CYBERONICS INC Clinical Trials
Studies registered on ClinicalTrials.gov (U.S. National Library of Medicine) with the company as lead sponsor or collaborator, newest start first. Values are as registered.
- 2015-08: Study NCT02545582; Company role Lead sponsor; Phase Observational; Status Suspended.
- 2015-04-28: Study NCT02385526; Company role Lead sponsor; Phase Observational; Status Completed.
- 2014-08: Study NCT03163030; Company role Lead sponsor; Phase Not applicable; Status Completed.
- 2013-07: Study NCT01846741; Company role Lead sponsor; Phase Not applicable; Status Completed.
| Start date | Study | Company role | Phase | Status | Conditions | Enrollment | Completion date |
|---|---|---|---|---|---|---|---|
| 2015-08 | NCT02545582 VITARIA Registry Study | Lead sponsor | Observational | Suspended | Congestive Heart Failure | 200 | 2019-12 |
| 2015-04-28 | NCT02385526 Vagus Nerve Stimulation Titration Protocol to Improve Tolerance and Accelerate Adaptation | Lead sponsor | Observational | Completed Results posted | Epilepsy; Seizures | 67 | 2016-10-10 |
| 2014-08 | NCT03163030 Autonomic Regulation Therapy in Heart Failure With Preserved Ejection Fraction | Lead sponsor | Not applicable | Completed | Congestive Heart Failure | 52 | 2021-12 |
| 2013-07 | NCT01846741 VNS Therapy Automatic Magnet Mode Outcomes Study in Epilepsy Patients Exhibiting Ictal Tachycardia (E-37) | Lead sponsor | Not applicable | Completed Results posted | Epilepsy | 20 | 2015-08 |
| 2012-07 | NCT01823887 Autonomic Neural Regulation Therapy to Enhance Myocardial Function in Heart Failure (ANTHEM-HF) Study | Lead sponsor | Phase 1, Phase 2 | Completed | Congestive Heart Failure | 60 | 2014-06 |
| 2012-06 | NCT01626599 Study to Evaluate a New Device Designed to Collect Heart Activity and Body Movement Data | Lead sponsor | Not applicable | Completed | Epilepsy | 147 | 2014-04 |
| 2012-05 | NCT01612689 3-Dimensional Accelerometer Sub-Study | Lead sponsor | Not applicable | Completed | Epilepsy | 16 | 2014-07 |
| 2011-11 | NCT01486056 ECG Vector Determination | Lead sponsor | Observational | Completed | Epilepsy | 29 | 2012-01 |
| 2011-11 | NCT01485016 Physiological and Biomechanical Data Collection Study in Epilepsy Subjects | Lead sponsor | Observational | Completed | Epilepsy | 20 | 2012-07 |
| 2011-03 | NCT01325623 Seizure Detection and Automatic Magnet Mode Performance Study | Lead sponsor | Not applicable | Completed Results posted | Epilepsy | 31 | 2015-07 |
| 2011-03 | NCT01281280 PuLsE 2-Observational Long-Term Effectiveness Follow-Up Study of PuLsE 1 | Lead sponsor | Observational | Completed | Epilepsy | 81 | 2014-04 |
| 2011-01 | NCT01281293 Vagus Nerve Stimulation Clinical Outcomes Measured Prospectively in Patients Stimulated | Lead sponsor | Observational | Completed | Epilepsy | 124 | 2018-08-16 |
| 2010-12 | NCT01268007 Heartbeat Sensitivity Calibration Using the ECG Accessory | Lead sponsor | Observational | Completed | ECG Comparisons in Normal Healthy Subject | 1 | 2010-12 |
| 2010-09 | NCT01214707 Heart Rate Changes During Normal Activity, Exercise, and Seizures in Subjects With Epilepsy | Lead sponsor | Observational | Completed | Epilepsy | 30 | |
| 2010-09 | NCT01202682 Heart Rate Changes During Normal Activity, Exercise, and Sleep in Normal Healthy Subjects With and Without Epilepsy | Lead sponsor | Observational | Completed | Healthy; Exercise | 50 | 2010-10 |
| 2010-08 | NCT01202669 Heart Rate Changes in Subjects With Epilepsy | Lead sponsor | Observational | Completed | Epilepsy | 98 | 2014-07 |
| 2007-09 | NCT00625222 Transcranial Direct Current Stimulation (tDCS) As A Tool For Prospective Responder Identification Before Vagus Nerve Stimulation (VNS) Implantation | Collaborator Lead: University of Luebeck | Not applicable | Unknown | Epilepsy | 70 | 2010-06 |
| 2006-02 | NCT00522418 Study Comparing Best Medical Practice With or Without VNS Therapy in Pharmacoresistant Partial Epilepsy Patients | Lead sponsor | Phase 4 | Terminated Results posted | Epilepsy; Partial Epilepsy | 122 | 2008-07 |
| 2006-01 | NCT00320372 Treatment-Resistant Depression Registry | Lead sponsor | Observational | Completed Results posted | Major Depressive Disorder | 795 | 2015-05 |
| 2006-01 | NCT00305565 Study Comparing Outcomes for Patients With Treatment Resistant Depression Who Receive VNS Therapy at Different Doses | Lead sponsor | Phase 4 | Completed Results posted | Depression | 331 | 2010-02 |
| 2005-02 | NCT00215215 Effectiveness Study Comparing Treatment With Drug(s) or Adjunctive VNS Therapy for Pharmacoresistant Partial Seizures | Lead sponsor | Phase 4 | Terminated | Epilepsies, Partial | 360 | 2007-11 |
| 2004-10 | NCT01118455 Trial to Assess Vagus Nerve Stimulation Therapy vs. Anti-Epileptic Drug (AED) Treatment in Children With Refractory Seizures | Lead sponsor | Phase 4 | Terminated Results posted | Epilepsy | 134 | 2010-01 |
| 2000-07 | NCT00533832 Pivotal Trial (D02) of Vagus Nerve Stimulation (VNS) for Treatment-Resistant Depression (TRD) | Lead sponsor | Not applicable | Completed | Major Depressive Disorder | 266 | 2005-07 |