| 2026-08-05 | 10-Q | 10.7 | Amended and Restated Change in Control Severance Agreement, dated July 13, 2026, by and between the Registrant and Ron Kurtz. |
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| 2026-08-05 | 10-Q | 10.6 | Transition Employment Letter Agreement, dated July 13, 2026, by and between the Registrant and Ron Kurtz. |
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| 2026-08-05 | 10-Q | 10.5 | Amendment to Change in Control and Severance Agreement, dated April 17, 2026, by and between the Registrant and Ron Kurtz. |
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| 2026-08-05 | 10-Q | 10.4 | Consulting Agreement, dated June 1, 2026, by and between the Registrant and Systemize Partners, LLC. |
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| 2026-08-05 | 10-Q | 10.3 | Collaboration Agreement, dated June 30, 2026, by and between the Registrant and Alcon Pharmaceuticals, Ltd. |
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| 2026-08-05 | 10-Q | 10.2 | Change in Control Severance Agreement, by and between the Registrant and Aziz Mottiwala, dated as of July 13, 2026. |
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| 2026-08-05 | 10-Q | 10.1 | Employment Letter, by and between the Registrant and Aziz Mottiwala, dated July 13, 2026. |
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| 2026-02-25 | 10-K | 10.33 | Consulting Agreement, by and between Registrant and Shelley Thunen, dated December 22, 2025 |
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| 2026-02-25 | 10-K | 10.32 | Transition and Release Agreement, by and between the Registrant and Shelley Thunen, dated as of December 22, 2025. |
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| 2026-02-25 | 10-K | 10.31 | Change in Control and Severance Agreement, by and between the Registrant and Mark Wilterding, dated as of December 15,2025. |
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| 2026-02-25 | 10-K | 10.30 | Change in Control and Severance Agreement, by and between the Registrant and Scott Gaines, dated as of July 27, 2022. |
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| 2026-02-25 | 10-K | 10.25 | Confirmatory Employment Letter, by and between the Registrant and Mark Wilterding, dated December 15, 2025, as Amended. |
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| 2026-02-25 | 10-K | 10.24 | Offer Letter by and between the Registrant and Scott Gaines, dated October 28, 2015, as Amended. |
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| 2026-02-25 | 10-K | 10.19 | First Amendment to Lease, dated as of March 27, 2020, by and between Pacific Park Investments, Inc. and the Registrant, for premises located at 75 Columbia, Aliso Viejo, California 92656. |
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| 2025-02-25 | 10-K | 10.33 | Outside Director Compensation Policy |
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| 2025-02-25 | 10-K | 10.13 | Seventh Amendment (extension to the lease), dated as of November 6, 2024, by and between the Registrant and Accuride International Inc., for premises located at 120 Columbia, Suites 300-500, Aliso Viejo, California 92656. |
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| 2025-02-25 | 10-K | 10.3 | 2021 Equity Incentive Plan of the registrant, as amended, and forms of agreement thereunder. |
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| 2024-11-07 | 10-Q | 10.1 | Amendment # 3 to the Sublease Agreement |
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| 2024-08-05 | 10-Q | 10.6 | SUBLEASE CANCEL |
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| 2024-08-05 | 10-Q | 10.5 | 100-150 COLUMBIA SIXTH AMENDMENT |
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| 2024-08-05 | 10-Q | 10.4 | 100-150 COLUMBIA FIFTH AMENDMENT |
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| 2024-08-05 | 10-Q | 10.3 | 5 COLUMBIA AMENDMENT #3 |
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| 2024-08-05 | 10-Q | 10.2 | 5 COLUMBIA AMENDMENT #2 |
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| 2024-08-05 | 10-Q | 10.1 | 125 COLUMBIA |
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| 2024-02-28 | 10-K | 10.27 | Outside Director Compensation Policy |
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| 2023-07-05 | 8-K | 10.1 | Loan and Security Agreement, by and among the Company, Oxford, as collateral agent thereunder, and the Lenders, dated as of June 30, 2023. |
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| 2023-03-06 | 10-K | 10.35 | Executive Incentive Compensation Plan |
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| 2023-03-06 | 10-K | 10.18 | Amendment #2 to Sublease, dated as of January 16, 2023, by and between the |
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| 2022-08-08 | 10-Q | 10.1 | Sublease, dated as of June 8, 2022, by and between the Registrant and Compass Bible Church for premises located at 5 Columbia, Aliso Viejo, California 92656. |
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| 2022-05-05 | 10-Q | 10.3 | Second Amendment to Loan and Security Agreement, by and among the Registrant, Oxford Finance LLC, as collateral agent, and the lenders party thereto, dated as of May 3, 2022. |
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| 2022-05-05 | 10-Q | 10.2 | Lease Addendum, dated as of April 5, 2022, by and between the Registrant and Clifford D. Downs for premises located at 5 Columbia, Aliso Viejo, California 92656. |
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| 2022-05-05 | 10-Q | 10.1 | Sublease, dated as of April 4, 2022, by and between the Registrant and Compass Bible Church for premises located at 5 Columbia, Aliso Viejo, California 92656. |
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| 2022-03-08 | 10-K | 10.28 | Lease, dated as of March 7, 2022, by and between BML Management, LLC, and the Registrant, for premises located at 125 Columbia, Aliso Viejo, California 92656. |
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| 2021-11-10 | 10-Q | 10.3 | 2021 Employee Stock Purchase Plan of the registrant. |
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| 2021-11-10 | 10-Q | 10.2 | 2021 Equity Incentive Plan of the registrant, as amended, and forms of agreement thereunder. |
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