GNOM additions & removals
Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.
Additions
| Ticker | Issuer | Observed date | Change |
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| Qiagen N.V. | Qiagen N.V. | 2026-02-28 | Added / first present |
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| Atrium Therapeutics Inc | Atrium Therapeutics Inc | 2026-02-28 | Added / first present |
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| EDITAS MEDICINE, INC. | EDITAS MEDICINE, INC. | 2025-11-30 | Added / first present |
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| STANDARD BIOTOOLS INC. | STANDARD BIOTOOLS INC. | 2025-11-30 | Added / first present |
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| MESA LABORATORIES, INC. | MESA LABORATORIES, INC. | 2025-11-30 | Added / first present |
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| Caribou Biosciences Inc | Caribou Biosciences Inc | 2025-11-30 | Added / first present |
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| BRISTOL-MYERS SQUIBB CO | BRISTOL-MYERS SQUIBB CO | 2025-05-31 | Added / first present |
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| ELI LILLY AND COMPANY | ELI LILLY AND COMPANY | 2025-05-31 | Added / first present |
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| GUARDANT HEALTH, INC. | GUARDANT HEALTH, INC. | 2025-05-31 | Added / first present |
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| Twist Bioscience Corp | Twist Bioscience Corp | 2025-05-31 | Added / first present |
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| Personalis Inc | Personalis Inc | 2025-05-31 | Added / first present |
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| Stoke Therapeutics Inc | Stoke Therapeutics Inc | 2025-05-31 | Added / first present |
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| Arcturus Therapeutics Holdings Inc | Arcturus Therapeutics Holdings Inc | 2025-05-31 | Added / first present |
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| WAVE Life Sciences Ltd | WAVE Life Sciences Ltd | 2025-05-31 | Added / first present |
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| CureVac N.V. | CureVac N.V. | 2025-05-31 | Added / first present |
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| Prime Medicine Inc | Prime Medicine Inc | 2025-05-31 | Added / first present |
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| GeneDx Holdings Corp | GeneDx Holdings Corp | 2025-05-31 | Added / first present |
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| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2025-05-31 | Added / first present |
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| CARGO Therapeutics Inc | CARGO Therapeutics Inc | 2025-05-31 | Added / first present |
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| Qiagen N.V. | Qiagen N.V. | 2025-02-28 | Added / first present |
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| SANGAMO THERAPEUTICS, INC. | SANGAMO THERAPEUTICS, INC. | 2024-11-30 | Added / first present |
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| Maravai LifeSciences Holdings Inc | Maravai LifeSciences Holdings Inc | 2024-11-30 | Added / first present |
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| Grail Inc | Grail Inc | 2024-08-31 | Added / first present |
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| BNYREPOS | BNYREPOS | 2024-05-31 | Added / first present |
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| Qiagen N.V. | Qiagen N.V. | 2024-02-29 | Added / first present |
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| DAIW | DAIWA CAPITAL MARKETS AMERICA INC | 2024-02-29 | Added / first present |
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| HSBU | HSBC SECURITIES (USA) INC | 2024-02-29 | Added / first present |
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| BOAS | BOFA SECURITIES INC | 2024-02-29 | Added / first present |
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| DEUS | DEUTSCHE BANK SECURITIES INC | 2024-02-29 | Added / first present |
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| NMRA | NOMURA SECURITIES INTERNATIONAL INC | 2024-02-29 | Added / first present |
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| Vir Biotechnology Inc | Vir Biotechnology Inc | 2023-11-30 | Added / first present |
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| Avidity Biosciences Inc | Avidity Biosciences Inc | 2023-11-30 | Added / first present |
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| Legend Biotech Corp | Legend Biotech Corp | 2023-11-30 | Added / first present |
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| Sana Biotechnology Inc | Sana Biotechnology Inc | 2023-11-30 | Added / first present |
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| Lyell Immunopharma Inc | Lyell Immunopharma Inc | 2023-11-30 | Added / first present |
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| Bionano Genomics Inc | Bionano Genomics Inc | 2023-08-31 | Added / first present |
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| Poseida Therapeutics Inc | Poseida Therapeutics Inc | 2023-05-31 | Added / first present |
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| N/A | N/A | 2023-02-28 | Added / first present |
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| 10X Genomics Inc | 10X Genomics Inc | 2022-11-30 | Added / first present |
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| BIO-TECHNE CORPORATION | BIO-TECHNE CORPORATION | 2022-11-30 | Added / first present |
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| Stoke Therapeutics Inc | Stoke Therapeutics Inc | 2022-05-31 | Added / first present |
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| Fulgent Genetics Inc | Fulgent Genetics Inc | 2022-05-31 | Added / first present |
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| Bionano Genomics Inc | Bionano Genomics Inc | 2022-05-31 | Added / first present |
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| Beam Therapeutics Inc | Beam Therapeutics Inc | 2022-05-31 | Added / first present |
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| Verve Therapeutics Inc | Verve Therapeutics Inc | 2022-05-31 | Added / first present |
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| MODERNA, INC. | MODERNA, INC. | 2021-11-30 | Added / first present |
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| BioNTech SE | BioNTech SE | 2021-11-30 | Added / first present |
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| REPO | BNP Paribas Securities Corp Repo | 2021-11-30 | Added / first present |
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| Caribou Biosciences Inc | Caribou Biosciences Inc | 2021-11-30 | Added / first present |
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| 2Seventy Bio Inc | 2Seventy Bio Inc | 2021-11-30 | Added / first present |
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| Fidelity Money Market Government Portfolio | Fidelity Money Market Government Portfolio | 2021-05-31 | Added / first present |
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| ProQR Therapeutics NV | ProQR Therapeutics NV | 2021-05-31 | Added / first present |
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| Cellectis SA | Cellectis SA | 2020-11-30 | Added / first present |
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| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2020-05-31 | Added / first present |
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| CAREDX, INC. | CAREDX, INC. | 2020-05-31 | Added / first present |
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| LUMINEX CORPORATION | LUMINEX CORPORATION | 2020-05-31 | Added / first present |
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| MYRIAD GENETICS, INC. | MYRIAD GENETICS, INC. | 2020-05-31 | Added / first present |
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| Precision BioSciences Inc | Precision BioSciences Inc | 2020-05-31 | Added / first present |
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Removals
| Ticker | Issuer | Observed date | Change |
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| CureVac N.V. | CureVac N.V. | 2026-02-28 | Removed / first absent |
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| CARGO Therapeutics Inc | CARGO Therapeutics Inc | 2025-08-31 | Removed / first absent |
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| Qiagen N.V. | Qiagen N.V. | 2026-02-28 | Removed / first absent |
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| Grail Inc | Grail Inc | 2024-11-30 | Removed / first absent |
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| Qiagen N.V. | Qiagen N.V. | 2025-02-28 | Removed / first absent |
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| DAIW | DAIWA CAPITAL MARKETS AMERICA INC | 2024-05-31 | Removed / first absent |
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| HSBU | HSBC SECURITIES (USA) INC | 2024-05-31 | Removed / first absent |
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| BOAS | BOFA SECURITIES INC | 2024-05-31 | Removed / first absent |
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| DEUS | DEUTSCHE BANK SECURITIES INC | 2024-05-31 | Removed / first absent |
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| NMRA | NOMURA SECURITIES INTERNATIONAL INC | 2024-05-31 | Removed / first absent |
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| Lyell Immunopharma Inc | Lyell Immunopharma Inc | 2025-05-31 | Removed / first absent |
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| Bionano Genomics Inc | Bionano Genomics Inc | 2023-11-30 | Removed / first absent |
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| Poseida Therapeutics Inc | Poseida Therapeutics Inc | 2025-02-28 | Removed / first absent |
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| N/A | N/A | 2025-05-31 | Removed / first absent |
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| Stoke Therapeutics Inc | Stoke Therapeutics Inc | 2023-11-30 | Removed / first absent |
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| Bionano Genomics Inc | Bionano Genomics Inc | 2023-08-31 | Removed / first absent |
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| Verve Therapeutics Inc | Verve Therapeutics Inc | 2025-08-31 | Removed / first absent |
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| REPO | BNP Paribas Securities Corp Repo | 2022-08-31 | Removed / first absent |
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| Caribou Biosciences Inc | Caribou Biosciences Inc | 2025-05-31 | Removed / first absent |
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| 2Seventy Bio Inc | 2Seventy Bio Inc | 2025-05-31 | Removed / first absent |
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| Fidelity Money Market Government Portfolio | Fidelity Money Market Government Portfolio | 2023-08-31 | Removed / first absent |
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| ProQR Therapeutics NV | ProQR Therapeutics NV | 2022-05-31 | Removed / first absent |
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| Cellectis SA | Cellectis SA | 2022-11-30 | Removed / first absent |
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| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2025-11-30 | Removed / first absent |
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| LUMINEX CORPORATION | LUMINEX CORPORATION | 2021-08-31 | Removed / first absent |
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| Precision BioSciences Inc | Precision BioSciences Inc | 2022-05-31 | Removed / first absent |
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| BLUEBIRD BIO, INC. | BLUEBIRD BIO, INC. | 2024-11-30 | Removed / first absent |
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| Blueprint Medicines Corp | Blueprint Medicines Corp | 2021-11-30 | Removed / first absent |
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| PTC THERAPEUTICS, INC. | PTC THERAPEUTICS, INC. | 2021-05-31 | Removed / first absent |
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| Audentes Therapeutics Inc | Audentes Therapeutics Inc | 2020-02-29 | Removed / first absent |
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| Editas Medicine Inc | Editas Medicine Inc | 2025-05-31 | Removed / first absent |
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| INVITAE CORPORATION | INVITAE CORPORATION | 2023-11-30 | Removed / first absent |
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| SANGAMO THERAPEUTICS, INC. | SANGAMO THERAPEUTICS, INC. | 2023-11-30 | Removed / first absent |
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| DICERNA PHARMACEUTICALS, INC. | DICERNA PHARMACEUTICALS, INC. | 2022-02-28 | Removed / first absent |
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| NanoString Technologies Inc | NanoString Technologies Inc | 2023-11-30 | Removed / first absent |
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| ZIOPHARM ONCOLOGY, INC. | ZIOPHARM ONCOLOGY, INC. | 2022-05-31 | Removed / first absent |
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| Voyager Therapeutics Inc | Voyager Therapeutics Inc | 2021-11-30 | Removed / first absent |
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| Solid Biosciences Inc | Solid Biosciences Inc | 2020-05-31 | Removed / first absent |
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| FLUIDIGM CORPORATION | FLUIDIGM CORPORATION | 2020-05-31 | Removed / first absent |
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| SORRENTO THERAPEUTICS, INC. | SORRENTO THERAPEUTICS, INC. | 2023-02-28 | Removed / first absent |
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| Spark Therapeutics Inc | Spark Therapeutics Inc | 2020-02-29 | Removed / first absent |
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| Homology Medicines Inc | Homology Medicines Inc | 2022-05-31 | Removed / first absent |
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| Qiagen N.V. | Qiagen N.V. | 2024-02-29 | Removed / first absent |
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| ADVERUM BIOTECHNOLOGIES, INC. | ADVERUM BIOTECHNOLOGIES, INC. | 2022-05-31 | Removed / first absent |
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| WAVE Life Sciences Ltd | WAVE Life Sciences Ltd | 2022-05-31 | Removed / first absent |
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| ProQR Therapeutics NV | ProQR Therapeutics NV | 2020-11-30 | Removed / first absent |
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