Achaogen, Inc. Clinical Trials
Studies registered on ClinicalTrials.gov (U.S. National Library of Medicine) with the company as lead sponsor or collaborator, newest start first. Values are as registered.
- 2017-08-31: Study NCT03270553; Company role Lead sponsor; Phase Phase 1; Status Completed.
- 2017-06-16: Study NCT03177278; Company role Lead sponsor; Phase Phase 1; Status Completed.
- 2017-05-17: Study NCT03163550; Company role Lead sponsor; Phase Phase 1; Status Completed.
- 2016-01-11: Study NCT02486627; Company role Lead sponsor; Phase Phase 3; Status Completed.
| Start date | Study | Company role | Phase | Status | Conditions | Enrollment | Completion date |
|---|---|---|---|---|---|---|---|
| 2017-08-31 | NCT03270553 A Study to Assess the Effect of Plazomicin on the Pharmacokinetics of Metformin | Lead sponsor | Phase 1 | Completed | Healthy Volunteers | 16 | 2017-10-07 |
| 2017-06-16 | NCT03177278 A Study to Assess the Metabolism, Excretion, and Mass Balance of Radio-Labeled Plazomicin | Lead sponsor | Phase 1 | Completed | Healthy Volunteers | 6 | 2017-07-10 |
| 2017-05-17 | NCT03163550 A Study to Assess the Safety, Tolerability, Pharmacokinetics, Food Effect, and Drug-Drug Interaction Potential of ACHN-383 and ACHN-789 | Lead sponsor | Phase 1 | Completed | Healthy Volunteers | 40 | 2017-10-15 |
| 2016-01-11 | NCT02486627 A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP) | Lead sponsor | Phase 3 | Completed Results posted | Complicated Urinary Tract Infection; Acute Pyelonephritis | 609 | 2016-09-22 |
| 2014-09-16 | NCT01970371 A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) | Lead sponsor | Phase 3 | Completed Results posted | Bloodstream Infections (BSI) Due to CRE; Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE; Ventilator-Associated Bacterial Pneumonia (VABP) Due to CRE; Complicated Urinary Tract Infection (cUTI) Due to CRE; Acute Pyelonephritis (AP) Due to CRE | 69 | 2016-09-15 |
| 2013-05 | NCT01870245 A Multiple Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers | Lead sponsor | Phase 1 | Terminated | Healthy Volunteer | 4 | |
| 2012-05 | NCT01597947 A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers | Lead sponsor | Phase 1 | Completed | Healthy Volunteer | 50 | 2012-12 |
| 2011-10 | NCT01514929 A Study to Evaluate the Effect of IV ACHN-490 Injection on the QT/QTc Interval in Healthy Volunteers | Lead sponsor | Phase 1 | Completed | Cardiac Effects in Normal Healthy Volunteers | 64 | 2012-03 |
| 2011-09 | NCT01462136 PK Study of ACHN-490 Injection in Renally Impaired Subjects | Lead sponsor | Phase 1 | Completed | Renal Insufficiency | 24 | |
| 2010-07-13 | NCT01096849 A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP) | Lead sponsor | Phase 2 | Completed Results posted | Complicated Urinary Tract Infection; Acute Pyelonephritis | 145 | 2012-04-03 |
| 2010-01 | NCT01034774 Phase 1 Study to Determine Safety, Blood PK and Lung Penetration | Lead sponsor | Phase 1 | Completed | Healthy Volunteers | 40 | 2010-07 |
| 2009-01 | NCT00822978 Phase 1 Study for Safety of ACHN-490 | Lead sponsor | Phase 1 | Completed | Healthy | 39 | 2009-10 |