XHE additions & removals
Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.
Additions
| Ticker | Issuer | Observed date | Change |
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| Bioventus Inc | Bioventus Inc | 2026-03-31 | Added / first present |
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| Medline Inc | Medline Inc | 2026-03-31 | Added / first present |
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| Strive Inc | Strive Inc | 2026-03-31 | Added / first present |
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| Tactile Systems Technology Inc | Tactile Systems Technology Inc | 2025-12-31 | Added / first present |
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| ClearPoint Neuro Inc | ClearPoint Neuro Inc | 2025-12-31 | Added / first present |
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| Senseonics Holdings Inc | Senseonics Holdings Inc | 2025-12-31 | Added / first present |
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| iRadimed Corp | iRadimed Corp | 2025-09-30 | Added / first present |
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| Beta Bionics Inc | Beta Bionics Inc | 2025-09-30 | Added / first present |
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| AngioDynamics Inc | AngioDynamics Inc | 2025-06-30 | Added / first present |
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| Delcath Systems Inc | Delcath Systems Inc | 2025-06-30 | Added / first present |
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| CONTRA PARAGON 28 INC | CONTRA PARAGON 28 INC | 2025-06-30 | Added / first present |
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| Senseonics Holdings Inc | Senseonics Holdings Inc | 2025-03-31 | Added / first present |
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| Butterfly Network Inc | Butterfly Network Inc | 2024-12-31 | Added / first present |
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| Bioventus Inc | Bioventus Inc | 2024-12-31 | Added / first present |
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| Paragon 28 Inc | Paragon 28 Inc | 2024-12-31 | Added / first present |
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| Axogen Inc | Axogen Inc | 2024-09-30 | Added / first present |
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| Solventum Corp | Solventum Corp | 2024-06-30 | Added / first present |
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| Zimvie Inc | Zimvie Inc | 2024-03-31 | Added / first present |
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| Cooper Cos Inc/The | Cooper Cos Inc/The | 2024-03-31 | Added / first present |
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| Surmodics Inc | Surmodics Inc | 2023-09-30 | Added / first present |
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| RxSight Inc | RxSight Inc | 2023-09-30 | Added / first present |
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| Tactile Systems Technology Inc | Tactile Systems Technology Inc | 2023-06-30 | Added / first present |
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| OraSure Technologies Inc | OraSure Technologies Inc | 2023-03-31 | Added / first present |
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| Pulmonx Corp | Pulmonx Corp | 2023-03-31 | Added / first present |
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| GE HealthCare Technologies Inc | GE HealthCare Technologies Inc | 2023-03-31 | Added / first present |
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| Inspire Medical Systems Inc | Inspire Medical Systems Inc | 2022-09-30 | Added / first present |
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| Treace Medical Concepts Inc | Treace Medical Concepts Inc | 2022-09-30 | Added / first present |
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| PROCEPT BioRobotics Corp | PROCEPT BioRobotics Corp | 2022-09-30 | Added / first present |
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| Paragon 28 Inc | Paragon 28 Inc | 2022-09-30 | Added / first present |
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| Omnicell Inc | Omnicell Inc | 2022-06-30 | Added / first present |
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| UFP Technologies Inc | UFP Technologies Inc | 2022-06-30 | Added / first present |
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| Embecta Corp | Embecta Corp | 2022-06-30 | Added / first present |
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| Enovis Corp | Enovis Corp | 2022-06-30 | Added / first present |
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| QuidelOrtho Corp | QuidelOrtho Corp | 2022-06-30 | Added / first present |
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| Zimvie Inc | Zimvie Inc | 2022-03-31 | Added / first present |
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| Accuray Inc | Accuray Inc | 2021-12-31 | Added / first present |
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| SeaSpine Holdings Corp | SeaSpine Holdings Corp | 2021-12-31 | Added / first present |
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| Figs Inc | Figs Inc | 2021-12-31 | Added / first present |
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| PAVmed Inc | PAVmed Inc | 2021-09-30 | Added / first present |
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| Zomedica Corp | Zomedica Corp | 2021-09-30 | Added / first present |
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| Butterfly Network Inc | Butterfly Network Inc | 2021-09-30 | Added / first present |
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| Asensus Surgical Inc | Asensus Surgical Inc | 2021-09-30 | Added / first present |
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| Senseonics Holdings Inc | Senseonics Holdings Inc | 2021-03-31 | Added / first present |
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| TransMedics Group Inc | TransMedics Group Inc | 2021-03-31 | Added / first present |
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| Aspira Women's Health Inc | Aspira Women's Health Inc | 2021-03-31 | Added / first present |
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| Outset Medical Inc | Outset Medical Inc | 2021-03-31 | Added / first present |
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| Pulmonx Corp | Pulmonx Corp | 2021-03-31 | Added / first present |
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| Eargo Inc | Eargo Inc | 2021-03-31 | Added / first present |
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| Intersect ENT Inc | Intersect ENT Inc | 2020-12-31 | Added / first present |
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| Cutera Inc | Cutera Inc | 2020-12-31 | Added / first present |
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| BioLife Solutions Inc | BioLife Solutions Inc | 2020-12-31 | Added / first present |
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| ViewRay Inc | ViewRay Inc | 2020-12-31 | Added / first present |
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| Alphatec Holdings Inc | Alphatec Holdings Inc | 2020-12-31 | Added / first present |
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| Inari Medical Inc | Inari Medical Inc | 2020-12-31 | Added / first present |
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| SI-BONE Inc | SI-BONE Inc | 2020-09-30 | Added / first present |
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| Vapotherm Inc | Vapotherm Inc | 2020-09-30 | Added / first present |
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| Shockwave Medical Inc | Shockwave Medical Inc | 2020-09-30 | Added / first present |
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| Envista Holdings Corp | Envista Holdings Corp | 2020-06-30 | Added / first present |
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| Silk Road Medical Inc | Silk Road Medical Inc | 2020-06-30 | Added / first present |
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| OrthoPediatrics Corp | OrthoPediatrics Corp | 2020-06-30 | Added / first present |
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| GenMark Diagnostics Inc | GenMark Diagnostics Inc | 2020-06-30 | Added / first present |
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| Axonics Modulation Technologies Inc | Axonics Modulation Technologies Inc | 2020-06-30 | Added / first present |
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| SmileDirectClub Inc | SmileDirectClub Inc | 2020-06-30 | Added / first present |
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| State Street Global Advisors | State Street Global Advisors | 2019-12-31 | Added / first present |
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Removals
| Ticker | Issuer | Observed date | Change |
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| Senseonics Holdings Inc | Senseonics Holdings Inc | 2026-03-31 | Removed / first absent |
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| Delcath Systems Inc | Delcath Systems Inc | 2025-09-30 | Removed / first absent |
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| Senseonics Holdings Inc | Senseonics Holdings Inc | 2025-12-31 | Removed / first absent |
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| Bioventus Inc | Bioventus Inc | 2025-06-30 | Removed / first absent |
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| Paragon 28 Inc | Paragon 28 Inc | 2025-06-30 | Removed / first absent |
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| Zimvie Inc | Zimvie Inc | 2025-06-30 | Removed / first absent |
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| Surmodics Inc | Surmodics Inc | 2025-12-31 | Removed / first absent |
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| RxSight Inc | RxSight Inc | 2026-03-31 | Removed / first absent |
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| Tactile Systems Technology Inc | Tactile Systems Technology Inc | 2025-06-30 | Removed / first absent |
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| OraSure Technologies Inc | OraSure Technologies Inc | 2024-12-31 | Removed / first absent |
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| Pulmonx Corp | Pulmonx Corp | 2024-06-30 | Removed / first absent |
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| Treace Medical Concepts Inc | Treace Medical Concepts Inc | 2024-06-30 | Removed / first absent |
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| Paragon 28 Inc | Paragon 28 Inc | 2024-06-30 | Removed / first absent |
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| Zimvie Inc | Zimvie Inc | 2022-12-31 | Removed / first absent |
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| Accuray Inc | Accuray Inc | 2022-06-30 | Removed / first absent |
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| SeaSpine Holdings Corp | SeaSpine Holdings Corp | 2022-06-30 | Removed / first absent |
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| Figs Inc | Figs Inc | 2023-06-30 | Removed / first absent |
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| PAVmed Inc | PAVmed Inc | 2021-12-31 | Removed / first absent |
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| Zomedica Corp | Zomedica Corp | 2022-06-30 | Removed / first absent |
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| Butterfly Network Inc | Butterfly Network Inc | 2023-09-30 | Removed / first absent |
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| Asensus Surgical Inc | Asensus Surgical Inc | 2022-03-31 | Removed / first absent |
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| Senseonics Holdings Inc | Senseonics Holdings Inc | 2023-09-30 | Removed / first absent |
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| Aspira Women's Health Inc | Aspira Women's Health Inc | 2021-09-30 | Removed / first absent |
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| Outset Medical Inc | Outset Medical Inc | 2023-12-31 | Removed / first absent |
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| Pulmonx Corp | Pulmonx Corp | 2022-12-31 | Removed / first absent |
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| Eargo Inc | Eargo Inc | 2021-09-30 | Removed / first absent |
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| Intersect ENT Inc | Intersect ENT Inc | 2022-06-30 | Removed / first absent |
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| Cutera Inc | Cutera Inc | 2023-09-30 | Removed / first absent |
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| BioLife Solutions Inc | BioLife Solutions Inc | 2022-12-31 | Removed / first absent |
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| ViewRay Inc | ViewRay Inc | 2023-06-30 | Removed / first absent |
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| Inari Medical Inc | Inari Medical Inc | 2025-03-31 | Removed / first absent |
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| Vapotherm Inc | Vapotherm Inc | 2022-06-30 | Removed / first absent |
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| Shockwave Medical Inc | Shockwave Medical Inc | 2024-06-30 | Removed / first absent |
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| Silk Road Medical Inc | Silk Road Medical Inc | 2024-09-30 | Removed / first absent |
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| GenMark Diagnostics Inc | GenMark Diagnostics Inc | 2021-06-30 | Removed / first absent |
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| Axonics Modulation Technologies Inc | Axonics Modulation Technologies Inc | 2024-12-31 | Removed / first absent |
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| SmileDirectClub Inc | SmileDirectClub Inc | 2022-03-31 | Removed / first absent |
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| State Street Global Advisors | State Street Global Advisors | 2024-09-30 | Removed / first absent |
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| Cooper Cos Inc/The | Cooper Cos Inc/The | 2024-03-31 | Removed / first absent |
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| Varian Medical Systems Inc | Varian Medical Systems Inc | 2021-06-30 | Removed / first absent |
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| Danaher Corp | Danaher Corp | 2021-12-31 | Removed / first absent |
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| ABIOMED Inc | ABIOMED Inc | 2022-12-31 | Removed / first absent |
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| Nevro Corp | Nevro Corp | 2024-09-30 | Removed / first absent |
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| Quidel Corp | Quidel Corp | 2022-06-30 | Removed / first absent |
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| Cardiovascular Systems Inc | Cardiovascular Systems Inc | 2023-06-30 | Removed / first absent |
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| Natus Medical Inc | Natus Medical Inc | 2022-09-30 | Removed / first absent |
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| Cerus Corp | Cerus Corp | 2023-12-31 | Removed / first absent |
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| Surmodics Inc | Surmodics Inc | 2023-06-30 | Removed / first absent |
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| Heska Corp | Heska Corp | 2023-06-30 | Removed / first absent |
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| AxoGen Inc | AxoGen Inc | 2023-09-30 | Removed / first absent |
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| Cutera Inc | Cutera Inc | 2020-06-30 | Removed / first absent |
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| West Pharmaceutical Services Inc | West Pharmaceutical Services Inc | 2021-12-31 | Removed / first absent |
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| Hill-Rom Holdings Inc | Hill-Rom Holdings Inc | 2021-12-31 | Removed / first absent |
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| Atrion Corp | Atrion Corp | 2024-09-30 | Removed / first absent |
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| Meridian Bioscience Inc | Meridian Bioscience Inc | 2023-03-31 | Removed / first absent |
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| Mesa Laboratories Inc | Mesa Laboratories Inc | 2023-06-30 | Removed / first absent |
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| Tactile Systems Technology Inc | Tactile Systems Technology Inc | 2022-06-30 | Removed / first absent |
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| Inogen Inc | Inogen Inc | 2023-06-30 | Removed / first absent |
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| Cantel Medical Corp | Cantel Medical Corp | 2021-06-30 | Removed / first absent |
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| NuVasive Inc | NuVasive Inc | 2023-09-30 | Removed / first absent |
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| AngioDynamics Inc | AngioDynamics Inc | 2023-12-31 | Removed / first absent |
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| OraSure Technologies Inc | OraSure Technologies Inc | 2022-09-30 | Removed / first absent |
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| Antares Pharma Inc | Antares Pharma Inc | 2021-06-30 | Removed / first absent |
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| CryoPort Inc | CryoPort Inc | 2022-09-30 | Removed / first absent |
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