TREVENA, INC. Clinical Trials
Studies registered on ClinicalTrials.gov (U.S. National Library of Medicine) with the company as lead sponsor or collaborator, newest start first. Values are as registered.
- 2019-11-11: Study NCT04201080; Company role Lead sponsor; Phase Phase 1; Status Terminated.
- 2016-05: Study NCT02820324; Company role Lead sponsor; Phase Phase 3; Status Completed.
- 2016-05: Study NCT02815709; Company role Lead sponsor; Phase Phase 3; Status Completed.
- 2015-12: Study NCT02656875; Company role Lead sponsor; Phase Phase 3; Status Completed.
| Start date | Study | Company role | Phase | Status | Conditions | Enrollment | Completion date |
|---|---|---|---|---|---|---|---|
| 2019-11-11 | NCT04201080 A Trial to Evaluate the Efficacy, Safety and Tolerability of Subcutaneous TRV250 | Lead sponsor | Phase 1 | Terminated | Migraines | 9 | 2020-08-10 |
| 2016-05 | NCT02820324 Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Abdominoplasty | Lead sponsor | Phase 3 | Completed Results posted | Acute Pain | 407 | 2017-01 |
| 2016-05 | NCT02815709 Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Bunionectomy | Lead sponsor | Phase 3 | Completed Results posted | Acute Pain | 418 | 2017-01 |
| 2015-12 | NCT02656875 A Open-label Study to Evaluate the Safety of TRV130 in Patients With Acute Pain | Lead sponsor | Phase 3 | Completed Results posted | Acute Pain | 768 | 2017-08 |
| 2015-10-20 | NCT02520297 A Pilot Study of TRV130 for the Treatment of Fracture Pain | Lead sponsor | Phase 2 | Terminated Results posted | Pain | 1 | 2015-10-23 |
| 2015-02 | NCT02411500 A Pharmacokinetic, Safety and Tolerability Study in Healthy Adult Males | Lead sponsor | Phase 1 | Completed | Healthy | 18 | 2015-03 |
| 2014-12 | NCT02344303 Study of the Effects of TRV130, at Therapeutic and Supra Therapeutic Doses, on QTc Intervals | Lead sponsor | Phase 1 | Completed | Healthy | 63 | 2015-10 |
| 2014-12 | NCT02335294 A Study of TRV130 for the Treatment of Pain After Abdominoplasty | Lead sponsor | Phase 2 | Completed Results posted | Pain | 200 | 2015-08 |
| 2014-07 | NCT02211625 A Safety, Tolerability, PD and PK Study in Healthy Adults | Lead sponsor | Phase 1 | Completed | Healthy | 75 | 2014-10 |
| 2014-06 | NCT02169934 A Study to Investigate the Metabolism and Excretion of [14C]-TRV130 in Healthy Male Subjects | Lead sponsor | Phase 1 | Completed | Healthy | 6 | 2015-05 |
| 2014-04 | NCT02100748 A Study of TRV130 for the Treatment of Pain After Bunionectomy | Lead sponsor | Phase 2 | Completed Results posted | Acute Pain | 333 | 2014-10 |
| 2013-12 | NCT01966601 A Study to Explore the Efficacy of TRV027 in Patients Hospitalized for Acute Decompensated Heart Failure | Lead sponsor | Phase 2 | Completed | Acute Decompensated Heart Failure | 620 | 2016-09 |
| 2013-07 | NCT02083315 Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects | Lead sponsor | Phase 1 | Completed | Pain, Acute | 30 | 2013-08 |
| 2012-01 | NCT01514578 Single Ascending Dose Study of Intravenous TRV130A in Healthy Adult Males | Lead sponsor | Phase 1 | Completed | Healthy | 74 | 2012-07 |
| 2011-08 | NCT01444872 Study to Evaluate TRV120027 on Renal Pharmacodynamics in Patients With Heart Failure and Renal Dysfunction | Lead sponsor | Phase 1 | Completed | Heart Failure; Kidney Disease | 17 | 2012-06 |
| 2010-12 | NCT01187836 Study to Evaluate the Effects of TRV120027 in Patients With Heart Failure | Lead sponsor | Phase 1, Phase 2 | Completed | Heart Failure | 33 | 2012-03 |