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Denali Therapeutics Inc. (DNLI) Spending and interest coverage

Denali Therapeutics Inc. (DNLI) Spending and interest coverage

  • R&D / revenue · 12 months: Value 11118.76%; Formula and calculation Research and development expense / revenue. Period ending 2026-06-30..
  • Stock-based compensation / revenue · 12 months: Value 2638.40%; Formula and calculation Share-based compensation / revenue. Period ending 2026-06-30..
  • Interest coverage · 12 months: Value (m); Formula and calculation Estimated: average term debt × dated USD coupon proxy + average commercial paper × matching-currency disclosed rate at or before period end. Swaps, foreign-exchange, lease interest and amortization are not quantified..

Spending and interest coverage

Overview →

Financial period ending 2026-06-30; current quote (m). Amounts retain their stated periods and units.

MetricValueFormula and calculation
R&D / revenue · 12 months11118.76%Research and development expense / revenue. Period ending 2026-06-30.

$400.72M ÷ $3.60M × 100 ≈ 11118.76%

Stock-based compensation / revenue · 12 months2638.40%Share-based compensation / revenue. Period ending 2026-06-30.

$95.09M ÷ $3.60M × 100 ≈ 2638.40%

Interest coverage · 12 months(m)Estimated: average term debt × dated USD coupon proxy + average commercial paper × matching-currency disclosed rate at or before period end. Swaps, foreign-exchange, lease interest and amortization are not quantified.

Calculation unavailable: missing inputs remain (m).

Calculation inputs

InputAmount with unitRaw financial data
Research and development spending400.72M USDResearch and Development Expense
Revenue3.60M USDRevenue from Contract with Customer, Excluding Assessed Tax
Stock-based compensation95.09M USDShare-based Payment Arrangement, Noncash Expense
Operating income-542.70M USDOperating Income (Loss)
Interest expense · reported / estimated(m) · Estimated expense assumptions

Latest interest expense basis: (m). Estimated values carry *; expand each history row’s basis for its dated balances and rate assumptions.

Calculated history

Changes compare with the next older row (previous quarter), unless explicitly labeled otherwise. Rolling 12-month growth compares two successive quarter-end rolling totals; it is not year-over-year growth.

Period endingResearch and development spending (USD)Revenue (USD)Stock-based compensation (USD)Operating income (USD)Interest expense · reported / estimated (USD)R&D / revenueSBC / revenueInterest coverageInterest expense basis
2026-06-30$400.72M$3.60M$95.09M$-542.70M(m)11118.76%2638.40%(m)(m)
2026-03-31$406.40M(m)$97.56M$-547.12M(m)(m)(m)(m)(m)
2025-12-31$418.78M$0.00$99.63M$-555.34M(m)(m)(m)(m)(m)
2025-09-30$420.66M(m)$100.76M$-547.82M(m)(m)(m)(m)(m)
2025-06-30$416.95M(m)$100.48M$-533.58M(m)(m)(m)(m)(m)
2025-03-31$405.65M(m)$100.20M$-515.21M(m)(m)(m)(m)(m)
2024-12-31$396.44M$0.00$102.88M$-487.34M(m)(m)(m)(m)(m)
2024-09-30$404.46M$0.00$103.79M$-490.07M(m)(m)(m)(m)(m)
2024-06-30$395.95M$1.27M$106.39M$-480.68M(m)31251.38%8396.84%(m)(m)
2024-03-31$402.08M$295.39M$107.86M$-193.60M(m)136.12%36.51%(m)(m)
2023-12-31$423.88M$330.53M$108.10M$-196.70M(m)128.24%32.71%(m)(m)
2023-09-30$408.18M$340.79M$107.30M$-169.47M(m)119.78%31.49%(m)(m)
2023-06-30$406.23M$339.71M$104.42M$-163.16M(m)119.58%30.74%(m)(m)
2023-03-31$401.45M$98.06M$101.79M$-395.06M(m)409.37%103.79%(m)(m)
2022-12-31$358.73M$105.06M$99.85M$-340.74M(m)341.44%95.03%(m)(m)
2022-09-30$334.50M$107.32M$96.75M$-312.52M(m)311.68%90.15%(m)(m)
2022-06-30$318.27M$112.42M$93.16M$-290.63M(m)283.11%82.87%(m)(m)
2022-03-31$291.24M$82.88M$90.36M$-291.03M(m)351.42%109.04%(m)(m)
2021-12-31$265.35M$48.66M$85.25M$-295.75M(m)545.35%175.20%(m)(m)
2021-09-30$252.22M$352.95M$76.99M$25.45M(m)71.46%21.81%(m)(m)
2021-06-30$234.37M$357.06M$69.25M$50.92M(m)65.64%19.39%(m)(m)
2021-03-31$221.81M$339.93M$60.59M$51.47M(m)65.25%17.83%(m)(m)
2020-12-31$212.62M$335.56M$50.35M$62.72M(m)63.36%15.01%(m)(m)
2020-09-30$209.42M$23.71M$45.41M$-239.12M(m)883.19%191.51%(m)(m)
2020-06-30$208.26M$27.83M$41.06M$-229.16M(m)748.29%147.52%(m)(m)
2020-03-31$207.00M$26.12M$42.29M$-230.64M(m)792.51%161.91%(m)(m)
2019-12-31$193.38M$26.68M$38.38M$-213.18M(m)724.87%143.86%(m)(m)
2019-09-30$181.74M$147.68M$35.13M$-80.70M(m)123.06%23.79%(m)(m)
2019-06-30$159.52M$135.27M$31.74M$-68.51M(m)117.92%23.47%(m)(m)
2019-03-31$159.77M$132.72M$22.74M$-63.13M(m)120.38%17.13%(m)(m)
2018-12-31$143.18M$129.16M$18.79M$-46.37M(m)110.86%14.55%(m)(m)
2018-09-30(m)(m)(m)(m)(m)(m)(m)(m)(m)
2018-06-30(m)(m)(m)(m)(m)(m)(m)(m)(m)
2018-03-31(m)(m)(m)(m)(m)(m)(m)(m)(m)
2017-12-31$74.46M$0.00$4.41M$-90.14M(m)(m)(m)(m)(m)
2017-09-30(m)(m)(m)(m)(m)(m)(m)(m)(m)
2017-06-30(m)(m)(m)(m)(m)(m)(m)(m)(m)
2017-03-31(m)(m)(m)(m)(m)(m)(m)(m)(m)
2016-12-31$75.70M$0.00$2.95M$-87.43M(m)(m)(m)(m)(m)

(m) means missing inputs. Historical market-based ratios use the saved close on or immediately before period ending and that period’s reported shares; current quotes are not substituted. Five-year projections repeat historical CAGR, not analyst forecasts.

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