TETRAPHASE PHARMACEUTICALS INC Clinical Trials
Studies registered on ClinicalTrials.gov (U.S. National Library of Medicine) with the company as lead sponsor or collaborator, newest start first. Values are as registered.
- 2025-05-22: Study NCT06794541; Company role Lead sponsor; Phase Phase 2; Status Recruiting.
- 2018-12-20: Study NCT03696550; Company role Lead sponsor; Phase Phase 1; Status Completed.
- 2018-11-26: Study NCT03691584; Company role Lead sponsor; Phase Phase 1; Status Completed.
- 2018-03-20: Study NCT03450187; Company role Lead sponsor; Phase Phase 1; Status Completed.
| Start date | Study | Company role | Phase | Status | Conditions | Enrollment | Completion date |
|---|---|---|---|---|---|---|---|
| 2025-05-22 | NCT06794541 A Study to Evaluate the Safety and Tolerability of Eravacycline in Pediatric Patients Aged 8 to 17 With Complicated Intra-abdominal Infections (cIAI) | Lead sponsor | Phase 2 | Recruiting | Complicated Intra-abdominal Infections (cIAI) | 35 | 2029-03-19 |
| 2018-12-20 | NCT03696550 A Safety and PK Study of IV Eravacycline | Lead sponsor | Phase 1 | Completed | Bacterial Infections | 19 | 2021-03-19 |
| 2018-11-26 | NCT03691584 Phase 1, Safety and Bronchopulmonary PK Study in Healthy Volunteers | Lead sponsor | Phase 1 | Completed | Healthy Subjects | 8 | 2019-12-18 |
| 2018-03-20 | NCT03450187 A Phase 1 TP-271 Oral PK Multiple Ascending Dose Study | Lead sponsor | Phase 1 | Completed | Bacterial Infections | 40 | 2019-03-31 |
| 2017-08-16 | NCT03234738 A Phase 1 Safety and PK Study of IV TP-271 | Lead sponsor | Phase 1 | Completed | Bacterial Infections | 40 | 2018-01-02 |
| 2017-03-02 | NCT03024034 A Phase 1 TP-271 Oral PK Single Ascending Dose Study | Lead sponsor | Phase 1 | Completed | Bacterial Infections | 56 | 2018-06-04 |
| 2017-01 | NCT03032510 Efficacy and Safety Study of Eravacycline Compared With Ertapenem in Participants With Complicated Urinary Tract Infections | Lead sponsor | Phase 3 | Completed Results posted | Complicated Urinary Tract Infections | 1,205 | 2018-01 |
| 2016-10-13 | NCT02784704 Efficacy and Safety Study of Eravacycline Compared With Meropenem in Complicated Intra-abdominal Infections | Lead sponsor | Phase 3 | Completed Results posted | Complicated Intra-abdominal Infections; Complicated Appendicitis | 500 | 2017-05-19 |
| 2015-12-18 | NCT02724085 A Phase 1 Study to Assess the Safety, Tolerability and PK of IV TP-271 | Lead sponsor | Phase 1 | Completed | Pneumonia | 57 | 2016-12-12 |
| 2014-10-06 | NCT01978938 Efficacy and Safety Study of Eravacycline Compared With Levofloxacin in Complicated Urinary Tract Infections | Lead sponsor | Phase 3 | Completed Results posted | cUTI | 908 | 2015-08-21 |
| 2013-12 | NCT02135276 A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With End Stage Renal Disease and Healthy Subjects | Lead sponsor | Phase 1 | Completed | End Stage Renal Disease | 12 | 2014-05 |
| 2013-10 | NCT02135302 A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With Impaired Hepatic Function and Healthy Subjects | Lead sponsor | Phase 1 | Completed | Impaired Hepatic Function | 24 | 2014-03 |
| 2013-08 | NCT01844856 Efficacy and Safety Study of Eravacycline Compared With Ertapenem in Complicated Intra-abdominal Infections | Lead sponsor | Phase 3 | Completed Results posted | Complicated Intra-abdominal Infections | 541 | 2014-08 |
| 2013-03 | NCT01941446 A Thorough QT/QTc Study to Evaluate the Effects of an Intravenous Infusion of Eravacycline (TP-434) on Cardiac Repolarization | Lead sponsor | Phase 1 | Completed | Normal Healthy Subjects | 54 | 2013-07 |
| 2012-11 | NCT01989949 Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women | Lead sponsor | Phase 1 | Completed | Normal Drug Tolerance | 20 | 2013-04 |
| 2011-01 | NCT01265784 Study to Compare TP-434 and Ertapenem in Community-acquired Complicated Intra-abdominal Infections | Lead sponsor | Phase 2 | Completed Results posted | Complicated Intra-abdominal Infection | 143 | 2012-05 |