ETF:XPH | Additions & Removals | State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF

XPH additions & removals

Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.

Additions

TickerIssuerObserved dateChange
Fulcrum Therapeutics IncFulcrum Therapeutics Inc2026-03-31Added / first present
Alto Neuroscience IncAlto Neuroscience Inc2026-03-31Added / first present
BioAge Labs IncBioAge Labs Inc2026-03-31Added / first present
LB Pharmaceuticals IncLB Pharmaceuticals Inc2026-03-31Added / first present
Indivior Pharmaceuticals IncIndivior Pharmaceuticals Inc2026-03-31Added / first present
Definium Therapeutics IncDefinium Therapeutics Inc2026-03-31Added / first present
Omeros CorpOmeros Corp2025-12-31Added / first present
Aquestive Therapeutics IncAquestive Therapeutics Inc2025-12-31Added / first present
Ventyx Biosciences IncVentyx Biosciences Inc2025-12-31Added / first present
Rapport Therapeutics IncRapport Therapeutics Inc2025-12-31Added / first present
Septerna IncSepterna Inc2025-12-31Added / first present
Alumis IncAlumis Inc2025-12-31Added / first present
MBX Biosciences IncMBX Biosciences Inc2025-12-31Added / first present
Maze Therapeutics IncMaze Therapeutics Inc2025-12-31Added / first present
Esperion Therapeutics IncEsperion Therapeutics Inc2025-09-30Added / first present
Crinetics Pharmaceuticals IncCrinetics Pharmaceuticals Inc2025-09-30Added / first present
ALT5 Sigma CorpALT5 Sigma Corp2025-09-30Added / first present
Phathom Pharmaceuticals IncPhathom Pharmaceuticals Inc2025-09-30Added / first present
Terns Pharmaceuticals IncTerns Pharmaceuticals Inc2025-09-30Added / first present
Amylyx Pharmaceuticals IncAmylyx Pharmaceuticals Inc2025-09-30Added / first present
Nektar TherapeuticsNektar Therapeutics2025-09-30Added / first present
Trevi Therapeutics IncTrevi Therapeutics Inc2025-06-30Added / first present
LENZ Therapeutics IncLENZ Therapeutics Inc2025-06-30Added / first present
Omeros CorpOmeros Corp2025-03-31Added / first present
Esperion Therapeutics IncEsperion Therapeutics Inc2024-12-31Added / first present
CorMedix IncCorMedix Inc2024-12-31Added / first present
Phibro Animal Health CorpPhibro Animal Health Corp2024-12-31Added / first present
Zevra Therapeutics IncZevra Therapeutics Inc2024-12-31Added / first present
Phathom Pharmaceuticals IncPhathom Pharmaceuticals Inc2024-09-30Added / first present
Neumora Therapeutics IncNeumora Therapeutics Inc2024-09-30Added / first present
Harrow IncHarrow Inc2024-06-30Added / first present
Nuvation Bio IncNuvation Bio Inc2024-06-30Added / first present
Edgewise Therapeutics IncEdgewise Therapeutics Inc2024-06-30Added / first present
Mind Medicine MindMed IncMind Medicine MindMed Inc2024-06-30Added / first present
Enliven Therapeutics IncEnliven Therapeutics Inc2024-06-30Added / first present
Ocular Therapeutix IncOcular Therapeutix Inc2024-03-31Added / first present
Liquidia CorpLiquidia Corp2024-03-31Added / first present
Fulcrum Therapeutics IncFulcrum Therapeutics Inc2024-03-31Added / first present
Marinus Pharmaceuticals IncMarinus Pharmaceuticals Inc2024-03-31Added / first present
EyePoint Pharmaceuticals IncEyePoint Pharmaceuticals Inc2024-03-31Added / first present
Longboard Pharmaceuticals IncLongboard Pharmaceuticals Inc2024-03-31Added / first present
Xeris Biopharma Holdings IncXeris Biopharma Holdings Inc2024-03-31Added / first present
Amneal Pharmaceuticals IncAmneal Pharmaceuticals Inc2023-12-31Added / first present
Cassava Sciences IncCassava Sciences Inc2023-12-31Added / first present
Evolus IncEvolus Inc2023-09-30Added / first present
Phathom Pharmaceuticals IncPhathom Pharmaceuticals Inc2023-09-30Added / first present
Tarsus Pharmaceuticals IncTarsus Pharmaceuticals Inc2023-09-30Added / first present
Harrow Health IncHarrow Health Inc2023-06-30Added / first present
Cymabay Therapeutics IncCymabay Therapeutics Inc2023-03-31Added / first present
Ocular Therapeutix IncOcular Therapeutix Inc2023-03-31Added / first present
Ligand Pharmaceuticals IncLigand Pharmaceuticals Inc2022-12-31Added / first present
Provention Bio IncProvention Bio Inc2022-12-31Added / first present
DICE Therapeutics IncDICE Therapeutics Inc2022-12-31Added / first present
Esperion Therapeutics IncEsperion Therapeutics Inc2022-09-30Added / first present
Pliant Therapeutics IncPliant Therapeutics Inc2022-09-30Added / first present
Ventyx Biosciences IncVentyx Biosciences Inc2022-09-30Added / first present
CinCor Pharma IncCinCor Pharma Inc2022-09-30Added / first present
Amylyx Pharmaceuticals IncAmylyx Pharmaceuticals Inc2022-09-30Added / first present
Evolus IncEvolus Inc2022-06-30Added / first present
SIGA Technologies IncSIGA Technologies Inc2022-06-30Added / first present
Relmada Therapeutics IncRelmada Therapeutics Inc2022-03-31Added / first present
Esperion Therapeutics IncEsperion Therapeutics Inc2021-12-31Added / first present
ANI Pharmaceuticals IncANI Pharmaceuticals Inc2021-12-31Added / first present
Harmony Biosciences Holdings IncHarmony Biosciences Holdings Inc2021-12-31Added / first present
Athira Pharma IncAthira Pharma Inc2021-12-31Added / first present
Atea Pharmaceuticals IncAtea Pharmaceuticals Inc2021-12-31Added / first present
Fulcrum Therapeutics IncFulcrum Therapeutics Inc2021-09-30Added / first present
Antares Pharma IncAntares Pharma Inc2021-06-30Added / first present
Nuvation Bio IncNuvation Bio Inc2021-06-30Added / first present
Organon & CoOrganon & Co2021-06-30Added / first present
TherapeuticsMD IncTherapeuticsMD Inc2021-03-31Added / first present
CorMedix IncCorMedix Inc2021-03-31Added / first present
Aclaris Therapeutics IncAclaris Therapeutics Inc2021-03-31Added / first present
Odonate Therapeutics IncOdonate Therapeutics Inc2021-03-31Added / first present
Durect CorpDurect Corp2021-03-31Added / first present
Cassava Sciences IncCassava Sciences Inc2021-03-31Added / first present
Atea Pharmaceuticals IncAtea Pharmaceuticals Inc2021-03-31Added / first present
Zomedica CorpZomedica Corp2021-03-31Added / first present
NGM Biopharmaceuticals IncNGM Biopharmaceuticals Inc2020-12-31Added / first present
Marinus Pharmaceuticals IncMarinus Pharmaceuticals Inc2020-12-31Added / first present
Viatris IncViatris Inc2020-12-31Added / first present
Cymabay Therapeutics IncCymabay Therapeutics Inc2020-09-30Added / first present
Ocular Therapeutix IncOcular Therapeutix Inc2020-09-30Added / first present
Amneal Pharmaceuticals IncAmneal Pharmaceuticals Inc2020-06-30Added / first present
Provention Bio IncProvention Bio Inc2020-06-30Added / first present
Relmada Therapeutics IncRelmada Therapeutics Inc2020-06-30Added / first present
Phathom Pharmaceuticals IncPhathom Pharmaceuticals Inc2020-06-30Added / first present
Arvinas Holding Co LLCArvinas Holding Co LLC2019-12-31Added / first present
BioDelivery Sciences International IncBioDelivery Sciences International Inc2019-12-31Added / first present

Removals

TickerIssuerObserved dateChange
Ventyx Biosciences IncVentyx Biosciences Inc2026-03-31Removed / first absent
ALT5 Sigma CorpALT5 Sigma Corp2025-12-31Removed / first absent
LENZ Therapeutics IncLENZ Therapeutics Inc2026-03-31Removed / first absent
Omeros CorpOmeros Corp2025-06-30Removed / first absent
Esperion Therapeutics IncEsperion Therapeutics Inc2025-06-30Removed / first absent
Phathom Pharmaceuticals IncPhathom Pharmaceuticals Inc2025-03-31Removed / first absent
Neumora Therapeutics IncNeumora Therapeutics Inc2025-03-31Removed / first absent
Mind Medicine MindMed IncMind Medicine MindMed Inc2026-03-31Removed / first absent
Fulcrum Therapeutics IncFulcrum Therapeutics Inc2024-12-31Removed / first absent
Marinus Pharmaceuticals IncMarinus Pharmaceuticals Inc2024-06-30Removed / first absent
Longboard Pharmaceuticals IncLongboard Pharmaceuticals Inc2024-12-31Removed / first absent
Cassava Sciences IncCassava Sciences Inc2024-03-31Removed / first absent
Evolus IncEvolus Inc2026-03-31Removed / first absent
Phathom Pharmaceuticals IncPhathom Pharmaceuticals Inc2023-12-31Removed / first absent
Harrow Health IncHarrow Health Inc2023-12-31Removed / first absent
Cymabay Therapeutics IncCymabay Therapeutics Inc2024-03-31Removed / first absent
Ocular Therapeutix IncOcular Therapeutix Inc2023-12-31Removed / first absent
Provention Bio IncProvention Bio Inc2023-06-30Removed / first absent
DICE Therapeutics IncDICE Therapeutics Inc2023-09-30Removed / first absent
Esperion Therapeutics IncEsperion Therapeutics Inc2023-06-30Removed / first absent
Pliant Therapeutics IncPliant Therapeutics Inc2025-03-31Removed / first absent
Ventyx Biosciences IncVentyx Biosciences Inc2023-12-31Removed / first absent
CinCor Pharma IncCinCor Pharma Inc2022-12-31Removed / first absent
Amylyx Pharmaceuticals IncAmylyx Pharmaceuticals Inc2024-06-30Removed / first absent
Evolus IncEvolus Inc2022-12-31Removed / first absent
SIGA Technologies IncSIGA Technologies Inc2023-03-31Removed / first absent
Relmada Therapeutics IncRelmada Therapeutics Inc2022-12-31Removed / first absent
Esperion Therapeutics IncEsperion Therapeutics Inc2022-03-31Removed / first absent
Athira Pharma IncAthira Pharma Inc2022-09-30Removed / first absent
Atea Pharmaceuticals IncAtea Pharmaceuticals Inc2023-03-31Removed / first absent
Fulcrum Therapeutics IncFulcrum Therapeutics Inc2022-06-30Removed / first absent
Antares Pharma IncAntares Pharma Inc2022-06-30Removed / first absent
Nuvation Bio IncNuvation Bio Inc2022-12-31Removed / first absent
TherapeuticsMD IncTherapeuticsMD Inc2021-09-30Removed / first absent
CorMedix IncCorMedix Inc2021-06-30Removed / first absent
Aclaris Therapeutics IncAclaris Therapeutics Inc2023-12-31Removed / first absent
Odonate Therapeutics IncOdonate Therapeutics Inc2021-06-30Removed / first absent
Durect CorpDurect Corp2021-12-31Removed / first absent
Cassava Sciences IncCassava Sciences Inc2024-12-31Removed / first absent
Atea Pharmaceuticals IncAtea Pharmaceuticals Inc2021-06-30Removed / first absent
Zomedica CorpZomedica Corp2021-09-30Removed / first absent
NGM Biopharmaceuticals IncNGM Biopharmaceuticals Inc2022-12-31Removed / first absent
Marinus Pharmaceuticals IncMarinus Pharmaceuticals Inc2022-03-31Removed / first absent
Cymabay Therapeutics IncCymabay Therapeutics Inc2021-03-31Removed / first absent
Ocular Therapeutix IncOcular Therapeutix Inc2022-06-30Removed / first absent
Amneal Pharmaceuticals IncAmneal Pharmaceuticals Inc2022-09-30Removed / first absent
Provention Bio IncProvention Bio Inc2022-06-30Removed / first absent
Relmada Therapeutics IncRelmada Therapeutics Inc2021-12-31Removed / first absent
Phathom Pharmaceuticals IncPhathom Pharmaceuticals Inc2021-12-31Removed / first absent
BioDelivery Sciences International IncBioDelivery Sciences International Inc2021-12-31Removed / first absent
Nektar TherapeuticsNektar Therapeutics2023-03-31Removed / first absent
Aerie Pharmaceuticals IncAerie Pharmaceuticals Inc2022-06-30Removed / first absent
Reata Pharmaceuticals IncReata Pharmaceuticals Inc2023-09-30Removed / first absent
Tricida IncTricida Inc2020-09-30Removed / first absent
MyoKardia IncMyoKardia Inc2020-12-31Removed / first absent
Zogenix IncZogenix Inc2022-03-31Removed / first absent
TherapeuticsMD IncTherapeuticsMD Inc2020-06-30Removed / first absent
Omeros CorpOmeros Corp2022-06-30Removed / first absent
Cara Therapeutics IncCara Therapeutics Inc2023-06-30Removed / first absent
Revance Therapeutics IncRevance Therapeutics Inc2024-06-30Removed / first absent
Intersect ENT IncIntersect ENT Inc2020-12-31Removed / first absent
Intra-Cellular Therapies IncIntra-Cellular Therapies Inc2025-06-30Removed / first absent
Cymabay Therapeutics IncCymabay Therapeutics Inc2019-12-31Removed / first absent
State Street Global AdvisorsState Street Global Advisors2024-09-30Removed / first absent
ANI Pharmaceuticals IncANI Pharmaceuticals Inc2020-06-30Removed / first absent
Phibro Animal Health CorpPhibro Animal Health Corp2022-12-31Removed / first absent
Catalent IncCatalent Inc2024-12-31Removed / first absent

Research interface only. Not investment advice. Prices are a checked-in snapshot, not live quotes.