lavigne Marc, POON CHRISTINE A, Zoghbi Huda Y and 6 more2020-01-02: 1 option exercise at $373.35 close — SING GEORGE L2020-01-24: 1 option exercise at $345.28 close — Fenimore Christopher R.2020-02-12: 2 option exercises at $406.30 close — Landry Robert E, STAHL NEIL2020-02-13: 2 option exercises at $398.81 close — Tessier-Lavigne Marc2020-02-24: 2 option exercises at $425.38 close — Landry Robert E, BROWN MICHAEL S2020-02-25: 2 option exercises at $442.35 close — Van Plew Daniel P, Landry Robert E2020-02-26: 2 option exercises at $457.92 close — STAHL NEIL, SING GEORGE L2020-03-09: 3 option exercises at $474.44 close — YANCOPOULOS GEORGE, GOLDSTEIN JOSEPH L2020-04-01: 7 option exercises at $496.65 close — Landry Robert E, LAROSA JOSEPH J, Fenimore Christopher R.2020-04-02: 1 option exercise at $498.75 close — Landry Robert E2020-04-06: 1 option exercise at $504.27 close — Landry Robert E2020-04-09: 1 option exercise at $512.96 close — Landry Robert E2020-04-13: 1 option exercise at $517.02 close — STAHL NEIL2020-04-14: 2 option exercises at $524.84 close — LAROSA JOSEPH J, Landry Robert E2020-04-16: 2 option exercises at $539.93 close — Landry Robert E, LAROSA JOSEPH J2020-04-17: 3 option exercises at $568.79 close — Landry Robert E, LAROSA JOSEPH J2020-05-06: 12 option exercises at $553.50 close — Van Plew Daniel P, Tessier-Lavigne Marc, RYAN ARTHUR F and 1 more2020-05-07: 1 option exercise at $559.83 close — Zoghbi Huda Y2020-05-08: 1 option exercise at $563.40 close — STAHL NEIL2020-05-11: 2 option exercises at $574.11 close — SCHLEIFER LEONARD S2020-05-13: 1 option exercise at $577.12 close — SING GEORGE L2020-05-14: 1 option exercise at $570.86 close — LAROSA JOSEPH J2020-05-20: 5 option exercises at $576.89 close — VAGELOS P ROY2020-06-05: 1 option exercise at $597.00 close — Bassler Bonnie L2020-06-08: 9 option exercises at $604.04 close — Landry Robert E, GOLDSTEIN JOSEPH L2020-06-10: 2 option exercises at $606.59 close — Zoghbi Huda Y, Landry Robert E2020-06-11: 1 option exercise at $596.16 close — Zoghbi Huda Y2020-06-15: 2 option exercises at $590.57 close — Fenimore Christopher R.2020-06-19: 1 option exercise at $643.92 close — Bassler Bonnie L2020-06-22: 1 option exercise at $628.48 close — Landry Robert E2020-07-01: 1 option exercise at $609.17 close — BROWN MICHAEL S2020-07-07: 4 option exercises at $640.88 close — Landry Robert E, SING GEORGE L, Zoghbi Huda Y2020-07-09: 1 option exercise at $640.63 close — Landry Robert E2020-07-13: 1 option exercise at $615.88 close — MURPHY ANDREW J2020-07-20: 4 option exercises at $658.21 close — Fenimore Christopher R., Landry Robert E2020-08-20: 3 option exercises at $616.89 close — McCourt Marion, SING GEORGE L, Van Plew Daniel P2020-08-21: 2 option exercises at $605.49 close — SING GEORGE L2020-08-24: 1 option exercise at $594.77 close — SING GEORGE L2020-08-25: 1 option exercise at $610.50 close — SING GEORGE L2020-08-27: 2 option exercises at $614.97 close — LAROSA JOSEPH J2020-08-28: 2 option exercises at $602.61 close — POON CHRISTINE A2020-09-21: 3 option exercises at $555.70 close — GOLDSTEIN JOSEPH L2020-09-22: 2 option exercises at $571.51 close — BROWN MICHAEL S2020-10-05: 2 option exercises at $605.08 close — GOLDSTEIN JOSEPH L, McCourt Marion2020-10-22: 2 option exercises at $575.73 close — MURPHY ANDREW J2020-11-13: 1 option exercise at $566.43 close — COLES N ANTHONY2020-11-16: 1 option exercise at $559.29 close — MURPHY ANDREW J2020-12-09: 8 award or grants at $488.64 close — MURPHY ANDREW J, VAGELOS P ROY, Van Plew Daniel P and 5 more2020-12-30: 2 option exercises at $478.30 close — YANCOPOULOS GEORGE2021-01-04: 9 award or grants at $482.86 close — BROWN MICHAEL S, SING GEORGE L, Zoghbi Huda Y and 6 more2021-01-25: 1 option exercise at $548.20 close — BROWN MICHAEL S2021-02-23: 2 option exercises at $468.03 close — VAGELOS P ROY2021-05-07: 1 option exercise at $496.75 close — McCourt Marion2021-05-14: 2 option exercises at $516.62 close — STAHL NEIL2021-06-07: 2 option exercises at $514.99 close — GOLDSTEIN JOSEPH L, McCourt Marion2021-06-14: 1 option exercise at $528.75 close — BROWN MICHAEL S2021-06-25: 1 option exercise at $550.55 close — BROWN MICHAEL S2021-07-01: 2 option exercises at $574.62 close — McCourt Marion, Bassler Bonnie L2021-07-02: 1 option exercise at $583.64 close — LAROSA JOSEPH J2021-08-02: 1 option exercise at $577.13 close — McCourt Marion2021-08-05: 1 option exercise at $602.47 close — Bassler Bonnie L2021-08-06: 3 option exercises at $610.86 close — Landry Robert E, SCHLEIFER LEONARD S2021-08-09: 2 option exercises at $613.94 close — Landry Robert E, Van Plew Daniel P2021-08-13: 1 option exercise at $624.79 close — COLES N ANTHONY2021-08-16: 1 option exercise at $628.60 close — Bassler Bonnie L2021-08-17: 1 option exercise at $647.44 close — COLES N ANTHONY2021-08-18: 1 option exercise at $635.57 close — COLES N ANTHONY2021-08-20: 2 option exercises at $663.27 close — LAROSA JOSEPH J, Fenimore Christopher R.2021-08-25: 1 option exercise at $669.18 close — VAGELOS P ROY2021-08-27: 1 option exercise at $663.29 close — POON CHRISTINE A2021-08-31: 1 option exercise at $673.40 close — Landry Robert E2021-09-01: 1 option exercise at $680.96 close — McCourt Marion2021-09-10: 1 option exercise at $650.49 close — GOLDSTEIN JOSEPH L2021-09-13: 7 option exercises at $639.52 close — BROWN MICHAEL S, Zoghbi Huda Y, Tessier-Lavigne Marc2021-09-14: 1 option exercise at $645.15 close — Zoghbi Huda Y2021-09-15: 2 option exercises at $652.00 close — COLES N ANTHONY2021-10-01: 1 option exercise at $570.79 close — McCourt Marion2021-11-01: 1 option exercise at $639.15 close — McCourt Marion2021-11-15: 2 option exercises at $647.73 close — MURPHY ANDREW J, Van Plew Daniel P2021-11-16: 1 option exercise at $642.75 close — Landry Robert E2021-11-19: 2 option exercises at $652.68 close — SCHLEIFER LEONARD S2021-12-01: 1 option exercise at $630.59 close — McCourt Marion2021-12-03: 1 option exercise at $635.16 close — STAHL NEIL2021-12-08: 8 award or grants at $654.04 close — MURPHY ANDREW J, Landry Robert E, Van Plew Daniel P and 5 more2021-12-09: 4 option exercises at $665.72 close — MURPHY ANDREW J, Tessier-Lavigne Marc, Landry Robert E and 1 more2021-12-10: 1 option exercise at $669.52 close — Landry Robert E2021-12-22: 2 option exercises at $617.48 close — YANCOPOULOS GEORGE2022-01-03: 9 award or grants at $627.10 close — POON CHRISTINE A, Zoghbi Huda Y, Tessier-Lavigne Marc and 6 more2022-01-03: 1 option exercise at $627.10 close — McCourt Marion2022-02-01: 1 option exercise at $613.36 close — McCourt Marion2022-02-14: 1 option exercise at $623.53 close — MURPHY ANDREW J2022-02-22: 1 option exercise at $602.89 close — Van Plew Daniel P2022-03-01: 1 option exercise at $607.03 close — McCourt Marion2022-03-14: 1 option exercise at $656.41 close — VAGELOS P ROY2022-03-16: 2 option exercises at $677.98 close — Zoghbi Huda Y, Tessier-Lavigne Marc2022-03-17: 2 option exercises at $685.23 close — Landry Robert E, Tessier-Lavigne Marc2022-03-21: 2 option exercises at $693.20 close — Landry Robert E, Tessier-Lavigne Marc2022-03-28: 5 option exercises at $693.40 close — Landry Robert E2022-03-29: 1 option exercise at $698.43 close — BROWN MICHAEL S2022-03-30: 3 option exercises at $692.38 close — GOLDSTEIN JOSEPH L, Bassler Bonnie L, BROWN MICHAEL S2022-03-31: 3 option exercises at $698.42 close — Fenimore Christopher R., Landry Robert E2022-04-01: 1 option exercise at $694.83 close — McCourt Marion2022-04-07: 2 option exercises at $721.80 close — Landry Robert E, Bassler Bonnie L2022-04-08: 4 option exercises at $738.84 close — Landry Robert E, Fenimore Christopher R.2022-05-02: 1 option exercise at $652.02 close — McCourt Marion2022-05-16: 1 option exercise at $655.01 close — MURPHY ANDREW J2022-06-01: 1 option exercise at $658.92 close — McCourt Marion2022-07-01: 1 option exercise at $595.40 close — McCourt Marion2022-08-01: 1 option exercise at $576.68 close — McCourt Marion2022-08-04: 4 option exercises at $614.96 close — RYAN ARTHUR F, STAHL NEIL2022-08-09: 1 option exercise at $622.15 close — POON CHRISTINE A2022-08-15: 1 option exercise at $643.29 close — MURPHY ANDREW J2022-09-01: 1 option exercise at $600.63 close — McCourt Marion2022-09-06: 2 option exercises at $573.97 close — COLES N ANTHONY2022-09-08: 2 option exercises at $708.85 close — Bassler Bonnie L2022-09-09: 3 option exercises at $724.32 close — Van Plew Daniel P, Bassler Bonnie L, LAROSA JOSEPH J2022-09-29: 1 option exercise at $691.82 close — Tessier-Lavigne Marc2022-09-30: 1 option exercise at $688.87 close — Tessier-Lavigne Marc2022-10-03: 1 award or grant at $735.13 close — Thompson Craig B.2022-10-03: 3 option exercises at $735.13 close — McCourt Marion, Tessier-Lavigne Marc2022-10-14: 1 option exercise at $736.06 close — Landry Robert E2022-10-31: 1 option exercise at $748.75 close — Landry Robert E2022-11-01: 1 option exercise at $759.91 close — McCourt Marion2022-11-04: 2 option exercises at $740.21 close — Van Plew Daniel P, McCourt Marion2022-11-08: 2 option exercises at $751.95 close — BROWN MICHAEL S2022-11-14: 1 option exercise at $742.01 close — MURPHY ANDREW J2022-11-22: 1 option exercise at $749.23 close — Van Plew Daniel P2022-12-01: 2 option exercises at $761.24 close — McCourt Marion, Landry Robert E2022-12-08: 2 option exercises at $765.42 close — Bassler Bonnie L, Landry Robert E2022-12-16: 8 award or grants at $723.17 close — VAGELOS P ROY, Van Plew Daniel P, STAHL NEIL and 5 more2022-12-28: 2 option exercises at $713.03 close — COLES N ANTHONY2023-01-03: 11 award or grants at $720.47 close — RYAN ARTHUR F, Bassler Bonnie L, BROWN MICHAEL S and 7 more2023-01-03: 1 option exercise at $720.47 close — McCourt Marion2023-01-06: 1 option exercise at $737.15 close — BROWN MICHAEL S2023-01-27: 1 option exercise at $742.83 close — BROWN MICHAEL S2023-02-01: 1 option exercise at $758.00 close — McCourt Marion2023-02-03: 3 option exercises at $783.13 close — Fenimore Christopher R., Bassler Bonnie L, Landry Robert E2023-02-06: 2 option exercises at $780.86 close — GOLDSTEIN JOSEPH L, BROWN MICHAEL S2023-02-07: 1 option exercise at $769.94 close — McCourt Marion2023-02-22: 1 option exercise at $748.08 close — VAGELOS P ROY2023-03-01: 1 option exercise at $770.44 close — McCourt Marion2023-03-23: 1 option exercise at $802.16 close — LAROSA JOSEPH J2023-03-24: 1 option exercise at $820.00 close — Bassler Bonnie L2023-03-27: 2 option exercises at $820.41 close — Landry Robert E2023-04-03: 1 option exercise at $826.19 close — McCourt Marion2023-04-21: 1 option exercise at $800.73 close — BROWN MICHAEL S2023-08-10: 1 option exercise at $793.01 close — Bassler Bonnie L2023-08-21: 2 option exercises at $844.37 close — STAHL NEIL, Bassler Bonnie L2023-08-23: 3 option exercises at $840.81 close — Fenimore Christopher R., POON CHRISTINE A, Van Plew Daniel P2023-09-08: 2 award or grants at $830.69 close — Schenkein David P, Guarini Kathryn2023-10-02: 1 option exercise at $818.03 close — McCourt Marion2023-10-13: 1 option exercise at $839.63 close — Zoghbi Huda Y2023-11-01: 1 option exercise at $791.27 close — McCourt Marion2023-11-13: 1 option exercise at $796.70 close — MURPHY ANDREW J2023-12-04: 1 option exercise at $823.32 close — MURPHY ANDREW J2023-12-08: 6 award or grants at $840.14 close — Van Plew Daniel P, STAHL NEIL, MURPHY ANDREW J and 3 more2023-12-13: 2 option exercises at $876.12 close — Landry Robert E, Bassler Bonnie L2023-12-27: 2 option exercises at $874.37 close — BROWN MICHAEL S, Landry Robert E2023-12-28: 1 option exercise at $881.70 close — Landry Robert E2024-01-02: 11 award or grants at $905.00 close — Schenkein David P, Guarini Kathryn, Thompson Craig B. and 8 more2024-01-02: 2 option exercises at $905.00 close — Landry Robert E, Zoghbi Huda Y2024-01-03: 5 option exercises at $917.56 close — Fenimore Christopher R., LAROSA JOSEPH J, Landry Robert E and 1 more2024-01-04: 1 option exercise at $912.17 close — Landry Robert E2024-01-12: 1 option exercise at $933.20 close — Landry Robert E2024-01-17: 1 option exercise at $929.13 close — Landry Robert E2024-01-23: 4 option exercises at $954.58 close — GOLDSTEIN JOSEPH L, Fenimore Christopher R., Landry Robert E2024-01-24: 1 option exercise at $948.24 close — Landry Robert E2024-01-30: 1 option exercise at $959.73 close — Bassler Bonnie L2024-01-31: 1 option exercise at $942.78 close — Landry Robert E2024-02-02: 2 option exercises at $945.18 close — STAHL NEIL, Landry Robert E2024-02-08: 1 option exercise at $946.43 close — SING GEORGE L2024-02-09: 3 option exercises at $953.42 close — Van Plew Daniel P, SING GEORGE L2024-02-15: 1 option exercise at $954.73 close — YANCOPOULOS GEORGE2024-02-22: 1 option exercise at $964.89 close — SING GEORGE L2024-02-23: 1 option exercise at $981.20 close — SING GEORGE L2024-02-26: 2 option exercises at $989.28 close — SING GEORGE L, Bassler Bonnie L2024-03-13: 1 option exercise at $965.47 close — MURPHY ANDREW J2024-05-03: 1 option exercise at $957.00 close — SING GEORGE L2024-05-13: 1 option exercise at $976.96 close — SCHLEIFER LEONARD S2024-05-28: 1 option exercise at $973.16 close — BROWN MICHAEL S2024-06-03: 1 option exercise at $989.48 close — McCourt Marion2024-06-05: 1 option exercise at $1,005.87 close — Bassler Bonnie L2024-06-14: 1 option exercise at $1,036.52 close — BROWN MICHAEL S2024-06-24: 2 option exercises at $1,063.89 close — Bassler Bonnie L, LAROSA JOSEPH J2024-07-01: 1 option exercise at $1,057.02 close — McCourt Marion2024-08-01: 1 option exercise at $1,093.14 close — McCourt Marion2024-08-02: 2 option exercises at $1,082.19 close — STAHL NEIL, Bassler Bonnie L2024-08-07: 1 option exercise at $1,067.80 close — Pitofsky Jason2024-08-13: 1 option exercise at $1,158.33 close — MURPHY ANDREW J2024-08-15: 2 option exercises at $1,175.33 close — Bassler Bonnie L, POON CHRISTINE A2024-09-03: 1 option exercise at $1,168.81 close — McCourt Marion2024-10-01: 1 option exercise at $1,046.91 close — McCourt Marion2024-11-01: 1 option exercise at $843.60 close — McCourt Marion2024-12-06: 6 award or grants at $778.00 close — Pitofsky Jason, Fenimore Christopher R., Van Plew Daniel P and 3 more2024-12-31: 1 option exercise at $712.33 close — SING GEORGE L2025-01-02: 11 award or grants at $715.19 close — Schenkein David P, Thompson Craig B., COLES N ANTHONY and 8 more2025-10-29: 2 option exercises at $652.91 close — POON CHRISTINE A, MURPHY ANDREW J2025-10-30: 1 option exercise at $654.04 close — POON CHRISTINE A2025-11-20: 2 option exercises at $737.00 close — LAROSA JOSEPH J, Bassler Bonnie L2025-12-05: 6 award or grants at $718.36 close — Pitofsky Jason, Van Plew Daniel P, MURPHY ANDREW J and 3 more2025-12-09: 2 option exercises at $692.58 close — YANCOPOULOS GEORGE, SCHLEIFER LEONARD S2025-12-30: 1 option exercise at $773.94 close — SING GEORGE L2026-01-02: 11 award or grants at $776.31 close — Zoghbi Huda Y, Thompson Craig B., SING GEORGE L and 8 more2026-01-07: 1 option exercise at $812.27 close — Bassler Bonnie L2026-02-09: 1 option exercise at $780.28 close — Pitofsky Jason2026-02-19: 1 option exercise at $782.38 close — Zoghbi Huda Y2026-08-10: 2 option exercises at $808.05 close — Guarini Kathryn, Zoghbi Huda Y2026-08-18: 1 option exercise at $810.24 close — Fenimore Christopher R.2026-08-19: 1 option exercise at $840.84 close — LAROSA JOSEPH J2026-09-02: 1 option exercise at $852.03 close — Guarini Kathryn

Logarithmic scale. Both lines share the same starting value for the selected range.

Markers: each transaction type positioned at that session's split-adjusted close. Tooltips retain the reported transaction price when available.

Transaction dateReporting ownerFormSecurityTransactionSharesPricePrice that dayFiling
2026-09-02Guarini Kathryn
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−400
1,158 owned after		$719.37
exercise price		$852.032026-09-03
2026-08-19LAROSA JOSEPH J
Officer (EVP General Counsel and Secret)		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−12,282
12,283 owned after		$381.92
exercise price		$840.842026-08-21
2026-08-18Fenimore Christopher R.
Officer (EVP Finance CFO)		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−6,283
6,000 owned after		$381.92
exercise price		$810.242026-08-20
2026-08-10Guarini Kathryn
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−400
1,558 owned after		$719.37
exercise price		$808.052026-08-12
2026-08-10Zoghbi Huda Y
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−800
0 owned after		$376.69
exercise price		$808.052026-08-12
2026-02-19Zoghbi Huda Y
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−1,638
800 owned after		$376.69
exercise price		$782.382026-02-23
2026-02-09Pitofsky Jason
Officer (SVP Controller)		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−1,000
905 owned after		$492.00
exercise price		$780.282026-02-11
2026-01-07Bassler Bonnie L
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3−1,500
2,861 owned after		$374.12
exercise price		$812.272026-01-08
2026-01-02Zoghbi Huda Y
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02Thompson Craig B.
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02SING GEORGE L
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02Guarini Kathryn
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02Schenkein David P
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02GOLDSTEIN JOSEPH L
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02RYAN ARTHUR F
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02COLES N ANTHONY
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02BROWN MICHAEL S
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02Bassler Bonnie L
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06
2026-01-02POON CHRISTINE A
Director		4Non-Qualified Stock Option (right to buy)
Derivative · Direct		A Grant, award or other acquisition pursuant to Rule 16b-3(d)+1,962
1,962 owned after		$772.76
exercise price		$776.312026-01-06

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