| 2026-08-04 | 10-Q | 10.4 | Second Amendment to Revenue Interest Financing Agreement dated June 29, 2026, between Rhythm Pharmaceuticals, Inc. and HCR Rhythm SPV, LLC |
|---|
| 2026-08-04 | 10-Q | 10.3 | First Amendment to Revenue Interest Financing Agreement dated March 27, 2024, between Rhythm Pharmaceuticals, Inc. and HCR Rhythm SPV, LLC |
|---|
| 2026-08-04 | 10-Q | 10.2 | Severance Letter Agreement Dated June 25, 2026, between Rhythm Pharmaceuticals, Inc. and Pamela Cramer |
|---|
| 2026-08-04 | 10-Q | 10.1 | Rhythm Pharmaceuticals, Inc. Non-Employee Director Compensation Program |
|---|
| 2026-05-05 | 10-Q | 10.1 | Rhythm Pharmaceuticals, Inc. Deferred Compensation Plan (Directors) |
|---|
| 2026-02-26 | 10-K | 10.17 | Offer Letter, dated May 20, 2024, by and between the Registrant and Alastair Garfield. |
|---|
| 2025-08-05 | 10-Q | 10.1 | Non-Employee Director Compensation Program |
|---|
| 2024-08-06 | 10-Q | 10.1 | Non-Employee Director Compensation Program. |
|---|
| 2024-05-07 | 10-Q | 10.5 | Third Amendment to Lease, dated May 2, 2024, by and between the Registrant and 500 Boylston & 222 Berkeley Owner (DE) LLC. |
|---|
| 2024-05-07 | 10-Q | 10.4 | Rhythm Pharmaceuticals, Inc. 2017 Equity Incentive Plan Performance Unit Agreement |
|---|
| 2024-05-07 | 10-Q | 10.1 | Summary of Non-Employee Director Compensation Policy. |
|---|
| 2024-04-01 | 8-K | 10.1 | Investment Agreement, dated as of April 1, 2024, by and among Rhythm Pharmaceuticals, Inc., and the investors named therein |
|---|
| 2024-02-29 | 10-K | 10.25 | Exclusive License Agreement, dated January 4, 2024, by and between Rhythm Pharmaceuticals, Inc. and LG Chem, Ltd. |
|---|
| 2024-02-29 | 10-K | 10.6 | Summary of Non-Employee Director Compensation Policy |
|---|
| 2023-08-03 | 8-K | 10.4 | Amended & Restated Offer Letter, dated August 3, 2023, by and between the Registrant and Hunter Smith. |
|---|
| 2023-08-03 | 8-K | 10.3 | Amended & Restated Offer Letter, dated August 3, 2023, by and between the Registrant and Jennifer Chien. |
|---|
| 2023-08-03 | 8-K | 10.2 | Amended & Restated Offer Letter, dated July 28, 2023, by and between the Registrant and Joseph Shulman. |
|---|
| 2023-08-03 | 8-K | 10.1 | Amended & Restated Offer Letter, dated July 28, 2023, by and between the Registrant and Daivd P. Meeker. |
|---|
| 2023-03-01 | 10-K | 10.20 | Offer Letter, dated June 23, 2020, by and between the Registrant and Joseph Shulman. |
|---|
| 2023-03-01 | 10-K | 10.6 | Summary of Non-Employee Director Compensation Policy |
|---|
| 2022-08-03 | 10-Q | 10.1 | Revenue Interest Financing Agreement, dated June 16, 2022, by and between the Company and entities managed by HealthCare Royalty Management, LLC |
|---|
| 2022-03-01 | 10-K | 10.21.2 | Consulting Agreement, dated September 11, 2021, by and between the Registrant and Murray Stewart, D.M., F.R.C.P. |
|---|
| 2022-03-01 | 10-K | 10.10 | License Agreement, dated December 3, 2021, by and between the Registrant and RareStone Group Ltd. |
|---|
| 2022-03-01 | 10-K | 10.6 | Summary of Non-Employee Director Compensation Policy |
|---|
| 2022-03-01 | 10-K | 10.5.2 | 2022 Employment Inducement Plan Form of Restricted Stock Unit Agreement |
|---|
| 2022-03-01 | 10-K | 10.5.1 | 2022 Employment Inducement Plan and Form of Option Agreement |
|---|
| 2021-11-02 | 10-Q | 10.2 | Offer Letter, dated September 1, 2021, by and between the Registrant and Linda Shapiro Manning, M.D. |
|---|
| 2021-08-03 | 10-Q | 10.1 | Offer Letter, dated July 9, 2021, by and between the Registrant and Pamela Cramer. |
|---|
| 2021-03-01 | 10-K | 10.16 | Offer Letter, dated September 25, 2020, by and between the Registrant and Jennifer Chien. |
|---|
| 2021-03-01 | 10-K | 10.15 | Offer Letter, dated September 14, 2018, by and between the Registrant and Murray Stewart M.D. |
|---|
| 2021-03-01 | 10-K | 10.14 | Offer Letter, dated May 10, 2018, by and between the Registrant and Simon D. Kelner. |
|---|
| 2021-03-01 | 10-K | 10.5 | Summary of Non-Employee Director Compensation Policy |
|---|
| 2020-11-02 | 10-Q | 10.2 | Separation Agreement, dated September 30, 2020, between Rhythm Pharmaceuticals, Inc. and Nithya Desikan. |
|---|
| 2020-11-02 | 10-Q | 10.1 | Offer Letter, dated September 4, 2020, and Indefinite Term Employment Contract, dated October 5, 2020, between Rhythm Pharmaceuticals, Inc. and Yann Mazabraud. |
|---|
| 2020-08-03 | 10-Q | 10.1 | Amendment No. 2 to Development and Manufacturing and Services Agreement, dated as of July 15, 2020, by and between the Company and Corden Pharma Brussels S.A. |
|---|
| 2020-07-21 | 8-K | 10.1 | Offer Letter, dated July 16, 2020, between Rhythm Pharmaceuticals, Inc. and David P. Meeker, M.D. |
|---|
| 2020-05-04 | 10-Q | 10.3 | Amendment No. 1 to Development and Manufacturing and Services Agreement, dated as of February 20, 2020, by and between the Company and Corden Pharma Brussels S.A. |
|---|
| 2020-05-04 | 10-Q | 10.2 | Offer Letter, dated December 21, 2017, by and between the Company and Hunter C. Smith. |
|---|
| 2020-05-04 | 10-Q | 10.1 | Summary of Non-Employee Director Compensation Policy. |
|---|
| 2020-03-02 | 10-K | 10.18 | Form of Restricted Stock Unit Award Agreement. |
|---|
| 2020-01-08 | 8-K | 10.2 | Consulting Agreement dated January 6, 2020. |
|---|
| 2020-01-08 | 8-K | 10.1 | Separation Agreement and General Release dated January 6, 2020. |
|---|
| 2019-07-25 | 8-K | 10.1 | Summary of Non-Employee Director Compensation Policy. |
|---|
| 2019-03-08 | 10-K | 10.15 | Offer Letter, dated September 13, 2017, by and between the Registrant and Lex H.T. Van der Ploeg. |
|---|
| 2019-03-08 | 10-K | 10.9 | First Amendment to Lease, dated April 15, 2016. |
|---|
| 2018-08-09 | 8-K | 10.1 | Second Amendment to Lease, dated August 6, 2018. |
|---|
| 2018-08-08 | 10-Q | 10.4 | Offer Letter, dated September 13, 2017, by and between the Company and Nithya Desikan. |
|---|
| 2018-08-08 | 10-Q | 10.3 | Offer Letter, dated September 13, 2017, by and between the Company and Hunter Smith. |
|---|
| 2018-08-08 | 10-Q | 10.2 | Offer Letter, dated September 13, 2017, by and between the Company and Keith M. Gottesdiener. |
|---|
| 2018-05-14 | 10-Q | 10.2 | Summary of Non-Employee Director Compensation Policy. |
|---|
| 2018-05-14 | 10-Q | 10.1 | License Agreement dated March 30, 2018, by and between the Company and Takeda Pharmaceutical Company Limited. |
|---|
| 2017-11-14 | 10-Q | 10.10 | Rhythm Pharmaceuticals, Inc. 2017 Employee Stock Purchase Plan. |
|---|
| 2017-11-14 | 10-Q | 10.2 | 2017 Equity Incentive Plan and Form of Option Agreement and Notice of Exercise. |
|---|