PRINCIPIA BIOPHARMA INC. Active Patents
51 granted patents the USPTO still lists as patented, newest filing first, as the USPTO Open Data Portal records them; the company is the first-named applicant. The application number opens the full record at Patent Center.
- 2024-03-22: Application 18613641; Invention Therapeutic Tyrosine Kinase Inhibitors for Relapsing Multiple Sclerosis (RMS); Applicant Principia Biopharma Inc.; Status Patented Case.
- 2023-12-01: Application 18526225; Invention Modified Release Formulations of 2-[3-[4-Amino-3-(2-Fluoro-4-Phenoxy-Phenyl) Pyrazolo[3,4-D] Pyrimidin-1-YL]Piperidine-1-Carbonyl]-4-Methyl -4-[4-(Oxetan-3-YL)Piperazin-1-YL]Pent-2-Enenitrile; Applicant Principia Biopharma Inc.; Status Patented Case.
- 2023-10-17: Application 18380962; Invention Immunoproteasome Inhibitors; Applicant Principia Biopharma Inc.; Status Patented Case.
- 2023-10-06: Application 18482278; Invention Crystalline Forms of 2-[3-[4-Amino-3-(2-Fluoro-4-Phenoxy-Phenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-1- YL]Piperidine-1-Carbonyl]-4-Methyl-4-[4-(Oxetan-3-YL)Piperazin-1-YL]Pent-2- Enenitrile; Applicant Principia Biopharma Inc.; Status Patented Case.
| Filed | Application | Invention | Applicant | Status | Granted | Patent | Published as | Inventor name | Inventor country | Examiner |
|---|---|---|---|---|---|---|---|---|---|---|
| 2024-03-22 | 18613641 | Therapeutic Tyrosine Kinase Inhibitors for Relapsing Multiple Sclerosis (RMS) | Principia Biopharma Inc. | Patented Case | 2026-05-26 | 12636280 | US20240366585A1 | Meehyung Cho Timothy J. Turner Erik Wallstroem | United States United States United States | YOO, SUN JAE |
| 2023-12-01 | 18526225 | Modified Release Formulations of 2-[3-[4-Amino-3-(2-Fluoro-4-Phenoxy-Phenyl) Pyrazolo[3,4-D] Pyrimidin-1-YL]Piperidine-1-Carbonyl]-4-Methyl -4-[4-(Oxetan-3-YL)Piperazin-1-YL]Pent-2-Enenitrile | Principia Biopharma Inc. | Patented Case | 2025-06-24 | 12336999 | US20240207275A1 | Abu J. Ferdous Mohammad R. Masjedizadeh Wu Lin | United States United States United Kingdom | VU, JAKE MINH |
| 2023-10-17 | 18380962 | Immunoproteasome Inhibitors | Principia Biopharma Inc. | Patented Case | 2025-05-27 | 12312370 | US20240199655A1 | Yan Lou Timothy Duncan Owens Kenneth Albert Brameld David Michael Goldstein | United States United States United States United States | SHAMEEM, GOLAM M |
| 2023-10-06 | 18482278 | Crystalline Forms of 2-[3-[4-Amino-3-(2-Fluoro-4-Phenoxy-Phenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-1- YL]Piperidine-1-Carbonyl]-4-Methyl-4-[4-(Oxetan-3-YL)Piperazin-1-YL]Pent-2- Enenitrile | Principia Biopharma Inc. | Patented Case | 2025-09-09 | 12410176 | US20240182484A1 | Pasit Phiasivongsa Kolbot By Jean Baum | United States United States United States | SOLOLA, TAOFIQ A |
| 2023-06-30 | 18217002 | Quinolone Derivatives as Fibroblast Growth Factor Receptor Inhibitors | Principia Biopharma Inc. | Patented Case | 2024-12-10 | 12162882 | US20240092777A1 | Erik Verner Kenneth Albert Brameld | United States United States | SZNAIDMAN, MARCOS L |
| 2023-06-20 | 18268577 | 4-AMINO-3-(4-PHENOXYPHENYL)-1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES AND SALTS THEREOF | Principia Biopharma Inc. | Patented Case | 2026-05-12 | 12624030 | US20240051955A1 | Catherine Arabeyre Patricia Moliner Sabine Boisnard Damien Sallaberry Serge Perard Sebastien Roy | France France France France France France | RAHMANI, NILOOFAR |
| 2023-05-16 | 18197979 | PROCESS FOR PREPARING AN AMORPHOUS FORM OF 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXYPHENYL)PYRAZOLO[3,4-d]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4-[4-(OXETAN-3-YL)PIPERAZIN-1-YL]PENT-2-ENENITRILE | Principia Biopharma Inc. | Patented Case | 2026-07-07 | 12673953 | US20230399330A1 | Kolbot By Katherine Chu Mohammad R. Masjedizadeh Pasit Phiasivongsa Jiang Zhu | United States United States United States United States United States | WILLIS, DOUGLAS M |
| 2023-04-25 | 18306649 | CRYSTALLINE FORMS OF 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXYPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4,4-DIMETHYLPENT-2-ENENITRILE | Principia Biopharma Inc. | Patented Case | 2025-04-22 | 12281120 | US20240190882A1 | Kolbot By Mohammad R. Masjedizadeh Pasit Phiasivongsa Jiang Zhu | United States United States United States United States | WILLIS, DOUGLAS M |
| 2022-09-16 | 17946585 | Methods for Treating Immune Thrombocytopenia by Administering (R)-2-[3-[4-Amino-3-(2-Fluoro-4-Phenoxy- Phenyl) Pyrazolo[3,4-D]Pyrimidin-1-YL]Piperidine-1-Carbonyl]-4-Methyl-4-[4-(Oxetan-3-YL)Piperazin-1-YL]Pent-2-Enenitrile | Principia Biopharma Inc. | Patented Case | 2024-12-31 | 12178818 | US20230124267A1 | Steven Gourlay Ann Neale Philip Nunn Claire Langrish Olga Bandman Dolca Thomas | Australia United States United States United States United States United States | PIHONAK, SARAH |
| 2021-11-16 | 17527514 | Immunoproteasome Inhibitors | Principia Biopharma Inc. | Patented Case | 2023-11-28 | 11827656 | US20220073538A1 | Yan Lou Timothy Duncan Owens Kenneth Albert Brameld David Michael Goldstein | United States United States United States United States | SHAMEEM, GOLAM M |
| 2021-01-22 | 17155726 | PROCESSES FOR PREPARING AN FGFR INHIBITOR | Principia Biopharma, Inc. | Patented Case | 2025-04-22 | 12281110 | US20210147417A1 | Jiang ZHU Mohammad MASJEDIZADEH | United States United States | KENYON, JOHN S |
| 2021-01-21 | 17154452 | CRYSTALLINE FORMS OF 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4-[4-(OXETAN-3-YL)PIPERAZIN-1-YL]PENT-2-ENENITRILE | Principia Biopharma Inc. | Patented Case | 2023-11-14 | 11814390 | US20210221818A1 | Pasit Phiasivongsa Kolbot By Jean Baum | United States United States United States | SOLOLA, TAOFIQ A |
| 2021-01-07 | 17143384 | TOPICAL PHARMACEUTICAL COMPOSITIONS COMPRISING 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4,4-DIMETHYLPENT-2-ENENITRILE | Principia Biopharma Inc. | Patented Case | 2023-02-21 | 11583533 | US20210205313A1 | Katherine CHU Jyoti WADHWA Jason CARBOL Pasit PHIASIVONGSA Claire LANGRISH Dolca THOMAS | United States United States United States United States United States United States | MERCIER, MELISSA S |
| 2021-01-07 | 17143355 | CRYSTALLINE FORMS OF 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXYPHENYL)-1H-PYRAZOLO[3,4-d]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4,4-DIMETHYLPENT-2-ENENITRILE | Principia Biopharma Inc. | Patented Case | 2023-06-06 | 11667641 | US20210206772A1 | Pasit Phiasivongsa Jiang Zhu Kolbot By Mohammad Reza Masjedizadeh | United States United States United States United States | WILLIS, DOUGLAS M |
| 2020-12-17 | 17125384 | SOLID FORMS OF 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXYPHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4-[4-(OXETAN-3-YL)PIPERAZIN-1-YL]PENT-2-ENENITRILE | Principia Biopharma Inc. | Patented Case | 2023-07-25 | 11708370 | US20210198264A1 | Pasit Phiasivongsa Katherine Chu Jiang Zhu Kolbot By Mohammad Reza Masjedizadeh | United States United States United States United States United States | WILLIS, DOUGLAS M |
| 2020-10-28 | 17082747 | MODIFIED RELEASE FORMULATIONS OF 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4-[4-(OXETAN-3-YL)PIPERAZIN-1-YL]PENT-2-ENENITRILE | Principia Biopharma Inc. | Patented Case | 2024-01-16 | 11872229 | US20210113567A1 | Abu J. FERDOUS Mohammad R. MASJEDIZADEH Wu LIN | United States United States United Kingdom | VU, JAKE MINH |
| 2020-10-05 | 17063061 | SALTS AND SOLID FORM OF A BTK INHIBITOR | PRINCIPIA BIOPHARMA INC. | Patented Case | 2022-06-28 | 11369613 | US20210015821A1 | Mohammad Reza MASJEDIZADEH Steven Gourlay | United States Australia | MURRAY, JEFFREY H |
| 2020-05-14 | 16764199 | IMMUNOPROTEASOME INHIBITORS | Principia Biopharma Inc. | Patented Case | 2024-07-02 | 12024531 | US20230133165A1 | Yan Lou Timothy Duncan Owens Kenneth Albert Brameld David Michael Goldstein | United States United States United States United States | O DELL, DAVID K |
| 2020-05-14 | 16764136 | IMMUNOPROTEASOME INHIBITORS | Principia Biopharma Inc. | Patented Case | 2022-01-18 | 11225493 | US20200277312A1 | Yan Lou Timothy Duncan Owens Kenneth Albert Brameld David Michael Goldstein | United States United States United States United States | SHAMEEM, GOLAM M |
| 2020-01-17 | 16745418 | PROCESSES FOR PREPARING AN FGFR INHIBITOR | Principia Biopharma, Inc. | Patented Case | 2021-01-26 | 10899760 | US20200148680A1 | Jiang ZHU Mohammad MASJEDIZADEH | United States United States | BERNHARDT, EMILY A |
| 2019-12-09 | 16708340 | SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINES AS KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. | Patented Case | 2021-06-22 | 11040980 | US20200190092A1 | Tim OWENS Erik VERNER | United States United States | WILLIS, DOUGLAS M |
| 2019-10-08 | 16596611 | SALTS AND SOLID FORM OF A BTK INHIBITOR | PRINCIPIA BIOPHARMA INC. | Patented Case | 2020-11-10 | 10828307 | US20200038405A1 | Mohammad Reza MASJEDIZADEH Steven GOURLAY | United States United States | MURRAY, JEFFREY H |
| 2019-10-04 | 16593352 | TREATMENT OF PEMPHIGUS | Principia Biopharma Inc. | Patented Case | 2021-03-16 | 10946008 | US20200101059A1 | Steven GOURLAY | United States | CHANDRAKUMAR, NIZAL S |
| 2019-07-26 | 16523979 | HETEROCYCLE COMPRISING TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. | Patented Case | 2021-10-26 | 11155544 | US20190345159A1 | David M. GOLDSTEIN Timothy D. OWENS | United States United States | RODRIGUEZ-GARCIA, VALERIE |
| 2019-07-17 | 16478788 | IMMUNOPROTEASOME INHIBITORS | Principia Biopharma Inc. | Patented Case | 2021-10-26 | 11154563 | US20190336515A1 | Yan Lou Timothy Duncan Owens Kenneth Albert Brameld David Michael Goldstein | United States United States United States United States | HABTE, KAHSAY |
| 2019-04-12 | 16383237 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | Principia Biopharma, Inc. | Patented Case | 2021-08-03 | 11078199 | US20190233418A1 | Erik VERNER Kenneth Albert BRAMELD | United States United States | SZNAIDMAN, MARCOS L |
| 2018-08-29 | 16116425 | SALTS AND SOLID FORM OF A BTK INHIBITOR | PRINCIPIA BIOPHARMA INC. | Patented Case | 2019-10-29 | 10456403 | US20190076435A1 | Mohammad Reza MASJEDIZADEH Steven GOURLAY | United States United States | MURRAY, JEFFREY H |
| 2018-05-11 | 15978041 | SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINES AS KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. | Patented Case | 2020-01-14 | 10533013 | US20180327413A1 | Tim OWENS Erik VERNER | United States United States | WILLIS, DOUGLAS M |
| 2018-01-29 | 15748212 | PROCESSES FOR PREPARING AN FGFR INHIBITOR | Principia Biopharma, Inc. | Patented Case | 2020-01-21 | 10538518 | US20180215756A1 | Jiang ZHU Mohammad MASJEDIZADEH | United States United States | BERNHARDT, EMILY A |
| 2017-11-20 | 15575448 | QUINOLONE DERIVATIVES AS FGFR INHIBITORS | Principia Biopharma, Inc. | Patented Case | 2020-01-21 | 10538517 | US20180155340A1 | Kenneth Albert BRAMELD Erik VERNER | United States United States | NORTHINGTON DAVIS, ZINNA |
| 2017-11-08 | 15806525 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | Principia Biopharma, Inc. | Patented Case | 2019-05-21 | 10294223 | US20180065960A1 | Erik VERNER Kenneth Albert BRAMELD | United States United States | SZNAIDMAN, MARCOS L |
| 2017-06-16 | 15537294 | TREATMENT OF PEMPHIGUS | Principia Biopharma Inc. | Patented Case | 2019-11-26 | 10485797 | US20180050027A1 | Steven GOURLAY | United States | CHANDRAKUMAR, NIZAL S |
| 2017-01-19 | 15410716 | TYROSINE KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. | Patented Case | 2017-06-27 | 9688676 | US20170129890A1 | Timothy D. OWENS | United States | DANIEL, LAURA M |
| 2016-12-19 | 15320155 | LMP7 INHIBITORS | PRINCIPIA BIOPHARMA INC. | Patented Case | 2020-05-19 | 10654843 | US20180208589A1 | Timothy Owens Kenneth Albert Brameld | United States United States | KENYON, JOHN S |
| 2016-08-25 | 15121605 | BENZIMIDAZOLE DERIVATIVES AS RLK AND ITK INHIBITORS | PRINCIPIA BIOPHARMA, INC. | Patented Case | 2018-04-03 | 9932329 | US20160368908A1 | Timothy OWENS Ronald J. HILL | United States United States | AGUIRRE, AMANDA L |
| 2016-08-19 | 15120293 | SALTS AND SOLID FORM OF A BTK INHIBITOR | PRINCIPIA BIOPHARMA INC. | Patented Case | 2018-10-09 | 10092569 | US20170065591A1 | Mohammad Reza MASJEDIZADEH Steven GOURLAY | United States United States | MURRAY, JEFFREY H |
| 2016-03-22 | 15077442 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | Principia Biopharma, Inc. | Patented Case | 2017-02-14 | 9567334 | US20160200725A1 | Erik VERNER Kenneth Albert BRAMELD | United States United States | SZNAIDMAN, MARCOS L |
| 2016-03-17 | 15022869 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA, INC. | Patented Case | 2017-11-14 | 9815834 | US20160229849A1 | Erik VERNER Kenneth Albert BRAMELD | United States United States | SZNAIDMAN, MARCOS L |
| 2016-01-15 | 14997330 | SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINES AS KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. | Patented Case | 2018-06-12 | 9994576 | US20160251358A1 | Tim OWENS Erik VERNER | United States United States | WILLIS, DOUGLAS M |
| 2015-11-06 | 14934885 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS | Principia Biopharma, Inc. | Patented Case | 2017-04-25 | 9630963 | US20160130268A1 | Kenneth Albert BRAMELD Erik VERNER | United States United States | BAKSHI, PANCHAM |
| 2015-05-20 | 14418484 | TREATMENT OF DRY EYE | PRINCIPIA BIOPHARMA INC. | Patented Case | 2017-02-21 | 9572811 | US20150182530A1 | Martin Babler Mary E. Gerritsen | United States United States | SHTERENGARTS, SAMANTHA L |
| 2015-05-19 | 14443705 | SUBSTITUTED PYRROLO[2,3-b]PYRAZINES AS JAK3 INHIBITORS | PRINCIPIA BIOPHARMA INC. | Patented Case | 2017-06-13 | 9676778 | US20150291600A1 | David Michael Goldstein Kenneth Albert Brameld Tim Owens | United States United States United States | WILLIS, DOUGLAS M |
| 2015-02-27 | 14424480 | BENZIMIDAZOLE DERIVATIVES AS ITK INHIBITORS | Principia Biopharma, Inc. | Patented Case | 2017-02-21 | 9573958 | US20150225412A1 | Kenneth Albert Brameld Timothy Owens | United States United States | STOCKTON, LAURA LYNNE |
| 2014-08-20 | 14464602 | PYRAZOLOPYRIMIDINE COMPOUNDS AS KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. | Patented Case | 2015-01-27 | 8940744 | US20140364410A1 | Tim OWENS Erik VERNER | United States United States | HENLEY III, RAYMOND J |
| 2014-07-25 | 14374788 | SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINES AS KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. | Patented Case | 2016-02-23 | 9266895 | US20150094295A1 | Tim Owens Erik Verner | United States United States | WILLIS, DOUGLAS M |
| 2014-07-25 | 14341421 | TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. | Patented Case | 2015-02-24 | 8962635 | US20140336382A1 | David Michael GOLDSTEIN | United States | MURRAY, JEFFREY H |
| 2014-04-17 | 14255842 | TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. | Patented Case | 2015-07-28 | 9090621 | US20140309223A1 | David Michael GOLDSTEIN | United States | MURRAY, JEFFREY H |
| 2014-02-20 | 14185687 | TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. | Patented Case | 2015-02-03 | 8946241 | US20140303190A1 | David Michael GOLDSTEIN | United States | MURRAY, JEFFREY H |
| 2013-06-27 | 13929179 | TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. | Patented Case | 2014-06-24 | 8759358 | David Michael GOLDSTEIN | United States | MURRAY, JEFFREY H | |
| 2013-06-27 | 13929004 | TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. | Patented Case | 2014-03-18 | 8673925 | David Michael Goldstein | MURRAY, JEFFREY H | ||
| 2013-04-09 | 13859569 | TYROSINE KINASE INHIBITORS | Principia Biopharma, Inc. | Patented Case | 2015-02-17 | 8957080 | US20140303161A1 | David Michael GOLDSTEIN Kenneth Albert BRAMELD | United States United States | MURRAY, JEFFREY H |