SBIO additions & removals
Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.
Additions
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| Sarepta Therapeutics Inc | Sarepta Therapeutics Inc | 2026-02-28 | Added / first present |
| Aclaris Therapeutics Inc | Aclaris Therapeutics Inc | 2026-02-28 | Added / first present |
| Kalvista Pharmaceuticals Inc | Kalvista Pharmaceuticals Inc | 2026-02-28 | Added / first present |
| Corvus Pharmaceuticals Inc | Corvus Pharmaceuticals Inc | 2026-02-28 | Added / first present |
| Altimmune Inc | Altimmune Inc | 2026-02-28 | Added / first present |
| Protara Therapeutics Inc | Protara Therapeutics Inc | 2026-02-28 | Added / first present |
| Taysha Gene Therapies Inc | Taysha Gene Therapies Inc | 2026-02-28 | Added / first present |
| Kymera Therapeutics Inc | Kymera Therapeutics Inc | 2026-02-28 | Added / first present |
| Design Therapeutics Inc | Design Therapeutics Inc | 2026-02-28 | Added / first present |
| Amylyx Pharmaceuticals Inc | Amylyx Pharmaceuticals Inc | 2026-02-28 | Added / first present |
| Mineralys Therapeutics Inc | Mineralys Therapeutics Inc | 2026-02-28 | Added / first present |
| Zura Bio Ltd | Zura Bio Ltd | 2026-02-28 | Added / first present |
| Spyre Therapeutics Inc | Spyre Therapeutics Inc | 2026-02-28 | Added / first present |
| Neurogene Inc | Neurogene Inc | 2026-02-28 | Added / first present |
| Alto Neuroscience Inc | Alto Neuroscience Inc | 2026-02-28 | Added / first present |
| Arrivent Biopharma Inc | Arrivent Biopharma Inc | 2026-02-28 | Added / first present |
| Tectonic Therapeutic Inc | Tectonic Therapeutic Inc | 2026-02-28 | Added / first present |
| Oruka Therapeutics Inc | Oruka Therapeutics Inc | 2026-02-28 | Added / first present |
| Forte Biosciences Inc | Forte Biosciences Inc | 2026-02-28 | Added / first present |
| Sionna Therapeutics Inc | Sionna Therapeutics Inc | 2026-02-28 | Added / first present |
| Aardvark Therapeutics Inc | Aardvark Therapeutics Inc | 2026-02-28 | Added / first present |
| 2600057D | Novo Nordisk A/s | 2026-02-28 | Added / first present |
| Oculis Holding Ag | Oculis Holding Ag | 2026-02-28 | Added / first present |
| Apellis Pharmaceuticals Inc | Apellis Pharmaceuticals Inc | 2025-08-31 | Added / first present |
| Arrowhead Pharmaceuticals Inc | Arrowhead Pharmaceuticals Inc | 2025-08-31 | Added / first present |
| Regenxbio Inc | Regenxbio Inc | 2025-08-31 | Added / first present |
| Kura Oncology Inc | Kura Oncology Inc | 2025-08-31 | Added / first present |
| Akebia Therapeutics Inc | Akebia Therapeutics Inc | 2025-08-31 | Added / first present |
| Viking Therapeutics Inc | Viking Therapeutics Inc | 2025-08-31 | Added / first present |
| Geron Corp | Geron Corp | 2025-08-31 | Added / first present |
| Cytokinetics Inc | Cytokinetics Inc | 2025-08-31 | Added / first present |
| Krystal Biotech Inc | Krystal Biotech Inc | 2025-08-31 | Added / first present |
| Gossamer Bio Inc | Gossamer Bio Inc | 2025-08-31 | Added / first present |
| Trevi Therapeutics Inc | Trevi Therapeutics Inc | 2025-08-31 | Added / first present |
| Vaxcyte Inc | Vaxcyte Inc | 2025-08-31 | Added / first present |
| Relay Therapeutics Inc | Relay Therapeutics Inc | 2025-08-31 | Added / first present |
| Travere Therapeutics Inc | Travere Therapeutics Inc | 2025-08-31 | Added / first present |
| Atea Pharmaceuticals Inc | Atea Pharmaceuticals Inc | 2025-08-31 | Added / first present |
| Ars Pharmaceuticals Inc | Ars Pharmaceuticals Inc | 2025-08-31 | Added / first present |
| Delcath Systems Inc | Delcath Systems Inc | 2025-08-31 | Added / first present |
| Terns Pharmaceuticals Inc | Terns Pharmaceuticals Inc | 2025-08-31 | Added / first present |
| Nuvalent Inc | Nuvalent Inc | 2025-08-31 | Added / first present |
| Bicycle Therapeutics Plc | Bicycle Therapeutics Plc | 2025-08-31 | Added / first present |
| Candel Therapeutics Inc | Candel Therapeutics Inc | 2025-08-31 | Added / first present |
| Tyra Biosciences Inc | Tyra Biosciences Inc | 2025-08-31 | Added / first present |
| Compass Therapeutics Inc | Compass Therapeutics Inc | 2025-08-31 | Added / first present |
| Arcellx Inc | Arcellx Inc | 2025-08-31 | Added / first present |
| Bicara Therapeutics Inc | Bicara Therapeutics Inc | 2025-08-31 | Added / first present |
| Metsera Inc | Metsera Inc | 2025-08-31 | Added / first present |
| Palvella Therapeutics Inc | Palvella Therapeutics Inc | 2025-08-31 | Added / first present |
| Maze Therapeutics Inc | Maze Therapeutics Inc | 2025-08-31 | Added / first present |
| Tonix Pharmaceuticals Holding Corp | Tonix Pharmaceuticals Holding Corp | 2025-08-31 | Added / first present |
| Immatics Nv | Immatics Nv | 2025-08-31 | Added / first present |
| Rhythm Pharmaceuticals Inc | Rhythm Pharmaceuticals Inc | 2025-02-28 | Added / first present |
| Axsome Therapeutics Inc | Axsome Therapeutics Inc | 2025-02-28 | Added / first present |
| Macrogenics Inc | Macrogenics Inc | 2025-02-28 | Added / first present |
| Novavax Inc | Novavax Inc | 2025-02-28 | Added / first present |
| Aclaris Therapeutics Inc | Aclaris Therapeutics Inc | 2025-02-28 | Added / first present |
| Autolus Therapeutics Plc | Autolus Therapeutics Plc | 2025-02-28 | Added / first present |
| Stoke Therapeutics Inc | Stoke Therapeutics Inc | 2025-02-28 | Added / first present |
| Capricor Therapeutics Inc | Capricor Therapeutics Inc | 2025-02-28 | Added / first present |
| Vir Biotechnology Inc | Vir Biotechnology Inc | 2025-02-28 | Added / first present |
| Larimar Therapeutics Inc | Larimar Therapeutics Inc | 2025-02-28 | Added / first present |
| Immunome Inc | Immunome Inc | 2025-02-28 | Added / first present |
| Nuvation Bio Inc | Nuvation Bio Inc | 2025-02-28 | Added / first present |
| Eledon Pharmaceuticals Inc | Eledon Pharmaceuticals Inc | 2025-02-28 | Added / first present |
| Rezolute Inc | Rezolute Inc | 2025-02-28 | Added / first present |
| Astria Therapeutics Inc | Astria Therapeutics Inc | 2025-02-28 | Added / first present |
| Amylyx Pharmaceuticals Inc | Amylyx Pharmaceuticals Inc | 2025-02-28 | Added / first present |
| Structure Therapeutics Inc | Structure Therapeutics Inc | 2025-02-28 | Added / first present |
| Rigel Pharmaceuticals Inc | Rigel Pharmaceuticals Inc | 2025-02-28 | Added / first present |
| Cartesian Therapeutics Inc | Cartesian Therapeutics Inc | 2025-02-28 | Added / first present |
| Rapport Therapeutics Inc | Rapport Therapeutics Inc | 2025-02-28 | Added / first present |
| Zenas Biopharma Inc | Zenas Biopharma Inc | 2025-02-28 | Added / first present |
| Mbx Biosciences Inc | Mbx Biosciences Inc | 2025-02-28 | Added / first present |
| Upstream Bio Inc | Upstream Bio Inc | 2025-02-28 | Added / first present |
| Ptc Therapeutics Inc | Ptc Therapeutics Inc | 2024-08-31 | Added / first present |
| Amicus Therapeutics Inc | Amicus Therapeutics Inc | 2024-08-31 | Added / first present |
| Aldeyra Therapeutics Inc | Aldeyra Therapeutics Inc | 2024-08-31 | Added / first present |
| Krystal Biotech Inc | Krystal Biotech Inc | 2024-08-31 | Added / first present |
| Y-mabs Therapeutics Inc | Y-mabs Therapeutics Inc | 2024-08-31 | Added / first present |
| Sutro Biopharma Inc | Sutro Biopharma Inc | 2024-08-31 | Added / first present |
| Celcuity Inc | Celcuity Inc | 2024-08-31 | Added / first present |
| Altimmune Inc | Altimmune Inc | 2024-08-31 | Added / first present |
| Fulgent Genetics Inc | Fulgent Genetics Inc | 2024-08-31 | Added / first present |
| Applied Therapeutics Inc | Applied Therapeutics Inc | 2024-08-31 | Added / first present |
| Theravance Biopharma Inc | Theravance Biopharma Inc | 2024-08-31 | Added / first present |
| Immunovant Inc | Immunovant Inc | 2024-08-31 | Added / first present |
| Urogen Pharma Ltd | Urogen Pharma Ltd | 2024-08-31 | Added / first present |
| Ac Immune Sa | Ac Immune Sa | 2024-08-31 | Added / first present |
| Annexon Inc | Annexon Inc | 2024-08-31 | Added / first present |
| Cogent Biosciences Inc | Cogent Biosciences Inc | 2024-08-31 | Added / first present |
| Longboard Pharmaceuticals Inc | Longboard Pharmaceuticals Inc | 2024-08-31 | Added / first present |
| Erasca Inc | Erasca Inc | 2024-08-31 | Added / first present |
| Hillevax Inc | Hillevax Inc | 2024-08-31 | Added / first present |
| Prokidney Corp | Prokidney Corp | 2024-08-31 | Added / first present |
| Apogee Therapeutics Inc | Apogee Therapeutics Inc | 2024-08-31 | Added / first present |
| Tourmaline Bio Inc | Tourmaline Bio Inc | 2024-08-31 | Added / first present |
| Dianthus Therapeutics Inc | Dianthus Therapeutics Inc | 2024-08-31 | Added / first present |
| Cg Oncology Inc | Cg Oncology Inc | 2024-08-31 | Added / first present |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2024-08-31 | Added / first present |
| Cargo Therapeutics Inc | Cargo Therapeutics Inc | 2024-08-31 | Added / first present |
| Kyverna Therapeutics Inc | Kyverna Therapeutics Inc | 2024-08-31 | Added / first present |
| Alto Neuroscience Inc | Alto Neuroscience Inc | 2024-08-31 | Added / first present |
| Arrivent Biopharma Inc | Arrivent Biopharma Inc | 2024-08-31 | Added / first present |
| Inhibrx Biosciences Inc | Inhibrx Biosciences Inc | 2024-08-31 | Added / first present |
| Newamsterdam Pharma Co Nv | Newamsterdam Pharma Co Nv | 2024-08-31 | Added / first present |
| Pharvaris Nv | Pharvaris Nv | 2024-08-31 | Added / first present |
| Gh Research Plc | Gh Research Plc | 2024-08-31 | Added / first present |
| Opko Health Inc | Opko Health Inc | 2024-02-29 | Added / first present |
| Intellia Therapeutics Inc | Intellia Therapeutics Inc | 2024-02-29 | Added / first present |
| Savara Inc | Savara Inc | 2024-02-29 | Added / first present |
| Liquidia Corp | Liquidia Corp | 2024-02-29 | Added / first present |
| Alpine Immune Sciences Inc | Alpine Immune Sciences Inc | 2024-02-29 | Added / first present |
| Fulcrum Therapeutics Inc | Fulcrum Therapeutics Inc | 2024-02-29 | Added / first present |
| Mirum Pharmaceuticals Inc | Mirum Pharmaceuticals Inc | 2024-02-29 | Added / first present |
| Revolution Medicines Inc | Revolution Medicines Inc | 2024-02-29 | Added / first present |
| Merus Nv | Merus Nv | 2024-02-29 | Added / first present |
| Inhibrx Inc | Inhibrx Inc | 2024-02-29 | Added / first present |
| Inozyme Pharma Inc | Inozyme Pharma Inc | 2024-02-29 | Added / first present |
| Olema Pharmaceuticals Inc | Olema Pharmaceuticals Inc | 2024-02-29 | Added / first present |
| 4d Molecular Therapeutics Inc | 4d Molecular Therapeutics Inc | 2024-02-29 | Added / first present |
| Biomea Fusion Inc | Biomea Fusion Inc | 2024-02-29 | Added / first present |
| Reneo Pharmaceuticals Inc | Reneo Pharmaceuticals Inc | 2024-02-29 | Added / first present |
| Compass Pathways Plc | Compass Pathways Plc | 2024-02-29 | Added / first present |
| Soleno Therapeutics Inc | Soleno Therapeutics Inc | 2024-02-29 | Added / first present |
| Moonlake Immunotherapeutics | Moonlake Immunotherapeutics | 2024-02-29 | Added / first present |
| Acelyrin Inc | Acelyrin Inc | 2024-02-29 | Added / first present |
| Neumora Therapeutics Inc | Neumora Therapeutics Inc | 2024-02-29 | Added / first present |
| 2334482D | Astrazeneca Plc | 2024-02-29 | Added / first present |
| Ambrx Biopharma Inc | Ambrx Biopharma Inc | 2023-11-30 | Added / first present |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2023-08-31 | Added / first present |
| Amicus Therapeutics Inc | Amicus Therapeutics Inc | 2023-08-31 | Added / first present |
| Ironwood Pharmaceuticals Inc | Ironwood Pharmaceuticals Inc | 2023-08-31 | Added / first present |
| Insmed Inc | Insmed Inc | 2023-08-31 | Added / first present |
| Deciphera Pharmaceuticals Inc | Deciphera Pharmaceuticals Inc | 2023-08-31 | Added / first present |
| Macrogenics Inc | Macrogenics Inc | 2023-08-31 | Added / first present |
| Karyopharm Therapeutics Inc | Karyopharm Therapeutics Inc | 2023-08-31 | Added / first present |
| Scholar Rock Holding Corp | Scholar Rock Holding Corp | 2023-08-31 | Added / first present |
| Kalvista Pharmaceuticals Inc | Kalvista Pharmaceuticals Inc | 2023-08-31 | Added / first present |
| Autolus Therapeutics Plc | Autolus Therapeutics Plc | 2023-08-31 | Added / first present |
| Morphic Holding Inc | Morphic Holding Inc | 2023-08-31 | Added / first present |
| Arcturus Therapeutics Holdings Inc | Arcturus Therapeutics Holdings Inc | 2023-08-31 | Added / first present |
| Ideaya Biosciences Inc | Ideaya Biosciences Inc | 2023-08-31 | Added / first present |
| Kiniksa Pharmaceuticals Ltd | Kiniksa Pharmaceuticals Ltd | 2023-08-31 | Added / first present |
| Zentalis Pharmaceuticals Inc | Zentalis Pharmaceuticals Inc | 2023-08-31 | Added / first present |
| Mimedx Group Inc | Mimedx Group Inc | 2023-08-31 | Added / first present |
| Ars Pharmaceuticals Inc | Ars Pharmaceuticals Inc | 2023-08-31 | Added / first present |
| Summit Therapeutics Inc | Summit Therapeutics Inc | 2023-08-31 | Added / first present |
| Inflarx Nv | Inflarx Nv | 2023-08-31 | Added / first present |
| Viridian Therapeutics Inc | Viridian Therapeutics Inc | 2023-08-31 | Added / first present |
| Ambrx Biopharma Inc | Ambrx Biopharma Inc | 2023-08-31 | Added / first present |
| Compass Therapeutics Inc | Compass Therapeutics Inc | 2023-08-31 | Added / first present |
| Prokidney Corp | Prokidney Corp | 2023-08-31 | Added / first present |
| Disc Medicine Inc | Disc Medicine Inc | 2023-08-31 | Added / first present |
| Mineralys Therapeutics Inc | Mineralys Therapeutics Inc | 2023-08-31 | Added / first present |
| Verona Pharma Plc | Verona Pharma Plc | 2023-05-31 | Added / first present |
| Ngm Biopharmaceuticals Inc | Ngm Biopharmaceuticals Inc | 2023-05-31 | Added / first present |
| Mersana Therapeutics Inc | Mersana Therapeutics Inc | 2023-05-31 | Added / first present |
| Cassava Sciences Inc | Cassava Sciences Inc | 2023-05-31 | Added / first present |
| Marinus Pharmaceuticals Inc | Marinus Pharmaceuticals Inc | 2023-05-31 | Added / first present |
| Terns Pharmaceuticals Inc | Terns Pharmaceuticals Inc | 2023-05-31 | Added / first present |
| Aerovate Therapeutics Inc | Aerovate Therapeutics Inc | 2023-05-31 | Added / first present |
| Aura Biosciences Inc | Aura Biosciences Inc | 2023-05-31 | Added / first present |
| Belite Bio Inc | Belite Bio Inc | 2023-05-31 | Added / first present |
| Ultragenyx Pharmaceutical Inc | Ultragenyx Pharmaceutical Inc | 2023-02-28 | Added / first present |
| Blueprint Medicines Corp | Blueprint Medicines Corp | 2023-02-28 | Added / first present |
| Rhythm Pharmaceuticals Inc | Rhythm Pharmaceuticals Inc | 2023-02-28 | Added / first present |
| Cara Therapeutics Inc | Cara Therapeutics Inc | 2023-02-28 | Added / first present |
| Axsome Therapeutics Inc | Axsome Therapeutics Inc | 2023-02-28 | Added / first present |
| Viking Therapeutics Inc | Viking Therapeutics Inc | 2023-02-28 | Added / first present |
| Cymabay Therapeutics Inc | Cymabay Therapeutics Inc | 2023-02-28 | Added / first present |
| Geron Corp | Geron Corp | 2023-02-28 | Added / first present |
| Aclaris Therapeutics Inc | Aclaris Therapeutics Inc | 2023-02-28 | Added / first present |
| Corcept Therapeutics Inc | Corcept Therapeutics Inc | 2023-02-28 | Added / first present |
| Arvinas Inc | Arvinas Inc | 2023-02-28 | Added / first present |
| Gritstone Bio Inc | Gritstone Bio Inc | 2023-02-28 | Added / first present |
| Pds Biotechnology Corp | Pds Biotechnology Corp | 2023-02-28 | Added / first present |
| Fulcrum Therapeutics Inc | Fulcrum Therapeutics Inc | 2023-02-28 | Added / first present |
| 89bio Inc | 89bio Inc | 2023-02-28 | Added / first present |
| Pliant Therapeutics Inc | Pliant Therapeutics Inc | 2023-02-28 | Added / first present |
| Bioatla Inc | Bioatla Inc | 2023-02-28 | Added / first present |
| Atea Pharmaceuticals Inc | Atea Pharmaceuticals Inc | 2023-02-28 | Added / first present |
| Tarsus Pharmaceuticals Inc | Tarsus Pharmaceuticals Inc | 2023-02-28 | Added / first present |
| Edgewise Therapeutics Inc | Edgewise Therapeutics Inc | 2023-02-28 | Added / first present |
| Ventyx Biosciences Inc | Ventyx Biosciences Inc | 2023-02-28 | Added / first present |
| Roivant Sciences Ltd | Roivant Sciences Ltd | 2023-02-28 | Added / first present |
| Arcellx Inc | Arcellx Inc | 2023-02-28 | Added / first present |
| Atai Life Sciences Nv | Atai Life Sciences Nv | 2023-02-28 | Added / first present |
| Amylyx Pharmaceuticals Inc | Amylyx Pharmaceuticals Inc | 2023-02-28 | Added / first present |
| N/A | N/A | 2022-11-30 | Added / first present |
| Omniab Inc/old | Omniab Inc/old | 2022-11-30 | Added / first present |
| Omniab Inc/old | Omniab Inc/old | 2022-11-30 | Added / first present |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2022-08-31 | Added / first present |
| Mirati Therapeutics Inc | Mirati Therapeutics Inc | 2022-08-31 | Added / first present |
| Global Blood Therapeutics Inc | Global Blood Therapeutics Inc | 2022-08-31 | Added / first present |
| Arrowhead Pharmaceuticals Inc | Arrowhead Pharmaceuticals Inc | 2022-08-31 | Added / first present |
| Ironwood Pharmaceuticals Inc | Ironwood Pharmaceuticals Inc | 2022-08-31 | Added / first present |
| Denali Therapeutics Inc | Denali Therapeutics Inc | 2022-08-31 | Added / first present |
| Editas Medicine Inc | Editas Medicine Inc | 2022-08-31 | Added / first present |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2022-08-31 | Added / first present |
| Intellia Therapeutics Inc | Intellia Therapeutics Inc | 2022-08-31 | Added / first present |
| Kura Oncology Inc | Kura Oncology Inc | 2022-08-31 | Added / first present |
| Vericel Corp | Vericel Corp | 2022-08-31 | Added / first present |
| Biocryst Pharmaceuticals Inc | Biocryst Pharmaceuticals Inc | 2022-08-31 | Added / first present |
| Novavax Inc | Novavax Inc | 2022-08-31 | Added / first present |
| Eagle Pharmaceuticals Inc/de | Eagle Pharmaceuticals Inc/de | 2022-08-31 | Added / first present |
| Zai Lab Ltd | Zai Lab Ltd | 2022-08-31 | Added / first present |
| Crispr Therapeutics Ag | Crispr Therapeutics Ag | 2022-08-31 | Added / first present |
| Ascendis Pharma A/s | Ascendis Pharma A/s | 2022-08-31 | Added / first present |
| Amarin Corp Plc | Amarin Corp Plc | 2022-08-31 | Added / first present |
| Adaptimmune Therapeutics Plc | Adaptimmune Therapeutics Plc | 2022-08-31 | Added / first present |
| Aurinia Pharmaceuticals Inc | Aurinia Pharmaceuticals Inc | 2022-08-31 | Added / first present |
| Concert Pharmaceuticals Inc | Concert Pharmaceuticals Inc | 2022-08-31 | Added / first present |
| Celldex Therapeutics Inc | Celldex Therapeutics Inc | 2022-08-31 | Added / first present |
| Vbi Vaccines Inc | Vbi Vaccines Inc | 2022-08-31 | Added / first present |
| Ocugen Inc | Ocugen Inc | 2022-08-31 | Added / first present |
| Ideaya Biosciences Inc | Ideaya Biosciences Inc | 2022-08-31 | Added / first present |
| Vir Biotechnology Inc | Vir Biotechnology Inc | 2022-08-31 | Added / first present |
| Avidity Biosciences Inc | Avidity Biosciences Inc | 2022-08-31 | Added / first present |
| Repare Therapeutics Inc | Repare Therapeutics Inc | 2022-08-31 | Added / first present |
| I-mab | I-mab | 2022-08-31 | Added / first present |
| Vaxcyte Inc | Vaxcyte Inc | 2022-08-31 | Added / first present |
| Pmv Pharmaceuticals Inc | Pmv Pharmaceuticals Inc | 2022-08-31 | Added / first present |
| Adicet Bio Inc | Adicet Bio Inc | 2022-08-31 | Added / first present |
| Iteos Therapeutics Inc | Iteos Therapeutics Inc | 2022-08-31 | Added / first present |
| C4 Therapeutics Inc | C4 Therapeutics Inc | 2022-08-31 | Added / first present |
| 4d Molecular Therapeutics Inc | 4d Molecular Therapeutics Inc | 2022-08-31 | Added / first present |
| Cullinan Oncology Inc | Cullinan Oncology Inc | 2022-08-31 | Added / first present |
| Viridian Therapeutics Inc | Viridian Therapeutics Inc | 2022-08-31 | Added / first present |
| Essa Pharma Inc | Essa Pharma Inc | 2022-08-31 | Added / first present |
| Vera Therapeutics Inc | Vera Therapeutics Inc | 2022-08-31 | Added / first present |
| Point Biopharma Global Inc | Point Biopharma Global Inc | 2022-08-31 | Added / first present |
| Tango Therapeutics Inc | Tango Therapeutics Inc | 2022-08-31 | Added / first present |
| Icosavax Inc | Icosavax Inc | 2022-08-31 | Added / first present |
| Adagio Therapeutics Inc | Adagio Therapeutics Inc | 2022-08-31 | Added / first present |
| Erasca Inc | Erasca Inc | 2022-08-31 | Added / first present |
| Nuvalent Inc | Nuvalent Inc | 2022-08-31 | Added / first present |
| Bicycle Therapeutics Plc | Bicycle Therapeutics Plc | 2022-08-31 | Added / first present |
| Rallybio Corp | Rallybio Corp | 2022-08-31 | Added / first present |
| Centessa Pharmaceuticals Plc | Centessa Pharmaceuticals Plc | 2022-08-31 | Added / first present |
| Eqrx Inc | Eqrx Inc | 2022-08-31 | Added / first present |
| Hillevax Inc | Hillevax Inc | 2022-08-31 | Added / first present |
| Moonlake Immunotherapeutics | Moonlake Immunotherapeutics | 2022-08-31 | Added / first present |
| Tonix Pharmaceuticals Holding Corp | Tonix Pharmaceuticals Holding Corp | 2022-05-31 | Added / first present |
| Ionis Pharmaceuticals Inc | Ionis Pharmaceuticals Inc | 2022-02-28 | Added / first present |
| Allakos Inc | Allakos Inc | 2022-02-28 | Added / first present |
| Galapagos Nv | Galapagos Nv | 2022-02-28 | Added / first present |
| Checkpoint Therapeutics Inc | Checkpoint Therapeutics Inc | 2022-02-28 | Added / first present |
| Insmed Inc | Insmed Inc | 2022-02-28 | Added / first present |
| Opko Health Inc | Opko Health Inc | 2022-02-28 | Added / first present |
| Rigel Pharmaceuticals Inc | Rigel Pharmaceuticals Inc | 2022-02-28 | Added / first present |
| Mannkind Corp | Mannkind Corp | 2022-02-28 | Added / first present |
| Agenus Inc | Agenus Inc | 2022-02-28 | Added / first present |
| Surface Oncology Inc | Surface Oncology Inc | 2022-02-28 | Added / first present |
| Kalvista Pharmaceuticals Inc | Kalvista Pharmaceuticals Inc | 2022-02-28 | Added / first present |
| Autolus Therapeutics Plc | Autolus Therapeutics Plc | 2022-02-28 | Added / first present |
| Aeglea Biotherapeutics Inc | Aeglea Biotherapeutics Inc | 2022-02-28 | Added / first present |
| Arbutus Biopharma Corp | Arbutus Biopharma Corp | 2022-02-28 | Added / first present |
| Jounce Therapeutics Inc | Jounce Therapeutics Inc | 2022-02-28 | Added / first present |
| Protagonist Therapeutics Inc | Protagonist Therapeutics Inc | 2022-02-28 | Added / first present |
| Gritstone Bio Inc | Gritstone Bio Inc | 2022-02-28 | Added / first present |
| Anavex Life Sciences Corp | Anavex Life Sciences Corp | 2022-02-28 | Added / first present |
| Pds Biotechnology Corp | Pds Biotechnology Corp | 2022-02-28 | Added / first present |
| Vaxart Inc | Vaxart Inc | 2022-02-28 | Added / first present |
| Atossa Therapeutics Inc | Atossa Therapeutics Inc | 2022-02-28 | Added / first present |
| Uniqure Nv | Uniqure Nv | 2022-02-28 | Added / first present |
| Proqr Therapeutics Nv | Proqr Therapeutics Nv | 2022-02-28 | Added / first present |
| Oyster Point Pharma Inc | Oyster Point Pharma Inc | 2022-02-28 | Added / first present |
| Tonix Pharmaceuticals Holding Corp | Tonix Pharmaceuticals Holding Corp | 2022-02-28 | Added / first present |
| Myovant Sciences Ltd | Myovant Sciences Ltd | 2022-02-28 | Added / first present |
| Beyondspring Inc | Beyondspring Inc | 2022-02-28 | Added / first present |
| Merus Nv | Merus Nv | 2022-02-28 | Added / first present |
| Kronos Bio Inc | Kronos Bio Inc | 2022-02-28 | Added / first present |
| Bellus Health Inc | Bellus Health Inc | 2022-02-28 | Added / first present |
| Mimedx Group Inc | Mimedx Group Inc | 2022-02-28 | Added / first present |
| Cogent Biosciences Inc | Cogent Biosciences Inc | 2022-02-28 | Added / first present |
| Prometheus Biosciences Inc | Prometheus Biosciences Inc | 2022-02-28 | Added / first present |
| Recursion Pharmaceuticals Inc | Recursion Pharmaceuticals Inc | 2022-02-28 | Added / first present |
| Instil Bio Inc | Instil Bio Inc | 2022-02-28 | Added / first present |
| Day One Biopharmaceuticals Inc | Day One Biopharmaceuticals Inc | 2022-02-28 | Added / first present |
| Impel Neuropharma Inc | Impel Neuropharma Inc | 2022-02-28 | Added / first present |
| Longeveron Inc | Longeveron Inc | 2022-02-28 | Added / first present |
| Imago Biosciences Inc | Imago Biosciences Inc | 2022-02-28 | Added / first present |
| Compass Pathways Plc | Compass Pathways Plc | 2022-02-28 | Added / first present |
| Aadi Bioscience Inc | Aadi Bioscience Inc | 2022-02-28 | Added / first present |
| Lianbio | Lianbio | 2022-02-28 | Added / first present |
| Innate Pharma Sa | Innate Pharma Sa | 2022-02-28 | Added / first present |
| Effector Therapeutics Inc | Effector Therapeutics Inc | 2022-02-28 | Added / first present |
| Sab Biotherapeutics Inc | Sab Biotherapeutics Inc | 2022-02-28 | Added / first present |
| Valneva Se | Valneva Se | 2022-02-28 | Added / first present |
| Sage Therapeutics Inc | Sage Therapeutics Inc | 2021-08-31 | Added / first present |
| Acadia Pharmaceuticals Inc | Acadia Pharmaceuticals Inc | 2021-08-31 | Added / first present |
| Syndax Pharmaceuticals Inc | Syndax Pharmaceuticals Inc | 2021-08-31 | Added / first present |
| Iovance Biotherapeutics Inc | Iovance Biotherapeutics Inc | 2021-08-31 | Added / first present |
| Amicus Therapeutics Inc | Amicus Therapeutics Inc | 2021-08-31 | Added / first present |
| G1 Therapeutics Inc | G1 Therapeutics Inc | 2021-08-31 | Added / first present |
| Atara Biotherapeutics Inc | Atara Biotherapeutics Inc | 2021-08-31 | Added / first present |
| Macrogenics Inc | Macrogenics Inc | 2021-08-31 | Added / first present |
| Immunogen Inc | Immunogen Inc | 2021-08-31 | Added / first present |
| Tg Therapeutics Inc | Tg Therapeutics Inc | 2021-08-31 | Added / first present |
| Y-mabs Therapeutics Inc | Y-mabs Therapeutics Inc | 2021-08-31 | Added / first present |
| Orchard Therapeutics Plc | Orchard Therapeutics Plc | 2021-08-31 | Added / first present |
| Adverum Biotechnologies Inc | Adverum Biotechnologies Inc | 2021-08-31 | Added / first present |
| Eiger Biopharmaceuticals Inc | Eiger Biopharmaceuticals Inc | 2021-08-31 | Added / first present |
| Savara Inc | Savara Inc | 2021-08-31 | Added / first present |
| Stoke Therapeutics Inc | Stoke Therapeutics Inc | 2021-08-31 | Added / first present |
| Arcturus Therapeutics Holdings Inc | Arcturus Therapeutics Holdings Inc | 2021-08-31 | Added / first present |
| Marker Therapeutics Inc | Marker Therapeutics Inc | 2021-08-31 | Added / first present |
| Kadmon Holdings Inc | Kadmon Holdings Inc | 2021-08-31 | Added / first present |
| Organogenesis Holdings Inc | Organogenesis Holdings Inc | 2021-08-31 | Added / first present |
| Infinity Pharmaceuticals Inc | Infinity Pharmaceuticals Inc | 2021-08-31 | Added / first present |
| Kodiak Sciences Inc | Kodiak Sciences Inc | 2021-08-31 | Added / first present |
| Alpine Immune Sciences Inc | Alpine Immune Sciences Inc | 2021-08-31 | Added / first present |
| Inmune Bio Inc | Inmune Bio Inc | 2021-08-31 | Added / first present |
| Vistagen Therapeutics Inc | Vistagen Therapeutics Inc | 2021-08-31 | Added / first present |
| Rapt Therapeutics Inc | Rapt Therapeutics Inc | 2021-08-31 | Added / first present |
| Meiragtx Holdings Plc | Meiragtx Holdings Plc | 2021-08-31 | Added / first present |
| Aveo Pharmaceuticals Inc | Aveo Pharmaceuticals Inc | 2021-08-31 | Added / first present |
| Keros Therapeutics Inc | Keros Therapeutics Inc | 2021-08-31 | Added / first present |
| Applied Molecular Transport Inc | Applied Molecular Transport Inc | 2021-08-31 | Added / first present |
| Forte Biosciences Inc | Forte Biosciences Inc | 2021-08-31 | Added / first present |
| Cardiff Oncology Inc | Cardiff Oncology Inc | 2021-08-31 | Added / first present |
| Annexon Inc | Annexon Inc | 2021-08-31 | Added / first present |
| Alx Oncology Holdings Inc | Alx Oncology Holdings Inc | 2021-08-31 | Added / first present |
| Cerevel Therapeutics Holdings Inc | Cerevel Therapeutics Holdings Inc | 2021-08-31 | Added / first present |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2021-08-31 | Added / first present |
| Bioatla Inc | Bioatla Inc | 2021-08-31 | Added / first present |
| Spruce Biosciences Inc | Spruce Biosciences Inc | 2021-08-31 | Added / first present |
| Immunocore Holdings Plc | Immunocore Holdings Plc | 2021-08-31 | Added / first present |
| Gemini Therapeutics Inc | Gemini Therapeutics Inc | 2021-08-31 | Added / first present |
| Sensei Biotherapeutics Inc | Sensei Biotherapeutics Inc | 2021-08-31 | Added / first present |
| Clene Inc | Clene Inc | 2021-08-31 | Added / first present |
| Immutep Ltd | Immutep Ltd | 2021-08-31 | Added / first present |
| Adc Therapeutics Sa | Adc Therapeutics Sa | 2021-08-31 | Added / first present |
| Taiwan Liposome Co Ltd | Taiwan Liposome Co Ltd | 2021-08-31 | Added / first present |
| Bluebird Bio Inc | Bluebird Bio Inc | 2021-02-28 | Added / first present |
| Agios Pharmaceuticals Inc | Agios Pharmaceuticals Inc | 2021-02-28 | Added / first present |
| Xencor Inc | Xencor Inc | 2021-02-28 | Added / first present |
| Insmed Inc | Insmed Inc | 2021-02-28 | Added / first present |
| Regenxbio Inc | Regenxbio Inc | 2021-02-28 | Added / first present |
| Radius Health Inc | Radius Health Inc | 2021-02-28 | Added / first present |
| Esperion Therapeutics Inc | Esperion Therapeutics Inc | 2021-02-28 | Added / first present |
| Sangamo Therapeutics Inc | Sangamo Therapeutics Inc | 2021-02-28 | Added / first present |
| Ziopharm Oncology Inc | Ziopharm Oncology Inc | 2021-02-28 | Added / first present |
| Cytomx Therapeutics Inc | Cytomx Therapeutics Inc | 2021-02-28 | Added / first present |
| Geron Corp | Geron Corp | 2021-02-28 | Added / first present |
| Inovio Pharmaceuticals Inc | Inovio Pharmaceuticals Inc | 2021-02-28 | Added / first present |
| Aldeyra Therapeutics Inc | Aldeyra Therapeutics Inc | 2021-02-28 | Added / first present |
| Verastem Inc | Verastem Inc | 2021-02-28 | Added / first present |
| Eagle Pharmaceuticals Inc/de | Eagle Pharmaceuticals Inc/de | 2021-02-28 | Added / first present |
| Vanda Pharmaceuticals Inc | Vanda Pharmaceuticals Inc | 2021-02-28 | Added / first present |
| Cytokinetics Inc | Cytokinetics Inc | 2021-02-28 | Added / first present |
| Arcus Biosciences Inc | Arcus Biosciences Inc | 2021-02-28 | Added / first present |
| Nucana Plc | Nucana Plc | 2021-02-28 | Added / first present |
| Seres Therapeutics Inc | Seres Therapeutics Inc | 2021-02-28 | Added / first present |
| Aptinyx Inc | Aptinyx Inc | 2021-02-28 | Added / first present |
| Celldex Therapeutics Inc | Celldex Therapeutics Inc | 2021-02-28 | Added / first present |
| Selecta Biosciences Inc | Selecta Biosciences Inc | 2021-02-28 | Added / first present |
| Chimerix Inc | Chimerix Inc | 2021-02-28 | Added / first present |
| Fortress Biotech Inc | Fortress Biotech Inc | 2021-02-28 | Added / first present |
| Kezar Life Sciences Inc | Kezar Life Sciences Inc | 2021-02-28 | Added / first present |
| Immunic Inc | Immunic Inc | 2021-02-28 | Added / first present |
| Vaxart Inc | Vaxart Inc | 2021-02-28 | Added / first present |
| Altimmune Inc | Altimmune Inc | 2021-02-28 | Added / first present |
| Mirum Pharmaceuticals Inc | Mirum Pharmaceuticals Inc | 2021-02-28 | Added / first present |
| Prothena Corp Plc | Prothena Corp Plc | 2021-02-28 | Added / first present |
| Kiniksa Pharmaceuticals Ltd | Kiniksa Pharmaceuticals Ltd | 2021-02-28 | Added / first present |
| Immunovant Inc | Immunovant Inc | 2021-02-28 | Added / first present |
| 89bio Inc | 89bio Inc | 2021-02-28 | Added / first present |
| Ac Immune Sa | Ac Immune Sa | 2021-02-28 | Added / first present |
| Forma Therapeutics Holdings Inc | Forma Therapeutics Holdings Inc | 2021-02-28 | Added / first present |
| Protara Therapeutics Inc | Protara Therapeutics Inc | 2021-02-28 | Added / first present |
| Allovir Inc | Allovir Inc | 2021-02-28 | Added / first present |
| Travere Therapeutics Inc | Travere Therapeutics Inc | 2021-02-28 | Added / first present |
| Legend Biotech Corp | Legend Biotech Corp | 2021-02-28 | Added / first present |
| Gamida Cell Ltd | Gamida Cell Ltd | 2021-02-28 | Added / first present |
| Kamada Ltd | Kamada Ltd | 2021-02-28 | Added / first present |
| Affimed Nv | Affimed Nv | 2020-11-30 | Added / first present |
| Chinook Therapeutics Inc | Chinook Therapeutics Inc | 2020-11-30 | Added / first present |
| Inflarx Nv | Inflarx Nv | 2020-11-30 | Added / first present |
| 1835589D | Chinook Therapeutics Inc | 2020-11-30 | Added / first present |
| Blueprint Medicines Corp | Blueprint Medicines Corp | 2020-08-31 | Added / first present |
| Arrowhead Pharmaceuticals Inc | Arrowhead Pharmaceuticals Inc | 2020-08-31 | Added / first present |
| Anaptysbio Inc | Anaptysbio Inc | 2020-08-31 | Added / first present |
| Heron Therapeutics Inc | Heron Therapeutics Inc | 2020-08-31 | Added / first present |
| Karyopharm Therapeutics Inc | Karyopharm Therapeutics Inc | 2020-08-31 | Added / first present |
| Avrobio Inc | Avrobio Inc | 2020-08-31 | Added / first present |
| Emergent Biosolutions Inc | Emergent Biosolutions Inc | 2020-08-31 | Added / first present |
| Y-mabs Therapeutics Inc | Y-mabs Therapeutics Inc | 2020-08-31 | Added / first present |
| Scholar Rock Holding Corp | Scholar Rock Holding Corp | 2020-08-31 | Added / first present |
| Aduro Biotech Inc | Aduro Biotech Inc | 2020-08-31 | Added / first present |
| Xenon Pharmaceuticals Inc | Xenon Pharmaceuticals Inc | 2020-08-31 | Added / first present |
| Molecular Templates Inc | Molecular Templates Inc | 2020-08-31 | Added / first present |
| Ardelyx Inc | Ardelyx Inc | 2020-08-31 | Added / first present |
| Magenta Therapeutics Inc | Magenta Therapeutics Inc | 2020-08-31 | Added / first present |
| Adaptimmune Therapeutics Plc | Adaptimmune Therapeutics Plc | 2020-08-31 | Added / first present |
| Aurinia Pharmaceuticals Inc | Aurinia Pharmaceuticals Inc | 2020-08-31 | Added / first present |
| Syros Pharmaceuticals Inc | Syros Pharmaceuticals Inc | 2020-08-31 | Added / first present |
| American Realty Capital Trust | American Realty Capital Trust | 2020-08-31 | Added / first present |
| CEL Sci Corp | CEL Sci Corp | 2020-08-31 | Added / first present |
| Mei Pharma Inc | Mei Pharma Inc | 2020-08-31 | Added / first present |
| Kodiak Sciences Inc | Kodiak Sciences Inc | 2020-08-31 | Added / first present |
| Iveric Bio Inc | Iveric Bio Inc | 2020-08-31 | Added / first present |
| Aravive Inc | Aravive Inc | 2020-08-31 | Added / first present |
| Bioxcel Therapeutics INC | Bioxcel Therapeutics INC | 2020-08-31 | Added / first present |
| Proqr Therapeutics Nv | Proqr Therapeutics Nv | 2020-08-31 | Added / first present |
| VIR Biotechnology Inc | VIR Biotechnology Inc | 2020-08-31 | Added / first present |
| Viela Bio Inc | Viela Bio Inc | 2020-08-31 | Added / first present |
| Arcutis Biotherapeutics Incorporation | Arcutis Biotherapeutics Incorporation | 2020-08-31 | Added / first present |
| Affimed Nv | Affimed Nv | 2020-08-31 | Added / first present |
| Inflarx Nv | Inflarx Nv | 2020-08-31 | Added / first present |
| Bluebird Bio Inc | Bluebird Bio Inc | 2020-02-29 | Added / first present |
| Portola Pharmaceuticals Inc | Portola Pharmaceuticals Inc | 2020-02-29 | Added / first present |
| Intercept Pharmaceuticals Inc | Intercept Pharmaceuticals Inc | 2020-02-29 | Added / first present |
| Ironwood Pharmaceuticals Inc | Ironwood Pharmaceuticals Inc | 2020-02-29 | Added / first present |
| Coherus Biosciences Inc | Coherus Biosciences Inc | 2020-02-29 | Added / first present |
| Catalyst Pharmaceuticals Inc | Catalyst Pharmaceuticals Inc | 2020-02-29 | Added / first present |
| Rocket Pharmaceuticals Inc | Rocket Pharmaceuticals Inc | 2020-02-29 | Added / first present |
| Cytomx Therapeutics Inc | Cytomx Therapeutics Inc | 2020-02-29 | Added / first present |
| Kalvista Pharmaceuticals Inc | Kalvista Pharmaceuticals Inc | 2020-02-29 | Added / first present |
| Zymeworks Inc | Zymeworks Inc | 2020-02-29 | Added / first present |
| Replimune Group Inc | Replimune Group Inc | 2020-02-29 | Added / first present |
| Alector Inc | Alector Inc | 2020-02-29 | Added / first present |
| Akero Therapeutics Inc | Akero Therapeutics Inc | 2020-02-29 | Added / first present |
| Karuna Therapeutics Inc | Karuna Therapeutics Inc | 2020-02-29 | Added / first present |
| Xoma Corp | Xoma Corp | 2020-02-29 | Added / first present |
| Xbiotech Inc | Xbiotech Inc | 2020-02-29 | Added / first present |
| Cortexyme Inc | Cortexyme Inc | 2020-02-29 | Added / first present |
| Springworks Therapeutics Inc | Springworks Therapeutics Inc | 2020-02-29 | Added / first present |
| Frequency Therapeutics Inc | Frequency Therapeutics Inc | 2020-02-29 | Added / first present |
| Aprea Therapeutics Inc | Aprea Therapeutics Inc | 2020-02-29 | Added / first present |
| Oyster Point Pharma Inc | Oyster Point Pharma Inc | 2020-02-29 | Added / first present |
| Merus Nv | Merus Nv | 2020-02-29 | Added / first present |
Removals
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| Arrowhead Pharmaceuticals Inc | Arrowhead Pharmaceuticals Inc | 2026-02-28 | Removed / first absent |
| Cytokinetics Inc | Cytokinetics Inc | 2026-02-28 | Removed / first absent |
| Krystal Biotech Inc | Krystal Biotech Inc | 2026-02-28 | Removed / first absent |
| Gossamer Bio Inc | Gossamer Bio Inc | 2026-02-28 | Removed / first absent |
| Trevi Therapeutics Inc | Trevi Therapeutics Inc | 2026-02-28 | Removed / first absent |
| Vaxcyte Inc | Vaxcyte Inc | 2026-02-28 | Removed / first absent |
| Terns Pharmaceuticals Inc | Terns Pharmaceuticals Inc | 2026-02-28 | Removed / first absent |
| Nuvalent Inc | Nuvalent Inc | 2026-02-28 | Removed / first absent |
| Arcellx Inc | Arcellx Inc | 2026-02-28 | Removed / first absent |
| Metsera Inc | Metsera Inc | 2025-11-30 | Removed / first absent |
| Tonix Pharmaceuticals Holding Corp | Tonix Pharmaceuticals Holding Corp | 2026-02-28 | Removed / first absent |
| Rhythm Pharmaceuticals Inc | Rhythm Pharmaceuticals Inc | 2026-02-28 | Removed / first absent |
| Axsome Therapeutics Inc | Axsome Therapeutics Inc | 2026-02-28 | Removed / first absent |
| Macrogenics Inc | Macrogenics Inc | 2025-08-31 | Removed / first absent |
| Aclaris Therapeutics Inc | Aclaris Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Autolus Therapeutics Plc | Autolus Therapeutics Plc | 2026-02-28 | Removed / first absent |
| Capricor Therapeutics Inc | Capricor Therapeutics Inc | 2026-02-28 | Removed / first absent |
| Vir Biotechnology Inc | Vir Biotechnology Inc | 2026-02-28 | Removed / first absent |
| Larimar Therapeutics Inc | Larimar Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Immunome Inc | Immunome Inc | 2026-02-28 | Removed / first absent |
| Eledon Pharmaceuticals Inc | Eledon Pharmaceuticals Inc | 2025-08-31 | Removed / first absent |
| Astria Therapeutics Inc | Astria Therapeutics Inc | 2026-02-28 | Removed / first absent |
| Amylyx Pharmaceuticals Inc | Amylyx Pharmaceuticals Inc | 2025-08-31 | Removed / first absent |
| Cartesian Therapeutics Inc | Cartesian Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Ptc Therapeutics Inc | Ptc Therapeutics Inc | 2026-02-28 | Removed / first absent |
| Aldeyra Therapeutics Inc | Aldeyra Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Krystal Biotech Inc | Krystal Biotech Inc | 2025-02-28 | Removed / first absent |
| Y-mabs Therapeutics Inc | Y-mabs Therapeutics Inc | 2025-11-30 | Removed / first absent |
| Sutro Biopharma Inc | Sutro Biopharma Inc | 2025-08-31 | Removed / first absent |
| Altimmune Inc | Altimmune Inc | 2025-02-28 | Removed / first absent |
| Applied Therapeutics Inc | Applied Therapeutics Inc | 2025-02-28 | Removed / first absent |
| Immunovant Inc | Immunovant Inc | 2025-02-28 | Removed / first absent |
| Urogen Pharma Ltd | Urogen Pharma Ltd | 2026-02-28 | Removed / first absent |
| Ac Immune Sa | Ac Immune Sa | 2025-02-28 | Removed / first absent |
| Annexon Inc | Annexon Inc | 2026-02-28 | Removed / first absent |
| Cogent Biosciences Inc | Cogent Biosciences Inc | 2025-02-28 | Removed / first absent |
| Longboard Pharmaceuticals Inc | Longboard Pharmaceuticals Inc | 2025-02-28 | Removed / first absent |
| Erasca Inc | Erasca Inc | 2026-02-28 | Removed / first absent |
| Hillevax Inc | Hillevax Inc | 2025-02-28 | Removed / first absent |
| Prokidney Corp | Prokidney Corp | 2025-08-31 | Removed / first absent |
| Tourmaline Bio Inc | Tourmaline Bio Inc | 2025-11-30 | Removed / first absent |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2026-02-28 | Removed / first absent |
| Cargo Therapeutics Inc | Cargo Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Kyverna Therapeutics Inc | Kyverna Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Alto Neuroscience Inc | Alto Neuroscience Inc | 2025-02-28 | Removed / first absent |
| Arrivent Biopharma Inc | Arrivent Biopharma Inc | 2025-08-31 | Removed / first absent |
| Inhibrx Biosciences Inc | Inhibrx Biosciences Inc | 2025-02-28 | Removed / first absent |
| Gh Research Plc | Gh Research Plc | 2025-02-28 | Removed / first absent |
| Opko Health Inc | Opko Health Inc | 2024-08-31 | Removed / first absent |
| Intellia Therapeutics Inc | Intellia Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Savara Inc | Savara Inc | 2025-08-31 | Removed / first absent |
| Liquidia Corp | Liquidia Corp | 2025-08-31 | Removed / first absent |
| Alpine Immune Sciences Inc | Alpine Immune Sciences Inc | 2024-05-31 | Removed / first absent |
| Fulcrum Therapeutics Inc | Fulcrum Therapeutics Inc | 2025-02-28 | Removed / first absent |
| Revolution Medicines Inc | Revolution Medicines Inc | 2024-08-31 | Removed / first absent |
| Merus Nv | Merus Nv | 2026-02-28 | Removed / first absent |
| Inhibrx Inc | Inhibrx Inc | 2024-05-31 | Removed / first absent |
| Inozyme Pharma Inc | Inozyme Pharma Inc | 2025-02-28 | Removed / first absent |
| 4d Molecular Therapeutics Inc | 4d Molecular Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Biomea Fusion Inc | Biomea Fusion Inc | 2024-08-31 | Removed / first absent |
| Reneo Pharmaceuticals Inc | Reneo Pharmaceuticals Inc | 2024-08-31 | Removed / first absent |
| Compass Pathways Plc | Compass Pathways Plc | 2026-02-28 | Removed / first absent |
| Soleno Therapeutics Inc | Soleno Therapeutics Inc | 2025-02-28 | Removed / first absent |
| Acelyrin Inc | Acelyrin Inc | 2025-05-31 | Removed / first absent |
| Neumora Therapeutics Inc | Neumora Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Ambrx Biopharma Inc | Ambrx Biopharma Inc | 2024-02-29 | Removed / first absent |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2025-02-28 | Removed / first absent |
| Amicus Therapeutics Inc | Amicus Therapeutics Inc | 2024-02-29 | Removed / first absent |
| Ironwood Pharmaceuticals Inc | Ironwood Pharmaceuticals Inc | 2025-08-31 | Removed / first absent |
| Insmed Inc | Insmed Inc | 2024-02-29 | Removed / first absent |
| Deciphera Pharmaceuticals Inc | Deciphera Pharmaceuticals Inc | 2024-08-31 | Removed / first absent |
| Macrogenics Inc | Macrogenics Inc | 2024-08-31 | Removed / first absent |
| Karyopharm Therapeutics Inc | Karyopharm Therapeutics Inc | 2024-02-29 | Removed / first absent |
| Scholar Rock Holding Corp | Scholar Rock Holding Corp | 2024-02-29 | Removed / first absent |
| Kalvista Pharmaceuticals Inc | Kalvista Pharmaceuticals Inc | 2024-02-29 | Removed / first absent |
| Autolus Therapeutics Plc | Autolus Therapeutics Plc | 2024-02-29 | Removed / first absent |
| Morphic Holding Inc | Morphic Holding Inc | 2024-08-31 | Removed / first absent |
| Kiniksa Pharmaceuticals Ltd | Kiniksa Pharmaceuticals Ltd | 2024-08-31 | Removed / first absent |
| Zentalis Pharmaceuticals Inc | Zentalis Pharmaceuticals Inc | 2025-08-31 | Removed / first absent |
| Mimedx Group Inc | Mimedx Group Inc | 2024-08-31 | Removed / first absent |
| Ars Pharmaceuticals Inc | Ars Pharmaceuticals Inc | 2025-02-28 | Removed / first absent |
| Summit Therapeutics Inc | Summit Therapeutics Inc | 2024-08-31 | Removed / first absent |
| Inflarx Nv | Inflarx Nv | 2024-02-29 | Removed / first absent |
| Viridian Therapeutics Inc | Viridian Therapeutics Inc | 2026-02-28 | Removed / first absent |
| Ambrx Biopharma Inc | Ambrx Biopharma Inc | 2023-11-30 | Removed / first absent |
| Compass Therapeutics Inc | Compass Therapeutics Inc | 2024-02-29 | Removed / first absent |
| Prokidney Corp | Prokidney Corp | 2024-02-29 | Removed / first absent |
| Mineralys Therapeutics Inc | Mineralys Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Verona Pharma Plc | Verona Pharma Plc | 2025-08-31 | Removed / first absent |
| Ngm Biopharmaceuticals Inc | Ngm Biopharmaceuticals Inc | 2023-08-31 | Removed / first absent |
| Mersana Therapeutics Inc | Mersana Therapeutics Inc | 2024-02-29 | Removed / first absent |
| Cassava Sciences Inc | Cassava Sciences Inc | 2024-02-29 | Removed / first absent |
| Marinus Pharmaceuticals Inc | Marinus Pharmaceuticals Inc | 2023-08-31 | Removed / first absent |
| Terns Pharmaceuticals Inc | Terns Pharmaceuticals Inc | 2024-02-29 | Removed / first absent |
| Aerovate Therapeutics Inc | Aerovate Therapeutics Inc | 2024-08-31 | Removed / first absent |
| Aura Biosciences Inc | Aura Biosciences Inc | 2025-08-31 | Removed / first absent |
| Belite Bio Inc | Belite Bio Inc | 2023-08-31 | Removed / first absent |
| Ultragenyx Pharmaceutical Inc | Ultragenyx Pharmaceutical Inc | 2023-08-31 | Removed / first absent |
| Blueprint Medicines Corp | Blueprint Medicines Corp | 2023-08-31 | Removed / first absent |
| Rhythm Pharmaceuticals Inc | Rhythm Pharmaceuticals Inc | 2024-08-31 | Removed / first absent |
| Cara Therapeutics Inc | Cara Therapeutics Inc | 2023-08-31 | Removed / first absent |
| Axsome Therapeutics Inc | Axsome Therapeutics Inc | 2024-08-31 | Removed / first absent |
| Viking Therapeutics Inc | Viking Therapeutics Inc | 2024-08-31 | Removed / first absent |
| Cymabay Therapeutics Inc | Cymabay Therapeutics Inc | 2024-05-31 | Removed / first absent |
| Geron Corp | Geron Corp | 2025-02-28 | Removed / first absent |
| Aclaris Therapeutics Inc | Aclaris Therapeutics Inc | 2024-02-29 | Removed / first absent |
| Corcept Therapeutics Inc | Corcept Therapeutics Inc | 2025-02-28 | Removed / first absent |
| Arvinas Inc | Arvinas Inc | 2025-02-28 | Removed / first absent |
| Gritstone Bio Inc | Gritstone Bio Inc | 2023-08-31 | Removed / first absent |
| Pds Biotechnology Corp | Pds Biotechnology Corp | 2024-02-29 | Removed / first absent |
| Fulcrum Therapeutics Inc | Fulcrum Therapeutics Inc | 2023-08-31 | Removed / first absent |
| 89bio Inc | 89bio Inc | 2025-02-28 | Removed / first absent |
| Pliant Therapeutics Inc | Pliant Therapeutics Inc | 2025-08-31 | Removed / first absent |
| Bioatla Inc | Bioatla Inc | 2023-08-31 | Removed / first absent |
| Atea Pharmaceuticals Inc | Atea Pharmaceuticals Inc | 2025-02-28 | Removed / first absent |
| Ventyx Biosciences Inc | Ventyx Biosciences Inc | 2024-02-29 | Removed / first absent |
| Roivant Sciences Ltd | Roivant Sciences Ltd | 2023-08-31 | Removed / first absent |
| Arcellx Inc | Arcellx Inc | 2025-02-28 | Removed / first absent |
| Atai Life Sciences Nv | Atai Life Sciences Nv | 2023-08-31 | Removed / first absent |
| Amylyx Pharmaceuticals Inc | Amylyx Pharmaceuticals Inc | 2024-08-31 | Removed / first absent |
| N/A | N/A | 2026-02-28 | Removed / first absent |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Mirati Therapeutics Inc | Mirati Therapeutics Inc | 2023-08-31 | Removed / first absent |
| Global Blood Therapeutics Inc | Global Blood Therapeutics Inc | 2022-11-30 | Removed / first absent |
| Arrowhead Pharmaceuticals Inc | Arrowhead Pharmaceuticals Inc | 2023-08-31 | Removed / first absent |
| Ironwood Pharmaceuticals Inc | Ironwood Pharmaceuticals Inc | 2023-02-28 | Removed / first absent |
| Editas Medicine Inc | Editas Medicine Inc | 2023-02-28 | Removed / first absent |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Intellia Therapeutics Inc | Intellia Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Kura Oncology Inc | Kura Oncology Inc | 2025-02-28 | Removed / first absent |
| Biocryst Pharmaceuticals Inc | Biocryst Pharmaceuticals Inc | 2026-02-28 | Removed / first absent |
| Novavax Inc | Novavax Inc | 2023-08-31 | Removed / first absent |
| Eagle Pharmaceuticals Inc/de | Eagle Pharmaceuticals Inc/de | 2023-02-28 | Removed / first absent |
| Crispr Therapeutics Ag | Crispr Therapeutics Ag | 2023-02-28 | Removed / first absent |
| Ascendis Pharma A/s | Ascendis Pharma A/s | 2023-02-28 | Removed / first absent |
| Amarin Corp Plc | Amarin Corp Plc | 2023-02-28 | Removed / first absent |
| Adaptimmune Therapeutics Plc | Adaptimmune Therapeutics Plc | 2023-02-28 | Removed / first absent |
| Aurinia Pharmaceuticals Inc | Aurinia Pharmaceuticals Inc | 2026-02-28 | Removed / first absent |
| Concert Pharmaceuticals Inc | Concert Pharmaceuticals Inc | 2023-05-31 | Removed / first absent |
| Vbi Vaccines Inc | Vbi Vaccines Inc | 2023-02-28 | Removed / first absent |
| Ocugen Inc | Ocugen Inc | 2023-08-31 | Removed / first absent |
| Ideaya Biosciences Inc | Ideaya Biosciences Inc | 2023-02-28 | Removed / first absent |
| Vir Biotechnology Inc | Vir Biotechnology Inc | 2024-08-31 | Removed / first absent |
| Avidity Biosciences Inc | Avidity Biosciences Inc | 2026-02-28 | Removed / first absent |
| Repare Therapeutics Inc | Repare Therapeutics Inc | 2023-02-28 | Removed / first absent |
| I-mab | I-mab | 2024-02-29 | Removed / first absent |
| Vaxcyte Inc | Vaxcyte Inc | 2024-08-31 | Removed / first absent |
| Pmv Pharmaceuticals Inc | Pmv Pharmaceuticals Inc | 2023-02-28 | Removed / first absent |
| Adicet Bio Inc | Adicet Bio Inc | 2023-02-28 | Removed / first absent |
| Iteos Therapeutics Inc | Iteos Therapeutics Inc | 2025-08-31 | Removed / first absent |
| C4 Therapeutics Inc | C4 Therapeutics Inc | 2023-02-28 | Removed / first absent |
| 4d Molecular Therapeutics Inc | 4d Molecular Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Cullinan Oncology Inc | Cullinan Oncology Inc | 2023-02-28 | Removed / first absent |
| Viridian Therapeutics Inc | Viridian Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Essa Pharma Inc | Essa Pharma Inc | 2023-02-28 | Removed / first absent |
| Point Biopharma Global Inc | Point Biopharma Global Inc | 2024-02-29 | Removed / first absent |
| Tango Therapeutics Inc | Tango Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Icosavax Inc | Icosavax Inc | 2023-02-28 | Removed / first absent |
| Adagio Therapeutics Inc | Adagio Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Erasca Inc | Erasca Inc | 2023-02-28 | Removed / first absent |
| Nuvalent Inc | Nuvalent Inc | 2023-02-28 | Removed / first absent |
| Bicycle Therapeutics Plc | Bicycle Therapeutics Plc | 2023-02-28 | Removed / first absent |
| Rallybio Corp | Rallybio Corp | 2023-02-28 | Removed / first absent |
| Centessa Pharmaceuticals Plc | Centessa Pharmaceuticals Plc | 2023-02-28 | Removed / first absent |
| Eqrx Inc | Eqrx Inc | 2023-11-30 | Removed / first absent |
| Hillevax Inc | Hillevax Inc | 2024-02-29 | Removed / first absent |
| Moonlake Immunotherapeutics | Moonlake Immunotherapeutics | 2023-02-28 | Removed / first absent |
| Tonix Pharmaceuticals Holding Corp | Tonix Pharmaceuticals Holding Corp | 2022-08-31 | Removed / first absent |
| Ionis Pharmaceuticals Inc | Ionis Pharmaceuticals Inc | 2023-02-28 | Removed / first absent |
| Allakos Inc | Allakos Inc | 2022-08-31 | Removed / first absent |
| Checkpoint Therapeutics Inc | Checkpoint Therapeutics Inc | 2022-08-31 | Removed / first absent |
| Insmed Inc | Insmed Inc | 2022-08-31 | Removed / first absent |
| Opko Health Inc | Opko Health Inc | 2023-08-31 | Removed / first absent |
| Rigel Pharmaceuticals Inc | Rigel Pharmaceuticals Inc | 2023-02-28 | Removed / first absent |
| Agenus Inc | Agenus Inc | 2023-08-31 | Removed / first absent |
| Surface Oncology Inc | Surface Oncology Inc | 2022-08-31 | Removed / first absent |
| Kalvista Pharmaceuticals Inc | Kalvista Pharmaceuticals Inc | 2023-02-28 | Removed / first absent |
| Autolus Therapeutics Plc | Autolus Therapeutics Plc | 2023-02-28 | Removed / first absent |
| Aeglea Biotherapeutics Inc | Aeglea Biotherapeutics Inc | 2022-08-31 | Removed / first absent |
| Arbutus Biopharma Corp | Arbutus Biopharma Corp | 2023-08-31 | Removed / first absent |
| Jounce Therapeutics Inc | Jounce Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Protagonist Therapeutics Inc | Protagonist Therapeutics Inc | 2026-02-28 | Removed / first absent |
| Gritstone Bio Inc | Gritstone Bio Inc | 2022-08-31 | Removed / first absent |
| Pds Biotechnology Corp | Pds Biotechnology Corp | 2022-08-31 | Removed / first absent |
| Vaxart Inc | Vaxart Inc | 2023-02-28 | Removed / first absent |
| Atossa Therapeutics Inc | Atossa Therapeutics Inc | 2022-08-31 | Removed / first absent |
| Uniqure Nv | Uniqure Nv | 2023-02-28 | Removed / first absent |
| Proqr Therapeutics Nv | Proqr Therapeutics Nv | 2022-08-31 | Removed / first absent |
| Oyster Point Pharma Inc | Oyster Point Pharma Inc | 2022-08-31 | Removed / first absent |
| Tonix Pharmaceuticals Holding Corp | Tonix Pharmaceuticals Holding Corp | 2022-05-31 | Removed / first absent |
| Myovant Sciences Ltd | Myovant Sciences Ltd | 2022-08-31 | Removed / first absent |
| Beyondspring Inc | Beyondspring Inc | 2022-08-31 | Removed / first absent |
| Merus Nv | Merus Nv | 2023-08-31 | Removed / first absent |
| Kronos Bio Inc | Kronos Bio Inc | 2023-02-28 | Removed / first absent |
| Bellus Health Inc | Bellus Health Inc | 2023-08-31 | Removed / first absent |
| Mimedx Group Inc | Mimedx Group Inc | 2023-02-28 | Removed / first absent |
| Cogent Biosciences Inc | Cogent Biosciences Inc | 2023-08-31 | Removed / first absent |
| Prometheus Biosciences Inc | Prometheus Biosciences Inc | 2023-08-31 | Removed / first absent |
| Recursion Pharmaceuticals Inc | Recursion Pharmaceuticals Inc | 2024-02-29 | Removed / first absent |
| Instil Bio Inc | Instil Bio Inc | 2023-02-28 | Removed / first absent |
| Impel Neuropharma Inc | Impel Neuropharma Inc | 2022-08-31 | Removed / first absent |
| Longeveron Inc | Longeveron Inc | 2022-08-31 | Removed / first absent |
| Imago Biosciences Inc | Imago Biosciences Inc | 2023-02-28 | Removed / first absent |
| Compass Pathways Plc | Compass Pathways Plc | 2023-08-31 | Removed / first absent |
| Aadi Bioscience Inc | Aadi Bioscience Inc | 2024-02-29 | Removed / first absent |
| Lianbio | Lianbio | 2023-02-28 | Removed / first absent |
| Innate Pharma Sa | Innate Pharma Sa | 2022-08-31 | Removed / first absent |
| Effector Therapeutics Inc | Effector Therapeutics Inc | 2022-08-31 | Removed / first absent |
| Sab Biotherapeutics Inc | Sab Biotherapeutics Inc | 2022-08-31 | Removed / first absent |
| Valneva Se | Valneva Se | 2022-08-31 | Removed / first absent |
| Sage Therapeutics Inc | Sage Therapeutics Inc | 2024-02-29 | Removed / first absent |
| Syndax Pharmaceuticals Inc | Syndax Pharmaceuticals Inc | 2025-02-28 | Removed / first absent |
| Iovance Biotherapeutics Inc | Iovance Biotherapeutics Inc | 2023-02-28 | Removed / first absent |
| Amicus Therapeutics Inc | Amicus Therapeutics Inc | 2023-02-28 | Removed / first absent |
| G1 Therapeutics Inc | G1 Therapeutics Inc | 2022-02-28 | Removed / first absent |
| Atara Biotherapeutics Inc | Atara Biotherapeutics Inc | 2022-08-31 | Removed / first absent |
| Macrogenics Inc | Macrogenics Inc | 2022-08-31 | Removed / first absent |
| Immunogen Inc | Immunogen Inc | 2023-08-31 | Removed / first absent |
| Tg Therapeutics Inc | Tg Therapeutics Inc | 2022-02-28 | Removed / first absent |
| Y-mabs Therapeutics Inc | Y-mabs Therapeutics Inc | 2022-08-31 | Removed / first absent |
| Orchard Therapeutics Plc | Orchard Therapeutics Plc | 2022-02-28 | Removed / first absent |
| Adverum Biotechnologies Inc | Adverum Biotechnologies Inc | 2022-02-28 | Removed / first absent |
| Eiger Biopharmaceuticals Inc | Eiger Biopharmaceuticals Inc | 2022-02-28 | Removed / first absent |
| Savara Inc | Savara Inc | 2022-02-28 | Removed / first absent |
| Stoke Therapeutics Inc | Stoke Therapeutics Inc | 2024-02-29 | Removed / first absent |
| Arcturus Therapeutics Holdings Inc | Arcturus Therapeutics Holdings Inc | 2023-02-28 | Removed / first absent |
| Marker Therapeutics Inc | Marker Therapeutics Inc | 2022-02-28 | Removed / first absent |
| Kadmon Holdings Inc | Kadmon Holdings Inc | 2021-11-30 | Removed / first absent |
| Organogenesis Holdings Inc | Organogenesis Holdings Inc | 2023-02-28 | Removed / first absent |
| Infinity Pharmaceuticals Inc | Infinity Pharmaceuticals Inc | 2022-08-31 | Removed / first absent |
| Kodiak Sciences Inc | Kodiak Sciences Inc | 2023-08-31 | Removed / first absent |
| Alpine Immune Sciences Inc | Alpine Immune Sciences Inc | 2022-08-31 | Removed / first absent |
| Inmune Bio Inc | Inmune Bio Inc | 2022-08-31 | Removed / first absent |
| Vistagen Therapeutics Inc | Vistagen Therapeutics Inc | 2022-08-31 | Removed / first absent |
| Rapt Therapeutics Inc | Rapt Therapeutics Inc | 2024-08-31 | Removed / first absent |
| Meiragtx Holdings Plc | Meiragtx Holdings Plc | 2022-02-28 | Removed / first absent |
| Aveo Pharmaceuticals Inc | Aveo Pharmaceuticals Inc | 2022-08-31 | Removed / first absent |
| Keros Therapeutics Inc | Keros Therapeutics Inc | 2026-02-28 | Removed / first absent |
| Applied Molecular Transport Inc | Applied Molecular Transport Inc | 2022-08-31 | Removed / first absent |
| Forte Biosciences Inc | Forte Biosciences Inc | 2022-02-28 | Removed / first absent |
| Cardiff Oncology Inc | Cardiff Oncology Inc | 2022-08-31 | Removed / first absent |
| Annexon Inc | Annexon Inc | 2022-08-31 | Removed / first absent |
| Alx Oncology Holdings Inc | Alx Oncology Holdings Inc | 2024-02-29 | Removed / first absent |
| Cerevel Therapeutics Holdings Inc | Cerevel Therapeutics Holdings Inc | 2024-08-31 | Removed / first absent |
| Praxis Precision Medicines Inc | Praxis Precision Medicines Inc | 2022-08-31 | Removed / first absent |
| Bioatla Inc | Bioatla Inc | 2022-08-31 | Removed / first absent |
| Spruce Biosciences Inc | Spruce Biosciences Inc | 2022-02-28 | Removed / first absent |
| Gemini Therapeutics Inc | Gemini Therapeutics Inc | 2022-02-28 | Removed / first absent |
| Sensei Biotherapeutics Inc | Sensei Biotherapeutics Inc | 2022-02-28 | Removed / first absent |
| Clene Inc | Clene Inc | 2022-08-31 | Removed / first absent |
| Immutep Ltd | Immutep Ltd | 2022-08-31 | Removed / first absent |
| Adc Therapeutics Sa | Adc Therapeutics Sa | 2023-02-28 | Removed / first absent |
| Taiwan Liposome Co Ltd | Taiwan Liposome Co Ltd | 2021-11-30 | Removed / first absent |
| Bluebird Bio Inc | Bluebird Bio Inc | 2022-02-28 | Removed / first absent |
| Insmed Inc | Insmed Inc | 2021-08-31 | Removed / first absent |
| Regenxbio Inc | Regenxbio Inc | 2023-08-31 | Removed / first absent |
| Radius Health Inc | Radius Health Inc | 2022-08-31 | Removed / first absent |
| Esperion Therapeutics Inc | Esperion Therapeutics Inc | 2022-02-28 | Removed / first absent |
| Sangamo Therapeutics Inc | Sangamo Therapeutics Inc | 2022-02-28 | Removed / first absent |
| Ziopharm Oncology Inc | Ziopharm Oncology Inc | 2021-08-31 | Removed / first absent |
| Cytomx Therapeutics Inc | Cytomx Therapeutics Inc | 2022-08-31 | Removed / first absent |
| Geron Corp | Geron Corp | 2022-08-31 | Removed / first absent |
| Inovio Pharmaceuticals Inc | Inovio Pharmaceuticals Inc | 2022-02-28 | Removed / first absent |
| Aldeyra Therapeutics Inc | Aldeyra Therapeutics Inc | 2024-02-29 | Removed / first absent |
| Verastem Inc | Verastem Inc | 2022-02-28 | Removed / first absent |
| Eagle Pharmaceuticals Inc/de | Eagle Pharmaceuticals Inc/de | 2021-08-31 | Removed / first absent |
| Cytokinetics Inc | Cytokinetics Inc | 2023-08-31 | Removed / first absent |
| Arcus Biosciences Inc | Arcus Biosciences Inc | 2026-02-28 | Removed / first absent |
| Nucana Plc | Nucana Plc | 2021-08-31 | Removed / first absent |
| Seres Therapeutics Inc | Seres Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Aptinyx Inc | Aptinyx Inc | 2021-08-31 | Removed / first absent |
| Celldex Therapeutics Inc | Celldex Therapeutics Inc | 2021-08-31 | Removed / first absent |
| Selecta Biosciences Inc | Selecta Biosciences Inc | 2022-02-28 | Removed / first absent |
| Chimerix Inc | Chimerix Inc | 2022-02-28 | Removed / first absent |
| Fortress Biotech Inc | Fortress Biotech Inc | 2022-08-31 | Removed / first absent |
| Kezar Life Sciences Inc | Kezar Life Sciences Inc | 2024-02-29 | Removed / first absent |
| Immunic Inc | Immunic Inc | 2022-08-31 | Removed / first absent |
| Vaxart Inc | Vaxart Inc | 2021-08-31 | Removed / first absent |
| Altimmune Inc | Altimmune Inc | 2024-02-29 | Removed / first absent |
| Mirum Pharmaceuticals Inc | Mirum Pharmaceuticals Inc | 2022-02-28 | Removed / first absent |
| Prothena Corp Plc | Prothena Corp Plc | 2026-02-28 | Removed / first absent |
| Kiniksa Pharmaceuticals Ltd | Kiniksa Pharmaceuticals Ltd | 2022-02-28 | Removed / first absent |
| Immunovant Inc | Immunovant Inc | 2024-02-29 | Removed / first absent |
| 89bio Inc | 89bio Inc | 2022-08-31 | Removed / first absent |
| Ac Immune Sa | Ac Immune Sa | 2022-02-28 | Removed / first absent |
| Forma Therapeutics Holdings Inc | Forma Therapeutics Holdings Inc | 2022-11-30 | Removed / first absent |
| Protara Therapeutics Inc | Protara Therapeutics Inc | 2021-08-31 | Removed / first absent |
| Allovir Inc | Allovir Inc | 2023-08-31 | Removed / first absent |
| Travere Therapeutics Inc | Travere Therapeutics Inc | 2024-08-31 | Removed / first absent |
| Legend Biotech Corp | Legend Biotech Corp | 2022-02-28 | Removed / first absent |
| Gamida Cell Ltd | Gamida Cell Ltd | 2022-02-28 | Removed / first absent |
| Kamada Ltd | Kamada Ltd | 2021-08-31 | Removed / first absent |
| Affimed Nv | Affimed Nv | 2023-08-31 | Removed / first absent |
| Chinook Therapeutics Inc | Chinook Therapeutics Inc | 2023-08-31 | Removed / first absent |
| Inflarx Nv | Inflarx Nv | 2021-02-28 | Removed / first absent |
| Blueprint Medicines Corp | Blueprint Medicines Corp | 2021-02-28 | Removed / first absent |
| Arrowhead Pharmaceuticals Inc | Arrowhead Pharmaceuticals Inc | 2021-02-28 | Removed / first absent |
| Anaptysbio Inc | Anaptysbio Inc | 2026-02-28 | Removed / first absent |
| Heron Therapeutics Inc | Heron Therapeutics Inc | 2021-02-28 | Removed / first absent |
| Karyopharm Therapeutics Inc | Karyopharm Therapeutics Inc | 2021-02-28 | Removed / first absent |
| Avrobio Inc | Avrobio Inc | 2021-08-31 | Removed / first absent |
| Emergent Biosolutions Inc | Emergent Biosolutions Inc | 2023-08-31 | Removed / first absent |
| Y-mabs Therapeutics Inc | Y-mabs Therapeutics Inc | 2021-02-28 | Removed / first absent |
| Scholar Rock Holding Corp | Scholar Rock Holding Corp | 2022-08-31 | Removed / first absent |
| Aduro Biotech Inc | Aduro Biotech Inc | 2020-11-30 | Removed / first absent |
| Molecular Templates Inc | Molecular Templates Inc | 2022-02-28 | Removed / first absent |
| Ardelyx Inc | Ardelyx Inc | 2021-02-28 | Removed / first absent |
| Magenta Therapeutics Inc | Magenta Therapeutics Inc | 2022-08-31 | Removed / first absent |
| Adaptimmune Therapeutics Plc | Adaptimmune Therapeutics Plc | 2022-02-28 | Removed / first absent |
| Aurinia Pharmaceuticals Inc | Aurinia Pharmaceuticals Inc | 2022-02-28 | Removed / first absent |
| Syros Pharmaceuticals Inc | Syros Pharmaceuticals Inc | 2022-02-28 | Removed / first absent |
| American Realty Capital Trust | American Realty Capital Trust | 2021-02-28 | Removed / first absent |
| CEL Sci Corp | CEL Sci Corp | 2021-08-31 | Removed / first absent |
| Mei Pharma Inc | Mei Pharma Inc | 2022-08-31 | Removed / first absent |
| Kodiak Sciences Inc | Kodiak Sciences Inc | 2021-02-28 | Removed / first absent |
| Iveric Bio Inc | Iveric Bio Inc | 2023-08-31 | Removed / first absent |
| Aravive Inc | Aravive Inc | 2021-02-28 | Removed / first absent |
| Bioxcel Therapeutics INC | Bioxcel Therapeutics INC | 2023-08-31 | Removed / first absent |
| Proqr Therapeutics Nv | Proqr Therapeutics Nv | 2021-08-31 | Removed / first absent |
| VIR Biotechnology Inc | VIR Biotechnology Inc | 2022-02-28 | Removed / first absent |
| Viela Bio Inc | Viela Bio Inc | 2021-05-31 | Removed / first absent |
| Arcutis Biotherapeutics Incorporation | Arcutis Biotherapeutics Incorporation | 2023-08-31 | Removed / first absent |
| Affimed Nv | Affimed Nv | 2020-11-30 | Removed / first absent |
| Inflarx Nv | Inflarx Nv | 2020-11-30 | Removed / first absent |
| Bluebird Bio Inc | Bluebird Bio Inc | 2020-08-31 | Removed / first absent |
| Portola Pharmaceuticals Inc | Portola Pharmaceuticals Inc | 2020-08-31 | Removed / first absent |
| Intercept Pharmaceuticals Inc | Intercept Pharmaceuticals Inc | 2023-11-30 | Removed / first absent |
| Ironwood Pharmaceuticals Inc | Ironwood Pharmaceuticals Inc | 2021-08-31 | Removed / first absent |
| Coherus Biosciences Inc | Coherus Biosciences Inc | 2022-08-31 | Removed / first absent |
| Catalyst Pharmaceuticals Inc | Catalyst Pharmaceuticals Inc | 2024-08-31 | Removed / first absent |
| Rocket Pharmaceuticals Inc | Rocket Pharmaceuticals Inc | 2023-08-31 | Removed / first absent |
| Cytomx Therapeutics Inc | Cytomx Therapeutics Inc | 2020-08-31 | Removed / first absent |
| Kalvista Pharmaceuticals Inc | Kalvista Pharmaceuticals Inc | 2021-02-28 | Removed / first absent |
| Zymeworks Inc | Zymeworks Inc | 2022-02-28 | Removed / first absent |
| Replimune Group Inc | Replimune Group Inc | 2026-02-28 | Removed / first absent |
| Alector Inc | Alector Inc | 2025-08-31 | Removed / first absent |
| Akero Therapeutics Inc | Akero Therapeutics Inc | 2026-02-28 | Removed / first absent |
| Karuna Therapeutics Inc | Karuna Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Xoma Corp | Xoma Corp | 2021-02-28 | Removed / first absent |
| Xbiotech Inc | Xbiotech Inc | 2022-08-31 | Removed / first absent |
| Cortexyme Inc | Cortexyme Inc | 2022-02-28 | Removed / first absent |
| Springworks Therapeutics Inc | Springworks Therapeutics Inc | 2024-08-31 | Removed / first absent |
| Frequency Therapeutics Inc | Frequency Therapeutics Inc | 2022-02-28 | Removed / first absent |
| Aprea Therapeutics Inc | Aprea Therapeutics Inc | 2021-08-31 | Removed / first absent |
| Oyster Point Pharma Inc | Oyster Point Pharma Inc | 2021-02-28 | Removed / first absent |
| Merus Nv | Merus Nv | 2021-02-28 | Removed / first absent |
| United Therapeutics Corp | United Therapeutics Corp | 2021-02-28 | Removed / first absent |
| Agios Pharmaceuticals Inc | Agios Pharmaceuticals Inc | 2020-02-29 | Removed / first absent |
| Acadia Pharmaceuticals Inc | Acadia Pharmaceuticals Inc | 2020-02-29 | Removed / first absent |
| Puma Biotechnology Inc | Puma Biotechnology Inc | 2022-02-28 | Removed / first absent |
| Acorda Therapeutics Inc | Acorda Therapeutics Inc | 2020-02-29 | Removed / first absent |
| Allakos Inc | Allakos Inc | 2021-02-28 | Removed / first absent |
| Acceleron Pharma Inc | Acceleron Pharma Inc | 2021-02-28 | Removed / first absent |
| Arena Pharmaceuticals Inc | Arena Pharmaceuticals Inc | 2022-02-28 | Removed / first absent |
| Ra Pharmaceuticals Inc | Ra Pharmaceuticals Inc | 2020-02-29 | Removed / first absent |
| Mirati Therapeutics Inc | Mirati Therapeutics Inc | 2021-02-28 | Removed / first absent |
| Apellis Pharmaceuticals Inc | Apellis Pharmaceuticals Inc | 2022-02-28 | Removed / first absent |
| Halozyme Therapeutics Inc | Halozyme Therapeutics Inc | 2020-02-29 | Removed / first absent |
| Eidos Therapeutics Inc | Eidos Therapeutics Inc | 2021-02-28 | Removed / first absent |
| Corbus Pharmaceuticals Holding | Corbus Pharmaceuticals Holding | 2020-02-29 | Removed / first absent |
| Principia Biopharma Inc | Principia Biopharma Inc | 2020-11-30 | Removed / first absent |
| Fibrogen Inc | Fibrogen Inc | 2023-08-31 | Removed / first absent |
| Global Blood Therapeutics Inc | Global Blood Therapeutics Inc | 2022-02-28 | Removed / first absent |
| Immunomedics Inc | Immunomedics Inc | 2020-08-31 | Removed / first absent |
| Ptc Therapeutics Inc | Ptc Therapeutics Inc | 2023-02-28 | Removed / first absent |
| Deciphera Pharmaceuticals Inc | Deciphera Pharmaceuticals Inc | 2021-02-28 | Removed / first absent |
| Madrigal Pharmaceuticals Inc | Madrigal Pharmaceuticals Inc | 2022-02-28 | Removed / first absent |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2021-08-31 | Removed / first absent |
| Anaptysbio Inc | Anaptysbio Inc | 2020-02-29 | Removed / first absent |
| Dicerna Pharmaceuticals Inc | Dicerna Pharmaceuticals Inc | 2022-02-28 | Removed / first absent |
| G1 Therapeutics Inc | G1 Therapeutics Inc | 2021-02-28 | Removed / first absent |
| Epizyme Inc | Epizyme Inc | 2021-02-28 | Removed / first absent |
| Arqule Inc | Arqule Inc | 2020-02-29 | Removed / first absent |
| Rhythm Pharmaceuticals Inc | Rhythm Pharmaceuticals Inc | 2020-02-29 | Removed / first absent |
| Cara Therapeutics Inc | Cara Therapeutics Inc | 2020-02-29 | Removed / first absent |
| Macrogenics Inc | Macrogenics Inc | 2020-08-31 | Removed / first absent |
| Kura Oncology Inc | Kura Oncology Inc | 2021-02-28 | Removed / first absent |
| Voyager Therapeutics Inc | Voyager Therapeutics Inc | 2021-08-31 | Removed / first absent |
| Vericel Corp | Vericel Corp | 2022-02-28 | Removed / first absent |
| Achillion Pharmaceuticals Inc | Achillion Pharmaceuticals Inc | 2020-02-29 | Removed / first absent |
| Progenics Pharmaceuticals Inc | Progenics Pharmaceuticals Inc | 2020-02-29 | Removed / first absent |
| Amag Pharmaceuticals Inc | Amag Pharmaceuticals Inc | 2020-02-29 | Removed / first absent |
| Immunogen Inc | Immunogen Inc | 2021-02-28 | Removed / first absent |
| Viking Therapeutics Inc | Viking Therapeutics Inc | 2022-08-31 | Removed / first absent |
| Chemocentryx Inc | Chemocentryx Inc | 2022-11-30 | Removed / first absent |
| Rigel Pharmaceuticals Inc | Rigel Pharmaceuticals Inc | 2021-02-28 | Removed / first absent |
| Mannkind Corp | Mannkind Corp | 2020-02-29 | Removed / first absent |
| Agenus Inc | Agenus Inc | 2020-08-31 | Removed / first absent |
| Assembly Biosciences Inc | Assembly Biosciences Inc | 2021-08-31 | Removed / first absent |
| Glycomimetics Inc | Glycomimetics Inc | 2020-08-31 | Removed / first absent |
| Enanta Pharmaceuticals Inc | Enanta Pharmaceuticals Inc | 2025-08-31 | Removed / first absent |
| Anika Therapeutics Inc | Anika Therapeutics Inc | 2020-02-29 | Removed / first absent |
| Ligand Pharmaceuticals Inc | Ligand Pharmaceuticals Inc | 2023-02-28 | Removed / first absent |
| Emergent Biosolutions Inc | Emergent Biosolutions Inc | 2020-02-29 | Removed / first absent |
| Krystal Biotech Inc | Krystal Biotech Inc | 2024-02-29 | Removed / first absent |
| Gossamer Bio Inc | Gossamer Bio Inc | 2022-08-31 | Removed / first absent |
| Akcea Therapeutics Inc | Akcea Therapeutics Inc | 2020-11-30 | Removed / first absent |
| Pdl Biopharma Inc | Pdl Biopharma Inc | 2021-02-28 | Removed / first absent |
| Y-mabs Therapeutics Inc | Y-mabs Therapeutics Inc | 2020-02-29 | Removed / first absent |
| Scholar Rock Holding Corp | Scholar Rock Holding Corp | 2020-02-29 | Removed / first absent |
| Minerva Neurosciences Inc | Minerva Neurosciences Inc | 2020-02-29 | Removed / first absent |
| Aduro Biotech Inc | Aduro Biotech Inc | 2020-02-29 | Removed / first absent |
| Orchard Therapeutics Plc | Orchard Therapeutics Plc | 2020-08-31 | Removed / first absent |
| Xenon Pharmaceuticals Inc | Xenon Pharmaceuticals Inc | 2020-02-29 | Removed / first absent |
| Magenta Therapeutics Inc | Magenta Therapeutics Inc | 2020-02-29 | Removed / first absent |
| Medicinova Inc | Medicinova Inc | 2021-02-28 | Removed / first absent |
| Concert Pharmaceuticals Inc | Concert Pharmaceuticals Inc | 2021-08-31 | Removed / first absent |
| Savara Inc | Savara Inc | 2020-02-29 | Removed / first absent |
| N/A | N/A | 2020-05-31 | Removed / first absent |
| Marker Therapeutics Inc | Marker Therapeutics Inc | 2020-02-29 | Removed / first absent |
| Phasebio Pharmaceuticals Inc | Phasebio Pharmaceuticals Inc | 2020-02-29 | Removed / first absent |
| Athersys Inc | Athersys Inc | 2020-02-29 | Removed / first absent |
| Albireo Pharma Inc | Albireo Pharma Inc | 2023-05-31 | Removed / first absent |
| Constellation Pharmaceuticals | Constellation Pharmaceuticals | 2021-08-31 | Removed / first absent |
| Uniqure Nv | Uniqure Nv | 2021-08-31 | Removed / first absent |
| Kiniksa Pharmaceuticals Ltd | Kiniksa Pharmaceuticals Ltd | 2020-02-29 | Removed / first absent |
| Proqr Therapeutics Nv | Proqr Therapeutics Nv | 2020-02-29 | Removed / first absent |
| Meiragtx Holdings Plc | Meiragtx Holdings Plc | 2021-02-28 | Removed / first absent |
| Urogen Pharma Ltd | Urogen Pharma Ltd | 2020-08-31 | Removed / first absent |
| Morphosys Ag | Morphosys Ag | 2022-02-28 | Removed / first absent |
| Ac Immune Sa | Ac Immune Sa | 2020-02-29 | Removed / first absent |