Apple Inc. Clinical Trials
Studies registered on ClinicalTrials.gov (U.S. National Library of Medicine) with the company as lead sponsor or collaborator, newest start first. Values are as registered.
- 2025-12-15: Study NCT07392879; Company role Collaborator; Phase Not applicable; Status Recruiting.
- 2025-06-03: Study NCT06500988; Company role Collaborator; Phase Not applicable; Status Recruiting.
- 2025-02-12: Study NCT06958523; Company role Lead sponsor; Phase Observational; Status Recruiting.
- 2024-09-12: Study NCT06647511; Company role Collaborator; Phase Observational; Status Recruiting.
| Start date | Study | Company role | Phase | Status | Conditions | Enrollment | Completion date |
|---|---|---|---|---|---|---|---|
| 2025-12-15 | NCT07392879 Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients | Collaborator Lead: University of Michigan | Not applicable | Recruiting | Progressive Multiple Sclerosis; Depression | 40 | 2027-04 |
| 2025-06-03 | NCT06500988 Mobile Health Technology-Enabled AFib Management | Collaborator Lead: Johns Hopkins University | Not applicable | Recruiting | Atrial Fibrillation; Behavior | 248 | 2028-06 |
| 2025-02-12 | NCT06958523 Apple Health Study | Lead sponsor | Observational | Recruiting | Mental Health; Sleep; Exercise; Hormones; Metabolic Health; Hearing; Aging; Lifestyle Factors; Functional Capacity; Neurological Conditions; General Health; Wellbeing; Women's Health | 500,000 | 2030-02 |
| 2024-09-12 | NCT06647511 Digital Solutions to Reduce Maternal Morbidity and Mortality in Pregnant Refugee Women | Collaborator Lead: Weill Medical College of Cornell University | Observational | Recruiting | Gestational Hypertension | 75 | 2028-09 |
| 2023-04-20 | NCT05872035 Smartphone Enabled Hearing Study | Lead sponsor | Not applicable | Completed Results posted | Hearing | 118 | 2023-08-17 |
| 2023-04-03 | NCT05238103 Impact of a Corrie Cardiac Rehabilitation Program | Collaborator Lead: Johns Hopkins University | Not applicable | Completed Results posted | Coronary Artery Disease; Myocardial Infarction; Myocardial Ischemia; Coronary Artery Occlusion; Coronary Artery Stenosis Stent; Bypass Graft Occlusion; Valve Heart Disease | 259 | 2024-10-14 |
| 2023-03-15 | NCT05889260 Speech Accessibility Project | Collaborator Lead: University of Illinois at Urbana-Champaign | Observational | Completed | Parkinson Disease; Progressive Supranuclear Palsy; Multiple System Atrophy; Dementia With Lewy Bodies | 485 | 2025-07-31 |
| 2021-09-20 | NCT05058950 An Observational Study Using Multimodal Sensors to Measure Cognitive Health in Adults and Distinguish Mild Cognitive Impairment From Normal Aging | Collaborator Lead: Biogen | Observational | Terminated | Mild Cognitive Impairment; Normal Aging | 22,720 | 2023-09-19 |
| 2021-06-09 | NCT05852951 Cycle and Ovulation Study Expansion | Lead sponsor | Observational | Completed | Menstruation | 698 | 2022-05-23 |
| 2021-04-06 | NCT04912180 Apple Respiratory Study | Lead sponsor | Observational | Terminated | Acute Respiratory Infection; Coronavirus Infection; Influenza | 108 | 2021-06-09 |
| 2021-01-06 | NCT04304495 The Geriatric Acute & Post-acute Care Coordination Program for Fall Prevention in the Emergency Department II | Collaborator Lead: University of Colorado, Denver | Not applicable | Completed | Fall | 197 | 2025-05-02 |
| 2020-12-01 | NCT05008692 Apple-CPET Ted Rogers Understanding Exacerbations of Heart Failure | Collaborator Lead: University Health Network, Toronto | Observational | Unknown | Heart Failure; Heart Failure, Systolic; Heart Failure, Diastolic; Heart Transplantation; Heart Failure，Congestive | 200 | 2023-12 |
| 2020-11-16 | NCT04699812 Atrial Fibrillation Algorithms Clinical Validation Study | Lead sponsor | Not applicable | Completed Results posted | Atrial Fibrillation | 573 | 2021-12-17 |
| 2020-10-30 | NCT04609644 Asthma Digital Study | Collaborator Lead: Elevance Health | Not applicable | Completed | Asthma | 901 | 2023-11-04 |
| 2020-06-01 | NCT04359238 activeDCM - Interventional Clinical Trial of Individualized Activity and Exercise Programs to Improve Outcome in Dilated Cardiomyopathy Guided by Longitudinal Biosensing With Apple Watch | Collaborator Lead: University Hospital Heidelberg | Not applicable | Completed | Cardiomyopathy, Dilated; Heart Failure | 300 | 2025-07-04 |
| 2020-02-25 | NCT04276441 A Study to Investigate if Early Atrial Fibrillation (AF) Diagnosis Reduces Risk of Events Like Stroke in the Real-World | Collaborator Lead: Janssen Scientific Affairs, LLC | Observational | Completed | Atrial Fibrillation | 34,244 | 2025-01-23 |
| 2020-01-07 | NCT04247581 ECG App Algorithms Clinical Validation Study | Lead sponsor | Not applicable | Completed Results posted | Atrial Fibrillation | 546 | 2020-03-20 |
| 2019-11-14 | NCT04198194 Apple Heart & Movement Study | Lead sponsor | Observational | Active not recruiting | Prevention | 500,000 | 2025-02-28 |
| 2019-11-14 | NCT04196595 Apple Women's Health Study | Lead sponsor | Observational | Recruiting | Menstrual Cycle; Ovulation; Menstruation; Polycystic Ovary Syndrome; Infertility; Menopause; Reproduction; Reproductive Health | 500,000 | 2029-11 |
| 2019-11-14 | NCT04172766 Apple Hearing Study | Lead sponsor | Observational | Active not recruiting | Hearing Loss, Noise-Induced; Hearing Loss; Tinnitus | 300,000 | 2029-12 |
| 2018-12-08 | NCT03769207 Evaluation of the Use of Apple Watch Features for Identification of Cardiac Arrhythmias | Lead sponsor | Not applicable | Completed Results posted | Atrial Fibrillation; Arrhythmias, Cardiac; Atrial Flutter | 17 | 2019-08-20 |
| 2018-05-01 | NCT03426280 Activity Therapy After Kidney Transplant | Collaborator Lead: Stanford University | Not applicable | Terminated | Kidney Transplant; Complications | 13 | 2020-01-31 |
| 2018-03-12 | NCT03492554 Electrocardiogram Clinical Validation Study | Lead sponsor | Not applicable | Completed Results posted | Atrial Fibrillation | 602 | 2018-05-14 |
| 2017-11-29 | NCT03335800 Apple Heart Study: Assessment of Wristwatch-Based Photoplethysmography to Identify Cardiac Arrhythmias | Lead sponsor | Not applicable | Completed Results posted | Atrial Fibrillation; Arrhythmias, Cardiac; Atrial Flutter | 419,927 | 2019-02-21 |
| 2016-10-01 | NCT03760796 Myocardial Infarction, COmbined-device, Recovery Enhancement Study | Collaborator Lead: Johns Hopkins University | Not applicable | Completed Results posted | Acute Myocardial Infarction; Coronary Artery Disease; Acute Coronary Syndrome; Myocardial Infarction | 200 | 2019-12-17 |
| 2015-03-15 | NCT03248869 Asthma Mobile Health Application 2.0 | Collaborator Lead: Icahn School of Medicine at Mount Sinai | Not applicable | Completed | Asthma | 7,752 | 2017-03-15 |