ETF:XBI | ETF Holdings | State Street(R) SPDR(R) S&P(R) Biotech ETF

XBI ETF holdings

Weights reproduce the dated portfolio and may not sum to exactly 100% because of cash, derivatives, rounding, liabilities, or other positions. Provenance stays internal.

Snapshot fieldReported value
FundState Street(R) SPDR(R) S&P(R) Biotech ETF
Report date2026-03-31
Reported holdings158
SEC series IDS000010018

Positions 1–100 of 158

TickerIssuerWeightValue (USD)Balance
State Street Global AdvisorsState Street Global Advisors8.009477%595,460,501595,460,501 NS
Apellis Pharmaceuticals IncApellis Pharmaceuticals Inc1.834675%136,397,964.423,390,454 NS
ALKSAlkermes PLC1.451047%107,877,348.83,050,830 NS
MDGLMadrigal Pharmaceuticals Inc1.382936%102,813,695.76196,408 NS
TGTXTG Therapeutics Inc1.349588%100,334,399.223,020,301 NS
INSMInsmed Inc1.336949%99,394,814.4607,845 NS
SRRKScholar Rock Holding Corp1.297342%96,450,199.41,961,965 NS
APGEApogee Therapeutics Inc1.284318%95,481,942.981,134,394 NS
PTGXProtagonist Therapeutics Inc1.244863%92,548,683.4878,071 NS
SMMTSummit Therapeutics Inc1.241085%92,267,854.084,866,448 NS
UTHRUnited Therapeutics Corp1.240525%92,226,179.4155,530 NS
PRAXPraxis Precision Medicines Inc1.236209%91,905,341.88285,252 NS
ARWRArrowhead Pharmaceuticals Inc1.22981%91,429,578.91,458,207 NS
COGTCogent Biosciences Inc1.215671%90,378,407.492,348,101 NS
BBIOBridgebio Pharma Inc1.185467%88,132,956.161,186,816 NS
PTCTPTC Therapeutics Inc1.182233%87,892,537.231,290,071 NS
CYTKCytokinetics Inc1.180398%87,756,067.231,331,453 NS
ALNYAlnylam Pharmaceuticals Inc1.176738%87,484,013.22264,406 NS
EXELExelixis Inc1.170672%87,033,031.352,029,215 NS
Nuvalent IncNuvalent Inc1.166884%86,751,381.6846,768 NS
KYMRKymera Therapeutics Inc1.164332%86,561,631.21,039,280 NS
CGONCG oncology Inc1.162453%86,421,945.61,276,920 NS
NTRANatera Inc1.159229%86,182,290.67430,933 NS
NBIXNeurocrine Biosciences Inc1.15898%86,163,756.56654,044 NS
TWSTTwist Bioscience Corp1.155672%85,917,870.721,808,036 NS
KRYSKrystal Biotech Inc1.154541%85,833,794.64332,277 NS
PCVXVaxcyte Inc1.151121%85,579,468.651,472,715 NS
MIRMMirum Pharmaceuticals Inc1.147502%85,310,435.74923,473 NS
Amicus Therapeutics IncAmicus Therapeutics Inc1.146708%85,251,388.25,895,670 NS
IONSIonis Pharmaceuticals Inc1.144267%85,069,911.541,132,906 NS
TVTXTravere Therapeutics Inc1.144206%85,065,434.322,863,192 NS
Arcellx IncArcellx Inc1.144092%85,056,933.7740,785 NS
REGNRegeneron Pharmaceuticals Inc1.136961%84,526,816109,400 NS
INCYIncyte Corp1.133085%84,238,623.56895,013 NS
CELCCelcuity Inc1.123714%83,541,919.5731,925 NS
Revolution Medicines IncRevolution Medicines Inc1.112889%82,737,188850,768 NS
HALOHalozyme Therapeutics Inc1.107953%82,370,224.071,274,489 NS
RYTMRhythm Pharmaceuticals Inc1.100994%81,852,859.14941,162 NS
BIIBBiogen Inc1.096991%81,555,267.15444,855 NS
ARQTArcutis Biotherapeutics Inc1.089451%80,994,685.83,437,805 NS
ABBVAbbVie Inc1.088563%80,928,681.47372,103 NS
GILDGilead Sciences Inc1.087793%80,871,393.68580,264 NS
CRSPCRISPR Therapeutics AG1.085714%80,716,823.571,696,801 NS
BMRNBioMarin Pharmaceutical Inc1.067274%79,345,910.491,404,601 NS
ROIVRoivant Sciences Ltd1.067186%79,339,364.92,864,237 NS
AMGNAmgen Inc1.062708%79,006,510.1224,546 NS
IBRXImmunityBio Inc1.056859%78,571,671.7510,244,025 NS
BEAMBeam Therapeutics Inc1.041298%77,414,757.583,248,626 NS
VKTXViking Therapeutics Inc1.036975%77,093,410.062,369,189 NS
VERAVera Therapeutics Inc1.034669%76,921,932.421,912,054 NS
MRNAModerna Inc1.034333%76,896,9761,513,720 NS
VRTXVertex Pharmaceuticals Inc1.033563%76,839,710.12172,078 NS
ERASErasca Inc1.030089%76,581,460.924,733,094 NS
ACADACADIA Pharmaceuticals Inc1.021807%75,965,700.33,412,655 NS
SRPTSarepta Therapeutics Inc0.894767%66,520,972.83,057,030 NS
AGIOAgios Pharmaceuticals Inc0.878382%65,302,860.921,930,324 NS
RAREUltragenyx Pharmaceutical Inc0.875777%65,109,185.153,107,837 NS
IRONDisc Medicine Inc0.870412%64,710,349.121,012,048 NS
IMNMImmunome Inc0.863334%64,184,119.742,934,802 NS
IMVTImmunovant Inc0.857529%63,752,555.522,566,528 NS
BCRXBioCryst Pharmaceuticals Inc0.852197%63,356,114.086,655,054 NS
VCYTVeracyte Inc0.848172%63,056,905.011,957,681 NS
DYNDyne Therapeutics Inc0.838291%62,322,310.123,437,524 NS
Catalyst Pharmaceuticals IncCatalyst Pharmaceuticals Inc0.755441%56,162,909.922,268,292 NS
SNDXSyndax Pharmaceuticals Inc0.736261%54,736,941.762,343,191 NS
DNLIDenali Therapeutics Inc0.731088%54,352,396.82,830,854 NS
IDYAIdeaya Biosciences Inc0.729969%54,269,150.321,628,726 NS
SYRESpyre Therapeutics Inc0.725654%53,948,404.641,069,556 NS
GRALGRAIL Inc0.723848%53,814,125.61,041,295 NS
VRDNViridian Therapeutics Inc0.701688%52,166,656.922,667,007 NS
RXRXRecursion Pharmaceuticals Inc0.690957%51,368,808.7716,732,511 NS
KODKodiak Sciences Inc0.689211%51,239,036.121,344,151 NS
Soleno Therapeutics IncSoleno Therapeutics Inc0.673738%50,088,691.441,496,078 NS
DNTHDianthus Therapeutics Inc0.662236%49,233,598.16586,673 NS
NTLAIntellia Therapeutics Inc0.647227%48,117,729.063,753,333 NS
MLYSMineralys Therapeutics Inc0.646145%48,037,288.321,773,248 NS
RCUSArcus Biosciences Inc0.628542%46,728,640.82,163,363 NS
ARDXArdelyx Inc0.617531%45,910,043.527,664,448 NS
ADMAADMA Biologics Inc0.595794%44,293,988.924,916,092 NS
NRIXNurix Therapeutics Inc0.585828%43,553,093.52,809,877 NS
TNGXTango Therapeutics Inc0.555067%41,266,185.321,972,571 NS
CLDXCelldex Therapeutics Inc0.521586%38,777,065.61,222,480 NS
NVAXNovavax Inc0.511069%37,995,200.14,667,715 NS
ORKAOruka Therapeutics Inc0.502104%37,328,668.65761,033 NS
OLMAOlema Pharmaceuticals Inc0.495742%36,855,715.892,471,879 NS
STOKStoke Therapeutics Inc0.493001%36,651,880.321,125,672 NS
VCELVericel Corp0.483019%35,909,826.841,116,252 NS
CAPRCapricor Therapeutics Inc0.479196%35,625,577.61,171,894 NS
PVLAPalvella Therapeutics Inc0.459792%34,183,018.8274,232 NS
BHVNBiohaven Ltd0.437504%32,526,009.723,844,682 NS
GLUEMonte Rosa Therapeutics Inc0.435173%32,352,724.951,966,731 NS
CRVSCorvus Pharmaceuticals Inc0.416569%30,969,632.542,116,858 NS
IOVAIovance Biotherapeutics Inc0.384305%28,570,954.238,139,873 NS
ANABAnaptysBio Inc0.382076%28,405,225.5512,175 NS
RLAYRelay Therapeutics Inc0.378976%28,174,808.052,831,639 NS
QUREuniQure NV0.373296%27,752,522.71,697,402 NS
ORICORIC Pharmaceuticals Inc0.370075%27,513,057.042,171,512 NS
MNKDMannKind Corp0.360315%26,787,459.6510,933,657 NS
CDNACareDx Inc0.345689%25,700,073.841,480,419 NS
TSHATaysha Gene Therapies Inc0.339042%25,205,932.175,638,911 NS

Research interface only. Not investment advice. Prices are a checked-in snapshot, not live quotes.