IBBQ additions & removals
Changes are observation-bounded: an addition is the first retained official snapshot containing a security after an earlier absence; a removal is its first retained absence. Baseline holdings receive no invented addition date.
Additions
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| Puma Biotechnology, Inc. | Puma Biotechnology, Inc. | 2026-02-28 | Added / first present |
| Coherus Oncology, Inc. | Coherus Oncology, Inc. | 2026-02-28 | Added / first present |
| CytomX Therapeutics, Inc. | CytomX Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Aclaris Therapeutics, Inc. | Aclaris Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Lifecore Biomedical, Inc. | Lifecore Biomedical, Inc. | 2026-02-28 | Added / first present |
| Gossamer Bio, Inc. | Gossamer Bio, Inc. | 2026-02-28 | Added / first present |
| Kodiak Sciences Inc. | Kodiak Sciences Inc. | 2026-02-28 | Added / first present |
| Eton Pharmaceuticals, Inc. | Eton Pharmaceuticals, Inc. | 2026-02-28 | Added / first present |
| Fulcrum Therapeutics, Inc. | Fulcrum Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Cabaletta Bio, Inc. | Cabaletta Bio, Inc. | 2026-02-28 | Added / first present |
| Black Diamond Therapeutics, Inc. | Black Diamond Therapeutics, Inc. | 2026-02-28 | Added / first present |
| NovaBridge Biosciences | NovaBridge Biosciences | 2026-02-28 | Added / first present |
| Kamada Ltd. | Kamada Ltd. | 2026-02-28 | Added / first present |
| Tenaya Therapeutics, Inc. | Tenaya Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Immuneering Corp. | Immuneering Corp. | 2026-02-28 | Added / first present |
| Invivyd, Inc. | Invivyd, Inc. | 2026-02-28 | Added / first present |
| Caribou Biosciences, Inc. | Caribou Biosciences, Inc. | 2026-02-28 | Added / first present |
| Quantum-Si Inc. | Quantum-Si Inc. | 2026-02-28 | Added / first present |
| Candel Therapeutics, Inc. | Candel Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Rani Therapeutics Holdings, Inc. | Rani Therapeutics Holdings, Inc. | 2026-02-28 | Added / first present |
| Ventyx Biosciences, Inc. | Ventyx Biosciences, Inc. | 2026-02-28 | Added / first present |
| Orchestra Biomed Holdings, Inc. | Orchestra Biomed Holdings, Inc. | 2026-02-28 | Added / first present |
| Sagimet Biosciences Inc. | Sagimet Biosciences Inc. | 2026-02-28 | Added / first present |
| Abivax S.A. | Abivax S.A. | 2026-02-28 | Added / first present |
| Contineum Therapeutics, Inc. | Contineum Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Septerna, Inc. | Septerna, Inc. | 2026-02-28 | Added / first present |
| Zenas Biopharma, Inc. | Zenas Biopharma, Inc. | 2026-02-28 | Added / first present |
| Pharvaris N.V. | Pharvaris N.V. | 2026-02-28 | Added / first present |
| GH Research PLC | GH Research PLC | 2026-02-28 | Added / first present |
| Bicara Therapeutics Inc. | Bicara Therapeutics Inc. | 2026-02-28 | Added / first present |
| MBX Biosciences, Inc. | MBX Biosciences, Inc. | 2026-02-28 | Added / first present |
| BioAge Labs, Inc. | BioAge Labs, Inc. | 2026-02-28 | Added / first present |
| Upstream Bio, Inc. | Upstream Bio, Inc. | 2026-02-28 | Added / first present |
| Sionna Therapeutics, Inc. | Sionna Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Maze Therapeutics, Inc. | Maze Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Aardvark Therapeutics, Inc. | Aardvark Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Caris Life Sciences, Inc. | Caris Life Sciences, Inc. | 2026-02-28 | Added / first present |
| RAPT Therapeutics, Inc. | RAPT Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Vor BioPharma Inc. | Vor BioPharma Inc. | 2026-02-28 | Added / first present |
| Indivior Pharmaceuticals, Inc. | Indivior Pharmaceuticals, Inc. | 2026-02-28 | Added / first present |
| AtaiBeckley Inc. | AtaiBeckley Inc. | 2026-02-28 | Added / first present |
| Definium Therapeutics, Inc. | Definium Therapeutics, Inc. | 2026-02-28 | Added / first present |
| Jyong Biotech Ltd. | Jyong Biotech Ltd. | 2026-02-28 | Added / first present |
| NOVOB CVR | Novo Nordisk A/S | 2026-02-28 | Added / first present |
| Invesco Government & Agency Portfolio | Invesco Government & Agency Portfolio | 2025-08-31 | Added / first present |
| Lyell Immunopharma, Inc. | Lyell Immunopharma, Inc. | 2025-08-31 | Added / first present |
| Mersana Therapeutics, Inc. | Mersana Therapeutics, Inc. | 2025-08-31 | Added / first present |
| Amarin Corp. PLC | Amarin Corp. PLC | 2025-05-31 | Added / first present |
| 10x Genomics, Inc. | 10x Genomics, Inc. | 2025-02-28 | Added / first present |
| Fate Therapeutics, Inc. | Fate Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Esperion Therapeutics, Inc. | Esperion Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Omeros Corp. | Omeros Corp. | 2025-02-28 | Added / first present |
| CorMedix Inc. | CorMedix Inc. | 2025-02-28 | Added / first present |
| Amneal Pharmaceuticals, Inc. | Amneal Pharmaceuticals, Inc. | 2025-02-28 | Added / first present |
| Enanta Pharmaceuticals, Inc. | Enanta Pharmaceuticals, Inc. | 2025-02-28 | Added / first present |
| Codexis, Inc. | Codexis, Inc. | 2025-02-28 | Added / first present |
| Sutro Biopharma, Inc. | Sutro Biopharma, Inc. | 2025-02-28 | Added / first present |
| Aquestive Therapeutics, Inc. | Aquestive Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Personalis, Inc. | Personalis, Inc. | 2025-02-28 | Added / first present |
| Stoke Therapeutics, Inc. | Stoke Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Mersana Therapeutics, Inc. | Mersana Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Corvus Pharmaceuticals, Inc. | Corvus Pharmaceuticals, Inc. | 2025-02-28 | Added / first present |
| Altimmune, Inc. | Altimmune, Inc. | 2025-02-28 | Added / first present |
| scPharmaceuticals Inc. | scPharmaceuticals Inc. | 2025-02-28 | Added / first present |
| Applied Therapeutics, Inc. | Applied Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Trevi Therapeutics, Inc. | Trevi Therapeutics, Inc. | 2025-02-28 | Added / first present |
| IGM Biosciences, Inc. | IGM Biosciences, Inc. | 2025-02-28 | Added / first present |
| Larimar Therapeutics, Inc. | Larimar Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Annexon, Inc. | Annexon, Inc. | 2025-02-28 | Added / first present |
| Nkarta, Inc. | Nkarta, Inc. | 2025-02-28 | Added / first present |
| Inozyme Pharma, Inc. | Inozyme Pharma, Inc. | 2025-02-28 | Added / first present |
| C4 Therapeutics, Inc. | C4 Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Foghorn Therapeutics Inc. | Foghorn Therapeutics Inc. | 2025-02-28 | Added / first present |
| Design Therapeutics, Inc. | Design Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Zevra Therapeutics, Inc. | Zevra Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Monte Rosa Therapeutics, Inc. | Monte Rosa Therapeutics, Inc. | 2025-02-28 | Added / first present |
| AbSci Corp. | AbSci Corp. | 2025-02-28 | Added / first present |
| Alpha Teknova, Inc. | Alpha Teknova, Inc. | 2025-02-28 | Added / first present |
| TScan Therapeutics, Inc. | TScan Therapeutics, Inc. | 2025-02-28 | Added / first present |
| COMPASS Pathways PLC | COMPASS Pathways PLC | 2025-02-28 | Added / first present |
| Astria Therapeutics, Inc. | Astria Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Climb Bio, Inc. | Climb Bio, Inc. | 2025-02-28 | Added / first present |
| 2seventy bio, Inc. | 2seventy bio, Inc. | 2025-02-28 | Added / first present |
| Pyxis Oncology, Inc. | Pyxis Oncology, Inc. | 2025-02-28 | Added / first present |
| Tyra Biosciences, Inc. | Tyra Biosciences, Inc. | 2025-02-28 | Added / first present |
| Entrada Therapeutics Inc. | Entrada Therapeutics Inc. | 2025-02-28 | Added / first present |
| Aura Biosciences, Inc. | Aura Biosciences, Inc. | 2025-02-28 | Added / first present |
| PepGen Inc. | PepGen Inc. | 2025-02-28 | Added / first present |
| Indivior PLC | Indivior PLC | 2025-02-28 | Added / first present |
| Mind Medicine (MindMed) Inc. | Mind Medicine (MindMed) Inc. | 2025-02-28 | Added / first present |
| Solid Biosciences Inc. | Solid Biosciences Inc. | 2025-02-28 | Added / first present |
| Acrivon Therapeutics, Inc. | Acrivon Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Alvotech | Alvotech | 2025-02-28 | Added / first present |
| Spyre Therapeutics, Inc. | Spyre Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Neumora Therapeutics, Inc. | Neumora Therapeutics, Inc. | 2025-02-28 | Added / first present |
| CG Oncology, Inc. | CG Oncology, Inc. | 2025-02-28 | Added / first present |
| Praxis Precision Medicines, Inc. | Praxis Precision Medicines, Inc. | 2025-02-28 | Added / first present |
| Neurogene Inc. | Neurogene Inc. | 2025-02-28 | Added / first present |
| CARGO Therapeutics, Inc. | CARGO Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Lexeo Therapeutics, Inc. | Lexeo Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Kyverna Therapeutics, Inc. | Kyverna Therapeutics, Inc. | 2025-02-28 | Added / first present |
| LENZ Therapeutics, Inc. | LENZ Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Q32 Bio Inc. | Q32 Bio Inc. | 2025-02-28 | Added / first present |
| ArriVent Biopharma, Inc. | ArriVent Biopharma, Inc. | 2025-02-28 | Added / first present |
| Rigel Pharmaceuticals, Inc. | Rigel Pharmaceuticals, Inc. | 2025-02-28 | Added / first present |
| Tectonic Therapeutic, Inc. | Tectonic Therapeutic, Inc. | 2025-02-28 | Added / first present |
| Inhibrx Biosciences, Inc. | Inhibrx Biosciences, Inc. | 2025-02-28 | Added / first present |
| Tempus AI, Inc. | Tempus AI, Inc. | 2025-02-28 | Added / first present |
| Cartesian Therapeutics, Inc. | Cartesian Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Rapport Therapeutics, Inc. | Rapport Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Oruka Therapeutics, Inc. | Oruka Therapeutics, Inc. | 2025-02-28 | Added / first present |
| Silence Therapeutics PLC | Silence Therapeutics PLC | 2025-02-28 | Added / first present |
| Tevogen Bio Holdings Inc. | Tevogen Bio Holdings Inc. | 2025-02-28 | Added / first present |
| Artiva Biotherapeutics, Inc. | Artiva Biotherapeutics, Inc. | 2025-02-28 | Added / first present |
| Alumis Inc. | Alumis Inc. | 2025-02-28 | Added / first present |
| NewAmsterdam Pharma Co. N.V. | NewAmsterdam Pharma Co. N.V. | 2025-02-28 | Added / first present |
| Mesoblast Ltd. | Mesoblast Ltd. | 2025-02-28 | Added / first present |
| Invesco Government & Agency Portfolio | Invesco Government & Agency Portfolio | 2024-11-30 | Added / first present |
| 23andMe Holding Co. | 23andMe Holding Co. | 2024-11-30 | Added / first present |
| OnKure Therapeutics, Inc. | OnKure Therapeutics, Inc. | 2024-11-30 | Added / first present |
| GRAIL Inc. | GRAIL Inc. | 2024-08-31 | Added / first present |
| Kiniksa Pharmaceuticals International, PLC | Kiniksa Pharmaceuticals International, PLC | 2024-08-31 | Added / first present |
| Avadel Pharmaceuticals PLC | Avadel Pharmaceuticals PLC | 2024-05-31 | Added / first present |
| Voyager Therapeutics, Inc. | Voyager Therapeutics, Inc. | 2024-02-29 | Added / first present |
| Vericel Corp. | Vericel Corp. | 2024-02-29 | Added / first present |
| Dynavax Technologies Corp. | Dynavax Technologies Corp. | 2024-02-29 | Added / first present |
| Y-mAbs Therapeutics, Inc. | Y-mAbs Therapeutics, Inc. | 2024-02-29 | Added / first present |
| KalVista Pharmaceuticals, Inc. | KalVista Pharmaceuticals, Inc. | 2024-02-29 | Added / first present |
| Autolus Therapeutics PLC | Autolus Therapeutics PLC | 2024-02-29 | Added / first present |
| Ovid Therapeutics Inc. | Ovid Therapeutics Inc. | 2024-02-29 | Added / first present |
| Savara Inc. | Savara Inc. | 2024-02-29 | Added / first present |
| Cabaletta Bio, Inc. | Cabaletta Bio, Inc. | 2024-02-29 | Added / first present |
| AC Immune S.A. | AC Immune S.A. | 2024-02-29 | Added / first present |
| ORIC Pharmaceuticals, Inc. | ORIC Pharmaceuticals, Inc. | 2024-02-29 | Added / first present |
| Fusion Pharmaceuticals Inc. | Fusion Pharmaceuticals Inc. | 2024-02-29 | Added / first present |
| Taysha Gene Therapies, Inc. | Taysha Gene Therapies, Inc. | 2024-02-29 | Added / first present |
| Olema Pharmaceuticals, Inc. | Olema Pharmaceuticals, Inc. | 2024-02-29 | Added / first present |
| EyePoint Pharmaceuticals, Inc. | EyePoint Pharmaceuticals, Inc. | 2024-02-29 | Added / first present |
| Reneo Pharmaceuticals, Inc. | Reneo Pharmaceuticals, Inc. | 2024-02-29 | Added / first present |
| Janux Therapeutics, Inc. | Janux Therapeutics, Inc. | 2024-02-29 | Added / first present |
| Vera Therapeutics, Inc. | Vera Therapeutics, Inc. | 2024-02-29 | Added / first present |
| Prime Medicine, Inc. | Prime Medicine, Inc. | 2024-02-29 | Added / first present |
| Zymeworks Inc. | Zymeworks Inc. | 2024-02-29 | Added / first present |
| Third Harmonic Bio, Inc. | Third Harmonic Bio, Inc. | 2024-02-29 | Added / first present |
| OmniAb, Inc. | OmniAb, Inc. | 2024-02-29 | Added / first present |
| Disc Medicine, Inc. | Disc Medicine, Inc. | 2024-02-29 | Added / first present |
| Structure Therapeutics Inc. | Structure Therapeutics Inc. | 2024-02-29 | Added / first present |
| Enliven Therapeutics, Inc. | Enliven Therapeutics, Inc. | 2024-02-29 | Added / first present |
| Mineralys Therapeutics, Inc. | Mineralys Therapeutics, Inc. | 2024-02-29 | Added / first present |
| Fortrea Holdings Inc. | Fortrea Holdings Inc. | 2024-02-29 | Added / first present |
| Apogee Therapeutics, Inc. | Apogee Therapeutics, Inc. | 2024-02-29 | Added / first present |
| ACELYRIN, Inc. | ACELYRIN, Inc. | 2024-02-29 | Added / first present |
| Tourmaline Bio, Inc. | Tourmaline Bio, Inc. | 2024-02-29 | Added / first present |
| Cartesian Therapeutics, Inc. | Cartesian Therapeutics, Inc. | 2024-02-29 | Added / first present |
| Ambrx Biopharma Inc. | Ambrx Biopharma Inc. | 2024-02-29 | Added / first present |
| Amphastar Pharmaceuticals, Inc. | Amphastar Pharmaceuticals, Inc. | 2023-11-30 | Added / first present |
| Mural Oncology PLC | Mural Oncology PLC | 2023-11-30 | Added / first present |
| Evelo Biosciences, Inc. | Evelo Biosciences, Inc. | 2023-08-31 | Added / first present |
| ANI Pharmaceuticals, Inc. | ANI Pharmaceuticals, Inc. | 2023-02-28 | Added / first present |
| Ardelyx, Inc. | Ardelyx, Inc. | 2023-02-28 | Added / first present |
| Verona Pharma PLC | Verona Pharma PLC | 2023-02-28 | Added / first present |
| Concert Pharmaceuticals, Inc. | Concert Pharmaceuticals, Inc. | 2023-02-28 | Added / first present |
| Tarsus Pharmaceuticals, Inc. | Tarsus Pharmaceuticals, Inc. | 2023-02-28 | Added / first present |
| Foghorn Therapeutics Inc. | Foghorn Therapeutics Inc. | 2023-02-28 | Added / first present |
| Immunocore Holdings PLC | Immunocore Holdings PLC | 2023-02-28 | Added / first present |
| Tango Therapeutics, Inc. | Tango Therapeutics, Inc. | 2023-02-28 | Added / first present |
| Invivyd, Inc. | Invivyd, Inc. | 2023-02-28 | Added / first present |
| Cue Health Inc. | Cue Health Inc. | 2023-02-28 | Added / first present |
| 2Seventy Bio, Inc. | 2Seventy Bio, Inc. | 2023-02-28 | Added / first present |
| DICE Therapeutics, Inc. | DICE Therapeutics, Inc. | 2023-02-28 | Added / first present |
| Ventyx Biosciences, Inc. | Ventyx Biosciences, Inc. | 2023-02-28 | Added / first present |
| Roivant Sciences Ltd. | Roivant Sciences Ltd. | 2023-02-28 | Added / first present |
| Exscientia PLC | Exscientia PLC | 2023-02-28 | Added / first present |
| Arcellx, Inc. | Arcellx, Inc. | 2023-02-28 | Added / first present |
| EQRx, Inc. | EQRx, Inc. | 2023-02-28 | Added / first present |
| GreenLight Biosciences Holdings, PBC | GreenLight Biosciences Holdings, PBC | 2023-02-28 | Added / first present |
| Amylyx Pharmaceuticals, Inc. | Amylyx Pharmaceuticals, Inc. | 2023-02-28 | Added / first present |
| HilleVax, Inc. | HilleVax, Inc. | 2023-02-28 | Added / first present |
| PepGen Inc. | PepGen Inc. | 2023-02-28 | Added / first present |
| Syros Pharmaceuticals, Inc. | Syros Pharmaceuticals, Inc. | 2022-11-30 | Added / first present |
| Eterna Therapeutics Inc. | Eterna Therapeutics Inc. | 2022-11-30 | Added / first present |
| OmniAb, Inc. | OmniAb, Inc. | 2022-11-30 | Added / first present |
| Solid Biosciences Inc. | Solid Biosciences Inc. | 2022-11-30 | Added / first present |
| OmniAb, Inc. | OmniAb, Inc. | 2022-11-30 | Added / first present |
| OmniAb, Inc. | OmniAb, Inc. | 2022-11-30 | Added / first present |
| TherapeuticsMD, Inc. | TherapeuticsMD, Inc. | 2022-05-31 | Added / first present |
| Tonix Pharmaceuticals Holding Corp. | Tonix Pharmaceuticals Holding Corp. | 2022-05-31 | Added / first present |
| Evolus, Inc. | Evolus, Inc. | 2022-02-28 | Added / first present |
| Solid Biosciences, Inc. | Solid Biosciences, Inc. | 2022-02-28 | Added / first present |
| Lexicon Pharmaceuticals, Inc. | Lexicon Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Aclaris Therapeutics, Inc. | Aclaris Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Optinose, Inc. | Optinose, Inc. | 2022-02-28 | Added / first present |
| Molecular Templates, Inc. | Molecular Templates, Inc. | 2022-02-28 | Added / first present |
| Clearside Biomedical, Inc. | Clearside Biomedical, Inc. | 2022-02-28 | Added / first present |
| Aquestive Therapeutics, Inc. | Aquestive Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Morphic Holding, Inc. | Morphic Holding, Inc. | 2022-02-28 | Added / first present |
| Verrica Pharmaceuticals, Inc. | Verrica Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Gritstone bio, Inc. | Gritstone bio, Inc. | 2022-02-28 | Added / first present |
| Evelo Biosciences, Inc. | Evelo Biosciences, Inc. | 2022-02-28 | Added / first present |
| Harrow Health, Inc. | Harrow Health, Inc. | 2022-02-28 | Added / first present |
| Harvard Bioscience, Inc. | Harvard Bioscience, Inc. | 2022-02-28 | Added / first present |
| Mustang Bio, Inc. | Mustang Bio, Inc. | 2022-02-28 | Added / first present |
| Chimerix, Inc. | Chimerix, Inc. | 2022-02-28 | Added / first present |
| Anavex Life Sciences Corp. | Anavex Life Sciences Corp. | 2022-02-28 | Added / first present |
| ADMA Biologics, Inc. | ADMA Biologics, Inc. | 2022-02-28 | Added / first present |
| Sesen Bio, Inc. | Sesen Bio, Inc. | 2022-02-28 | Added / first present |
| Infinity Pharmaceuticals, Inc. | Infinity Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Curis, Inc. | Curis, Inc. | 2022-02-28 | Added / first present |
| Alpine Immune Sciences, Inc. | Alpine Immune Sciences, Inc. | 2022-02-28 | Added / first present |
| Corvus Pharmaceuticals, Inc. | Corvus Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Oncocyte Corp. | Oncocyte Corp. | 2022-02-28 | Added / first present |
| Mirum Pharmaceuticals, Inc. | Mirum Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Leap Therapeutics, Inc. | Leap Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Novocure Ltd. | Novocure Ltd. | 2022-02-28 | Added / first present |
| ProQR Therapeutics N.V. | ProQR Therapeutics N.V. | 2022-02-28 | Added / first present |
| Phathom Pharmaceuticals, Inc. | Phathom Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| 89bio, Inc. | 89bio, Inc. | 2022-02-28 | Added / first present |
| Oyster Point Pharma, Inc. | Oyster Point Pharma, Inc. | 2022-02-28 | Added / first present |
| Tonix Pharmaceuticals Holding Corp. | Tonix Pharmaceuticals Holding Corp. | 2022-02-28 | Added / first present |
| Merus N.V. | Merus N.V. | 2022-02-28 | Added / first present |
| Taysha Gene Therapies, Inc. | Taysha Gene Therapies, Inc. | 2022-02-28 | Added / first present |
| PMV Pharmaceuticals, Inc. | PMV Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Kymera Therapeutics, Inc. | Kymera Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Dyne Therapeutics, Inc. | Dyne Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Harmony Biosciences Holdings, Inc. | Harmony Biosciences Holdings, Inc. | 2022-02-28 | Added / first present |
| Kronos Bio, Inc. | Kronos Bio, Inc. | 2022-02-28 | Added / first present |
| Prelude Therapeutics, Inc. | Prelude Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Shattuck Labs, Inc. | Shattuck Labs, Inc. | 2022-02-28 | Added / first present |
| Inhibrx, Inc. | Inhibrx, Inc. | 2022-02-28 | Added / first present |
| BELLUS Health, Inc. | BELLUS Health, Inc. | 2022-02-28 | Added / first present |
| Athira Pharma, Inc. | Athira Pharma, Inc. | 2022-02-28 | Added / first present |
| Viatris, Inc. | Viatris, Inc. | 2022-02-28 | Added / first present |
| Praxis Precision Medicines, Inc. | Praxis Precision Medicines, Inc. | 2022-02-28 | Added / first present |
| Olema Pharmaceuticals, Inc. | Olema Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| C4 Therapeutics, Inc. | C4 Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Kinnate Biopharma, Inc. | Kinnate Biopharma, Inc. | 2022-02-28 | Added / first present |
| BioAtla, Inc. | BioAtla, Inc. | 2022-02-28 | Added / first present |
| Atea Pharmaceuticals, Inc. | Atea Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Silverback Therapeutics, Inc. | Silverback Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Maravai LifeSciences Holdings, Inc. | Maravai LifeSciences Holdings, Inc. | 2022-02-28 | Added / first present |
| 4D Molecular Therapeutics, Inc. | 4D Molecular Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Seer, Inc. | Seer, Inc. | 2022-02-28 | Added / first present |
| Cullinan Oncology, Inc. | Cullinan Oncology, Inc. | 2022-02-28 | Added / first present |
| Gracell Biotechnologies, Inc. | Gracell Biotechnologies, Inc. | 2022-02-28 | Added / first present |
| AbCellera Biologics, Inc. | AbCellera Biologics, Inc. | 2022-02-28 | Added / first present |
| Cogent Biosciences, Inc. | Cogent Biosciences, Inc. | 2022-02-28 | Added / first present |
| Aligos Therapeutics, Inc. | Aligos Therapeutics, Inc. | 2022-02-28 | Added / first present |
| EyePoint Pharmaceuticals, Inc. | EyePoint Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Oncorus, Inc. | Oncorus, Inc. | 2022-02-28 | Added / first present |
| Codiak Biosciences, Inc. | Codiak Biosciences, Inc. | 2022-02-28 | Added / first present |
| Design Therapeutics, Inc. | Design Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Decibel Therapeutics, Inc. | Decibel Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Connect Biopharma Holdings Ltd. | Connect Biopharma Holdings Ltd. | 2022-02-28 | Added / first present |
| Prometheus Biosciences, Inc. | Prometheus Biosciences, Inc. | 2022-02-28 | Added / first present |
| Recursion Pharmaceuticals, Inc. | Recursion Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Instil Bio, Inc. | Instil Bio, Inc. | 2022-02-28 | Added / first present |
| Vor BioPharma, Inc. | Vor BioPharma, Inc. | 2022-02-28 | Added / first present |
| Sana Biotechnology, Inc. | Sana Biotechnology, Inc. | 2022-02-28 | Added / first present |
| Bolt Biotherapeutics, Inc. | Bolt Biotherapeutics, Inc. | 2022-02-28 | Added / first present |
| Mereo Biopharma Group PLC | Mereo Biopharma Group PLC | 2022-02-28 | Added / first present |
| Viracta Therapeutics, Inc. | Viracta Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Brooklyn ImmunoTherapeutics, Inc. | Brooklyn ImmunoTherapeutics, Inc. | 2022-02-28 | Added / first present |
| Terns Pharmaceuticals, Inc. | Terns Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Sensei Biotherapeutics, Inc. | Sensei Biotherapeutics, Inc. | 2022-02-28 | Added / first present |
| Landos Biopharma, Inc. | Landos Biopharma, Inc. | 2022-02-28 | Added / first present |
| Bioventus, Inc. | Bioventus, Inc. | 2022-02-28 | Added / first present |
| KemPharm, Inc. | KemPharm, Inc. | 2022-02-28 | Added / first present |
| Edgewise Therapeutics, Inc. | Edgewise Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Ikena Oncology, Inc. | Ikena Oncology, Inc. | 2022-02-28 | Added / first present |
| CureVac N.V. | CureVac N.V. | 2022-02-28 | Added / first present |
| Monte Rosa Therapeutics, Inc. | Monte Rosa Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Talaris Therapeutics, Inc. | Talaris Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Nautilus Biotechnology, Inc. | Nautilus Biotechnology, Inc. | 2022-02-28 | Added / first present |
| Biomea Fusion, Inc. | Biomea Fusion, Inc. | 2022-02-28 | Added / first present |
| Verve Therapeutics, Inc. | Verve Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Day One Biopharmaceuticals, Inc. | Day One Biopharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Absci Corp. | Absci Corp. | 2022-02-28 | Added / first present |
| Werewolf Therapeutics, Inc. | Werewolf Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Rain Therapeutics, Inc. | Rain Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Impel Neuropharma, Inc. | Impel Neuropharma, Inc. | 2022-02-28 | Added / first present |
| Lyell Immunopharma, Inc. | Lyell Immunopharma, Inc. | 2022-02-28 | Added / first present |
| Singular Genomics Systems, Inc. | Singular Genomics Systems, Inc. | 2022-02-28 | Added / first present |
| MaxCyte, Inc. | MaxCyte, Inc. | 2022-02-28 | Added / first present |
| Cyteir Therapeutics, Inc. | Cyteir Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Alpha Teknova, Inc. | Alpha Teknova, Inc. | 2022-02-28 | Added / first present |
| Codex DNA, Inc. | Codex DNA, Inc. | 2022-02-28 | Added / first present |
| Graphite Bio, Inc. | Graphite Bio, Inc. | 2022-02-28 | Added / first present |
| Century Therapeutics, Inc. | Century Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Janux Therapeutics, Inc. | Janux Therapeutics, Inc. | 2022-02-28 | Added / first present |
| NRX Pharmaceuticals, Inc. | NRX Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Tenaya Therapeutics, Inc. | Tenaya Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Imago Biosciences, Inc. | Imago Biosciences, Inc. | 2022-02-28 | Added / first present |
| Omega Therapeutics, Inc. | Omega Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Immuneering Corp. | Immuneering Corp. | 2022-02-28 | Added / first present |
| Rapid Micro Biosystems, Inc. | Rapid Micro Biosystems, Inc. | 2022-02-28 | Added / first present |
| Icosavax, Inc. | Icosavax, Inc. | 2022-02-28 | Added / first present |
| Acumen Pharmaceuticals, Inc. | Acumen Pharmaceuticals, Inc. | 2022-02-28 | Added / first present |
| Erasca, Inc. | Erasca, Inc. | 2022-02-28 | Added / first present |
| Nuvalent, Inc. | Nuvalent, Inc. | 2022-02-28 | Added / first present |
| Bicycle Therapeutics PLC | Bicycle Therapeutics PLC | 2022-02-28 | Added / first present |
| Compass Pathways Plc | Compass Pathways Plc | 2022-02-28 | Added / first present |
| Rallybio Corp. | Rallybio Corp. | 2022-02-28 | Added / first present |
| Caribou Biosciences, Inc. | Caribou Biosciences, Inc. | 2022-02-28 | Added / first present |
| 23andMe Holding Co. | 23andMe Holding Co. | 2022-02-28 | Added / first present |
| Quantum-Si, Inc. | Quantum-Si, Inc. | 2022-02-28 | Added / first present |
| Aerovate Therapeutics, Inc. | Aerovate Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Candel Therapeutics, Inc. | Candel Therapeutics, Inc. | 2022-02-28 | Added / first present |
| Sera Prognostics, Inc. | Sera Prognostics, Inc. | 2022-02-28 | Added / first present |
| Rani Therapeutics Holdings, Inc. | Rani Therapeutics Holdings, Inc. | 2022-02-28 | Added / first present |
| Humacyte, Inc. | Humacyte, Inc. | 2022-02-28 | Added / first present |
| ObsEva S.A. | ObsEva S.A. | 2022-02-28 | Added / first present |
| Abcam PLC | Abcam PLC | 2022-02-28 | Added / first present |
| Centessa Pharmaceuticals PLC | Centessa Pharmaceuticals PLC | 2022-02-28 | Added / first present |
| Achilles Therapeutics PLC | Achilles Therapeutics PLC | 2022-02-28 | Added / first present |
| SAB Biotherapeutics, Inc. | SAB Biotherapeutics, Inc. | 2022-02-28 | Added / first present |
| ATAI Life Sciences N.V. | ATAI Life Sciences N.V. | 2022-02-28 | Added / first present |
| Xeris Biopharma Holdings, Inc. | Xeris Biopharma Holdings, Inc. | 2021-11-30 | Added / first present |
| 2seventy bio, Inc. | 2seventy bio, Inc. | 2021-11-30 | Added / first present |
Removals
| Ticker | Issuer | Observed date | Change |
|---|---|---|---|
| Mersana Therapeutics, Inc. | Mersana Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| Amarin Corp. PLC | Amarin Corp. PLC | 2026-02-28 | Removed / first absent |
| Fate Therapeutics, Inc. | Fate Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| Sutro Biopharma, Inc. | Sutro Biopharma, Inc. | 2026-02-28 | Removed / first absent |
| Mersana Therapeutics, Inc. | Mersana Therapeutics, Inc. | 2025-08-31 | Removed / first absent |
| scPharmaceuticals Inc. | scPharmaceuticals Inc. | 2025-11-30 | Removed / first absent |
| Applied Therapeutics, Inc. | Applied Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| IGM Biosciences, Inc. | IGM Biosciences, Inc. | 2025-08-31 | Removed / first absent |
| Nkarta, Inc. | Nkarta, Inc. | 2026-02-28 | Removed / first absent |
| Inozyme Pharma, Inc. | Inozyme Pharma, Inc. | 2025-08-31 | Removed / first absent |
| TScan Therapeutics, Inc. | TScan Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| Astria Therapeutics, Inc. | Astria Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| Climb Bio, Inc. | Climb Bio, Inc. | 2026-02-28 | Removed / first absent |
| 2seventy bio, Inc. | 2seventy bio, Inc. | 2025-05-31 | Removed / first absent |
| Indivior PLC | Indivior PLC | 2026-02-28 | Removed / first absent |
| Mind Medicine (MindMed) Inc. | Mind Medicine (MindMed) Inc. | 2026-02-28 | Removed / first absent |
| Acrivon Therapeutics, Inc. | Acrivon Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| CARGO Therapeutics, Inc. | CARGO Therapeutics, Inc. | 2025-08-31 | Removed / first absent |
| Q32 Bio Inc. | Q32 Bio Inc. | 2026-02-28 | Removed / first absent |
| Cartesian Therapeutics, Inc. | Cartesian Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| Tevogen Bio Holdings Inc. | Tevogen Bio Holdings Inc. | 2026-02-28 | Removed / first absent |
| Artiva Biotherapeutics, Inc. | Artiva Biotherapeutics, Inc. | 2026-02-28 | Removed / first absent |
| Invesco Government & Agency Portfolio | Invesco Government & Agency Portfolio | 2025-05-31 | Removed / first absent |
| 23andMe Holding Co. | 23andMe Holding Co. | 2025-02-28 | Removed / first absent |
| OnKure Therapeutics, Inc. | OnKure Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| Avadel Pharmaceuticals PLC | Avadel Pharmaceuticals PLC | 2026-02-28 | Removed / first absent |
| Dynavax Technologies Corp. | Dynavax Technologies Corp. | 2026-02-28 | Removed / first absent |
| Y-mAbs Therapeutics, Inc. | Y-mAbs Therapeutics, Inc. | 2025-11-30 | Removed / first absent |
| Ovid Therapeutics Inc. | Ovid Therapeutics Inc. | 2025-02-28 | Removed / first absent |
| Cabaletta Bio, Inc. | Cabaletta Bio, Inc. | 2025-02-28 | Removed / first absent |
| Fusion Pharmaceuticals Inc. | Fusion Pharmaceuticals Inc. | 2024-08-31 | Removed / first absent |
| Reneo Pharmaceuticals, Inc. | Reneo Pharmaceuticals, Inc. | 2024-11-30 | Removed / first absent |
| ACELYRIN, Inc. | ACELYRIN, Inc. | 2025-05-31 | Removed / first absent |
| Tourmaline Bio, Inc. | Tourmaline Bio, Inc. | 2025-11-30 | Removed / first absent |
| Ambrx Biopharma Inc. | Ambrx Biopharma Inc. | 2024-05-31 | Removed / first absent |
| Mural Oncology PLC | Mural Oncology PLC | 2024-02-29 | Removed / first absent |
| Evelo Biosciences, Inc. | Evelo Biosciences, Inc. | 2024-02-29 | Removed / first absent |
| Verona Pharma PLC | Verona Pharma PLC | 2025-11-30 | Removed / first absent |
| Concert Pharmaceuticals, Inc. | Concert Pharmaceuticals, Inc. | 2023-05-31 | Removed / first absent |
| Foghorn Therapeutics Inc. | Foghorn Therapeutics Inc. | 2024-02-29 | Removed / first absent |
| Invivyd, Inc. | Invivyd, Inc. | 2024-02-29 | Removed / first absent |
| Cue Health Inc. | Cue Health Inc. | 2024-02-29 | Removed / first absent |
| 2Seventy Bio, Inc. | 2Seventy Bio, Inc. | 2024-02-29 | Removed / first absent |
| DICE Therapeutics, Inc. | DICE Therapeutics, Inc. | 2023-08-31 | Removed / first absent |
| Ventyx Biosciences, Inc. | Ventyx Biosciences, Inc. | 2025-02-28 | Removed / first absent |
| Exscientia PLC | Exscientia PLC | 2024-11-30 | Removed / first absent |
| EQRx, Inc. | EQRx, Inc. | 2023-11-30 | Removed / first absent |
| GreenLight Biosciences Holdings, PBC | GreenLight Biosciences Holdings, PBC | 2023-08-31 | Removed / first absent |
| HilleVax, Inc. | HilleVax, Inc. | 2024-02-29 | Removed / first absent |
| PepGen Inc. | PepGen Inc. | 2024-02-29 | Removed / first absent |
| Syros Pharmaceuticals, Inc. | Syros Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Eterna Therapeutics Inc. | Eterna Therapeutics Inc. | 2023-02-28 | Removed / first absent |
| OmniAb, Inc. | OmniAb, Inc. | 2023-02-28 | Removed / first absent |
| Solid Biosciences Inc. | Solid Biosciences Inc. | 2023-02-28 | Removed / first absent |
| TherapeuticsMD, Inc. | TherapeuticsMD, Inc. | 2022-08-31 | Removed / first absent |
| Tonix Pharmaceuticals Holding Corp. | Tonix Pharmaceuticals Holding Corp. | 2023-02-28 | Removed / first absent |
| Solid Biosciences, Inc. | Solid Biosciences, Inc. | 2022-11-30 | Removed / first absent |
| Lexicon Pharmaceuticals, Inc. | Lexicon Pharmaceuticals, Inc. | 2026-02-28 | Removed / first absent |
| Aclaris Therapeutics, Inc. | Aclaris Therapeutics, Inc. | 2025-02-28 | Removed / first absent |
| Optinose, Inc. | Optinose, Inc. | 2024-02-29 | Removed / first absent |
| Molecular Templates, Inc. | Molecular Templates, Inc. | 2023-02-28 | Removed / first absent |
| Clearside Biomedical, Inc. | Clearside Biomedical, Inc. | 2023-02-28 | Removed / first absent |
| Aquestive Therapeutics, Inc. | Aquestive Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Morphic Holding, Inc. | Morphic Holding, Inc. | 2024-08-31 | Removed / first absent |
| Verrica Pharmaceuticals, Inc. | Verrica Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Gritstone bio, Inc. | Gritstone bio, Inc. | 2024-02-29 | Removed / first absent |
| Evelo Biosciences, Inc. | Evelo Biosciences, Inc. | 2023-08-31 | Removed / first absent |
| Harvard Bioscience, Inc. | Harvard Bioscience, Inc. | 2023-02-28 | Removed / first absent |
| Mustang Bio, Inc. | Mustang Bio, Inc. | 2023-02-28 | Removed / first absent |
| Chimerix, Inc. | Chimerix, Inc. | 2023-02-28 | Removed / first absent |
| Sesen Bio, Inc. | Sesen Bio, Inc. | 2023-02-28 | Removed / first absent |
| Infinity Pharmaceuticals, Inc. | Infinity Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Curis, Inc. | Curis, Inc. | 2023-02-28 | Removed / first absent |
| Alpine Immune Sciences, Inc. | Alpine Immune Sciences, Inc. | 2024-05-31 | Removed / first absent |
| Corvus Pharmaceuticals, Inc. | Corvus Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Oncocyte Corp. | Oncocyte Corp. | 2023-02-28 | Removed / first absent |
| Leap Therapeutics, Inc. | Leap Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| ProQR Therapeutics N.V. | ProQR Therapeutics N.V. | 2023-02-28 | Removed / first absent |
| 89bio, Inc. | 89bio, Inc. | 2025-11-30 | Removed / first absent |
| Oyster Point Pharma, Inc. | Oyster Point Pharma, Inc. | 2023-02-28 | Removed / first absent |
| Tonix Pharmaceuticals Holding Corp. | Tonix Pharmaceuticals Holding Corp. | 2022-05-31 | Removed / first absent |
| Merus N.V. | Merus N.V. | 2026-02-28 | Removed / first absent |
| Taysha Gene Therapies, Inc. | Taysha Gene Therapies, Inc. | 2023-02-28 | Removed / first absent |
| PMV Pharmaceuticals, Inc. | PMV Pharmaceuticals, Inc. | 2024-02-29 | Removed / first absent |
| Kronos Bio, Inc. | Kronos Bio, Inc. | 2023-02-28 | Removed / first absent |
| Prelude Therapeutics, Inc. | Prelude Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Shattuck Labs, Inc. | Shattuck Labs, Inc. | 2023-02-28 | Removed / first absent |
| Inhibrx, Inc. | Inhibrx, Inc. | 2024-05-31 | Removed / first absent |
| BELLUS Health, Inc. | BELLUS Health, Inc. | 2023-08-31 | Removed / first absent |
| Athira Pharma, Inc. | Athira Pharma, Inc. | 2023-02-28 | Removed / first absent |
| Praxis Precision Medicines, Inc. | Praxis Precision Medicines, Inc. | 2023-02-28 | Removed / first absent |
| Olema Pharmaceuticals, Inc. | Olema Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| C4 Therapeutics, Inc. | C4 Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Kinnate Biopharma, Inc. | Kinnate Biopharma, Inc. | 2024-02-29 | Removed / first absent |
| BioAtla, Inc. | BioAtla, Inc. | 2024-02-29 | Removed / first absent |
| Seer, Inc. | Seer, Inc. | 2023-02-28 | Removed / first absent |
| Gracell Biotechnologies, Inc. | Gracell Biotechnologies, Inc. | 2024-02-29 | Removed / first absent |
| Aligos Therapeutics, Inc. | Aligos Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| EyePoint Pharmaceuticals, Inc. | EyePoint Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Oncorus, Inc. | Oncorus, Inc. | 2023-02-28 | Removed / first absent |
| Codiak Biosciences, Inc. | Codiak Biosciences, Inc. | 2023-02-28 | Removed / first absent |
| Design Therapeutics, Inc. | Design Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Decibel Therapeutics, Inc. | Decibel Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Connect Biopharma Holdings Ltd. | Connect Biopharma Holdings Ltd. | 2023-02-28 | Removed / first absent |
| Prometheus Biosciences, Inc. | Prometheus Biosciences, Inc. | 2023-08-31 | Removed / first absent |
| Instil Bio, Inc. | Instil Bio, Inc. | 2024-02-29 | Removed / first absent |
| Vor BioPharma, Inc. | Vor BioPharma, Inc. | 2023-02-28 | Removed / first absent |
| Bolt Biotherapeutics, Inc. | Bolt Biotherapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Mereo Biopharma Group PLC | Mereo Biopharma Group PLC | 2023-02-28 | Removed / first absent |
| Viracta Therapeutics, Inc. | Viracta Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Brooklyn ImmunoTherapeutics, Inc. | Brooklyn ImmunoTherapeutics, Inc. | 2022-11-30 | Removed / first absent |
| Sensei Biotherapeutics, Inc. | Sensei Biotherapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Landos Biopharma, Inc. | Landos Biopharma, Inc. | 2023-02-28 | Removed / first absent |
| Bioventus, Inc. | Bioventus, Inc. | 2023-02-28 | Removed / first absent |
| KemPharm, Inc. | KemPharm, Inc. | 2023-02-28 | Removed / first absent |
| Ikena Oncology, Inc. | Ikena Oncology, Inc. | 2023-02-28 | Removed / first absent |
| CureVac N.V. | CureVac N.V. | 2026-02-28 | Removed / first absent |
| Monte Rosa Therapeutics, Inc. | Monte Rosa Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Talaris Therapeutics, Inc. | Talaris Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Nautilus Biotechnology, Inc. | Nautilus Biotechnology, Inc. | 2025-02-28 | Removed / first absent |
| Biomea Fusion, Inc. | Biomea Fusion, Inc. | 2026-02-28 | Removed / first absent |
| Verve Therapeutics, Inc. | Verve Therapeutics, Inc. | 2025-08-31 | Removed / first absent |
| Absci Corp. | Absci Corp. | 2024-02-29 | Removed / first absent |
| Werewolf Therapeutics, Inc. | Werewolf Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Rain Therapeutics, Inc. | Rain Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Impel Neuropharma, Inc. | Impel Neuropharma, Inc. | 2023-02-28 | Removed / first absent |
| Lyell Immunopharma, Inc. | Lyell Immunopharma, Inc. | 2025-08-31 | Removed / first absent |
| Singular Genomics Systems, Inc. | Singular Genomics Systems, Inc. | 2023-02-28 | Removed / first absent |
| MaxCyte, Inc. | MaxCyte, Inc. | 2026-02-28 | Removed / first absent |
| Cyteir Therapeutics, Inc. | Cyteir Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Alpha Teknova, Inc. | Alpha Teknova, Inc. | 2023-02-28 | Removed / first absent |
| Codex DNA, Inc. | Codex DNA, Inc. | 2023-02-28 | Removed / first absent |
| Graphite Bio, Inc. | Graphite Bio, Inc. | 2024-02-29 | Removed / first absent |
| Century Therapeutics, Inc. | Century Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Janux Therapeutics, Inc. | Janux Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| NRX Pharmaceuticals, Inc. | NRX Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Tenaya Therapeutics, Inc. | Tenaya Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Imago Biosciences, Inc. | Imago Biosciences, Inc. | 2023-02-28 | Removed / first absent |
| Omega Therapeutics, Inc. | Omega Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Immuneering Corp. | Immuneering Corp. | 2024-02-29 | Removed / first absent |
| Rapid Micro Biosystems, Inc. | Rapid Micro Biosystems, Inc. | 2023-02-28 | Removed / first absent |
| Icosavax, Inc. | Icosavax, Inc. | 2023-02-28 | Removed / first absent |
| Acumen Pharmaceuticals, Inc. | Acumen Pharmaceuticals, Inc. | 2024-02-29 | Removed / first absent |
| Compass Pathways Plc | Compass Pathways Plc | 2024-02-29 | Removed / first absent |
| Rallybio Corp. | Rallybio Corp. | 2023-02-28 | Removed / first absent |
| Caribou Biosciences, Inc. | Caribou Biosciences, Inc. | 2025-02-28 | Removed / first absent |
| 23andMe Holding Co. | 23andMe Holding Co. | 2024-11-30 | Removed / first absent |
| Quantum-Si, Inc. | Quantum-Si, Inc. | 2024-02-29 | Removed / first absent |
| Aerovate Therapeutics, Inc. | Aerovate Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Candel Therapeutics, Inc. | Candel Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Sera Prognostics, Inc. | Sera Prognostics, Inc. | 2023-02-28 | Removed / first absent |
| Rani Therapeutics Holdings, Inc. | Rani Therapeutics Holdings, Inc. | 2023-02-28 | Removed / first absent |
| ObsEva S.A. | ObsEva S.A. | 2023-02-28 | Removed / first absent |
| Abcam PLC | Abcam PLC | 2024-02-29 | Removed / first absent |
| Achilles Therapeutics PLC | Achilles Therapeutics PLC | 2023-02-28 | Removed / first absent |
| SAB Biotherapeutics, Inc. | SAB Biotherapeutics, Inc. | 2023-02-28 | Removed / first absent |
| ATAI Life Sciences N.V. | ATAI Life Sciences N.V. | 2025-02-28 | Removed / first absent |
| 2seventy bio, Inc. | 2seventy bio, Inc. | 2022-02-28 | Removed / first absent |
| Hutchison China MediTech Ltd. | Hutchison China MediTech Ltd. | 2026-02-28 | Removed / first absent |
| Nektar Therapeutics | Nektar Therapeutics | 2024-02-29 | Removed / first absent |
| Sage Therapeutics, Inc. | Sage Therapeutics, Inc. | 2025-08-31 | Removed / first absent |
| Bluebird Bio, Inc. | Bluebird Bio, Inc. | 2025-02-28 | Removed / first absent |
| PetIQ, Inc. | PetIQ, Inc. | 2024-11-30 | Removed / first absent |
| Puma Biotechnology, Inc. | Puma Biotechnology, Inc. | 2023-02-28 | Removed / first absent |
| Aerie Pharmaceuticals, Inc. | Aerie Pharmaceuticals, Inc. | 2022-11-30 | Removed / first absent |
| AstraZeneca PLC | AstraZeneca PLC | 2026-02-28 | Removed / first absent |
| Allakos, Inc. | Allakos, Inc. | 2024-02-29 | Removed / first absent |
| Acceleron Pharma, Inc. | Acceleron Pharma, Inc. | 2021-11-30 | Removed / first absent |
| Arena Pharmaceuticals, Inc. | Arena Pharmaceuticals, Inc. | 2022-05-31 | Removed / first absent |
| Mirati Therapeutics, Inc. | Mirati Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Blueprint Medicines Corp. | Blueprint Medicines Corp. | 2025-08-31 | Removed / first absent |
| Reata Pharmaceuticals, Inc. | Reata Pharmaceuticals, Inc. | 2023-11-30 | Removed / first absent |
| Tricida, Inc. | Tricida, Inc. | 2023-02-28 | Removed / first absent |
| Atreca, Inc. | Atreca, Inc. | 2022-02-28 | Removed / first absent |
| Syneos Health, Inc. | Syneos Health, Inc. | 2023-11-30 | Removed / first absent |
| FibroGen, Inc. | FibroGen, Inc. | 2024-02-29 | Removed / first absent |
| Global Blood Therapeutics, Inc. | Global Blood Therapeutics, Inc. | 2022-11-30 | Removed / first absent |
| Intercept Pharmaceuticals, Inc. | Intercept Pharmaceuticals, Inc. | 2023-11-30 | Removed / first absent |
| Zogenix, Inc. | Zogenix, Inc. | 2022-05-31 | Removed / first absent |
| Coherus Biosciences, Inc. | Coherus Biosciences, Inc. | 2025-02-28 | Removed / first absent |
| Deciphera Pharmaceuticals, Inc. | Deciphera Pharmaceuticals, Inc. | 2024-08-31 | Removed / first absent |
| Radius Health, Inc. | Radius Health, Inc. | 2022-08-31 | Removed / first absent |
| Fate Therapeutics, Inc. | Fate Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Esperion Therapeutics, Inc. | Esperion Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Sangamo Therapeutics, Inc. | Sangamo Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Spectrum Pharmaceuticals, Inc. | Spectrum Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Dicerna Pharmaceuticals, Inc. | Dicerna Pharmaceuticals, Inc. | 2022-02-28 | Removed / first absent |
| G1 Therapeutics, Inc. | G1 Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| TherapeuticsMD, Inc. | TherapeuticsMD, Inc. | 2022-05-31 | Removed / first absent |
| Athenex, Inc. | Athenex, Inc. | 2023-02-28 | Removed / first absent |
| Epizyme, Inc. | Epizyme, Inc. | 2022-08-31 | Removed / first absent |
| Omeros Corp. | Omeros Corp. | 2024-02-29 | Removed / first absent |
| Cara Therapeutics, Inc. | Cara Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| NanoString Technologies, Inc. | NanoString Technologies, Inc. | 2024-02-29 | Removed / first absent |
| Atara Biotherapeutics, Inc. | Atara Biotherapeutics, Inc. | 2024-02-29 | Removed / first absent |
| MacroGenics, Inc. | MacroGenics, Inc. | 2026-02-28 | Removed / first absent |
| Rubius Therapeutics, Inc. | Rubius Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Karyopharm Therapeutics, Inc. | Karyopharm Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Revance Therapeutics, Inc. | Revance Therapeutics, Inc. | 2025-02-28 | Removed / first absent |
| ZIOPHARM Oncology, Inc. | ZIOPHARM Oncology, Inc. | 2024-02-29 | Removed / first absent |
| Voyager Therapeutics, Inc. | Voyager Therapeutics, Inc. | 2022-02-28 | Removed / first absent |
| Flexion Therapeutics, Inc. | Flexion Therapeutics, Inc. | 2021-11-30 | Removed / first absent |
| Akebia Therapeutics, Inc. | Akebia Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Intra-Cellular Therapies, Inc. | Intra-Cellular Therapies, Inc. | 2025-05-31 | Removed / first absent |
| ImmunoGen, Inc. | ImmunoGen, Inc. | 2024-02-29 | Removed / first absent |
| ChemoCentryx, Inc. | ChemoCentryx, Inc. | 2022-11-30 | Removed / first absent |
| Avrobio, Inc. | Avrobio, Inc. | 2023-02-28 | Removed / first absent |
| CytomX Therapeutics, Inc. | CytomX Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Rigel Pharmaceuticals, Inc. | Rigel Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Cymabay Therapeutics, Inc. | Cymabay Therapeutics, Inc. | 2024-05-31 | Removed / first absent |
| Clovis Oncology, Inc. | Clovis Oncology, Inc. | 2023-02-28 | Removed / first absent |
| Assembly Biosciences, Inc. | Assembly Biosciences, Inc. | 2022-02-28 | Removed / first absent |
| Inovio Pharmaceuticals, Inc. | Inovio Pharmaceuticals, Inc. | 2024-02-29 | Removed / first absent |
| Verastem, Inc. | Verastem, Inc. | 2023-02-28 | Removed / first absent |
| ANI Pharmaceuticals, Inc. | ANI Pharmaceuticals, Inc. | 2022-02-28 | Removed / first absent |
| Amphastar Pharmaceuticals, Inc. | Amphastar Pharmaceuticals, Inc. | 2023-08-31 | Removed / first absent |
| Eagle Pharmaceuticals, Inc. | Eagle Pharmaceuticals, Inc. | 2024-02-29 | Removed / first absent |
| Enanta Pharmaceuticals, Inc. | Enanta Pharmaceuticals, Inc. | 2024-02-29 | Removed / first absent |
| Myriad Genetics, Inc. | Myriad Genetics, Inc. | 2025-02-28 | Removed / first absent |
| NextCure, Inc. | NextCure, Inc. | 2023-02-28 | Removed / first absent |
| Surface Oncology, Inc. | Surface Oncology, Inc. | 2023-02-28 | Removed / first absent |
| Endo International PLC | Endo International PLC | 2022-08-31 | Removed / first absent |
| Codexis, Inc. | Codexis, Inc. | 2024-02-29 | Removed / first absent |
| Odonate Therapeutics, Inc. | Odonate Therapeutics, Inc. | 2022-02-28 | Removed / first absent |
| Gossamer Bio. Inc. | Gossamer Bio. Inc. | 2024-02-29 | Removed / first absent |
| Homology Medicines, Inc. | Homology Medicines, Inc. | 2023-02-28 | Removed / first absent |
| Y-mAbs Therapeutics, Inc. | Y-mAbs Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| KalVista Pharmaceuticals, Inc. | KalVista Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| BioDelivery Sciences International, Inc. | BioDelivery Sciences International, Inc. | 2022-05-31 | Removed / first absent |
| Orchard Therapeutics plc | Orchard Therapeutics plc | 2022-02-28 | Removed / first absent |
| Autolus Therapeutics PLC | Autolus Therapeutics PLC | 2023-02-28 | Removed / first absent |
| Redhill Biopharma Ltd. | Redhill Biopharma Ltd. | 2023-02-28 | Removed / first absent |
| Sutro Biopharma, Inc. | Sutro Biopharma, Inc. | 2024-02-29 | Removed / first absent |
| Amarin Corp. PLC | Amarin Corp. PLC | 2025-05-31 | Removed / first absent |
| Ovid therapeutics, Inc. | Ovid therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Avadel Pharmaceuticals PLC | Avadel Pharmaceuticals PLC | 2024-05-31 | Removed / first absent |
| Ardelyx, Inc. | Ardelyx, Inc. | 2022-02-28 | Removed / first absent |
| Cellectis S.A. | Cellectis S.A. | 2023-02-28 | Removed / first absent |
| Magenta Therapeutics, Inc. | Magenta Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Adaptimmune Therapeutics PLC | Adaptimmune Therapeutics PLC | 2024-02-29 | Removed / first absent |
| Translate Bio, Inc. | Translate Bio, Inc. | 2021-11-30 | Removed / first absent |
| Syros Pharmaceuticals, Inc. | Syros Pharmaceuticals, Inc. | 2022-11-30 | Removed / first absent |
| Adverum Biotechnologies, Inc. | Adverum Biotechnologies, Inc. | 2023-02-28 | Removed / first absent |
| MediciNova, Inc. | MediciNova, Inc. | 2022-02-28 | Removed / first absent |
| Seres Therapeutics, Inc. | Seres Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| UNITY Biotechnology, Inc. | UNITY Biotechnology, Inc. | 2022-02-28 | Removed / first absent |
| Xeris Pharmaceuticals, Inc. | Xeris Pharmaceuticals, Inc. | 2021-11-30 | Removed / first absent |
| Eiger BioPharmaceuticals, Inc. | Eiger BioPharmaceuticals, Inc. | 2024-02-29 | Removed / first absent |
| Aeglea BioTherapeutics, Inc. | Aeglea BioTherapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Paratek Pharmaceuticals, Inc. | Paratek Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Concert Pharmaceuticals, Inc. | Concert Pharmaceuticals, Inc. | 2022-02-28 | Removed / first absent |
| Kala Pharmaceuticals, Inc. | Kala Pharmaceuticals, Inc. | 2022-02-28 | Removed / first absent |
| Alector, Inc. | Alector, Inc. | 2026-02-28 | Removed / first absent |
| Jounce Therapeutics, Inc. | Jounce Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Akero Therapeutics, Inc. | Akero Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| Karuna Therapeutics, Inc. | Karuna Therapeutics, Inc. | 2024-05-31 | Removed / first absent |
| Personalis, Inc. | Personalis, Inc. | 2023-02-28 | Removed / first absent |
| Stoke Therapeutics, Inc. | Stoke Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| TCR2 Therapeutics, Inc. | TCR2 Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| NGM Biopharmaceuticals, Inc. | NGM Biopharmaceuticals, Inc. | 2024-02-29 | Removed / first absent |
| Kadmon Holdings, Inc. | Kadmon Holdings, Inc. | 2021-11-30 | Removed / first absent |
| Spero Therapeutics, Inc. | Spero Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Selecta Biosciences, Inc. | Selecta Biosciences, Inc. | 2024-02-29 | Removed / first absent |
| Turning Point Therapeutics, Inc. | Turning Point Therapeutics, Inc. | 2022-08-31 | Removed / first absent |
| Mersana Therapeutics, Inc. | Mersana Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| XBiotech, Inc. | XBiotech, Inc. | 2022-02-28 | Removed / first absent |
| Kezar Life Sciences, Inc. | Kezar Life Sciences, Inc. | 2024-02-29 | Removed / first absent |
| Calithera Biosciences, Inc. | Calithera Biosciences, Inc. | 2022-02-28 | Removed / first absent |
| Provention Bio, Inc. | Provention Bio, Inc. | 2023-05-31 | Removed / first absent |
| Kodiak Sciences, Inc. | Kodiak Sciences, Inc. | 2024-02-29 | Removed / first absent |
| IVERIC bio, Inc. | IVERIC bio, Inc. | 2023-08-31 | Removed / first absent |
| Neoleukin Therapeutics, Inc. | Neoleukin Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Cortexyme, Inc. | Cortexyme, Inc. | 2023-02-28 | Removed / first absent |
| Immunic, Inc. | Immunic, Inc. | 2023-02-28 | Removed / first absent |
| Altimmune, Inc. | Altimmune, Inc. | 2024-02-29 | Removed / first absent |
| Harpoon Therapeutics, Inc. | Harpoon Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Precision BioSciences, Inc. | Precision BioSciences, Inc. | 2023-02-28 | Removed / first absent |
| Kaleido Biosciences, Inc. | Kaleido Biosciences, Inc. | 2022-02-28 | Removed / first absent |
| Fulcrum Therapeutics, Inc. | Fulcrum Therapeutics, Inc. | 2025-02-28 | Removed / first absent |
| Applied Therapeutics, Inc. | Applied Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Horizon Therapeutics PLC | Horizon Therapeutics PLC | 2023-11-30 | Removed / first absent |
| Kiniksa Pharmaceuticals Ltd. | Kiniksa Pharmaceuticals Ltd. | 2024-08-31 | Removed / first absent |
| SpringWorks Therapeutics, Inc. | SpringWorks Therapeutics, Inc. | 2025-08-31 | Removed / first absent |
| IGM Biosciences, Inc. | IGM Biosciences, Inc. | 2024-02-29 | Removed / first absent |
| Frequency Therapeutics, Inc. | Frequency Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Relmada Therapeutics, Inc. | Relmada Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Aprea Therapeutics, Inc. | Aprea Therapeutics, Inc. | 2022-02-28 | Removed / first absent |
| Cabaletta Bio, Inc. | Cabaletta Bio, Inc. | 2023-02-28 | Removed / first absent |
| RAPT Therapeutics, Inc. | RAPT Therapeutics, Inc. | 2025-02-28 | Removed / first absent |
| Affimed N.V. | Affimed N.V. | 2024-02-29 | Removed / first absent |
| AC Immune SA | AC Immune SA | 2023-02-28 | Removed / first absent |
| Passage Bio, Inc. | Passage Bio, Inc. | 2023-02-28 | Removed / first absent |
| Black Diamond Therapeutics, Inc. | Black Diamond Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Osmotica Pharmaceuticals PLC | Osmotica Pharmaceuticals PLC | 2022-02-28 | Removed / first absent |
| Forma Therapeutics Holdings, Inc. | Forma Therapeutics Holdings, Inc. | 2022-11-30 | Removed / first absent |
| Avidity Biosciences, Inc. | Avidity Biosciences, Inc. | 2026-02-28 | Removed / first absent |
| Zentalis Pharmaceuticals, Inc. | Zentalis Pharmaceuticals, Inc. | 2025-02-28 | Removed / first absent |
| Akouos, Inc. | Akouos, Inc. | 2022-11-30 | Removed / first absent |
| ORIC Pharmaceuticals, Inc. | ORIC Pharmaceuticals, Inc. | 2023-02-28 | Removed / first absent |
| Fusion Pharmaceuticals, Inc. | Fusion Pharmaceuticals, Inc. | 2022-02-28 | Removed / first absent |
| Applied Molecular Transport, Inc. | Applied Molecular Transport, Inc. | 2023-02-28 | Removed / first absent |
| Generation Bio Co. | Generation Bio Co. | 2024-02-29 | Removed / first absent |
| Repare Therapeutics, Inc. | Repare Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| Larimar Therapeutics, Inc. | Larimar Therapeutics, Inc. | 2023-02-28 | Removed / first absent |
| Compugen Ltd. | Compugen Ltd. | 2023-02-28 | Removed / first absent |
| I-Mab | I-Mab | 2024-02-29 | Removed / first absent |
| Pliant Therapeutics, Inc. | Pliant Therapeutics, Inc. | 2026-02-28 | Removed / first absent |
| Seagen, Inc. | Seagen, Inc. | 2024-02-29 | Removed / first absent |
| Annexon, Inc. | Annexon, Inc. | 2024-02-29 | Removed / first absent |
| Nkarta, Inc. | Nkarta, Inc. | 2024-02-29 | Removed / first absent |
| ALX Oncology Holdings, Inc. | ALX Oncology Holdings, Inc. | 2025-02-28 | Removed / first absent |
| Adicet Bio, Inc. | Adicet Bio, Inc. | 2024-02-29 | Removed / first absent |
| Chinook Therapeutics, Inc. | Chinook Therapeutics, Inc. | 2023-08-31 | Removed / first absent |
| Allovir, Inc. | Allovir, Inc. | 2024-02-29 | Removed / first absent |
| Marinus Pharmaceuticals, Inc. | Marinus Pharmaceuticals, Inc. | 2025-02-28 | Removed / first absent |
| Inozyme Pharma, Inc. | Inozyme Pharma, Inc. | 2022-02-28 | Removed / first absent |
| iTeos Therapeutics, Inc. | iTeos Therapeutics, Inc. | 2025-08-31 | Removed / first absent |
| Poseida Therapeutics, Inc. | Poseida Therapeutics, Inc. | 2024-02-29 | Removed / first absent |
| VYNE Therapeutics, Inc. | VYNE Therapeutics, Inc. | 2022-02-28 | Removed / first absent |
| Gamida Cell Ltd. | Gamida Cell Ltd. | 2023-02-28 | Removed / first absent |
| Kamada Ltd. | Kamada Ltd. | 2023-02-28 | Removed / first absent |