IDNA additions & removals
Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.
Additions
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| ARCELLX INC CVR | ARCELLX INC CVR | 2026-04-30 | Added / first present |
| 1XAVM26 | XAV HEALTH CARE JUN26 | 2026-04-30 | Added / first present |
| VERTEX PHARMACEUTICALS INCORPORATED | VERTEX PHARMACEUTICALS INCORPORATED | 2026-01-31 | Added / first present |
| NEW TAIWAN DOLLAR | NEW TAIWAN DOLLAR | 2026-01-31 | Added / first present |
| CytomX Therapeutics Inc | CytomX Therapeutics Inc | 2026-01-31 | Added / first present |
| CRISPR Therapeutics AG | CRISPR Therapeutics AG | 2026-01-31 | Added / first present |
| Personalis Inc | Personalis Inc | 2026-01-31 | Added / first present |
| Corvus Pharmaceuticals Inc | Corvus Pharmaceuticals Inc | 2026-01-31 | Added / first present |
| Ocugen Inc | Ocugen Inc | 2026-01-31 | Added / first present |
| IDEAYA Biosciences Inc | IDEAYA Biosciences Inc | 2026-01-31 | Added / first present |
| Design Therapeutics Inc | Design Therapeutics Inc | 2026-01-31 | Added / first present |
| Nuvation Bio Inc | Nuvation Bio Inc | 2026-01-31 | Added / first present |
| Prime Medicine Inc | Prime Medicine Inc | 2026-01-31 | Added / first present |
| Alvotech SA | Alvotech SA | 2026-01-31 | Added / first present |
| VERASTEM, INC. | VERASTEM, INC. | 2026-01-31 | Added / first present |
| CARIS LIFE SCIENCES, INC. | CARIS LIFE SCIENCES, INC. | 2026-01-31 | Added / first present |
| GenFleet Therapeutics (Shanghai) Inc | GenFleet Therapeutics (Shanghai) Inc | 2026-01-31 | Added / first present |
| AbClon Inc. | AbClon Inc. | 2026-01-31 | Added / first present |
| Sunshine Lake Pharma Co Ltd | Sunshine Lake Pharma Co Ltd | 2026-01-31 | Added / first present |
| Guangzhou Innogen Pharmaceutical Group Co Ltd | Guangzhou Innogen Pharmaceutical Group Co Ltd | 2026-01-31 | Added / first present |
| 1XAVH26 | XAV HEALTH CARE MAR26 | 2026-01-31 | Added / first present |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2025-01-31 | Added / first present |
| Sangamo Therapeutics Inc | Sangamo Therapeutics Inc | 2025-01-31 | Added / first present |
| Kura Oncology Inc | Kura Oncology Inc | 2025-01-31 | Added / first present |
| Pacific Biosciences of California Inc | Pacific Biosciences of California Inc | 2025-01-31 | Added / first present |
| Celcuity Inc | Celcuity Inc | 2025-01-31 | Added / first present |
| ORIC Pharmaceuticals Inc | ORIC Pharmaceuticals Inc | 2025-01-31 | Added / first present |
| Immunome Inc | Immunome Inc | 2025-01-31 | Added / first present |
| Mereo Biopharma Group PLC | Mereo Biopharma Group PLC | 2025-01-31 | Added / first present |
| Verve Therapeutics Inc | Verve Therapeutics Inc | 2025-01-31 | Added / first present |
| Janux Therapeutics Inc | Janux Therapeutics Inc | 2025-01-31 | Added / first present |
| Cargo Therapeutics Inc | Cargo Therapeutics Inc | 2025-01-31 | Added / first present |
| Rigel Pharmaceuticals Inc | Rigel Pharmaceuticals Inc | 2025-01-31 | Added / first present |
| Ginkgo Bioworks Holdings Inc | Ginkgo Bioworks Holdings Inc | 2024-10-31 | Added / first present |
| Merck & Co Inc | Merck & Co Inc | 2024-01-31 | Added / first present |
| Gilead Sciences Inc | Gilead Sciences Inc | 2024-01-31 | Added / first present |
| Incyte Corp | Incyte Corp | 2024-01-31 | Added / first present |
| Sarepta Therapeutics Inc | Sarepta Therapeutics Inc | 2024-01-31 | Added / first present |
| Deciphera Pharmaceuticals Inc | Deciphera Pharmaceuticals Inc | 2024-01-31 | Added / first present |
| Geron Corp | Geron Corp | 2024-01-31 | Added / first present |
| Dynavax Technologies Corp | Dynavax Technologies Corp | 2024-01-31 | Added / first present |
| Novavax Inc | Novavax Inc | 2024-01-31 | Added / first present |
| REVOLUTION Medicines Inc | REVOLUTION Medicines Inc | 2024-01-31 | Added / first present |
| Nurix Therapeutics Inc | Nurix Therapeutics Inc | 2024-01-31 | Added / first present |
| 4D Molecular Therapeutics Inc | 4D Molecular Therapeutics Inc | 2024-01-31 | Added / first present |
| AbCellera Biologics Inc | AbCellera Biologics Inc | 2024-01-31 | Added / first present |
| Icosavax Inc | Icosavax Inc | 2024-01-31 | Added / first present |
| Arcellx Inc | Arcellx Inc | 2024-01-31 | Added / first present |
| OmniAb Inc | OmniAb Inc | 2024-01-31 | Added / first present |
| Bionano Genomics Inc | Bionano Genomics Inc | 2023-10-31 | Added / first present |
| Xencor Inc | Xencor Inc | 2023-01-31 | Added / first present |
| MacroGenics Inc | MacroGenics Inc | 2023-01-31 | Added / first present |
| Karyopharm Therapeutics Inc | Karyopharm Therapeutics Inc | 2023-01-31 | Added / first present |
| BioCryst Pharmaceuticals Inc | BioCryst Pharmaceuticals Inc | 2023-01-31 | Added / first present |
| Arbutus Biopharma Corp | Arbutus Biopharma Corp | 2023-01-31 | Added / first present |
| Ocugen Inc | Ocugen Inc | 2023-01-31 | Added / first present |
| Bionano Genomics Inc | Bionano Genomics Inc | 2023-01-31 | Added / first present |
| SpringWorks Therapeutics Inc | SpringWorks Therapeutics Inc | 2023-01-31 | Added / first present |
| Nkarta Inc | Nkarta Inc | 2023-01-31 | Added / first present |
| Adicet Bio Inc | Adicet Bio Inc | 2023-01-31 | Added / first present |
| Atea Pharmaceuticals Inc | Atea Pharmaceuticals Inc | 2023-01-31 | Added / first present |
| ImmunityBio Inc | ImmunityBio Inc | 2023-01-31 | Added / first present |
| Sana Biotechnology Inc | Sana Biotechnology Inc | 2023-01-31 | Added / first present |
| Caribou Biosciences Inc | Caribou Biosciences Inc | 2023-01-31 | Added / first present |
| Ginkgo Bioworks Holdings Inc | Ginkgo Bioworks Holdings Inc | 2023-01-31 | Added / first present |
| Prime Medicine Inc | Prime Medicine Inc | 2023-01-31 | Added / first present |
| OMNIAB INC | OMNIAB INC | 2023-01-31 | Added / first present |
| OMNIAB INC | OMNIAB INC | 2023-01-31 | Added / first present |
| Iovance Biotherapeutics Inc | Iovance Biotherapeutics Inc | 2022-01-31 | Added / first present |
| Coherus Biosciences Inc | Coherus Biosciences Inc | 2022-01-31 | Added / first present |
| Novavax Inc | Novavax Inc | 2022-01-31 | Added / first present |
| Gossamer Bio Inc | Gossamer Bio Inc | 2022-01-31 | Added / first present |
| Arcus Biosciences Inc | Arcus Biosciences Inc | 2022-01-31 | Added / first present |
| Cue Biopharma Inc | Cue Biopharma Inc | 2022-01-31 | Added / first present |
| NGM Biopharmaceuticals Inc | NGM Biopharmaceuticals Inc | 2022-01-31 | Added / first present |
| Beam Therapeutics Inc | Beam Therapeutics Inc | 2022-01-31 | Added / first present |
| Humanigen Inc | Humanigen Inc | 2022-01-31 | Added / first present |
| Maravai LifeSciences Holdings Inc | Maravai LifeSciences Holdings Inc | 2022-01-31 | Added / first present |
| Syros Pharmaceuticals Inc | Syros Pharmaceuticals Inc | 2021-07-31 | Added / first present |
| ImmunityBio Inc | ImmunityBio Inc | 2021-04-30 | Added / first present |
| Blueprint Medicines Corp | Blueprint Medicines Corp | 2021-01-31 | Added / first present |
| BioCryst Pharmaceuticals Inc | BioCryst Pharmaceuticals Inc | 2021-01-31 | Added / first present |
| Five Prime Therapeutics Inc | Five Prime Therapeutics Inc | 2021-01-31 | Added / first present |
| Molecular Templates Inc | Molecular Templates Inc | 2021-01-31 | Added / first present |
| Adaptimmune Therapeutics Plc | Adaptimmune Therapeutics Plc | 2021-01-31 | Added / first present |
| Syros Pharmaceuticals Inc | Syros Pharmaceuticals Inc | 2021-01-31 | Added / first present |
| Personalis Inc | Personalis Inc | 2021-01-31 | Added / first present |
| Arcturus Therapeutics Holdings Inc | Arcturus Therapeutics Holdings Inc | 2021-01-31 | Added / first present |
| TCR2 Therapeutics Inc | TCR2 Therapeutics Inc | 2021-01-31 | Added / first present |
| NantKwest Inc | NantKwest Inc | 2021-01-31 | Added / first present |
| IVERIC bio Inc | IVERIC bio Inc | 2021-01-31 | Added / first present |
| Vaxart Inc | Vaxart Inc | 2021-01-31 | Added / first present |
| Altimmune Inc | Altimmune Inc | 2021-01-31 | Added / first present |
| SpringWorks Therapeutics Inc | SpringWorks Therapeutics Inc | 2021-01-31 | Added / first present |
| RAPT Therapeutics Inc | RAPT Therapeutics Inc | 2021-01-31 | Added / first present |
| Aligos Therapeutics Inc | Aligos Therapeutics Inc | 2021-01-31 | Added / first present |
| Seagen Inc | Seagen Inc | 2020-10-31 | Added / first present |
| BIONTECH SE RTS EXP 14AUG20 | BIONTECH SE RTS EXP 14AUG20 | 2020-07-31 | Added / first present |
| Gilead Sciences Inc | Gilead Sciences Inc | 2020-01-31 | Added / first present |
| Karyopharm Therapeutics Inc | Karyopharm Therapeutics Inc | 2020-01-31 | Added / first present |
| Voyager Therapeutics Inc | Voyager Therapeutics Inc | 2020-01-31 | Added / first present |
| Twist Bioscience Corp | Twist Bioscience Corp | 2020-01-31 | Added / first present |
| Orchard Therapeutics plc | Orchard Therapeutics plc | 2020-01-31 | Added / first present |
| Translate Bio Inc | Translate Bio Inc | 2020-01-31 | Added / first present |
| Adverum Biotechnologies Inc | Adverum Biotechnologies Inc | 2020-01-31 | Added / first present |
| Bridgebio Pharma Inc | Bridgebio Pharma Inc | 2020-01-31 | Added / first present |
| Provention Bio Inc | Provention Bio Inc | 2020-01-31 | Added / first present |
| Constellation Pharmaceuticals Inc | Constellation Pharmaceuticals Inc | 2020-01-31 | Added / first present |
| Precision BioSciences Inc | Precision BioSciences Inc | 2020-01-31 | Added / first present |
| BioNTech SE | BioNTech SE | 2020-01-31 | Added / first present |
| Vir Biotechnology Inc | Vir Biotechnology Inc | 2020-01-31 | Added / first present |
Removals
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| 1XAVH26 | XAV HEALTH CARE MAR26 | 2026-04-30 | Removed / first absent |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2025-07-31 | Removed / first absent |
| Sangamo Therapeutics Inc | Sangamo Therapeutics Inc | 2025-07-31 | Removed / first absent |
| Celcuity Inc | Celcuity Inc | 2026-01-31 | Removed / first absent |
| ORIC Pharmaceuticals Inc | ORIC Pharmaceuticals Inc | 2026-01-31 | Removed / first absent |
| Immunome Inc | Immunome Inc | 2026-01-31 | Removed / first absent |
| Verve Therapeutics Inc | Verve Therapeutics Inc | 2025-07-31 | Removed / first absent |
| Cargo Therapeutics Inc | Cargo Therapeutics Inc | 2025-07-31 | Removed / first absent |
| Gilead Sciences Inc | Gilead Sciences Inc | 2025-01-31 | Removed / first absent |
| Sarepta Therapeutics Inc | Sarepta Therapeutics Inc | 2025-01-31 | Removed / first absent |
| Deciphera Pharmaceuticals Inc | Deciphera Pharmaceuticals Inc | 2024-07-31 | Removed / first absent |
| Geron Corp | Geron Corp | 2026-01-31 | Removed / first absent |
| Dynavax Technologies Corp | Dynavax Technologies Corp | 2025-01-31 | Removed / first absent |
| Nurix Therapeutics Inc | Nurix Therapeutics Inc | 2025-01-31 | Removed / first absent |
| 4D Molecular Therapeutics Inc | 4D Molecular Therapeutics Inc | 2025-07-31 | Removed / first absent |
| Icosavax Inc | Icosavax Inc | 2024-04-30 | Removed / first absent |
| Arcellx Inc | Arcellx Inc | 2026-04-30 | Removed / first absent |
| OmniAb Inc | OmniAb Inc | 2025-07-31 | Removed / first absent |
| Bionano Genomics Inc | Bionano Genomics Inc | 2024-01-31 | Removed / first absent |
| MacroGenics Inc | MacroGenics Inc | 2025-01-31 | Removed / first absent |
| Karyopharm Therapeutics Inc | Karyopharm Therapeutics Inc | 2024-01-31 | Removed / first absent |
| BioCryst Pharmaceuticals Inc | BioCryst Pharmaceuticals Inc | 2026-01-31 | Removed / first absent |
| Arbutus Biopharma Corp | Arbutus Biopharma Corp | 2024-01-31 | Removed / first absent |
| Ocugen Inc | Ocugen Inc | 2023-07-31 | Removed / first absent |
| Bionano Genomics Inc | Bionano Genomics Inc | 2023-10-31 | Removed / first absent |
| SpringWorks Therapeutics Inc | SpringWorks Therapeutics Inc | 2025-07-31 | Removed / first absent |
| Nkarta Inc | Nkarta Inc | 2023-07-31 | Removed / first absent |
| Adicet Bio Inc | Adicet Bio Inc | 2023-07-31 | Removed / first absent |
| Atea Pharmaceuticals Inc | Atea Pharmaceuticals Inc | 2024-01-31 | Removed / first absent |
| Sana Biotechnology Inc | Sana Biotechnology Inc | 2024-01-31 | Removed / first absent |
| Caribou Biosciences Inc | Caribou Biosciences Inc | 2024-07-31 | Removed / first absent |
| Ginkgo Bioworks Holdings Inc | Ginkgo Bioworks Holdings Inc | 2024-10-31 | Removed / first absent |
| Prime Medicine Inc | Prime Medicine Inc | 2024-01-31 | Removed / first absent |
| Coherus Biosciences Inc | Coherus Biosciences Inc | 2024-01-31 | Removed / first absent |
| Novavax Inc | Novavax Inc | 2023-01-31 | Removed / first absent |
| Gossamer Bio Inc | Gossamer Bio Inc | 2023-01-31 | Removed / first absent |
| Cue Biopharma Inc | Cue Biopharma Inc | 2022-07-31 | Removed / first absent |
| NGM Biopharmaceuticals Inc | NGM Biopharmaceuticals Inc | 2023-01-31 | Removed / first absent |
| Beam Therapeutics Inc | Beam Therapeutics Inc | 2026-01-31 | Removed / first absent |
| Humanigen Inc | Humanigen Inc | 2022-07-31 | Removed / first absent |
| Maravai LifeSciences Holdings Inc | Maravai LifeSciences Holdings Inc | 2023-01-31 | Removed / first absent |
| Syros Pharmaceuticals Inc | Syros Pharmaceuticals Inc | 2022-01-31 | Removed / first absent |
| ImmunityBio Inc | ImmunityBio Inc | 2022-01-31 | Removed / first absent |
| Blueprint Medicines Corp | Blueprint Medicines Corp | 2025-01-31 | Removed / first absent |
| BioCryst Pharmaceuticals Inc | BioCryst Pharmaceuticals Inc | 2022-01-31 | Removed / first absent |
| Five Prime Therapeutics Inc | Five Prime Therapeutics Inc | 2021-04-30 | Removed / first absent |
| Molecular Templates Inc | Molecular Templates Inc | 2022-01-31 | Removed / first absent |
| Adaptimmune Therapeutics Plc | Adaptimmune Therapeutics Plc | 2023-01-31 | Removed / first absent |
| Syros Pharmaceuticals Inc | Syros Pharmaceuticals Inc | 2021-04-30 | Removed / first absent |
| Personalis Inc | Personalis Inc | 2022-07-31 | Removed / first absent |
| Arcturus Therapeutics Holdings Inc | Arcturus Therapeutics Holdings Inc | 2026-01-31 | Removed / first absent |
| TCR2 Therapeutics Inc | TCR2 Therapeutics Inc | 2022-01-31 | Removed / first absent |
| NantKwest Inc | NantKwest Inc | 2021-04-30 | Removed / first absent |
| IVERIC bio Inc | IVERIC bio Inc | 2022-01-31 | Removed / first absent |
| Vaxart Inc | Vaxart Inc | 2023-01-31 | Removed / first absent |
| Altimmune Inc | Altimmune Inc | 2022-07-31 | Removed / first absent |
| SpringWorks Therapeutics Inc | SpringWorks Therapeutics Inc | 2022-01-31 | Removed / first absent |
| RAPT Therapeutics Inc | RAPT Therapeutics Inc | 2023-01-31 | Removed / first absent |
| Aligos Therapeutics Inc | Aligos Therapeutics Inc | 2022-07-31 | Removed / first absent |
| Seagen Inc | Seagen Inc | 2022-01-31 | Removed / first absent |
| BIONTECH SE RTS EXP 14AUG20 | BIONTECH SE RTS EXP 14AUG20 | 2020-10-31 | Removed / first absent |
| Gilead Sciences Inc | Gilead Sciences Inc | 2023-01-31 | Removed / first absent |
| Karyopharm Therapeutics Inc | Karyopharm Therapeutics Inc | 2021-01-31 | Removed / first absent |
| Voyager Therapeutics Inc | Voyager Therapeutics Inc | 2021-01-31 | Removed / first absent |
| Orchard Therapeutics plc | Orchard Therapeutics plc | 2021-01-31 | Removed / first absent |
| Translate Bio Inc | Translate Bio Inc | 2021-01-31 | Removed / first absent |
| Adverum Biotechnologies Inc | Adverum Biotechnologies Inc | 2021-01-31 | Removed / first absent |
| Bridgebio Pharma Inc | Bridgebio Pharma Inc | 2021-01-31 | Removed / first absent |
| Provention Bio Inc | Provention Bio Inc | 2021-01-31 | Removed / first absent |
| Constellation Pharmaceuticals Inc | Constellation Pharmaceuticals Inc | 2021-07-31 | Removed / first absent |
| Precision BioSciences Inc | Precision BioSciences Inc | 2022-07-31 | Removed / first absent |
| CRISPR Therapeutics AG | CRISPR Therapeutics AG | 2026-01-31 | Removed / first absent |
| Bristol-Myers Squibb Co | Bristol-Myers Squibb Co | 2020-01-31 | Removed / first absent |
| Seattle Genetics Inc | Seattle Genetics Inc | 2020-10-31 | Removed / first absent |
| Alnylam Pharmaceuticals Inc | Alnylam Pharmaceuticals Inc | 2020-01-31 | Removed / first absent |
| Sarepta Therapeutics Inc | Sarepta Therapeutics Inc | 2022-01-31 | Removed / first absent |
| Bluebird Bio Inc | Bluebird Bio Inc | 2022-07-31 | Removed / first absent |
| Portola Pharmaceuticals Inc | Portola Pharmaceuticals Inc | 2020-01-31 | Removed / first absent |
| Dermira Inc | Dermira Inc | 2020-04-30 | Removed / first absent |
| Acceleron Pharma Inc | Acceleron Pharma Inc | 2020-01-31 | Removed / first absent |
| Allogene Therapeutics Inc | Allogene Therapeutics Inc | 2024-01-31 | Removed / first absent |
| Mirati Therapeutics Inc | Mirati Therapeutics Inc | 2021-01-31 | Removed / first absent |
| FibroGen Inc | FibroGen Inc | 2023-01-31 | Removed / first absent |
| Iovance Biotherapeutics Inc | Iovance Biotherapeutics Inc | 2021-01-31 | Removed / first absent |
| Editas Medicine Inc | Editas Medicine Inc | 2025-01-31 | Removed / first absent |
| Invitae Corp | Invitae Corp | 2024-01-31 | Removed / first absent |
| Fate Therapeutics Inc | Fate Therapeutics Inc | 2024-01-31 | Removed / first absent |
| AnaptysBio Inc | AnaptysBio Inc | 2021-01-31 | Removed / first absent |
| Sangamo Therapeutics Inc | Sangamo Therapeutics Inc | 2023-07-31 | Removed / first absent |
| Dicerna Pharmaceuticals Inc | Dicerna Pharmaceuticals Inc | 2020-01-31 | Removed / first absent |
| Epizyme Inc | Epizyme Inc | 2020-01-31 | Removed / first absent |
| Intrexon Corp | Intrexon Corp | 2020-01-31 | Removed / first absent |
| NanoString Technologies Inc | NanoString Technologies Inc | 2022-01-31 | Removed / first absent |
| MacroGenics Inc | MacroGenics Inc | 2022-01-31 | Removed / first absent |
| Kura Oncology Inc | Kura Oncology Inc | 2021-01-31 | Removed / first absent |
| ZIOPHARM Oncology Inc | ZIOPHARM Oncology Inc | 2022-07-31 | Removed / first absent |
| CytomX Therapeutics Inc | CytomX Therapeutics Inc | 2022-07-31 | Removed / first absent |
| TG Therapeutics Inc | TG Therapeutics Inc | 2020-01-31 | Removed / first absent |
| Agenus Inc | Agenus Inc | 2023-01-31 | Removed / first absent |
| Inovio Pharmaceuticals Inc | Inovio Pharmaceuticals Inc | 2023-07-31 | Removed / first absent |
| Dynavax Technologies Corp | Dynavax Technologies Corp | 2020-01-31 | Removed / first absent |
| Ligand Pharmaceuticals Inc | Ligand Pharmaceuticals Inc | 2026-01-31 | Removed / first absent |
| Spark Therapeutics Inc | Spark Therapeutics Inc | 2020-01-31 | Removed / first absent |
| Homology Medicines Inc | Homology Medicines Inc | 2020-01-31 | Removed / first absent |