| 2026-09-22 | 8-K | 10.1 | Form of Indemnification Agreement. |
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| 2026-08-18 | 8-K | 10.1 | First Amendment to Form of Registration Rights Agreement. |
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| 2025-12-30 | 8-K | 10.1 | Restricted Stock Unit Grant Agreement, dated December 23, 2025, by and between the Company and CoinXit Ltd. |
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| 2025-12-16 | 8-K | 10.1 | 2025 Cypherpunk Technologies Inc. Equity Incentive Plan. |
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| 2025-11-12 | 8-K | 10.7 | Form of Employee Restricted Stock Unit Agreement pursuant to the 2022 Equity Incentive Plan. |
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| 2025-11-12 | 8-K | 10.6 | Form of Employee Restricted Stock Unit Agreement pursuant to the 2016 Equity Incentive Plan. |
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| 2025-11-12 | 8-K | 10.5 | Form of Director Restricted Stock Unit Agreement pursuant to the 2022 Equity Incentive Plan. |
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| 2025-11-12 | 8-K | 10.4 | Form of Director Restricted Stock Unit Agreement pursuant to the 2016 Equity Incentive Plan. |
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| 2025-11-12 | 8-K | 10.3 | Executive Employment Agreement, dated November 11, 2025, by and between the Company and William McEvoy |
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| 2025-11-12 | 8-K | 10.2 | Restricted Stock Unit Grant Agreement, dated November 11, 2025, by and between the Company and CoinXit Ltd. |
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| 2025-11-12 | 8-K | 10.1 | Consulting Agreement, dated November 11, 2025, by and between the Company and CoinXit Ltd. |
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| 2025-10-09 | 8-K | 10.3 | Lead Investor Agreement |
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| 2025-10-09 | 8-K | 10.2 | Form of Registration Rights Agreement |
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| 2025-10-09 | 8-K | 10.1 | Form of Securities Purchase Agreement |
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| 2025-08-14 | 10-Q | 10.1 | Fifth Amendment to Lease by and between Bulfinch Square Limited Partnership and Leap Therapeutics, Inc. dated as of July 1, 2025. |
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| 2024-08-12 | 10-Q | 10.2 | First Amended and Restated Collaboration Agreement, dated April 2, 2024, by and between Adimab, LLC and Leap Therapeutics, Inc. |
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| 2024-05-13 | 10-Q | 10.1 | Fourth Amendment to Lease by and between Bulfinch Square Limited Partnership and Leap Therapeutics, Inc. dated as of January 3, 2024 |
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| 2024-04-11 | 8-K | 10.1 | Form of Securities Purchase Agreement by and among the Company and the purchasers named therein |
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| 2024-03-18 | 10-K | 10.33 | Amendment No. 1 to Leap Therapeutics, Inc. 2022 Equity Incentive Plan |
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| 2023-05-15 | 10-Q | 10.7 | First Amendment to Executive Employment Agreement, dated April 3, 2023, by and between the Company and Jason S. Baum. |
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| 2023-05-15 | 10-Q | 10.6 | Executive Employment Agreement, by and between the Company and Jason S. Baum. |
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| 2023-05-15 | 10-Q | 10.5 | Second Amendment to Executive Employment Agreement, dated April 3, 2023, by and between the Company and John Mark O’Mahony. |
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| 2023-05-15 | 10-Q | 10.2 | Collaboration Agreement, dated August 10, 2020, by and between Adimab, LLC and Flame Biosciences, Inc. |
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| 2023-05-15 | 10-Q | 10.1 | Strategic Partnership and License Agreement, dated August 13, 2021, by and between NovaRock Biotherapeutics Ltd. and Flame Biosciences, Inc. |
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| 2023-04-07 | 8-K | 10.1 | Second Amendment to Executive Employment Agreement, by and between the Company and Dr. Cynthia Sirard, dated as of April 3, 2023. |
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| 2023-03-16 | 8-K | 10.1 | Continuing Clinical Collaboration Letter Agreement |
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| 2023-01-23 | 8-K | 10.3 | Registration Rights Agreement, dated January 17, 2023, by and among the Company and the Holders. |
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| 2023-01-23 | 8-K | 10.2 | Support Agreement by and between Leap Therapeutics, Inc. and HealthCare Ventures VIII Liquidating Trust, dated January 17, 2023. |
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| 2023-01-23 | 8-K | 10.1 | Support Agreement by and between Leap Therapeutics, Inc. and HealthCare Ventures IX L.P., dated January 17, 2023. |
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| 2022-08-12 | 10-Q | 10.1 | Third Amendment to Lease by and between Bullfinch Square Limited Partnership and Leap Therapeutics, Inc., dated as of May 16, 2022. |
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| 2022-03-11 | 10-K | 10.27 | Second Amendment to Lease by and between Bulfinch Square Limited Partnership and Leap Therapeutics, Inc. dated as of October 1, 2021. |
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| 2021-11-12 | 10-Q | 10.1 | First Amendment to Lease by and between Bullfinch Square Limited Partnership and Leap Therapeutics, Inc., dated as of August 17, 2021. |
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| 2021-08-13 | 10-Q | 10.2 | First Amendment, dated as of April 20, 2021, to Employment Agreement, by and between the Company and John Mark O’Mahony, dated as of April 10, 2020. |
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| 2021-08-13 | 10-Q | 10.1 | First Amendment, dated as of April 15, 2021, to Employment Agreement, by and between the Company and Cynthia Sirard, dated as of April 10, 2020. |
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| 2021-03-12 | 10-K | 10.19 | Employment Agreement, by and between the Company and John Mark O’ Mahony, dated as of April 10, 2020. |
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| 2021-03-12 | 10-K | 10.18 | Employment Agreement, by and between the Company and Cynthia Sirard, dated as of April 10, 2020. |
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| 2020-11-12 | 10-Q | 10.1 | Employment Agreement, by and between the Company and Christine Granfield, dated as of August 16, 2020. |
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| 2020-05-14 | 10-Q | 10.1 | Exclusive Option and License Agreement dated as of January 3, 2020, by and between the Company and BeiGene, Ltd. |
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| 2020-04-15 | 8-K/A | 10.1 | Employment Agreement, by and between the Company and Douglas E. Onsi, dated as of April 10, 2020. |
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| 2020-01-07 | 8-K | 10.5 | Registration Rights Agreement dated as of January 3, 2020, by and between the Company and the persons listed on the attached Schedule A thereto. |
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| 2020-01-07 | 8-K | 10.4 | Registration Rights Agreement dated as of January 3, 2020, by and between the Company and the persons listed on the attached Schedule A thereto. |
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| 2020-01-07 | 8-K | 10.3 | Form of Voting Agreement. |
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| 2020-01-07 | 8-K | 10.2 | Placement Agency Agreement, dated January 3, 2020, by and between the Company and Raymond James & Associates, Inc. |
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| 2020-01-07 | 8-K | 10.1 | Securities Purchase Agreement, dated January 3, 2020, by and among the Company and the institutional investors named therein. |
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| 2019-07-11 | 8-K | 10.3 | Registration Rights Agreement dated as of July 10, 2019, by and between the Company and Lincoln Park Capital Fund, LLC. |
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| 2019-07-11 | 8-K | 10.2 | Purchase Agreement dated as of July 10, 2019, by and between the Company and Lincoln Park Capital Fund, LLC. |
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| 2019-07-11 | 8-K | 10.1 | Purchase Agreement dated as of July 11, 2019, by and between the Company and Lincoln Park Capital Fund, LLC. |
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| 2017-11-17 | 8-K | 10.3 | Voting Agreement, dated as of November 14, 2017, by and among Leap Therapeutics, Inc., HealthCare Ventures VIII, L.P., HealthCare Ventures IX, L.P. and HealthCare Ventures Strategic Fund, L.P. |
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| 2017-11-17 | 8-K | 10.2 | Placement Agency Agreement, dated as of November 14, 2017, by and between Leap Therapeutics, Inc., Raymond James & Associates, Inc. and Ladenburg Thalmann & Co. Inc. |
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| 2017-11-17 | 8-K | 10.1 | Form of Purchase Agreement, dated as of November 14, 2017, by and among Leap Therapeutics, Inc. and the purchasers identified on the schedule thereto. |
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| 2017-03-31 | 10-K | 10.29 | CONSENT TO ASSIGNMENT AND ASSUMPTION OF LEASE |
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| 2017-03-31 | 10-K | 10.28 | FIRST AMENDMENT TO LEASE |
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| 2017-03-31 | 10-K | 10.27 | AMENDMENT TO LEASE |
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| 2017-03-31 | 10-K | 10.26 | LEASE |
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| 2017-03-31 | 10-K | 10.2 | LEAP THERAPEUTICS, INC. |
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| 2017-01-26 | 8-K | 10.4 | Subscription Agreement |
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| 2017-01-26 | 8-K | 10.3 | Registration Rights Agreement |
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| 2017-01-26 | 8-K | 10.2 | Letter Agreement |
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| 2017-01-26 | 8-K | 10.1 | Royalty Agreement |
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